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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105710292.

Roles of lipocalin-type and hematopoietic prostaglandin D synthases in mouse retinal angiogenesis

Daiki Horikami, Erika Sekihachi, Keisuke Omori, Yui Kobayashi, Koji Kobayashi, Nanae Nagata, Kaori Kurata, Akiyoshi Uemura, Takahisa Murata

J Lipid Res. 2023 Oct; 64(10): 100439. Published online 2023 Sep 4. doi: 10.1016/j.jlr.2023.100439

PMCID:: PMC10571029

Abstract Article PDF–4.0M

Select item 85465563.

Differential Effects of Prostaglandin D₂ Signaling on Macrophages and Microglia in Murine Coronavirus Encephalomyelitis

Abhishek Kumar Verma, Jian Zheng, Matthias Mack, Florent Ginhoux, Stanley Perlman

mBio. 2021 Sep-Oct; 12(5): e01969-21. Published online 2021 Sep 7. doi: 10.1128/mBio.01969-21

PMCID:: PMC8546556

Abstract Article PDF–4.1M

Select item 83636044.

In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Kyle D. Duncan, Xiaofei Sun, Erin S. Baker, Sudhansu K. Dey, Ingela Lanekoff

Commun Biol. 2021; 4: 966. Published online 2021 Aug 13. doi: 10.1038/s42003-021-02488-1

Correction in:: Commun Biol. 2021; 4: 1010.

PMCID:: PMC8363604

Abstract Article PDF–1.9M

Select item 75198875.

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis

Nicholas S Kirkby, Joan Raouf, Blerina Ahmetaj-Shala, Bin Liu, Sarah I Mazi, Matthew L Edin, Mark Geoffrey Chambers, Marina Korotkova, Xiaomeng Wang, Walter Wahli, Darryl C Zeldin, Rolf Nüsing, Yingbi Zhou, Per-Johan Jakobsson, Jane A Mitchell

Cardiovasc Res. 2020 Oct 1; 116(12): 1972–1980. Published online 2019 Nov 5. doi: 10.1093/cvr/cvz290

PMCID:: PMC7519887

Abstract Article PDF–928K

Select item 73322826.

Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE

Jian Zheng, Alan Sariol, David Meyerholz, Qinran Zhang, Juan E. Abrahante Lloréns, Shuh Narumiya, Stanley Perlman

J Autoimmun. 2020 Nov; 114: 102508. Published online 2020 Jul 2. doi: 10.1016/j.jaut.2020.102508

PMCID:: PMC7332282

Abstract Article PDF–13M

Select item 72333407.

Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling

Yuhu He, Caojian Zuo, Daile Jia, Peiyuan Bai, Deping Kong, Di Chen, Guizhu Liu, Juanjuan Li, Yuanyang Wang, Guilin Chen, Shuai Yan, Bing Xiao, Jian Zhang, Lingjuan Piao, Yanli Li, Yi Deng, Bin Li, Philippe P. Roux, Katrin I. Andreasson, Richard M. Breyer, Yunchao Su, Jian Wang, Ankang Lyu, Yujun Shen, Ying Yu

Am J Respir Crit Care Med. 2020 May 15; 201(10): 1263–1276. Published online 2020 May 15. doi: 10.1164/rccm.201911-2137OC

PMCID:: PMC7233340

Abstract Article PDF–2.5M

Select item 66739868.

Prostaglandin D₂-Mediated Microglia/Astrocyte Interaction Enhances Astrogliosis and Demyelination in twitcher

Ikuko Mohri, Masako Taniike, Hidetoshi Taniguchi, Takahisa Kanekiyo, Kosuke Aritake, Takashi Inui, Noriko Fukumoto, Naomi Eguchi, Atsuko Kushi, Hitoshi Sasai, Yoshihide Kanaoka, Keiichi Ozono, Shuh Narumiya, Kinuko Suzuki, Yoshihiro Urade

J Neurosci. 2006 Apr 19; 26(16): 4383–4393. doi: 10.1523/JNEUROSCI.4531-05.2006

PMCID:: PMC6673986

Abstract Article PDF–1.9M

Select item 66723049.

