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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103540662.

Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer

Sebastian Huth, Laura Huth, Ruth Heise, Yvonne Marquardt, Linda Lopopolo, Marta Piecychna, Peter Boor, Günter Fingerle-Rowson, Aphrodite Kapurniotu, Amir S. Yazdi, Richard Bucala, Jürgen Bernhagen, Jens Malte Baron

Sci Rep. 2023; 13: 11611. Published online 2023 Jul 18. doi: 10.1038/s41598-023-38748-9

PMCID:: PMC10354066

Abstract Article PDF–3.3M

Select item 97149923.

“Near Cure” treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct

Arthur A Vandenbark, Roberto Meza-Romero, Jack Wiedrick, Grant Gerstner, Hilary Seifert, Gail Kent, Marta Piechycna, Gil Benedek, Richard Bucala, Halina Offner

Cell Immunol. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Cell Immunol. 2022 Aug; 378: 104561. Published online 2022 Jun 11. doi: 10.1016/j.cellimm.2022.104561

PMCID:: PMC9714992

Abstract Article PDF–2.9M

Select item 96038604.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 86316025.

MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model

Pathricia Veronica Tilstam, Wibke Schulte, Thomas Holowka, Bong-Sung Kim, Jessica Nouws, Maor Sauler, Marta Piecychna, Georgios Pantouris, Elias Lolis, Lin Leng, Jürgen Bernhagen, Günter Fingerle-Rowson, Richard Bucala

J Clin Invest. 2021 Dec 1; 131(23): e127171. Published online 2021 Dec 1. doi: 10.1172/JCI127171

PMCID:: PMC8631602

Abstract Article PDF–4.8M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 67779118.

Cardiomyocyte d-dopachrome tautomerase protects against heart failure

Yina Ma, Kevin N. Su, Daniel Pfau, Veena S. Rao, Xiaohong Wu, Xiaoyue Hu, Lin Leng, Xin Du, Marta Piecychna, Kenneth Bedi, Stuart G. Campbell, Anne Eichmann, Jeffrey M. Testani, Kenneth B. Margulies, Richard Bucala, Lawrence H. Young

JCI Insight. 2019 Sep 5; 4(17): e128900. Published online 2019 Sep 5. doi: 10.1172/jci.insight.128900

PMCID:: PMC6777911

Abstract Article PDF–7.4M

Select item 61483059.

MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms

Akinobu Ochi, Dong Chen, Wibke Schulte, Lin Leng, Nickolas Moeckel, Marta Piecychna, Luisa Averdunk, Christian Stoppe, Richard Bucala, Gilbert Moeckel

Am J Physiol Renal Physiol. 2017 Sep 1; 313(3): F767–F780. Published online 2017 May 24. doi: 10.1152/ajprenal.00683.2016

PMCID:: PMC6148305

Abstract Article

Select item 601029210.

TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells

Lara Valiño-Rivas, Leticia Cuarental, Osvaldo Grana, Richard Bucala, Lin Leng, Ana Sanz, Gonzalo Gomez, Alberto Ortiz, Maria Dolores Sanchez-Niño

PLoS One. 2018; 13(6): e0199391. Published online 2018 Jun 20. doi: 10.1371/journal.pone.0199391

PMCID:: PMC6010292

Abstract Article PDF–13M

Select item 420032811.

Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment

Deepa Rajasekaran, Swen Zierow, Mansoor Syed, Richard Bucala, Vineet Bhandari, Elias J. Lolis

FASEB J. 2014 Nov; 28(11): 4961–4971. doi: 10.1096/fj.14-256636

PMCID:: PMC4200328

Abstract Article

Select item 410952412.

The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury

Dake Qi, Kwame Atsina, Lintao Qu, Xiaoyue Hu, Xiaohong Wu, Bin Xu, Marta Piecychna, Lin Leng, Günter Fingerle-Rowson, Jiasheng Zhang, Richard Bucala, Lawrence H. Young

J Clin Invest. 2014 Aug 1; 124(8): 3540–3550. Published online 2014 Jul 1. doi: 10.1172/JCI73061

PMCID:: PMC4109524

Abstract Article PDF–3.7M

Select item 396495513.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 318949214.

Three-dimensional visualisation of testis cord morphogenesis, a novel tubulogenic mechanism in development

Alexander N. Combes, Emmanuelle Lesieur, Vincent R. Harley, Andrew H. Sinclair, Melissa H. Little, Dagmar Wilhelm, Peter Koopman

Dev Dyn. Author manuscript; available in PMC 2011 Oct 9.

Published in final edited form as: Dev Dyn. 2009 May; 238(5): 1033–1041. doi: 10.1002/dvdy.21925

PMCID:: PMC3189492

Abstract Article PDF–2.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316158216.

The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)

Melanie Merk, Swen Zierow, Lin Leng, Rituparna Das, Xin Du, Wibke Schulte, Juan Fan, Hongqi Lue, Yibang Chen, Huabao Xiong, Frederic Chagnon, Jürgen Bernhagen, Elias Lolis, Gil Mor, Olivier Lesur, Richard Bucala

Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34): E577–E585. Published online 2011 Aug 4. doi: 10.1073/pnas.1102941108

PMCID:: PMC3161582

Abstract Article PDF–1.3M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582