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Select item 95531231.

Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics

Natalia Akkuratova, Louis Faure, Polina Kameneva, Maria Eleni Kastriti, Igor Adameyko

Front Endocrinol (Lausanne) 2022; 13: 1020000. Published online 2022 Sep 27. doi: 10.3389/fendo.2022.1020000

PMCID:: PMC9553123

Abstract Article PDF–28M

Select item 87149762.

Salt sensitivity of volume and blood pressure in a mouse with globally reduced ENaC γ-subunit expression

Evan C. Ray, Ashley Pitzer, Tracey Lam, Alexa Jordahl, Ritam Patel, Mingfang Ao, Allison Marciszyn, Aaliyah Winfrey, Yaacov Barak, Shaohu Sheng, Annet Kirabo, Thomas R. Kleyman

Am J Physiol Renal Physiol. 2021 Dec 1; 321(6): F705–F714. Published online 2021 Oct 11. doi: 10.1152/ajprenal.00559.2020

PMCID:: PMC8714976

Abstract Article

Select item 85649133.

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency

Meng-Hsuan Lin, Jen-Chi Chen, Xuejiao Tian, Chia-Ming Lee, I-Shing Yu, Yi-Fen Lo, Shinichi Uchida, Chou-Long Huang, Bi-Chang Chen, Chih-Jen Cheng

JCI Insight. 2021 Oct 22; 6(20): e151039. Published online 2021 Oct 22. doi: 10.1172/jci.insight.151039

PMCID:: PMC8564913

Abstract Article PDF–6.6M

Select item 85354104.

Deletion of the Gamma Subunit of ENaC in Endothelial Cells Does Not Protect against Renal Ischemia Reperfusion Injury

Stephanie M. Mutchler, Mahpara Hasan, Donald E. Kohan, Thomas R. Kleyman, Roderick J. Tan

Int J Mol Sci. 2021 Oct; 22(20): 10914. Published online 2021 Oct 9. doi: 10.3390/ijms222010914

PMCID:: PMC8535410

Abstract Article PDF–2.5M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76631236.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Abstract Article PDF–4.7M

Select item 72174177.

Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct

Ali Sassi, Yubao Wang, Alexandra Chassot, Olga Komarynets, Isabelle Roth, Valérie Olivier, Gilles Crambert, Eva Dizin, Emilie Boscardin, Edith Hummler, Eric Feraille

J Am Soc Nephrol. 2020 May; 31(5): 1009–1023. Published online 2020 Apr 3. doi: 10.1681/ASN.2019080790

PMCID:: PMC7217417

Abstract Article

Select item 71527648.

Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel

Shujie Shi, Nicolas Montalbetti, Xueqi Wang, Brittney M. Rush, Allison L. Marciszyn, Catherine J. Baty, Roderick J. Tan, Marcelo D. Carattino, Thomas R. Kleyman

J Biol Chem. 2020 Apr 10; 295(15): 4950–4962. Published online 2020 Feb 20. doi: 10.1074/jbc.RA119.011789

PMCID:: PMC7152764

Abstract Article PDF–2.8M

Select item 63900579.

Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide-induced lung injury

Wang Deng, Chang-Yi Li, Jin Tong, Jing He, Yan Zhao, Dao-Xin Wang

Mol Med Rep. 2019 Mar; 19(3): 1665–1677. Published online 2019 Jan 2. doi: 10.3892/mmr.2019.9809

PMCID:: PMC6390057

Abstract Article PDF–2.6M

Select item 613370410.

Glucocorticoid receptor isoform–specific regulation of development, circadian rhythm, and inflammation in mice

Robert H. Oakley, Sivapriya Ramamoorthy, Julie F. Foley, Jonathan T. Busada, Nick Z. Lu, John A. Cidlowski

FASEB J. 2018 Oct; 32(10): 5258–5271. Published online 2018 Apr 19. doi: 10.1096/fj.201701153R

PMCID:: PMC6133704

Abstract Article

Select item 589922711.

Physiological regulation of the epithelial Na⁺ channel by casein kinase II

Jonathan M. Berman, Elena Mironova, James D. Stockand

Am J Physiol Renal Physiol. 2018 Mar 1; 314(3): F367–F372. Published online 2017 Oct 11. doi: 10.1152/ajprenal.00469.2017

PMCID:: PMC5899227

Abstract Article

Select item 589922112.

