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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Downregulation of miR-497-5p Improves Sepsis-Induced Acute Lung Injury by Targeting IL2RB
Wei Lou, Jieping Yan, Weisi Wang
Biomed Res Int. 2021; 2021: 6624702. Published online 2021 Apr 12. doi: 10.1155/2021/6624702
PMCID:
PMC8057895
AbstractArticlePDF–2.4M
3.
Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells
Gabriela M. Wiedemann, Simon Grassmann, Colleen M. Lau, Moritz Rapp, Alejandro V. Villarino, Christin Friedrich, Georg Gasteiger, John J. O’Shea, Joseph C. Sun
Cell Rep. Author manuscript; available in PMC 2020 Dec 30.
Published in final edited form as: Cell Rep. 2020 Dec 15; 33(11): 108498. doi: 10.1016/j.celrep.2020.108498
PMCID:
PMC7773031
AbstractArticlePDF–1.7M
4.
Chronic shift‐lag promotes NK cell ageing and impairs immunosurveillance in mice by decreasing the expression of CD122
Xiaokang Zeng, Caiying Liang, Jie Yao
J Cell Mol Med. 2020 Dec; 24(24): 14583–14595. Published online 2020 Nov 13. doi: 10.1111/jcmm.16088
PMCID:
PMC7754032
AbstractArticlePDF–2.1M
5.
The abundance and availability of cytokine receptor IL-2Rβ (CD122) constrain the lymphopenia-induced homeostatic proliferation of naïve CD4 T cells
Hilary R. Keller, Hye Kyung Kim, Yuna Jo, Ronald E. Gress, Changwan Hong, Jung-Hyun Park
J Immunol. Author manuscript; available in PMC 2021 Jun 15.
Published in final edited form as: J Immunol. 2020 Jun 15; 204(12): 3227–3235. Published online 2020 May 11. doi: 10.4049/jimmunol.1901276
PMCID:
PMC7334900
AbstractArticlePDF–1.7M
6.
The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration
Aurore L'honoré, Pierre-Henri Commère, Elisa Negroni, Giorgia Pallafacchina, Bertrand Friguet, Jacques Drouin, Margaret Buckingham, Didier Montarras
eLife. 2018; 7: e32991. Published online 2018 Aug 14. doi: 10.7554/eLife.32991
PMCID:
PMC6191287
AbstractArticlePDF–3.2M
7.
CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection
David V. Mathews, Ying Dong, Laura B. Higginbotham, Steven C. Kim, Cynthia P. Breeden, Elizabeth A. Stobert, Joseph Jenkins, J. Yun Tso, Christian P. Larsen, Andrew B. Adams
J Clin Invest. 2018 Oct 1; 128(10): 4557–4572. Published online 2018 Sep 17. doi: 10.1172/JCI95914
PMCID:
PMC6159972
AbstractArticlePDF–5.0M
8.
Altered homeostasis and development of regulatory T cell subsets represents an IL-2R–dependent risk for diabetes in NOD mice
Connor J. Dwyer, Allison L. Bayer, Carmen Fotino, Liping Yu, Cecilia Cabello-Kindelan, Natasha C. Ward, Kevin H. Toomer, Zhibin Chen, Thomas R. Malek
Sci Signal. Author manuscript; available in PMC 2018 Dec 19.
Published in final edited form as: Sci Signal. 2017 Dec 19; 10(510): eaam9563. Published online 2017 Dec 19. doi: 10.1126/scisignal.aam9563
PMCID:
PMC5903848
AbstractArticlePDF–1.6M
9.
IL-2Rβ Abundance Differentially Tunes IL-2 Signaling Dynamics in CD4+ and CD8+ T Cells
Geoffrey A. Smith, Jack Taunton, Arthur Weiss
Sci Signal. Author manuscript; available in PMC 2018 Jun 19.
Published in final edited form as: Sci Signal. 2017 Dec 19; 10(510): eaan4931. Published online 2017 Dec 19. doi: 10.1126/scisignal.aan4931
PMCID:
PMC5741096
AbstractArticlePDF–1.4M
10.
Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy
Deborah Charych, Samira Khalili, Vidula Dixit, Peter Kirk, Thomas Chang, John Langowski, Werner Rubas, Stephen K. Doberstein, Michael Eldon, Ute Hoch, Jonathan Zalevsky
PLoS One. 2017; 12(7): e0179431. Published online 2017 Jul 5. doi: 10.1371/journal.pone.0179431
PMCID:
PMC5497954
AbstractArticlePDF–5.5M
11.
