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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105024152.

Spatially distinct otic mesenchyme cells show molecular and functional heterogeneity patterns before hearing onset

Kevin P. Rose, Gabriella Manilla, Beatrice Milon, Ori Zalzman, Yang Song, Thomas M. Coate, Ronna Hertzano

iScience. 2023 Oct 20; 26(10): 107769. Published online 2023 Aug 29. doi: 10.1016/j.isci.2023.107769

PMCID:: PMC10502415

Abstract Article PDF–15M

Select item 104867283.

Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1

Mona Veithen, Aurélia Huyghe, Priscilla Van Den Ackerveken, So-ichiro Fukada, Hiroki Kokubo, Ingrid Breuskin, Laurent Nguyen, Laurence Delacroix, Brigitte Malgrange

Cells. 2023 Sep; 12(17): 2148. Published online 2023 Aug 25. doi: 10.3390/cells12172148

PMCID:: PMC10486728

Abstract Article PDF–5.3M

Select item 102341094.

GIPC3 couples to MYO6 and PDZ domain proteins, and shapes the hair cell apical region

Paroma Chatterjee, Clive P. Morgan, Jocelyn F. Krey, Connor Benson, Jennifer Goldsmith, Michael Bateschell, Anthony J. Ricci, Peter G. Barr-Gillespie

J Cell Sci. 2023 May 15; 136(10): jcs261100. Published online 2023 May 25. doi: 10.1242/jcs.261100

PMCID:: PMC10234109

Abstract Article

Select item 102199825.

Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2

Matthew J. Thompson, Caryl A. Young, Vidhya Munnamalai, David M. Umulis

Sci Rep. 2023; 13: 8567. Published online 2023 May 26. doi: 10.1038/s41598-023-34725-4

PMCID:: PMC10219982

Abstract Article PDF–3.1M

Select item 98701346.

In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear

Chiara Chiereghin, Michela Robusto, Morag A. Lewis, Susana Caetano, Valentina Massa, Pierangela Castorina, Umberto Ambrosetti, Karen P. Steel, Stefano Duga, Rosanna Asselta, Giulia Soldà

PLoS One. 2023; 18(1): e0273586. Published online 2023 Jan 23. doi: 10.1371/journal.pone.0273586

PMCID:: PMC9870134

Abstract Article PDF–3.5M

Select item 98442477.

Development and transdifferentiation into inner hair cells require Tbx2

Zhenghong Bi, Xiang Li, Minhui Ren, Yunpeng Gu, Tong Zhu, Shuting Li, Guangqin Wang, Suhong Sun, Yuwei Sun, Zhiyong Liu

Natl Sci Rev. 2022 Dec; 9(12): nwac156. Published online 2022 Aug 9. doi: 10.1093/nsr/nwac156

PMCID:: PMC9844247

Abstract Article PDF–1.9M

Select item 98129108.

Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A

Homero L. Cantu-Guerra, Michael R. Papazian, Anna L. Gorsky, Nathalie S. Alekos, Adam Caccavano, Nare Karagulyan, Jakob Neef, Stefano Vicini, Tobias Moser, Thomas M. Coate

Dev Dyn. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Dev Dyn. 2023 Jan; 252(1): 124–144. Published online 2022 Nov 4. doi: 10.1002/dvdy.548

PMCID:: PMC9812910

Abstract Article PDF–5.3M

Select item 97906759.

PRDM16 expression and function in mammalian cochlear development

Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork

Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480

PMCID:: PMC9790675

Abstract Article PDF–17M

Select item 960386010.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 937173011.

Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development

Zhengnan Luo, Yi Du, Shuting Li, He Zhang, Muya Shu, Di Zhang, Shunji He, Guangqin Wang, Falong Lu, Zhiyong Liu

Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2119850119. Published online 2022 Aug 4. doi: 10.1073/pnas.2119850119

PMCID:: PMC9371730

Abstract Article PDF–3.5M

Select item 928636912.

Targeted deletion of Atoh8 results in severe hearing loss in mice

Qi Tang, Meng‐Yao Xie, Yong‐Li Zhang, Ruo‐Yan Xue, Xiao‐Hui Zhu, Hua Yang

Genesis. 2021 Sep; 59(9): e23442. Published online 2021 Aug 17. doi: 10.1002/dvg.23442

PMCID:: PMC9286369

Abstract Article PDF–9.0M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003