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Items: 1 to 20 of 41

1.
FBXO11 regulates bone development
Hong Huang, Jianrong Lu, Ikramuddin Aukhil, Colton Yu, Brinda Bhut, Julie Marchesan, Flavia Pirih, Jia Chang
Bone. Author manuscript; available in PMC 2024 Apr 11.
Published in final edited form as: Bone. 2023 May; 170: 116709. Published online 2023 Mar 1. doi: 10.1016/j.bone.2023.116709
PMCID:
PMC11008459
AbstractArticlePDF–1.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA
Yusuke Kasuga, Ryota Ouda, Masashi Watanabe, Xin Sun, Miki Kimura, Shigetsugu Hatakeyama, Koichi S. Kobayashi
Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2218955120. Published online 2023 Jun 6. doi: 10.1073/pnas.2218955120
PMCID:
PMC10268274
AbstractArticlePDF–2.3M
4.
FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative disease
Christof Schneider, Ning Kon, Letizia Amadori, Qiong Shen, Friederike H. Schwartz, Benjamin Tischler, Marion Bossennec, David Dominguez-Sola, Govind Bhagat, Wei Gu, Katia Basso, Riccardo Dalla-Favera
Blood. 2016 Aug 4; 128(5): 660–666. Published online 2020 Nov 24. doi: 10.1182/blood-2015-11-684357
Correction in:
Blood. 2023 Dec 14; 142(24): 2125.
PMCID:
PMC9709922
AbstractArticle
5.
Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes
Ali Azar, Mahmood F. Bhutta, Jorge Del-Pozo, Elspeth Milne, Michael Cheeseman
Front Genet. 2022; 13: 985214. Published online 2022 Sep 28. doi: 10.3389/fgene.2022.985214
PMCID:
PMC9555619
AbstractArticlePDF–5.1M
6.
Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma
Chiara Pighi, Taek-Chin Cheong, Mara Compagno, Enrico Patrucco, Maddalena Arigoni, Martina Olivero, Qi Wang, Cristina López, Stephan H. Bernhart, Bruno M. Grande, Teresa Poggio, Fernanda Langellotto, Lisa Bonello, Riccardo Dall’Olio, Sandra Martínez-Martín, Luca Molinaro, Paola Francia di Celle, Jonathan R. Whitfield, Laura Soucek, Claudia Voena, Raffaele A. Calogero, Ryan D. Morin, Louis M. Staudt, Reiner Siebert, Alberto Zamò, Roberto Chiarle
Blood Adv. 2021 Dec 14; 5(23): 5239–5257. Published online 2021 Dec 8. doi: 10.1182/bloodadvances.2021005682
PMCID:
PMC9153037
AbstractArticlePDF–3.2M
7.
The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa
Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman
Dis Model Mech. 2022 Mar 1; 15(3): dmm049034. Published online 2022 Mar 30. doi: 10.1242/dmm.049034
PMCID:
PMC8990926
AbstractArticle
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
The Jeff Mouse Mutant Model for Chronic Otitis Media Manifests Gain-of-Function as Well as Loss-of-Function Effects
Oana Kubinyecz, Pratik P. Vikhe, Thomas Purnell, Steve D. M. Brown, Hilda Tateossian
Front Genet. 2020; 11: 498. Published online 2020 May 19. doi: 10.3389/fgene.2020.00498
PMCID:
PMC7248398
AbstractArticlePDF–2.7M
10.
Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media
Pratik P. Vikhe, Hilda Tateossian, Gurpreet Bharj, Steve D.M. Brown, Derek W. Hood
Front Genet. 2020; 11: 50. Published online 2020 Feb 11. doi: 10.3389/fgene.2020.00050
PMCID:
PMC7026503
AbstractArticlePDF–998K
11.
CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
Chang Jiang, Stephen J. Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G. Doench, Roberto Chiarle, Benjamin E. Gewurz
Cell Rep. Author manuscript; available in PMC 2019 Aug 6.
Published in final edited form as: Cell Rep. 2019 Jul 30; 28(5): 1307–1322.e8. doi: 10.1016/j.celrep.2019.06.079
PMCID:
PMC6684324
AbstractArticlePDF–2.9M
12.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
13.
Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model
Jorge del-Pozo, Neil MacIntyre, Ali Azar, James Glover, Elspeth Milne, Michael Cheeseman
Dis Model Mech. 2019 Mar 1; 12(3): dmm038315. Published online 2019 Mar 21. doi: 10.1242/dmm.038315
PMCID:
PMC6451434
AbstractArticle
14.
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
Sofie Otzen Bagger, Branden Michael Hopkinson, Deo Prakash Pandey, Mads Bak, Andreas Vincent Brydholm, Rene Villadsen, Kristian Helin, Lone Rønnov-Jessen, Ole William Petersen, Jiyoung Kim
Mol Cancer. 2018; 17: 171. Published online 2018 Dec 10. doi: 10.1186/s12943-018-0918-6
PMCID:
PMC6287350
AbstractArticlePDF–3.7M
15.
A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse
Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman
Dis Model Mech. 2016 Jan 1; 9(1): 69–79. doi: 10.1242/dmm.021659
PMCID:
PMC4728332
AbstractArticle
16.
Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung
Hilda Tateossian, Susan Morse, Michelle M. Simon, Charlotte H. Dean, Steve D. M. Brown
Dis Model Mech. 2015 Dec 1; 8(12): 1531–1542. doi: 10.1242/dmm.022426
PMCID:
PMC4728322
AbstractArticle
17.
FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development
Yue Jin, Anitha K. Shenoy, Samuel Doernberg, Hao Chen, Huacheng Luo, Huangxuan Shen, Tong Lin, Miriam Tarrash, Qingsong Cai, Xin Hu, Ryan Fiske, Ting Chen, Lizi Wu, Kamal A. Mohammed, Veerle Rottiers, Siu Sylvia Lee, Jianrong Lu
Cancer Lett. Author manuscript; available in PMC 2016 Jun 28.
Published in final edited form as: Cancer Lett. 2015 Jun 28; 362(1): 70–82. Published online 2015 Mar 28. doi: 10.1016/j.canlet.2015.03.037
PMCID:
PMC4406488
AbstractArticlePDF–1.6M
18.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
AbstractArticlePDF–1.4M
19.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
20.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M

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