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Select item 109802791.

Extra centrosomes delay DNA damage–driven tumorigenesis

Vincent Z. Braun, Gerlinde Karbon, Fabian Schuler, Marina A. Schapfl, Johannes G. Weiss, Paul Y. Petermann, Diana C.J. Spierings, Andrea E. Tijhuis, Floris Foijer, Verena Labi, Andreas Villunger

Sci Adv. 2024 Mar 29; 10(13): eadk0564. Published online 2024 Mar 29. doi: 10.1126/sciadv.adk0564

PMCID:: PMC10980279

Abstract Article PDF–5.0M

Select item 95479472.

PIDDosome-SCAP crosstalk controls high fructose diet dependent transition from simple steatosis to steatohepatitis

Ju Youn Kim, Lily Q. Wang, Valentina C. Sladky, Tae Gyu Oh, Junlai Liu, Kaitlyn Trinh, Felix Eichin, Michael Downes, Mojgan Hosseini, Etienne D. Jacotot, Ronald M. Evans, Andreas Villunger, Michael Karin

Cell Metab. Author manuscript; available in PMC 2023 Oct 4.

Published in final edited form as: Cell Metab. 2022 Oct 4; 34(10): 1548–1560.e6. Published online 2022 Aug 29. doi: 10.1016/j.cmet.2022.08.005

PMCID:: PMC9547947

Abstract Article PDF–3.3M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159914.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 67583545.

Upregulation of the Fas Receptor Death-Inducing Signaling Complex after Traumatic Brain Injury in Mice and Humans

Jianhua Qiu, Michael J. Whalen, Pedro Lowenstein, Gary Fiskum, Brenda Fahy, Ribal Darwish, Bizhan Aarabi, Junying Yuan, Michael A. Moskowitz

J Neurosci. 2002 May 1; 22(9): 3504–3511. doi: 10.1523/JNEUROSCI.22-09-03504.2002

PMCID:: PMC6758354

Abstract Article PDF–445K

Select item 64956966.

Overexpression of Raidd cDNA inhibits differentiation of mouse preadipocytes

R. Felmer, S. Horvat, M. Clinton, A. J. Clark

Cell Prolif. 2003 Feb; 36(1): 45–54. Published online 2003 Jan 28. doi: 10.1046/j.1365-2184.2003.00253.x

PMCID:: PMC6495696

Abstract Article PDF–191K

Select item 54610157.

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus

Kiyohiro Ando, Melissa J. Parsons, Richa B. Shah, Chloé I. Charendoff, Sheré L. Paris, Peter H. Liu, Sara R. Fassio, Brittany A. Rohrman, Ruth Thompson, Andrew Oberst, Samuel Sidi, Lisa Bouchier-Hayes

J Cell Biol. 2017 Jun 5; 216(6): 1795–1810. doi: 10.1083/jcb.201608095

PMCID:: PMC5461015

Abstract Article PDF–2.8M

Select item 50979458.

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant

Nataliya Di Donato, Ying Y. Jean, A. Murat Maga, Briana D. Krewson, Alison B. Shupp, Maria I. Avrutsky, Achira Roy, Sarah Collins, Carissa Olds, Rebecca A. Willert, Agnieszka M. Czaja, Rachel Johnson, Jessi A. Stover, Steven Gottlieb, Deborah Bartholdi, Anita Rauch, Amy Goldstein, Victoria Boyd-Kyle, Kimberly A. Aldinger, Ghayda M. Mirzaa, Anke Nissen, Karlla W. Brigatti, Erik G. Puffenberger, Kathleen J. Millen, Kevin A. Strauss, William B. Dobyns, Carol M. Troy, Robert N. Jinks

Am J Hum Genet. 2016 Nov 3; 99(5): 1117–1129. Published online 2016 Oct 20. doi: 10.1016/j.ajhg.2016.09.010

PMCID:: PMC5097945

Abstract Article PDF–1.3M

Select item 46483279.

The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd

L Peintner, L Dorstyn, S Kumar, T Aneichyk, A Villunger, C Manzl

Cell Death Differ. 2015 Nov; 22(11): 1803–1811. Published online 2015 Apr 10. doi: 10.1038/cdd.2015.31

PMCID:: PMC4648327

Abstract Article PDF–1.8M

Select item 421292810.

Regulation of CRADD-caspase 2 cascade by histone deacetylase 1 in gastric cancer

Qi Shen, Wanfen Tang, Jie Sun, Lifeng Feng, Hongchuan Jin, Xian Wang

Am J Transl Res. 2014; 6(5): 538–547. Published online 2014 Oct 11.

