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Select item 110084821.

The crucial relationship between miRNA-27 and CSE/H₂S, and the mechanism of action of GLP-1 in myocardial hypertrophy

Shan Gao, Ying Li, Mei-ming Liu, Xue Xiong, Chang-peng Cui, Qing-ji Huo, Ke-xin Li, Xun Sun, Rong Zhang, Di Wu, Bai-yan Li

Int J Med Sci. 2024; 21(5): 965–977. Published online 2024 Mar 31. doi: 10.7150/ijms.93720

PMCID:: PMC11008482

Abstract Article PDF–5.6M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107929553.

Loss of cardiac mitochondrial complex I persulfidation impairs NAD⁺ homeostasis in aging

Maria-Kyriaki Drekolia, Christina Karantanou, Ilka Wittig, Yuanyuan Li, Dominik C. Fuhrmann, Bernhard Brüne, Antonia Katsouda, Jiong Hu, Andreas Papapetropoulos, Sofia-Iris Bibli

Redox Biol. 2024 Feb; 69: 103014. Published online 2023 Dec 25. doi: 10.1016/j.redox.2023.103014

PMCID:: PMC10792955

Abstract Article PDF–5.5M

Select item 104878724.

Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells

Sumeet Manandhar, Stephen Chambers, Andrew Miller, Isao Ishii, Madhav Bhatia

Int J Mol Sci. 2023 Sep; 24(17): 13650. Published online 2023 Sep 4. doi: 10.3390/ijms241713650

PMCID:: PMC10487872

Abstract Article PDF–67M

Select item 103634445.

Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation

Maria Peleli, Ivi Antoniadou, Dorival Mendes Rodrigues-Junior, Odysseia Savvoulidou, Laia Caja, Antonia Katsouda, Daniel F.J. Ketelhuth, Jane Stubbe, Kirsten Madsen, Aristidis Moustakas, Andreas Papapetropoulos

Redox Biol. 2023 Aug; 64: 102773. Published online 2023 Jun 5. doi: 10.1016/j.redox.2023.102773

PMCID:: PMC10363444

Abstract Article PDF–9.3M

Select item 99690966.

CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway

Antonia Katsouda, Maria Markou, Paraskevas Zampas, Aimilia Varela, Constantinos H. Davos, Valentina Vellecco, Giuseppe Cirino, Mariarosaria Bucci, Andreas Papapetropoulos

Front Pharmacol. 2023; 14: 1090654. Published online 2023 Feb 13. doi: 10.3389/fphar.2023.1090654

PMCID:: PMC9969096

Abstract Article PDF–1.6M

Select item 98696347.

Cystathionine gamma-lyase (Cth) induces efferocytosis in macrophages via ERK1/2 to modulate intestinal barrier repair

Xiao-Hu Zhao, Ting Yang, Meng-Yao Zheng, Peinan Zhao, Li-Ya An, Yu-Xing Qi, Ke-Qian Yi, Peng-Cheng Zhang, Da-Li Sun

Cell Commun Signal. 2023; 21: 17. Published online 2023 Jan 23. doi: 10.1186/s12964-022-01030-y

PMCID:: PMC9869634

Abstract Article PDF–11M

Select item 97959018.

Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor

Wenjing Xu, Changting Cui, Chunmei Cui, Zhenzhen Chen, Haizeng Zhang, Qinghua Cui, Guoheng Xu, Jianglin Fan, Yu Han, Liangjie Tang, Giovanni Targher, Christopher D. Byrne, Ming‐Hua Zheng, Liming Yang, Jun Cai, Bin Geng

Hepatology. 2022 Dec; 76(6): 1794–1810. Published online 2022 Jun 30. doi: 10.1002/hep.32577

PMCID:: PMC9795901

Abstract Article PDF–95M

Select item 96736479.

Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt‐Dependent Mechanism

Junya Suzuki, Yuuki Shimizu, Takumi Hayashi, Yiyang Che, Zhongyue Pu, Kazuhito Tsuzuki, Shingo Narita, Rei Shibata, Isao Ishii, John W. Calvert, Toyoaki Murohara

J Am Heart Assoc. 2022 Nov 1; 11(21): e026889. Published online 2022 Oct 26. doi: 10.1161/JAHA.122.026889

PMCID:: PMC9673647

Abstract Article PDF–2.4M

Select item 935784110.

Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis

Ketan K. Thanki, Paul Johnson, Edward J. Higgins, Manjit Maskey, Ches’Nique Phillips, Swetaleena Dash, Francisco Arroyo Almenas, Armita Abdollahi Govar, Bing Tian, Romain Villéger, Ellen Beswick, Rui Wang, Csaba Szabo, Celia Chao, Irina V. Pinchuk, Mark R. Hellmich, Katalin Módis

Redox Biol. 2022 Sep; 55: 102417. Published online 2022 Jul 21. doi: 10.1016/j.redox.2022.102417

PMCID:: PMC9357841

Abstract Article PDF–8.3M

Select item 925058911.

Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice

Hiroyuki Yamaguchi, Matthew D. Meyer, Li He, Yoshihiro Komatsu

Dev Dyn. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Dev Dyn. 2022 Jul; 251(7): 1209–1222. Published online 2022 Feb 18. doi: 10.1002/dvdy.461

PMCID:: PMC9250589

Abstract Article PDF–2.3M

Select item 894133712.

Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation

Diane Macabrey, Alban Longchamp, Michael R. MacArthur, Martine Lambelet, Severine Urfer, Sebastien Deglise, Florent Allagnat

EBioMedicine. 2022 Apr; 78: 103954. Published online 2022 Mar 22. doi: 10.1016/j.ebiom.2022.103954

PMCID:: PMC8941337

Abstract Article PDF–6.8M

Select item 877848613.

A High-Methionine Diet for One-Week Induces a High Accumulation of Methionine in the Cerebrospinal Fluid and Confers Bipolar Disorder-like Behavior in Mice

Isao Ishii, Shotaro Kamata, Saki Ito, Aya Shimonaga, Maika Koizumi, Maiko Tsushima, Asumi Miura, Tomoko Nagata, Yuka Tosaka, Haruka Ohtani, Waka Kamichatani, Noriyuki Akahoshi

Int J Mol Sci. 2022 Jan; 23(2): 928. Published online 2022 Jan 15. doi: 10.3390/ijms23020928

PMCID:: PMC8778486

Abstract Article PDF–2.0M

Select item 865122714.

The DR1-CSE/H₂S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice

Hongzhu Li, Fengqi Sun, Shuzhi Bai, Guiquan Chang, Ren Wu, Yaxin Wei, Xin Wen, Yuxin Xi, Jinghui Hao, Altaany Zaid

Int J Mol Med. 2022 Jan; 49(1): 7. Published online 2021 Nov 11. doi: 10.3892/ijmm.2021.5062

PMCID:: PMC8651227

Abstract Article PDF–6.4M

Select item 816884615.

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

Monica Sueiro-Olivares, Jennifer Scott, Sara Gago, Dunja Petrovic, Emilia Kouroussis, Jasmina Zivanovic, Yidong Yu, Marlene Strobel, Cristina Cunha, Darren Thomson, Rachael Fortune-Grant, Sina Thusek, Paul Bowyer, Andreas Beilhack, Agostinho Carvalho, Elaine Bignell, Milos R. Filipovic, Jorge Amich

PLoS Biol. 2021 Jun; 19(6): e3001247. Published online 2021 Jun 1. doi: 10.1371/journal.pbio.3001247

Correction in:: PLoS Biol. 2021 Aug; 19(8): e3001381.

PMCID:: PMC8168846

Abstract Article PDF–2.3M

Select item 793877016.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 789685317.

Hydrogen Sulfide Is a Regulator of Hemoglobin Oxygen-Carrying Capacity via Controlling 2,3-BPG Production in Erythrocytes

Gang Wang, Yan Huang, Ningning Zhang, Wenhu Liu, Changnan Wang, Xiaoyan Zhu, Xin Ni

Oxid Med Cell Longev. 2021; 2021: 8877691. Published online 2021 Feb 13. doi: 10.1155/2021/8877691

PMCID:: PMC7896853

Abstract Article PDF–1.9M

Select item 771649318.

CSE/H₂S system alleviates uremic accelerated atherosclerosis by regulating TGF-β/Smad3 pathway in 5/6 nephrectomy ApoE^−/− mice

Xiangxue Lu, Shixiang Wang, Sujuan Feng, Han Li

BMC Nephrol. 2020; 21: 527. Published online 2020 Dec 4. doi: 10.1186/s12882-020-02183-z

PMCID:: PMC7716493

Abstract Article PDF–1.0M

Select item 768099919.

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis

Katalin Módis, V-M. Sadagopa Ramanujam, Armita Abdollahi Govar, Ernesto Lopez, Karl E. Anderson, Rui Wang, Csaba Szabo

Biochem Pharmacol. Author manuscript; available in PMC 2020 Nov 23.

Published in final edited form as: Biochem Pharmacol. 2019 Nov; 169: 113604. Published online 2019 Aug 14. doi: 10.1016/j.bcp.2019.08.006

PMCID:: PMC7680999

Abstract Article PDF–1.7M

Select item 703811720.

Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria

Noriyuki Akahoshi, Tatsuro Minakawa, Masashi Miyashita, Uran Sugiyama, Chihiro Saito, Rintaro Takemoto, Akihiro Honda, Waka Kamichatani, Shotaro Kamata, Yasumi Anan, Isao Ishii

Int J Mol Sci. 2020 Feb; 21(3): 818. Published online 2020 Jan 27. doi: 10.3390/ijms21030818

PMCID:: PMC7038117

Abstract Article PDF–1.9M

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