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Select item 100528041.

Overexpression of Notch Signaling in Renin Cells Leads to a Polycystic Kidney Phenotype

Brian C. Belyea, Fang Xu, Margaret Wiltsie, Hayes Fountain, Jennifer Charlton, Agnes B. Fogo, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez

Clin Sci (Lond) Author manuscript; available in PMC 2023 Mar 29.

Published in final edited form as: Clin Sci (Lond). 2023 Jan 13; 137(1): 35–45. doi: 10.1042/CS20220496

PMCID:: PMC10052804

Abstract Article PDF–3.2M

Select item 100177032.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 99279443.

A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension

Kushan L. Gunawardhana, Lingjuan Hong, Trojan Rugira, Severin Uebbing, Joanna Kucharczak, Sameet Mehta, Dineth R. Karunamuni, Brenda Cabera-Mendoza, Neeru Gandotra, Curt Scharfe, Renato Polimanti, James P. Noonan, Arya Mani

J Clin Invest. 2023 Feb 15; 133(4): e160036. Published online 2023 Feb 15. doi: 10.1172/JCI160036

PMCID:: PMC9927944

Abstract Article PDF–24M

Select item 93947824.

Essential role of Wtip in mouse development and maintenance of the glomerular filtration barrier

Sethu M. Madhavan, Martha Konieczkowski, Leslie A. Bruggeman, Megan DeWalt, Jane K. Nguyen, John F. O’Toole, John R. Sedor

Am J Physiol Renal Physiol. 2022 Sep 1; 323(3): F272–F287. Published online 2022 Jul 21. doi: 10.1152/ajprenal.00051.2022

PMCID:: PMC9394782

Abstract Article

Select item 91194065.

Advances in use of mouse models to study the renin-angiotensin system

Jacqueline M. Emathinger, Jonathan W. Nelson, Susan B. Gurley

Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Mol Cell Endocrinol. 2021 Jun 1; 529: 111255. Published online 2021 Mar 28. doi: 10.1016/j.mce.2021.111255

PMCID:: PMC9119406

Abstract Article PDF–518K

Select item 89137066.

Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells

Yuki Mochida, Koji Ochiai, Takashi Nagase, Keiko Nonomura, Yoshihiro Akimoto, Hiroshi Fukuhara, Tatsuo Sakai, George Matsumura, Yoshihiro Yamaguchi, Miki Nagase

Sci Rep. 2022; 12: 4197. Published online 2022 Mar 10. doi: 10.1038/s41598-022-07987-7

PMCID:: PMC8913706

Abstract Article PDF–7.0M

Select item 89068277.

Patterns of differentiation of renin lineage cells during nephrogenesis

Friederike Kessel, Anne Steglich, Linda Hickmann, Ricardo Lira Martinez, Michael Gerlach, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez, Christian P. M. Hugo, Vladimir T. Todorov

Am J Physiol Renal Physiol. 2021 Sep 1; 321(3): F378–F388. Published online 2021 Aug 2. doi: 10.1152/ajprenal.00151.2021

PMCID:: PMC8906827

Abstract Article

Select item 88437538.

Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse

Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty

J Clin Invest. 2022 Feb 15; 132(4): e153752. Published online 2022 Feb 15. doi: 10.1172/JCI153752

PMCID:: PMC8843753

Abstract Article PDF–4.9M

Select item 88130859.

Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia

Fenglin Wang, Jenny Ngo, Yuwen Li, Hongbing Liu, Chao-Hui Chen, Zubaida Saifudeen, Maria Luisa S Sequeira-Lopez, Samir S. El-Dahr

Epigenetics. 2021; 16(11): 1235–1250. Published online 2020 Dec 29. doi: 10.1080/15592294.2020.1861168

PMCID:: PMC8813085

Abstract Article PDF–6.2M

Select item 880759510.

Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma

Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi, Ryuichi Nishinakamura

Nat Commun. 2022; 13: 611. Published online 2022 Feb 1. doi: 10.1038/s41467-022-28226-7

Correction in:: Nat Commun. 2023; 14: 1874.

PMCID:: PMC8807595

Abstract Article PDF–5.4M

Select item 861954911.

In Vivo Renin Activity Imaging in the Kidney of Progeroid Ercc1 Mutant Mice

Bibi S. van Thiel, Janette van der Linden, Yanto Ridwan, Ingrid M. Garrelds, Marcel Vermeij, Marian C. Clahsen-van Groningen, Fatimunnisa Qadri, Natalia Alenina, Michael Bader, Anton J. M. Roks, A. H. Jan Danser, Jeroen Essers, Ingrid van der Pluijm

Int J Mol Sci. 2021 Nov; 22(22): 12433. Published online 2021 Nov 18. doi: 10.3390/ijms222212433

PMCID:: PMC8619549

Abstract Article PDF–2.0M

Select item 856594312.

