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Items: 1 to 20 of 30

1.
Cryo‐EM structures of perforin‐2 in isolation and assembled on a membrane suggest a mechanism for pore formation
Xiulian Yu, Tao Ni, George Munson, Peijun Zhang, Robert J C Gilbert
EMBO J. 2022 Dec; 41(23): e111857. Published online 2022 Oct 17. doi: 10.15252/embj.2022111857
PMCID:
PMC9713709
AbstractArticlePDF–3.9M
2.
Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation
Salimeh Ebrahimnezhaddarzi, Catherina H Bird, Cody C Allison, Daniel E Tuipulotu, Xenia Kostoulias, Christophe Macri, Michael D Stutz, Gilu Abraham, Dion Kaiserman, Siew Siew Pang, Si Ming Man, Justine D Mintern, Thomas Naderer, Anton Y Peleg, Marc Pellegrini, James C Whisstock, Phillip I Bird
Immunol Cell Biol. 2022 Aug; 100(7): 529–546. Published online 2022 May 12. doi: 10.1111/imcb.12554
PMCID:
PMC9545170
AbstractArticlePDF–1.3M
3.
Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to perforin-2 suppression
Irena Pastar, Andrew P. Sawaya, Jelena Marjanovic, Jamie L. Burgess, Natasa Strbo, Katelyn E. Rivas, Tongyu C. Wikramanayake, Cheyanne R. Head, Rivka C. Stone, Ivan Jozic, Olivera Stojadinovic, Eran Y. Kornfeld, Robert S. Kirsner, Hadar Lev-Tov, Marjana Tomic-Canic
J Clin Invest. 2021 Dec 15; 131(24): e133727. Published online 2021 Dec 15. doi: 10.1172/JCI133727
PMCID:
PMC8670843
AbstractArticlePDF–2.1M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
Cellular context of IL-33 expression dictates impact on anti-helminth immunity
Li-Yin Hung, Yukinori Tanaka, Karl Herbine, Christopher Pastore, Brenal Singh, Annabel Ferguson, Nisha Vora, Bonnie Douglas, Kelly Zullo, Ed Behrens, Tiffany Li Hui Tan, Michael A. Kohanski, Paul Bryce, Cailu Lin, Taku Kambayashi, Danielle R. Reed, Breann L. Brown, Noam A. Cohen, De’Broski R. Herbert
Sci Immunol. Author manuscript; available in PMC 2021 Jul 5.
Published in final edited form as: Sci Immunol. 2020 Nov 13; 5(53): eabc6259. doi: 10.1126/sciimmunol.abc6259
PMCID:
PMC8257082
AbstractArticlePDF–1.2M
6.
Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells
Pablo Rodríguez-Silvestre, Marco Laub, Patrycja A. Krawczyk, Alexandra K. Davies, Julia P. Schessner, Reejuana Parveen, Benjamin J. Tuck, William A. McEwan, Georg H.H. Borner, Patrycja Kozik
Science. Author manuscript; available in PMC 2023 Jul 19.
Published in final edited form as: Science. 2023 Jun 23; 380(6651): 1258–1265. Published online 2023 Jun 22. doi: 10.1126/science.adg8802
PMCID:
PMC7614779
AbstractArticlePDF–1.8M
7.
Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS
Ching Serena Kao, Rebekah van Bruggen, Jihye Rachel Kim, Xiao Xiao Lily Chen, Cadia Chan, Jooyun Lee, Woo In Cho, Melody Zhao, Claudia Arndt, Katarina Maksimovic, Mashiat Khan, Qiumin Tan, Michael D. Wilson, Jeehye Park
Nat Commun. 2020; 11: 5304. Published online 2020 Oct 20. doi: 10.1038/s41467-020-18949-w
PMCID:
PMC7576598
AbstractArticlePDF–4.2M
8.
Impaired B Cell Function in Mice Lacking Perforin-2
Daniela Frasca, Alain Diaz, Maria Romero, Thomas Vazquez, Natasa Strbo, Laura Romero, Ryan M. McCormack, Eckhard R. Podack, Bonnie B. Blomberg
Front Immunol. 2020; 11: 328. Published online 2020 Feb 27. doi: 10.3389/fimmu.2020.00328
PMCID:
PMC7057857
AbstractArticlePDF–1.0M
9.
Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity
Tao Ni, Fang Jiao, Xiulian Yu, Saša Aden, Lucy Ginger, Sophie I. Williams, Fangfang Bai, Vojtěch Pražák, Dimple Karia, Phillip Stansfeld, Peijun Zhang, George Munson, Gregor Anderluh, Simon Scheuring, Robert J. C. Gilbert
Sci Adv. 2020 Jan; 6(5): eaax8286. Published online 2020 Jan 29. doi: 10.1126/sciadv.aax8286
PMCID:
PMC6989145
AbstractArticlePDF–5.1M
10.
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Science. Author manuscript; available in PMC 2019 Jul 24.
Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030
PMCID:
PMC6655551
AbstractArticlePDF–1020K
11.
Single-cell transcriptomic analysis of mouse neocortical development
Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9
PMCID:
PMC6329831
AbstractArticlePDF–3.6M
12.
Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets
Fangfang Bai, Ryan M. McCormack, Suzanne Hower, Gregory V. Plano, Mathias G. Lichtenheld, George P. Munson
J Immunol. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: J Immunol. 2018 Nov 1; 201(9): 2710–2720. Published online 2018 Sep 24. doi: 10.4049/jimmunol.1800365
PMCID:
PMC6200583
AbstractArticlePDF–1.0M
13.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
14.
Molecular characterization of the genital organizer: Gene expression profile of the mouse urethral plate epithelium
Brooke A. Armfield, Ashley W. Seifert, Zhengui Zheng, Emily M. Merton, Jason R. Rock, Maria-Cecilia Lopez, Henry V. Baker, Martin J. Cohn
J Urol. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: J Urol. 2016 Oct; 196(4): 1295–1302. Published online 2016 May 9. doi: 10.1016/j.juro.2016.04.091
PMCID:
PMC5293367
AbstractArticlePDF–1.4M
15.
Gene expression analysis of the embryonic subplate
Franziska M. Oeschger, Wei-Zhi Wang, Sheena Lee, Fernando García-Moreno, André M. Goffinet, Mariona Arbones, Sonia Rakic, Zoltán Molnár
Cereb Cortex. Author manuscript; available in PMC 2016 Aug 3.
Published in final edited form as: Cereb Cortex. 2012 Jun; 22(6): 1343–1359. Published online 2011 Aug 22. doi: 10.1093/cercor/bhr197
PMCID:
PMC4972418
AbstractArticlePDF–7.1M
16.
Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA
Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu
BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y
PMCID:
PMC4970213
AbstractArticlePDF–2.5M
17.
Perforin-2 Protects Host Cells and Mice by Restricting the Vacuole to Cytosol Transitioning of a Bacterial Pathogen
Ryan McCormack, Wael Bahnan, Niraj Shrestha, Justin Boucher, Marcella Barreto, Carlos M. Barrera, Edward A. Dauer, Nancy E. Freitag, Wasif N. Khan, Eckhard R. Podack, Kurt Schesser
Infect Immun. 2016 Apr; 84(4): 1083–1091. Prepublished online 2016 Feb 1. Published online 2016 Mar 24. doi: 10.1128/IAI.01434-15
PMCID:
PMC4807494
AbstractArticlePDF–1.1M
18.
Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria
Ryan M McCormack, Lesley R de Armas, Motoaki Shiratsuchi, Desiree G Fiorentino, Melissa L Olsson, Mathias G Lichtenheld, Alejo Morales, Kirill Lyapichev, Louis E Gonzalez, Natasa Strbo, Neelima Sukumar, Olivera Stojadinovic, Gregory V Plano, George P Munson, Marjana Tomic-Canic, Robert S Kirsner, David G Russell, Eckhard R Podack
eLife. 2015; 4: e06508. Published online 2015 Sep 24. doi: 10.7554/eLife.06508
PMCID:
PMC4626811
AbstractArticlePDF–4.3M
19.
Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2
Ryan M McCormack, Kirill Lyapichev, Melissa L Olsson, Eckhard R Podack, George P Munson
eLife. 2015; 4: e06505. Published online 2015 Sep 29. doi: 10.7554/eLife.06505
PMCID:
PMC4626573
AbstractArticlePDF–4.5M
20.
Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis
Kevin X. Liu, Benjamin Edwards, Sheena Lee, Mattéa J. Finelli, Ben Davies, Kay E. Davies, Peter L. Oliver
Brain. 2015 May; 138(5): 1167–1181. Published online 2015 Mar 9. doi: 10.1093/brain/awv039
PMCID:
PMC4407188
AbstractArticlePDF–1.6M

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