Prostaglandin D₂ Protects Neonatal Mouse Brain from Hypoxic Ischemic Injury

Hidetoshi Taniguchi, Ikuko Mohri, Hitomi Okabe-Arahori, Kosuke Aritake, Kazuko Wada, Takahisa Kanekiyo, Shuh Narumiya, Masahiro Nakayama, Keiichi Ozono, Yoshihiro Urade, Masako Taniike

J Neurosci. 2007 Apr 18; 27(16): 4303–4312. doi: 10.1523/JNEUROSCI.0321-07.2007

PMCID:: PMC6672304

Abstract Article PDF–566K

Select item 643360010.

Sustained exposure to prostaglandin D₂ augments the contraction induced by acetylcholine via a DP₁ receptor-mediated activation of p38 in bronchial smooth muscle of naive mice

Wataru Suto, Hiroyasu Sakai, Yoshihiko Chiba

J Smooth Muscle Res. 2019; 55: 1–13. Published online 2019 Mar 26. doi: 10.1540/jsmr.55.1

PMCID:: PMC6433600

Abstract Article PDF–1.0M

Select item 558534811.

Decidualisation and placentation defects are a major cause of age-related reproductive decline

Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger

Nat Commun. 2017; 8: 352. Published online 2017 Sep 5. doi: 10.1038/s41467-017-00308-x

PMCID:: PMC5585348

Abstract Article PDF–4.3M

Select item 550263012.

Virus-induced inflammasome activation is suppressed by prostaglandin D₂/DP1 signaling

Rahul Vijay, Anthony R. Fehr, Ann M. Janowski, Jeremiah Athmer, Dorthea L. Wheeler, Matthew Grunewald, Ramakrishna Sompallae, Samarchith P. Kurup, David K. Meyerholz, Fayyaz S. Sutterwala, Shuh Narumiya, Stanley Perlman

Proc Natl Acad Sci U S A. 2017 Jul 3; 114(27): E5444–E5453. Published online 2017 Jun 19. doi: 10.1073/pnas.1704099114

PMCID:: PMC5502630

Abstract Article PDF–1.5M

Select item 541279213.

Niacin ameliorates ulcerative colitis via prostaglandin D₂‐mediated D prostanoid receptor 1 activation

Juanjuan Li, Deping Kong, Qi Wang, Wei Wu, Yanping Tang, Tingting Bai, Liang Guo, Lumin Wei, Qianqian Zhang, Yu Yu, Yuting Qian, Shengkai Zuo, Guizhu Liu, Qian Liu, Sheng Wu, Yi Zang, Qian Zhu, Daile Jia, Yuanyang Wang, Weiyan Yao, Yong Ji, Huiyong Yin, Masataka Nakamura, Michael Lazarus, Richard M Breyer, Lifu Wang, Ying Yu

EMBO Mol Med. 2017 May; 9(5): 571–588. Published online 2017 Mar 27. doi: 10.15252/emmm.201606987

Correction in:: EMBO Mol Med. 2020 Dec 7; 12(12): e13487.

PMCID:: PMC5412792

Abstract Article PDF–2.4M

Select item 503080614.

PKA regulatory IIα subunit is essential for PGD₂-mediated resolution of inflammation

Deping Kong, Yujun Shen, Guizhu Liu, Shengkai Zuo, Yong Ji, Ankang Lu, Masataka Nakamura, Michael Lazarus, Constantine A. Stratakis, Richard M. Breyer, Ying Yu

J Exp Med. 2016 Sep 19; 213(10): 2209–2226. doi: 10.1084/jem.20160459

PMCID:: PMC5030806

Abstract Article PDF–4.1M

Select item 430317315.

