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Items: 1 to 20 of 123

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Integrin-linked kinase expression in myeloid cells promotes colon tumorigenesis
Afsar U. Ahmed, Saleh Almasabi, Ron Firestein, Bryan R.G. Williams
Front Immunol. 2023; 14: 1270194. Published online 2023 Nov 21. doi: 10.3389/fimmu.2023.1270194
PMCID:
PMC10710162
AbstractArticlePDF–6.2M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation
Sofía Campillo, Lourdes Bohorquez, Elena Gutiérrez-Calabrés, Diego García-Ayuso, Verónica Miguel, Mercedes Griera, Yolanda Calle, Sergio de Frutos, Manuel Rodríguez-Puyol, Diego Rodríguez-Puyol, Laura Calleros
Exp Mol Med. 2022 Mar; 54(3): 226–238. Published online 2022 Mar 4. doi: 10.1038/s12276-022-00738-8
PMCID:
PMC8980039
AbstractArticlePDF–4.0M
5.
Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT
Emann M. Rabie, Sherry X. Zhang, Connor E. Dunn, Celeste M. Nelson
Mol Biol Cell. 2021 Aug 19; 32(18): 1664–1676. doi: 10.1091/mbc.E21-02-0072
PMCID:
PMC8684726
AbstractArticlePDF–6.5M
6.
Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1
Ayse Nihan Kilinc, Siyang Han, Lena A. Barrett, Niroshan Anandasivam, Celeste M. Nelson
Mol Biol Cell. 2021 Mar 1; 32(5): 402–412. doi: 10.1091/mbc.E20-02-0092
PMCID:
PMC8098849
AbstractArticlePDF–2.8M
7.
Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice
Nada Bulus, Kyle L. Brown, Glenda Mernaugh, Anika Böttcher, Xinyu Dong, Charles R. Sanders, Ambra Pozzi, Reinhard Fässler, Roy Zent
J Biol Chem. 2021 Jan-Jun; 296: 100361. Published online 2021 Feb 2. doi: 10.1016/j.jbc.2021.100361
PMCID:
PMC7949147
ArticlePDF–4.8M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Integrin-linked kinase regulates melanosome trafficking and melanin transfer in melanocytes
Melissa Crawford, Nancy Liu, Elahe Mahdipour, Kevin Barr, Bryan Heit, Lina Dagnino
Mol Biol Cell. 2020 Apr 1; 31(8): 768–781. doi: 10.1091/mbc.E19-09-0510
PMCID:
PMC7185957
AbstractArticlePDF–3.7M
10.
Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy
Hongryeol Park, Hiroyuki Yamamoto, Lucas Mohn, Lea Ambühl, Kenichi Kanai, Inga Schmidt, Kee-Pyo Kim, Alessia Fraccaroli, Silke Feil, Harald J. Junge, Eloi Montanez, Wolfgang Berger, Ralf H. Adams
Nat Commun. 2019; 10: 5243. Published online 2019 Nov 20. doi: 10.1038/s41467-019-13220-3
PMCID:
PMC6868140
AbstractArticlePDF–10M
11.
Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis
Ming Huang, Shuai Zhu, Huihui Huang, Jinzhao He, Kenji Tsuji, William W. Jin, Dongping Xie, Onju Ham, Diane E. Capen, Weining Lu, Teodor G. Păunescu, Baoxue Yang, Hua A. Jenny Lu
J Am Soc Nephrol. 2019 Nov; 30(11): 2073–2090. Published online 2019 Oct 25. doi: 10.1681/ASN.2018111162
PMCID:
PMC6830785
AbstractArticle
12.
A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice
Chaehyun Yook, Kyungdeok Kim, Doyoun Kim, Hyojin Kang, Sun-Gyun Kim, Eunjoon Kim, Soo Young Kim
Front Mol Neurosci. 2019; 12: 241. Published online 2019 Oct 9. doi: 10.3389/fnmol.2019.00241
PMCID:
PMC6797848
AbstractArticlePDF–6.4M
13.
Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner
Elijah Trefts, Curtis C. Hughey, Louise Lantier, Dan S. Lark, Kelli L. Boyd, Ambra Pozzi, Roy Zent, David H. Wasserman
Am J Physiol Endocrinol Metab. 2019 Jun 1; 316(6): E1118–E1135. Published online 2019 Mar 5. doi: 10.1152/ajpendo.00496.2018
PMCID:
PMC6732653
AbstractArticle
14.
Integrin-Linked Kinase Regulates Process Extension in Oligodendrocytes via Control of Actin Cytoskeletal Dynamics
Ryan W. O'Meara, John-Paul Michalski, Carrie Anderson, Kunal Bhanot, Peter Rippstein, Rashmi Kothary
J Neurosci. 2013 Jun 5; 33(23): 9781–9793. doi: 10.1523/JNEUROSCI.5582-12.2013
PMCID:
PMC6619710
AbstractArticlePDF–2.7M
15.
Dissecting Integrin-Dependent Regulation of Neural Stem Cell Proliferation in the Adult Brain
Cristina Porcheri, Ueli Suter, Sebastian Jessberger
J Neurosci. 2014 Apr 9; 34(15): 5222–5232. doi: 10.1523/JNEUROSCI.4928-13.2014
PMCID:
PMC6608998
AbstractArticlePDF–3.5M
16.
Foxc2 is essential for podocyte function
Daniel Nilsson, Mikael Heglind, Zahra Arani, Sven Enerbäck
Physiol Rep. 2019 May; 7(9): e14083. Published online 2019 May 6. doi: 10.14814/phy2.14083
PMCID:
PMC6503019
AbstractArticlePDF–15M
17.
Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling
Thomas Volckaert, Tingting Yuan, Jie Yuan, Eistine Boateng, Seantel Hopkins, Jin-San Zhang, Victor J. Thannickal, Reinhard Fässler, Stijn P. De Langhe
Development. 2019 Jan 15; 146(2): dev166454. Published online 2019 Jan 16. doi: 10.1242/dev.166454
PMCID:
PMC6361136
AbstractArticle
18.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
19.
TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators
Julian Nüchel, Sushmita Ghatak, Alexandra V. Zuk, Anja Illerhaus, Matthias Mörgelin, Katrin Schönborn, Katrin Blumbach, Sara A. Wickström, Thomas Krieg, Gerhard Sengle, Markus Plomann, Beate Eckes
Autophagy. 2018; 14(3): 465–486. Published online 2018 Mar 11. doi: 10.1080/15548627.2017.1422850
PMCID:
PMC5915026
AbstractArticlePDF–2.2M
20.
Fgf10-Hippo epithelial mesenchymal crosstalk maintains and recruits lung basal stem cells
Thomas Volckaert, Tingting Yuan, Cho-Ming Chao, Harold Bell, Alina Sitaula, Luisa Szimmtenings, Elie El Agha, Diptiman Chanda, Susan Majka, Saverio Bellusci, Victor J. Thannickal, Reinhard Fässler, Stijn P. De Langhe
Dev Cell. Author manuscript; available in PMC 2018 Oct 9.
Published in final edited form as: Dev Cell. 2017 Oct 9; 43(1): 48–59.e5. doi: 10.1016/j.devcel.2017.09.003
PMCID:
PMC5679744
AbstractArticlePDF–3.4M

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