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Select item 109404921.

Involvement of sodium–glucose cotransporter-1 activities in maintaining oscillatory Cl⁻ currents from mouse submandibular acinar cells

Misa Takeyasu, Katsuyuki Kozai, Makoto Sugita

J Comp Physiol B. 2024; 194(1): 21–32. Published online 2024 Feb 3. doi: 10.1007/s00360-024-01532-w

PMCID:: PMC10940492

Abstract Article PDF–1.2M

Select item 107180802.

Fgf8 promotes survival of nephron progenitors by regulating BAX/BAKmediated apoptosis.

Matthew J. Anderson, Salvia Misaghian, Nirmala Sharma, Alan O. Perantoni, Mark Lewandoski

Differentiation. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Differentiation. 2023 Mar-Apr; 130: 7–15. Published online 2022 Dec 6. doi: 10.1016/j.diff.2022.12.001

PMCID:: PMC10718080

Abstract Article PDF–1.9M

Select item 102919353.

Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection

F. Christopher Peritore-Galve, Izumi Kaji, Anna Smith, Lauren M. Walker, John A. Shupe, M. Kay Washington, Holly M. Scott Algood, Pradeep K. Dudeja, James R. Goldenring, D. Borden Lacy

Gut Microbes. 2023; 15(1): 2225841. Published online 2023 Jun 23. doi: 10.1080/19490976.2023.2225841

PMCID:: PMC10291935

Abstract Article PDF–8.4M

Select item 102437414.

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

Shira N. Johnston, Elizabeth S. Silagi, Vedavathi Madhu, Duc H. Nguyen, Irving M. Shapiro, Makarand V. Risbud

JCI Insight. 2023 Apr 24; 8(8): e164883. Published online 2023 Apr 24. doi: 10.1172/jci.insight.164883

PMCID:: PMC10243741

Abstract Article PDF–17M

Select item 91990175.

The sodium-glucose cotransporter isoform 1 (SGLT-1) is important for sperm energetics, motility, and fertility

September Numata, Jeff P McDermott, Gladis Sanchez, Amrita Mitra, Gustavo Blanco

Biol Reprod. 2022 Jun; 106(6): 1206–1217. Published online 2022 Apr 14. doi: 10.1093/biolre/ioac052

PMCID:: PMC9199017

Abstract Article PDF–1.3M

Select item 89026216.

Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine

Kimihiro Nishimura, Yukihiro Fujita, Shogo Ida, Tsuyoshi Yanagimachi, Natsuko Ohashi, Kiyoto Nishi, Atsushi Nishida, Yasumasa Iwasaki, Katsutaro Morino, Satoshi Ugi, Eiichiro Nishi, Akira Andoh, Hiroshi Maegawa

Mol Metab. 2022 May; 59: 101458. Published online 2022 Feb 19. doi: 10.1016/j.molmet.2022.101458

PMCID:: PMC8902621

Abstract Article PDF–4.5M

Select item 88650937.

HNF1α controls glucagon secretion in pancreatic α-cells through modulation of SGLT1

Yoshifumi Sato, Md Mostafizur Rahman, Masaki Haneda, Tomonori Tsuyama, Tomoya Mizumoto, Tatsuya Yoshizawa, Tadahiro Kitamura, Frank J. Gonzalez, Ken-ichi Yamamura, Kazuya Yamagata

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2022 Feb 23.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2020 Nov 1; 1866(11): 165898. Published online 2020 Jul 22. doi: 10.1016/j.bbadis.2020.165898

PMCID:: PMC8865093

Abstract Article PDF–1.8M

Select item 88636298.

Role of the macula densa sodium glucose cotransporter type 1-nitric oxide synthase 1-tubuloglomerular feedback pathway in diabetic hyperfiltration

Jie Zhang, Jing Cai, Yu Cui, Shan Jiang, Jin Wei, Young Chul Kim, Jenna Chan, Anish Thalakola, Thanh Le, Lan Xu, Lei Wang, Kun Jiang, Ximing Wang, Haibo Wang, Feng Cheng, Jacentha Buggs, Hermann Koepsell, Volker Vallon, Ruisheng Liu

Kidney Int. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Kidney Int. 2022 Mar; 101(3): 541–550. Published online 2021 Nov 26. doi: 10.1016/j.kint.2021.10.037

Correction in:: Kidney Int. 2022 Aug; 102(2): 448.

PMCID:: PMC8863629

Abstract Article PDF–1.8M

Select item 88527099.

Inhibition of SGLT1 Alleviates the Glycemic Variability-Induced Cardiac Fibrosis via Inhibition of Activation of Macrophage and Cardiac Fibroblasts

Weihua Wu, Qian Chai, Ziying Zhang

Mol Cell Biol. 2022 Feb; 42(2): e00282-21. Prepublished online 2021 Nov 29. Published online 2022 Feb 17. doi: 10.1128/mcb.00282-21

PMCID:: PMC8852709

Abstract Article PDF–4.1M

Select item 808280110.

New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans

Laura Ferté, Alice Marino, Sylvain Battault, Laurent Bultot, Anne Van Steenbergen, Anne Bol, Julien Cumps, Audrey Ginion, Hermann Koepsell, Laure Dumoutier, Louis Hue, Sandrine Horman, Luc Bertrand, Christophe Beauloye

Am J Physiol Heart Circ Physiol. 2021 Feb 1; 320(2): H838–H853. Published online 2021 Jan 8. doi: 10.1152/ajpheart.00736.2019

PMCID:: PMC8082801

Abstract Article

Select item 685054311.

