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Select item 105687851.

Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou

Cell Commun Signal. 2023; 21: 282. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01287-x

PMCID:: PMC10568785

Abstract Article PDF–12M

Select item 95048512.

Role of Caspases and Gasdermin A during HSV-1 Infection in Mice

Lupeng Li, Stephen B. Kovacs, Ine Jørgensen, Heather N. Larson, Helen M. Lazear, Edward A. Miao

Viruses. 2022 Sep; 14(9): 2034. Published online 2022 Sep 13. doi: 10.3390/v14092034

PMCID:: PMC9504851

Abstract Article PDF–2.2M

Select item 92470463.

Caspase-7 activates ASM to repair gasdermin and perforin pores

Kengo Nozaki, Vivien I. Maltez, Manira Rayamajhi, Alan L. Tubbs, Joseph E. Mitchell, Carolyn A. Lacey, Carissa K. Harvest, Lupeng Li, William T. Nash, Heather N. Larson, Benjamin D. McGlaughon, Nathaniel J. Moorman, Michael G. Brown, Jason K. Whitmire, Edward A. Miao

Nature. Author manuscript; available in PMC 2022 Dec 15.

Published in final edited form as: Nature. 2022 Jun; 606(7916): 960–967. Published online 2022 Jun 15. doi: 10.1038/s41586-022-04825-8

PMCID:: PMC9247046

Abstract Article PDF–9.4M

Select item 89016234.

Therapeutic potential of Nlrp1 inflammasome, Caspase-1, or Caspase-6 against Alzheimer disease cognitive impairment

Joseph Flores, Anastasia Noël, Marie-Lyne Fillion, Andréa C. LeBlanc

Cell Death Differ. 2022 Mar; 29(3): 657–669. Published online 2021 Oct 8. doi: 10.1038/s41418-021-00881-1

PMCID:: PMC8901623

Abstract Article PDF–5.1M

Select item 86336875.

Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections

Min Zheng, Rajendra Karki, Balabhaskararao Kancharana, Hartmut Berns, Shondra M. Pruett-Miller, Thirumala-Devi Kanneganti

J Biol Chem. 2021 Dec; 297(6): 101379. Published online 2021 Nov 2. doi: 10.1016/j.jbc.2021.101379

PMCID:: PMC8633687

Abstract Article PDF–1.6M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74252088.

Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense

Min Zheng, Rajendra Karki, Peter Vogel, Thirumala-Devi Kanneganti

Cell. Author manuscript; available in PMC 2021 Apr 30.

Published in final edited form as: Cell. 2020 Apr 30; 181(3): 674–687.e13. Published online 2020 Apr 15. doi: 10.1016/j.cell.2020.03.040

PMCID:: PMC7425208

Abstract Article PDF–2.7M

Select item 73433269.

Semaphorin-Mediated Corticospinal Axon Elimination Depends on the Activity-Induced Bax/Bak-Caspase Pathway

Zirong Gu, Natasha Koppel, John Kalamboglas, Gabriella Alexandrou, Jie Li, Corey Craig, David J. Simon, Marc Tessier-Lavigne, Mark L. Baccei, John H. Martin, Yutaka Yoshida

J Neurosci. 2020 Jul 8; 40(28): 5402–5412. doi: 10.1523/JNEUROSCI.3190-18.2020

PMCID:: PMC7343326

Abstract Article PDF–3.6M

Select item 703795010.

Caspase-6 Knockout in the 5xFAD Model of Alzheimer’s Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks

Ariel Angel, Rotem Volkman, Tabitha Grace Royal, Daniel Offen

Int J Mol Sci. 2020 Feb; 21(3): 1144. Published online 2020 Feb 9. doi: 10.3390/ijms21031144

PMCID:: PMC7037950

Abstract Article PDF–3.2M

Select item 681401411.

Regulation of B-lineage cells by caspase 6

Chie Watanabe, Geraldine L Shu, Natalia V Giltiay, Edward A Clark

Immunol Cell Biol. Author manuscript; available in PMC 2019 Oct 25.

Published in final edited form as: Immunol Cell Biol. 2018 Nov; 96(10): 1072–1082. Published online 2018 Jun 22. doi: 10.1111/imcb.12172

PMCID:: PMC6814014

Abstract Article PDF–1.4M

Select item 603005312.

Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6

Anastasia Noël, Libin Zhou, Bénédicte Foveau, P. Jesper Sjöström, Andréa C. LeBlanc

Cell Death Differ. 2018 Jul; 25(7): 1319–1335. Published online 2018 Jan 19. doi: 10.1038/s41418-017-0043-x

PMCID:: PMC6030053

Abstract Article PDF–6.2M

Select item 586277113.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 584589114.

Activation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis

Eva Svandova, Barbora Vesela, Abigail S. Tucker, Eva Matalova

Front Physiol. 2018; 9: 174. Published online 2018 Mar 7. doi: 10.3389/fphys.2018.00174

PMCID:: PMC5845891

Abstract Article PDF–9.6M

Select item 550149315.

Caspase-6 mediates resistance against Burkholderia pseudomallei infection and influences the expression of detrimental cytokines

Alexander Bartel, André Göhler, Verena Hopf, Katrin Breitbach

PLoS One. 2017; 12(7): e0180203. Published online 2017 Jul 7. doi: 10.1371/journal.pone.0180203

PMCID:: PMC5501493

Abstract Article PDF–3.2M

Select item 534420516.

Palmitoylation of caspase-6 by HIP14 regulates its activation

Niels H Skotte, Shaun S Sanders, Roshni R Singaraja, Dagmar E Ehrnhoefer, Kuljeet Vaid, Xiaofan Qiu, Srinivasaragavan Kannan, Chandra Verma, Michael R Hayden

Cell Death Differ. 2017 Mar; 24(3): 433–444. Published online 2016 Dec 2. doi: 10.1038/cdd.2016.139

PMCID:: PMC5344205

Abstract Article PDF–2.7M

Select item 501614117.

Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages

Yongfang Yao, Qian Shi, Bing Chen, Qingsong Wang, Xinda Li, Long Li, Yahong Huang, Jianguo Ji, Pingping Shen

J Biol Chem. 2016 Aug 12; 291(33): 17450–17466. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.717868

PMCID:: PMC5016141

Abstract Article PDF–5.3M

Select item 478346918.

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

Chao Yu, Shu-Yan Ji, Yu-Jiao Dang, Qian-Qian Sha, Yi-Feng Yuan, Jian-Jie Zhou, Li-Ying Yan, Jie Qiao, Fuchou Tang, Heng-Yu Fan

Cell Res. 2016 Mar; 26(3): 275–287. Published online 2016 Feb 23. doi: 10.1038/cr.2016.20

PMCID:: PMC4783469

Abstract Article PDF–9.2M

Select item 456378219.

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

V Kaushal, R Dye, P Pakavathkumar, B Foveau, J Flores, B Hyman, B Ghetti, B H Koller, A C LeBlanc

Cell Death Differ. 2015 Oct; 22(10): 1676–1686. Published online 2015 Mar 6. doi: 10.1038/cdd.2015.16

PMCID:: PMC4563782

Abstract Article PDF–2.6M

Select item 425500220.

Inflammation-Induced Tumorigenesis in Mouse Colon Is Caspase-6 Independent

Bénédicte Foveau, Lauren Van Der Kraak, Nicole Beauchemin, Steffen Albrecht, Andréa C. LeBlanc

PLoS One. 2014; 9(12): e114270. Published online 2014 Dec 3. doi: 10.1371/journal.pone.0114270

PMCID:: PMC4255002

Abstract Article PDF–4.4M

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