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Select item 108989401.

TNF-α protects from exacerbated myocarditis and cardiac death by suppressing expansion of activated heart-reactive CD4⁺ T cells

Filip Rolski, Karolina Tkacz, Kazimierz Węglarczyk, Grzegorz Kwiatkowski, Paweł Pelczar, Agnieszka Jaźwa-Kusior, Anna Bar, Gabriela M Kuster, Stefan Chłopicki, Maciej Siedlar, Gabriela Kania, Przemysław Błyszczuk

Cardiovasc Res. 2024 Jan; 120(1): 82–94. Published online 2023 Oct 25. doi: 10.1093/cvr/cvad158

PMCID:: PMC10898940

Abstract Article PDF–1.3M

Select item 108842882.

TNFα: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease

Sophie L. Gibbings, Kelsey C. Haist, Elizabeth F. Redente, Peter M. Henson, Donna L. Bratton

Front Immunol. 2024; 15: 1354836. Published online 2024 Feb 9. doi: 10.3389/fimmu.2024.1354836

PMCID:: PMC10884288

Abstract Article PDF–4.2M

Select item 108336063.

TNF-α from the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy

Yi Wen, Xiaohan Lu, Jamie R. Privratsky, Jiafa Ren, Saba Ali, Bo Yang, Nathan P. Rudemiller, Jiandong Zhang, Sergei A. Nedospasov, Steven D. Crowley

Kidney360. 2024 Jan; 5(1): 44–56. Published online 2023 Nov 21. doi: 10.34067/KID.0000000000000314

PMCID:: PMC10833606

Abstract Article PDF–1.3M

Select item 108168994.

Knockout of the Tnfa Gene Decreases Influenza Virus-Induced Histological Reactions in Laboratory Mice

Darya A. Savenkova, Andrey S. Gudymo, Alexey N. Korablev, Oleg S. Taranov, Darya V. Bazovkina, Nataliya V. Danilchenko, Olga N. Perfilyeva, Elena K. Ivleva, Anastasiya A. Moiseeva, Yulia A. Bulanovich, Elena V. Roshchina, Irina A. Serova, Nariman R. Battulin, Elizabeth A. Kulikova, Dmitry V. Yudkin

Int J Mol Sci. 2024 Jan; 25(2): 1156. Published online 2024 Jan 18. doi: 10.3390/ijms25021156

PMCID:: PMC10816899

Abstract Article PDF–1.0M

Select item 107877915.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 107775726.

Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice

Xue Bai, Bing Wang, Yiduo Cui, Siqi Tian, Yi Zhang, Linhao You, Yan-Zhong Chang, Guofen Gao

J Neuroinflammation. 2024; 21: 15. Published online 2024 Jan 9. doi: 10.1186/s12974-023-03008-0

PMCID:: PMC10777572

Abstract Article PDF–8.2M

Select item 106660357.

Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALS

Seiji Watanabe, Yuri Murata, Yasuyoshi Oka, Kotaro Oiwa, Mai Horiuchi, Yohei Iguchi, Okiru Komine, Akira Sobue, Masahisa Katsuno, Tomoo Ogi, Koji Yamanaka

Proc Natl Acad Sci U S A. 2023 Nov 21; 120(47): e2315347120. Published online 2023 Nov 15. doi: 10.1073/pnas.2315347120

PMCID:: PMC10666035

Abstract Article PDF–8.9M

Select item 106465518.

cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars M Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas, Domagoj Vucic, John Silke, Manolis Pasparakis, Hamid Kashkar

EMBO J. 2023 Nov; 42(22): e113614. Published online 2023 Oct 4. doi: 10.15252/embj.2023113614

PMCID:: PMC10646551

Abstract Article PDF–3.3M

Select item 106376999.

The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

Hui Zhao, Ronald J. Wong, David K. Stevenson

PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185

PMCID:: PMC10637699

Abstract Article PDF–3.6M

Select item 1062076810.

Infection and inflammation stimulate expansion of a CD74⁺ Paneth cell subset to regulate disease progression

Iyshwarya Balasubramanian, Sheila Bandyopadhyay, Juan Flores, Jared Bianchi‐Smak, Xiang Lin, Haoran Liu, Shengxiang Sun, Natasha B Golovchenko, Yue Liu, Dahui Wang, Radha Patel, Ivor Joseph, Panan Suntornsaratoon, Justin Vargas, Peter HR Green, Govind Bhagat, Stephen M Lagana, Wang Ying, Yi Zhang, Zhihan Wang, Wei Vivian Li, Sukhwinder Singh, Zhongren Zhou, George Kollias, Laura A Farr, Shannon N Moonah, Shiyan Yu, Zhi Wei, Edward M Bonder, Lanjing Zhang, Pawel R Kiela, Karen L Edelblum, Ronaldo Ferraris, Ta‐Chiang Liu, Nan Gao

EMBO J. 2023 Nov; 42(21): e113975. Published online 2023 Sep 18. doi: 10.15252/embj.2023113975

PMCID:: PMC10620768

Abstract Article PDF–9.7M

Select item 1061691611.