N-linked glycans are required on epithelial Na⁺ channel subunits for maturation and surface expression

Ossama B. Kashlan, Carol L. Kinlough, Michael M. Myerburg, Shujie Shi, Jingxin Chen, Brandon M. Blobner, Teresa M. Buck, Jeffrey L. Brodsky, Rebecca P. Hughey, Thomas R. Kleyman

Am J Physiol Renal Physiol. 2018 Mar 1; 314(3): F483–F492. Published online 2017 Nov 29. doi: 10.1152/ajprenal.00195.2017

PMCID:: PMC5899221

Abstract Article

Select item 582758813.

Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific γENaC Knockout

Emilie Boscardin, Romain Perrier, Chloé Sergi, Marc P. Maillard, Johannes Loffing, Dominique Loffing-Cueni, Robert Koesters, Bernard C. Rossier, Edith Hummler

J Am Soc Nephrol. 2018 Mar; 29(3): 977–990. Published online 2018 Jan 25. doi: 10.1681/ASN.2017030345

PMCID:: PMC5827588

Abstract Article

Select item 575227214.

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Marzia Scortegagna, Annabel Berthon, Nikolaos Settas, Andreas Giannakou, Guillermina Garcia, Jian-Liang Li, Brian James, Robert C. Liddington, José G. Vilches-Moure, Constantine A. Stratakis, Ze’ev A. Ronai

JCI Insight. 2017 Dec 7; 2(23): e97128. Published online 2017 Dec 7. doi: 10.1172/jci.insight.97128

PMCID:: PMC5752272

Abstract Article PDF–9.0M

Select item 540706715.

ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4^PHAII mice

Chengbiao Zhang, Lijun Wang, Xiao-Tong Su, Junhui Zhang, Dao-Hong Lin, Wen-Hui Wang

Am J Physiol Renal Physiol. 2017 Apr 1; 312(4): F682–F688. Published online 2016 Nov 9. doi: 10.1152/ajprenal.00420.2016

PMCID:: PMC5407067

Abstract Article

Select item 482965416.

Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes

Erin G. Reed-Geaghan, Margaret C. Wright, Lauren A. See, Peter C. Adelman, Kuan Hsien Lee, H. Richard Koerber, Stephen M. Maricich

J Neurosci. 2016 Apr 13; 36(15): 4362–4376. doi: 10.1523/JNEUROSCI.3781-15.2016

PMCID:: PMC4829654

Abstract Article PDF–6.3M

Select item 421698817.

Prostasin interacts with the epithelial Na⁺ channel and facilitates cleavage of the γ-subunit by a second protease

Marcelo D. Carattino, Gunhild M. Mueller, Lawrence G. Palmer, Gustavo Frindt, Anna C. Rued, Rebecca P. Hughey, Thomas R. Kleyman

Am J Physiol Renal Physiol. 2014 Nov 1; 307(9): F1080–F1087. Published online 2014 Sep 10. doi: 10.1152/ajprenal.00157.2014

PMCID:: PMC4216988

Abstract Article

Select item 419251418.

Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

Tengis S. Pavlov, Vladislav Levchenko, Alexander Staruschenko

J Biol Chem. 2014 Oct 10; 289(41): 28651–28659. Published online 2014 Aug 27. doi: 10.1074/jbc.M114.558262

PMCID:: PMC4192514

Abstract Article PDF–2.0M

Select item 413749119.

Blood Pressure and Amiloride-Sensitive Sodium Channels in Vascular and Renal Cells

David G. Warnock, Kristina Kusche-Vihrog, Antoine Tarjus, Shaohu Sheng, Hans Oberleithner, Thomas R. Kleyman, Frederic Jaisser

Nat Rev Nephrol. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Nat Rev Nephrol. 2014 Mar; 10(3): 146–157. Published online 2014 Jan 14. doi: 10.1038/nrneph.2013.275

PMCID:: PMC4137491

Abstract Article PDF–1.1M

Select item 390456620.

Sodium Transport Is Modulated by p38 Kinase–Dependent Cross-Talk between ENaC and Na,K-ATPase in Collecting Duct Principal Cells

Yu-Bao Wang, Valérie Leroy, Arvid B. Maunsbach, Alain Doucet, Udo Hasler, Eva Dizin, Thomas Ernandez, Sophie de Seigneux, Pierre-Yves Martin, Eric Féraille

J Am Soc Nephrol. 2014 Feb; 25(2): 250–259. Published online 2013 Oct 31. doi: 10.1681/ASN.2013040429

PMCID:: PMC3904566

Abstract Article

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