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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 92537543.

Glyoxalase 1 knockdown induces age‐related β‐cell dysfunction and glucose intolerance in mice

Immacolata Prevenzano, Alessia Leone, Michele Longo, Antonella Nicolò, Serena Cabaro, Francesca Collina, Iacopo Panarese, Gerardo Botti, Pietro Formisano, Raffaele Napoli, Francesco Beguinot, Claudia Miele, Cecilia Nigro

EMBO Rep. 2022 Jul; 23(7): e52990. Published online 2022 May 27. doi: 10.15252/embr.202152990

PMCID:: PMC9253754

Abstract Article PDF–2.1M

Select item 87442574.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 85803075.

High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice

Shinobu Hirai, Hideki Miwa, Tomoko Tanaka, Kazuya Toriumi, Yasuto Kunii, Hiroko Shimbo, Takuya Sakamoto, Mizuki Hino, Ryuta Izumi, Atsuko Nagaoka, Hirooki Yabe, Tomoya Nakamachi, Seiji Shioda, Takashi Dan, Toshio Miyata, Yasumasa Nishito, Kazuhiro Suzuki, Mitsuhiro Miyashita, Toshifumi Tomoda, Takatoshi Hikida, Junjiro Horiuchi, Masanari Itokawa, Makoto Arai, Haruo Okado

Sci Adv. 2021 Nov; 7(46): eabl6077. Published online 2021 Nov 10. doi: 10.1126/sciadv.abl6077

PMCID:: PMC8580307

Abstract Article PDF–1.4M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82539147.

Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex

Kazuya Toriumi, Stefano Berto, Shin Koike, Noriyoshi Usui, Takashi Dan, Kazuhiro Suzuki, Mitsuhiro Miyashita, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Kenichiro Nagahama, Hsiao-Chun Lin, Yuki Sugaya, Takaki Watanabe, Masanobu Kano, Yuki Ogasawara, Toshio Miyata, Masanari Itokawa, Genevieve Konopka, Makoto Arai

Redox Biol. 2021 Sep; 45: 102057. Published online 2021 Jun 24. doi: 10.1016/j.redox.2021.102057

PMCID:: PMC8253914

Abstract Article PDF–3.8M

Select item 80682918.

Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits

Shin Koike, Kazuya Toriumi, Sakura Kasahara, Yosuke Kibune, Yo-ichi Ishida, Takashi Dan, Toshio Miyata, Makoto Arai, Yuki Ogasawara

Antioxidants (Basel) 2021 Apr; 10(4): 574. Published online 2021 Apr 8. doi: 10.3390/antiox10040574

PMCID:: PMC8068291

Abstract Article PDF–4.2M

Select item 74159919.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 672510010.

Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety

Simone A. Krömer, Melanie S. Keßler, Dale Milfay, Isabel N. Birg, Mirjam Bunck, Ludwig Czibere, Markus Panhuysen, Benno Pütz, Jan M. Deussing, Florian Holsboer, Rainer Landgraf, Christoph W. Turck

J Neurosci. 2005 Apr 27; 25(17): 4375–4384. doi: 10.1523/JNEUROSCI.0115-05.2005

PMCID:: PMC6725100

Abstract Article PDF–689K

Select item 662390811.

Role of the Glyoxalase System in Astrocyte-Mediated Neuroprotection

Mireille Bélanger, Jiangyan Yang, Jean-Marie Petit, Thierry Laroche, Pierre J. Magistretti, Igor Allaman

J Neurosci. 2011 Dec 14; 31(50): 18338–18352. doi: 10.1523/JNEUROSCI.1249-11.2011

PMCID:: PMC6623908

Abstract Article PDF–2.1M

Select item 661001612.

Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes

Hainan Li, Megan O’Meara, Xiang Zhang, Kezhong Zhang, Berhane Seyoum, Zhengping Yi, Randal J. Kaufman, Terrence J. Monks, Jie-Mei Wang

Diabetes. 2019 Jun; 68(6): 1287–1302. Published online 2019 Mar 18. doi: 10.2337/db18-0933

PMCID:: PMC6610016

Abstract Article PDF–3.1M

Select item 645951013.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 626277714.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 591591715.

Glyoxalase (GLO1) inhibition or genetic overexpression does not alter ethanol’s locomotor effects: implications for GLO1 as a therapeutic target in alcohol use disorders

Amanda M Barkley-Levenson, Frances A Lagarda, Abraham A Palmer

Alcohol Clin Exp Res. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Alcohol Clin Exp Res. 2018 May; 42(5): 869–878. Published online 2018 Apr 18. doi: 10.1111/acer.13623

PMCID:: PMC5915917

Abstract Article PDF–1.1M

Select item 544273016.

Glyoxalase‐1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose‐Derived Stem Cells in Streptozotocin‐Induced Diabetic Mice Model of Critical Limb Ischemia

Zhiyou Peng, Xinrui Yang, Jinbao Qin, Kaichuang Ye, Xin Wang, Huihua Shi, Mier Jiang, Xiaobing Liu, Xinwu Lu

Stem Cells Transl Med. 2017 Jan; 6(1): 261–271. Published online 2016 Aug 15. doi: 10.5966/sctm.2015-0380

PMCID:: PMC5442730

Abstract Article PDF–4.9M

Select item 533615817.

Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells

Jakob Morgenstern, Thomas Fleming, Dagmar Schumacher, Volker Eckstein, Marc Freichel, Stephan Herzig, Peter Nawroth

J Biol Chem. 2017 Feb 24; 292(8): 3224–3238. Published online 2016 Dec 12. doi: 10.1074/jbc.M116.760132

PMCID:: PMC5336158

Abstract Article PDF–2.6M

Select item 491747018.

Genetic and pharmacological manipulation of Glyoxalase 1 regulates voluntary ethanol consumption in mice

Katherine M. J. McMurray, Preetpal S. Sidhu, James M. Cook, Leggy A. Arnold, Abraham A. Palmer

Addict Biol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Addict Biol. 2017 Mar; 22(2): 381–389. Published online 2015 Dec 22. doi: 10.1111/adb.12333

PMCID:: PMC4917470

Abstract Article PDF–687K

Select item 469302319.

A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

Markus Wortmann, Maani Hakimi, Thomas Fleming, Andreas S. Peters, Tjeerd P. Sijmonsma, Stephan Herzig, Peter P. Nawroth, Dittmar Böckler, Susanne Dihlmann

J Diabetes Res. 2016; 2016: 2981639. Published online 2015 Dec 15. doi: 10.1155/2016/2981639

PMCID:: PMC4693023

Abstract Article PDF–2.4M

Select item 456197520.

Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor

Hong Zhang, Qiang Huang, Jing Zhai, Yi-ning Zhao, Li-ping Zhang, Yun-yun Chen, Ren-wei Zhang, Qing Li, Xiao-peng Hu

Acta Pharmacol Sin. 2015 Sep; 36(9): 1145–1150. Published online 2015 Aug 17. doi: 10.1038/aps.2015.59

PMCID:: PMC4561975

Abstract Article PDF–931K

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