MiR-142-3p is a Critical Modulator of TNF-mediated Neuronal Toxicity in Multiple Sclerosis

Francesca De Vito, Sara Balletta, Silvia Caioli, Alessandra Musella, Livia Guadalupi, Valentina Vanni, Diego Fresegna, Mario Stampanoni Bassi, Luana Gilio, Krizia Sanna, Antonietta Gentile, Antonio Bruno, Ettore Dolcetti, Fabio Buttari, Luigi Pavone, Roberto Furlan, Annamaria Finardi, Emerald Perlas, Eran Hornstein, Diego Centonze, Georgia Mandolesi

Curr Neuropharmacol. 2023 Sep 25; 21(12): 2567–2582. Published online 2023 Sep 25. doi: 10.2174/1570159X21666230404103914

PMCID:: PMC10616916

Abstract Article PDF–6.1M

Select item 1057572812.

Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis

Efren A. Reyes, David Castillo-Azofeifa, Jérémie Rispal, Tomas Wald, Rachel K. Zwick, Brisa Palikuqi, Angela Mujukian, Shervin Rabizadeh, Alexander R. Gupta, James M. Gardner, Dario Boffelli, Zev J. Gartner, Ophir D. Klein

J Clin Invest. 2023 Oct 16; 133(20): e163591. Published online 2023 Oct 16. doi: 10.1172/JCI163591

PMCID:: PMC10575728

Abstract Article PDF–4.7M

Select item 1054730013.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 1054186314.

The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis

Abrar Ul Haq Khan, Alaa Kassim Ali, Bryan Marr, Donghyeon Jo, Simin Ahmadvand, Claire Fong-McMaster, Saeedah Musaed Almutairi, Lisheng Wang, Subash Sad, Mary-Ellen Harper, Seung-Hwan Lee

Cell Mol Immunol. 2023 Oct; 20(10): 1140–1155. Published online 2023 Aug 9. doi: 10.1038/s41423-023-01071-4

PMCID:: PMC10541863

Abstract Article PDF–3.6M

Select item 1049360015.

TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

Katharina Burger, Finn Jung, Anja Baumann, Annette Brandt, Raphaela Staltner, Victor Sánchez, Ina Bergheim

Redox Biol. 2023 Oct; 66: 102870. Published online 2023 Sep 1. doi: 10.1016/j.redox.2023.102870

PMCID:: PMC10493600

Abstract Article PDF–6.9M

Select item 1048789816.

TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb

Chunyu Cai, Qihui Luo, Lanlan Jia, Yu Xia, Xinting Lan, Xiaoli Wei, Shuai Shi, Yucong Liu, Yao Wang, Zongliang Xiong, Riyi Shi, Chao Huang, Zhengli Chen

Int J Mol Sci. 2023 Sep; 24(17): 13439. Published online 2023 Aug 30. doi: 10.3390/ijms241713439

PMCID:: PMC10487898

Abstract Article PDF–7.5M

Select item 1043991217.

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

Lien Verboom, Christopher J. Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi S. Ravichandran, Lars Vereecke, Geert van Loo

Cell Death Dis. 2023 Aug; 14(8): 534. Published online 2023 Aug 19. doi: 10.1038/s41419-023-06058-7

PMCID:: PMC10439912

Abstract Article PDF–3.7M

Select item 1041610318.

Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation

Han Meng, Youyi Zhao, Yuqian Li, Hong Fan, Xuyang Yi, Xinyu Meng, Pengfei Wang, Fanfan Fu, Shengxi Wu, Yazhou Wang

Front Cell Dev Biol. 2023; 11: 1229788. Published online 2023 Jul 27. doi: 10.3389/fcell.2023.1229788

PMCID:: PMC10416103

Abstract Article PDF–3.6M

Select item 1037817719.

Macrophage–endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa

Xingsheng Ren, Laura D. Manzanares, Enzo B. Piccolo, Jessica M. Urbanczyk, David P. Sullivan, Lenore K. Yalom, Triet M. Bui, Connor Lantz, Hinda Najem, Parambir S. Dulai, Amy B. Heimberger, Edward B. Thorp, Ronen Sumagin

J Clin Invest. 2023 Aug 1; 133(15): e170733. Published online 2023 Aug 1. doi: 10.1172/JCI170733

PMCID:: PMC10378177

Abstract Article PDF–16M

Select item 1022864220.

Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice

Rachel H. McMahan, Holly J. Hulsebus, Kevin M. Najarro, Lauren E. Giesy, Daniel N. Frank, Elizabeth J. Kovacs

Alcohol. Author manuscript; available in PMC 2023 May 30.

Published in final edited form as: Alcohol. 2023 Mar; 107: 136–143. Published online 2022 Sep 21. doi: 10.1016/j.alcohol.2022.08.011

PMCID:: PMC10228642

Abstract Article PDF–1.0M

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