Sex Differences in Blood Pressure of Aged Ren-2 Transgenic Rats

Hana RAUCHOVÁ, Silvie HOJNÁ, Michaela KADLECOVÁ, Ivana VANĚČKOVÁ, Josef ZICHA

Physiol Res. 2020 Apr; 69(2): 245–252. Published online 2020 Mar 23. doi: 10.33549/physiolres.934369

PMCID:: PMC8565943

Abstract Article PDF–376K

Select item 846683513.

Intermittent Hypoxia Upregulates the Renin and Cd38 mRNAs in Renin-Producing Cells via the Downregulation of miR-203

Yoshinori Takeda, Asako Itaya-Hironaka, Akiyo Yamauchi, Mai Makino, Sumiyo Sakuramoto-Tsuchida, Hiroyo Ota, Ryuji Kawaguchi, Shin Takasawa

Int J Mol Sci. 2021 Sep; 22(18): 10127. Published online 2021 Sep 19. doi: 10.3390/ijms221810127

PMCID:: PMC8466835

Abstract Article PDF–2.6M

Select item 846391014.

Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system

Han Su, Ning Liu, Yalin Zhang, Juan Kong

J Adv Res. 2021 Nov; 33: 69–80. Published online 2021 Feb 2. doi: 10.1016/j.jare.2021.01.011

PMCID:: PMC8463910

Abstract Article PDF–3.8M

Select item 845597315.

Olfactory receptor 78 modulates renin but not baseline blood pressure

Brian G. Poll, Jiaojiao Xu, Kunal Gupta, Tyler B. Shubitowski, Jennifer L. Pluznick

Physiol Rep. 2021 Sep; 9(18): e15017. Published online 2021 Sep 21. doi: 10.14814/phy2.15017

PMCID:: PMC8455973

Abstract Article PDF–937K

Select item 831824416.

Studies of salt and stress sensitivity on arterial pressure in renin-b deficient mice

Pablo Nakagawa, Javier Gomez, Ko-Ting Lu, Justin L. Grobe, Curt D. Sigmund

PLoS One. 2021; 16(7): e0250807. Published online 2021 Jul 28. doi: 10.1371/journal.pone.0250807

PMCID:: PMC8318244

Abstract Article PDF–3.0M

Select item 827351617.

Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells

Pauline Sararols, Isabelle Stévant, Yasmine Neirijnck, Diane Rebourcet, Annalucia Darbey, Michael K. Curley, Françoise Kühne, Emmanouil Dermitzakis, Lee B. Smith, Serge Nef

Front Cell Dev Biol. 2021; 9: 695546. Published online 2021 Jun 28. doi: 10.3389/fcell.2021.695546

PMCID:: PMC8273516

Abstract Article PDF–8.1M

Select item 827313518.

The Renin Cell Baroreceptor, A Nuclear Mechanotransducer Central for Homeostasis

Hirofumi Watanabe, Brian C. Belyea, Robert L. Paxton, Minghong Li, Bette J. Dzamba, Douglas W. DeSimone, R. Ariel Gomez, Maria Luisa S. Sequeira-Lopez

Circ Res. Author manuscript; available in PMC 2022 Jul 9.

Published in final edited form as: Circ Res. 2021 Jul 9; 129(2): 262–276. Published online 2021 May 17. doi: 10.1161/CIRCRESAHA.120.318711

PMCID:: PMC8273135

Abstract Article PDF–2.8M

Select item 788137019.

Ctcf is Required for Renin Expression and Maintenance of the Structural Integrity of the Kidney

Maria Florencia Martinez, Alexandre G. Martini, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez

Clin Sci (Lond) Author manuscript; available in PMC 2021 Feb 13.

Published in final edited form as: Clin Sci (Lond). 2020 Jul 17; 134(13): 1763–1774. doi: 10.1042/CS20200184

PMCID:: PMC7881370

Abstract Article PDF–2.5M

Select item 786577920.

Alteration of Cx37, Cx40, Cx43, Cx45, Panx1, and Renin Expression Patterns in Postnatal Kidneys of Dab1-/- (yotari) Mice

Mirela Lozić, Natalija Filipović, Marija Jurić, Ivona Kosović, Benjamin Benzon, Ivana Šolić, Nela Kelam, Anita Racetin, Koichiro Watanabe, Yu Katsuyama, Masaki Ogata, Mirna Saraga-Babić, Katarina Vukojević

Int J Mol Sci. 2021 Feb; 22(3): 1284. Published online 2021 Jan 28. doi: 10.3390/ijms22031284