PMCID:: PMC4212928

Abstract Article PDF–955K

Select item 413921411.

The Adaptor CRADD/RAIDD Controls Activation of Endothelial Cells by Proinflammatory Stimuli

Huan Qiao, Yan Liu, Ruth A. Veach, Lukasz Wylezinski, Jacek Hawiger

J Biol Chem. 2014 Aug 8; 289(32): 21973–21983. Published online 2014 Jun 23. doi: 10.1074/jbc.M114.588723

PMCID:: PMC4139214

Abstract Article PDF–2.1M

Select item 390545312.

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death

Ying Y. Jean, Elena M. Ribe, Maria Elena Pero, Marina Moskalenko, Zarah Iqbal, Lianna J. Marks, Lloyd A. Greene, Carol M. Troy

Biochem J. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Biochem J. 2013 Oct 1; 455(1): 15–25. doi: 10.1042/BJ20130556

PMCID:: PMC3905453

Abstract Article PDF–2.7M

Select item 336543813.

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

Elena M. Ribe, Ying Y. Jean, Rebecca L. Goldstein, Claudia Manzl, Leonidas Stefanis, Andreas Villunger, Carol M. Troy

Biochem J. 2012 Jun 15; 444(Pt 3): 591–599. Prepublished online 2012 Apr 19. Published online 2012 May 29. doi: 10.1042/BJ20111588

PMCID:: PMC3365438

Abstract Article PDF–843K

Select item 329414814.

The “Death” Adaptor CRADD/RAIDD Targets BCL10 and Suppresses Agonist-Induced Cytokine Expression in T Lymphocytes

Qing Lin, Yan Liu, Daniel J. Moore, Sydney K. Elizer, Ruth A. Veach, Jacek Hawiger, H. Earl Ruley

J Immunol. Author manuscript; available in PMC 2013 Mar 15.

Published in final edited form as: J Immunol. 2012 Mar 15; 188(6): 2493–2497. Published online 2012 Feb 8. doi: 10.4049/jimmunol.1101502

PMCID:: PMC3294148

Abstract Article PDF–1.9M

Select item 326015315.

Genetic Mapping and Exome Sequencing Identify Variants Associated with Five Novel Diseases

Erik G. Puffenberger, Robert N. Jinks, Carrie Sougnez, Kristian Cibulskis, Rebecca A. Willert, Nathan P. Achilly, Ryan P. Cassidy, Christopher J. Fiorentini, Kory F. Heiken, Johnny J. Lawrence, Molly H. Mahoney, Christopher J. Miller, Devika T. Nair, Kristin A. Politi, Kimberly N. Worcester, Roni A. Setton, Rosa DiPiazza, Eric A. Sherman, James T. Eastman, Christopher Francklyn, Susan Robey-Bond, Nicholas L. Rider, Stacey Gabriel, D. Holmes Morton, Kevin A. Strauss

PLoS One. 2012; 7(1): e28936. Published online 2012 Jan 17. doi: 10.1371/journal.pone.0028936

PMCID:: PMC3260153

Abstract Article PDF–6.2M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312173517.

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang, Catalin Barbacioru, Ellen Nordman, Siqin Bao, Caroline Lee, Xiaohui Wang, Brian B. Tuch, Edith Heard, Kaiqin Lao, M. Azim Surani

PLoS One. 2011; 6(6): e21208. Published online 2011 Jun 23. doi: 10.1371/journal.pone.0021208

PMCID:: PMC3121735

Abstract Article PDF–1.0M

Select item 270037418.

Caspase-2 activation in the absence of PIDDosome formation

Claudia Manzl, Gerhard Krumschnabel, Florian Bock, Benedicte Sohm, Verena Labi, Florian Baumgartner, Emmanuelle Logette, Jürg Tschopp, Andreas Villunger

J Cell Biol. 2009 Apr 20; 185(2): 291–303. doi: 10.1083/jcb.200811105

PMCID:: PMC2700374

Abstract Article PDF–3.5M

Select item 255627019.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 163530920.

Mutagenesis of diploid mammalian genes by gene entrapment

Qing Lin, Sarah L. Donahue, Tracy Moore-Jarrett, Shang Cao, Anna B. Osipovich, H. Earl Ruley

Nucleic Acids Res. 2006 Nov; 34(20): e139. Published online 2006 Oct 24. doi: 10.1093/nar/gkl728

PMCID:: PMC1635309

Abstract Article PDF–347K

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