Intestinal tumor suppression in Apc^Min/+ mice by prostaglandin D₂ receptor PTGDR

Brigette L Tippin, Alan M Kwong, Michael J Inadomi, Oliver J Lee, Jae Man Park, Alicia M Materi, Virgilio S Buslon, Amy M Lin, Lili C Kudo, Stanislav L Karsten, Samuel W French, Shuh Narumiya, Yoshihiro Urade, Eduardo Salido, Henry J Lin

Cancer Med. 2014 Aug; 3(4): 1041–1051. Published online 2014 Apr 12. doi: 10.1002/cam4.251

PMCID:: PMC4303173

Abstract Article PDF–2.1M

Select item 406530716.

Mast cell maturation is driven via a group III phospholipase A₂-prostaglandin D₂–DP1 receptor paracrine axis

Yoshitaka Taketomi, Noriko Ueno, Takumi Kojima, Hiroyasu Sato, Remi Murase, Kei Yamamoto, Satoshi Tanaka, Mariko Sakanaka, Masanori Nakamura, Yasumasa Nishito, Momoko Kawana, Naotomo Kambe, Kazutaka Ikeda, Ryo Taguchi, Satoshi Nakamizo, Kenji Kabashima, Michael H. Gelb, Makoto Arita, Takehiko Yokomizo, Motonao Nakamura, Kikuko Watanabe, Hiroyuki Hirai, Masataka Nakamura, Yoshimichi Okayama, Chisei Ra, Kosuke Aritake, Yoshihiro Urade, Kazushi Morimoto, Yukihiko Sugimoto, Takao Shimizu, Shuh Narumiya, Shuntaro Hara, Makoto Murakami

Nat Immunol. Author manuscript; available in PMC 2014 Jun 21.

Published in final edited form as: Nat Immunol. 2013 Jun; 14(6): 554–563. Published online 2013 Apr 28. doi: 10.1038/ni.2586

PMCID:: PMC4065307

Abstract Article PDF–1.0M

Select item 396495517.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 359376118.

Prostaglandin D₂ inhibits wound-induced hair follicle neogenesis through the receptor, Gpr44

Amanda M. Nelson, Dorothy E. Loy, John A. Lawson, Adiya S. Katseff, Garret A. FitzGerald, Luis A. Garza

J Invest Dermatol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: J Invest Dermatol. 2013 Apr; 133(4): 881–889. Published online 2012 Nov 29. doi: 10.1038/jid.2012.398

PMCID:: PMC3593761

Abstract Article PDF–1.2M

Select item 352052319.

Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis

Alison M. Strack, Ester Carballo-Jane, Sheng-ping Wang, Jiyan Xue, Xiaoli Ping, Lesley Ann McNamara, Anil Thankappan, Olga Price, Michael Wolff, T. J. Wu, Douglas Kawka, Michele Mariano, Charlotte Burton, Ching H. Chang, Jing Chen, John Menke, Silvi Luell, Emanuel I. Zycband, Xinchun Tong, Richard Raubertas, Carl P. Sparrow, Brian Hubbard, John Woods, Gary O'Neill, M. Gerard Waters, Ayesha Sitlani

J Lipid Res. 2013 Jan; 54(1): 177–188. doi: 10.1194/jlr.M031344

PMCID:: PMC3520523

Abstract Article PDF–1.3M

Select item 331997520.

Prostaglandin D₂ Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

Luis A. Garza, Yaping Liu, Zaixin Yang, Brinda Alagesan, John A. Lawson, Scott M. Norberg, Dorothy E. Loy, Tailun Zhao, Hanz B. Blatt, David C. Stanton, Lee Carrasco, Gurpreet Ahluwalia, Susan M. Fischer, Garret A. FitzGerald, George Cotsarelis

Sci Transl Med. Author manuscript; available in PMC 2012 Apr 5.

Published in final edited form as: Sci Transl Med. 2012 Mar 21; 4(126): 126ra34. doi: 10.1126/scitranslmed.3003122

PMCID:: PMC3319975

Abstract Article PDF–3.3M

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