Effects of insulin signaling on mouse taste cell proliferation

Shingo Takai, Yu Watanabe, Keisuke Sanematsu, Ryusuke Yoshida, Robert F. Margolskee, Peihua Jiang, Ikiru Atsuta, Kiyoshi Koyano, Yuzo Ninomiya, Noriatsu Shigemura

PLoS One. 2019; 14(11): e0225190. Published online 2019 Nov 12. doi: 10.1371/journal.pone.0225190

PMCID:: PMC6850543

Abstract Article PDF–3.2M

Select item 670439312.

Cardiac sodium-dependent glucose cotransporter 1 is a novel mediator of ischaemia/reperfusion injury

Zhao Li, Vineet Agrawal, Mohun Ramratnam, Ravi K Sharma, Stephen D’Auria, Abigail Sincoular, Margurite Jakubiak, Meredith L Music, William J Kutschke, Xueyin N Huang, Lindsey Gifford, Ferhaan Ahmad

Cardiovasc Res. 2019 Sep 1; 115(11): 1646–1658. Published online 2019 Feb 4. doi: 10.1093/cvr/cvz037

PMCID:: PMC6704393

Abstract Article PDF–1.1M

Select item 669272213.

Knockout of Na⁺-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration

Panai Song, Winnie Huang, Akira Onishi, Rohit Patel, Young Chul Kim, Charlotte van Ginkel, Yiling Fu, Brent Freeman, Hermann Koepsell, Scott Thomson, Ruisheng Liu, Volker Vallon

Am J Physiol Renal Physiol. 2019 Jul 1; 317(1): F207–F217. Published online 2019 May 15. doi: 10.1152/ajprenal.00120.2019

PMCID:: PMC6692722

Abstract Article

Select item 662059714.

Gene deletion of the Na⁺-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion

Josselin Nespoux, Rohit Patel, Kelly L. Hudkins, Winnie Huang, Brent Freeman, Young Chul Kim, Hermann Koepsell, Charles E. Alpers, Volker Vallon

Am J Physiol Renal Physiol. 2019 Jun 1; 316(6): F1201–F1210. Published online 2019 Apr 17. doi: 10.1152/ajprenal.00111.2019

PMCID:: PMC6620597

Abstract Article

Select item 656648715.

GI inflammation Increases Sodium-Glucose Cotransporter Sglt1

Jiyoung Park, In-Seung Lee, Kang-Hoon Kim, Yumi Kim, Eun-Jin An, Hyeung-Jin Jang

Int J Mol Sci. 2019 May; 20(10): 2537. Published online 2019 May 23. doi: 10.3390/ijms20102537

PMCID:: PMC6566487

Abstract Article PDF–2.4M

Select item 644235416.

Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia

Jie Zhang, Jin Wei, Shan Jiang, Lan Xu, Lei Wang, Feng Cheng, Jacentha Buggs, Hermann Koepsell, Volker Vallon, Ruisheng Liu

J Am Soc Nephrol. 2019 Apr; 30(4): 578–593. Published online 2019 Mar 13. doi: 10.1681/ASN.2018080844

PMCID:: PMC6442354

Abstract Article

Select item 638319417.

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

Aleksandra Novikov, Yiling Fu, Winnie Huang, Brent Freeman, Rohit Patel, Charlotte van Ginkel, Hermann Koepsell, Meinrad Busslinger, Akira Onishi, Josselin Nespoux, Volker Vallon

Am J Physiol Renal Physiol. 2019 Jan 1; 316(1): F173–F185. Published online 2018 Nov 14. doi: 10.1152/ajprenal.00462.2018

PMCID:: PMC6383194

Abstract Article

Select item 632319218.

SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels

Takayoshi Suga, Osamu Kikuchi, Masaki Kobayashi, Sho Matsui, Hiromi Yokota-Hashimoto, Eri Wada, Daisuke Kohno, Tsutomu Sasaki, Kazusane Takeuchi, Satoru Kakizaki, Masanobu Yamada, Tadahiro Kitamura

Mol Metab. 2019 Jan; 19: 1–12. Published online 2018 Oct 27. doi: 10.1016/j.molmet.2018.10.009

PMCID:: PMC6323192

Abstract Article PDF–2.4M

Select item 602631819.

Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet

Markus Mühlemann, Daniela Zdzieblo, Alexandra Friedrich, Constantin Berger, Christoph Otto, Heike Walles, Hermann Koepsell, Marco Metzger

Mol Metab. 2018 Jul; 13: 67–76. Published online 2018 May 23. doi: 10.1016/j.molmet.2018.05.011

PMCID:: PMC6026318

Abstract Article PDF–1.9M

Select item 562672920.

Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy

Madhuri S. Salker, Yogesh Singh, Ni Zeng, Hong Chen, Shaqiu Zhang, Anja T Umbach, Hajar Fakhri, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Ruban R. Peter Durairaj, Flavio S. V. Barros, Pavle Vrljicak, Sascha Ott, Sara Y Brucker, Diethelm Wallwiener, Ivana Vrhovac Madunić, Davorka Breljak, Ivan Sabolić, Hermann Koepsell, Jan J. Brosens, Florian Lang

Sci Rep. 2017; 7: 12612. Published online 2017 Oct 3. doi: 10.1038/s41598-017-11674-3

PMCID:: PMC5626729

Abstract Article PDF–1.6M

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