IL-2 prevents deletion of developing T-regulatory cells in the thymus
Daniel Y Hu, Rushika C Wirasinha, Christopher C Goodnow, Stephen R Daley
Cell Death Differ. 2017 Jun; 24(6): 1007–1016. Published online 2017 May 12. doi: 10.1038/cdd.2017.38
PMCID:
PMC5442470
AbstractArticlePDF–2.7M
12.
IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation
Petra D. Cravens, Rehana Z. Hussain, William A. Miller-Little, Li-Hong Ben, Benjamin M. Segal, Emily Herndon, Olaf Stüve
PLoS One. 2016; 11(10): e0165248. Published online 2016 Oct 25. doi: 10.1371/journal.pone.0165248
PMCID:
PMC5079572
AbstractArticlePDF–1.9M
13.
An essential role for IL-2 receptor in regulatory T cell function
Takatoshi Chinen, Arun K. Kannan, Andrew G Levine, Xiying Fan, Ulf Klein, Ye Zheng, Georg Gasteiger, Yongqiang Feng, Jason D. Fontenot, Alexander Y. Rudensky
Nat Immunol. Author manuscript; available in PMC 2017 Mar 5.
Published in final edited form as: Nat Immunol. 2016 Nov; 17(11): 1322–1333. Published online 2016 Sep 5. doi: 10.1038/ni.3540
PMCID:
PMC5071159
AbstractArticlePDF–2.9M
14.
IL2Rβ-dependent signals drive terminal exhaustion and suppress memory development during chronic viral infection
Jean-Christophe Beltra, Sara Bourbonnais, Nathalie Bédard, Tania Charpentier, Moana Boulangé, Eva Michaud, Ines Boufaied, Julie Bruneau, Naglaa H. Shoukry, Alain Lamarre, Hélène Decaluwe
Proc Natl Acad Sci U S A. 2016 Sep 13; 113(37): E5444–E5453. Published online 2016 Aug 29. doi: 10.1073/pnas.1604256113
PMCID:
PMC5027416
AbstractArticlePDF–1.6M
15.
IL‐18‐induced expression of high‐affinity IL‐2R on murine NK cells is essential for NK‐cell IFN‐γ production during murine Plasmodium yoelii infection
Kerstin A. Stegmann, J. Brian De Souza, Eleanor M. Riley
Eur J Immunol. 2015 Dec; 45(12): 3431–3440. Published online 2015 Oct 21. doi: 10.1002/eji.201546018
PMCID:
PMC4982096
AbstractArticlePDF–1.4M
16.
IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa
Xiaomei Yuan, Michael J. Dee, Norman H. Altman, Thomas R. Malek
J Immunol. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: J Immunol. 2015 Feb 1; 194(3): 1334–1346. Published online 2014 Dec 19. doi: 10.4049/jimmunol.1400955
PMCID:
PMC4297734
AbstractArticlePDF–1.7M
17.
The Rag2–Il2rb–Dmd– Mouse: a Novel Dystrophic and Immunodeficient Model to Assess Innovating Therapeutic Strategies for Muscular Dystrophies
Denis Vallese, Elisa Negroni, Stéphanie Duguez, Arnaud Ferry, Capucine Trollet, Ahmed Aamiri, Christian AJ Vosshenrich, Ernst-Martin Füchtbauer, James P Di Santo, Libero Vitiello, Gillian Butler-Browne, Vincent Mouly
Mol Ther. 2013 Oct; 21(10): 1950–1957. Prepublished online 2013 Aug 23. Published online 2013 Sep 24. doi: 10.1038/mt.2013.186
PMCID:
PMC3808143
AbstractArticlePDF–892K
18.
CD8α+ DC trans-presentation of IL-15 to naïve CD8+ T cells produces antigen inexperienced T cells in the periphery with memory phenotype and function
Tomasz Sosinowski, Jason T. White, Eric Cross, Catherine Haluszczak, Philippa Marrack, Laurent Gapin, Ross M. Kedl
J Immunol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Immunol. 2013 Mar 1; 190(5): 1936–1947. Published online 2013 Jan 25. doi: 10.4049/jimmunol.1203149
PMCID:
PMC3578102
AbstractArticlePDF–3.7M
19.
IL-2R signaling is essential for functional maturation of T regulatory cells during thymic development
Guoyan Cheng, Aixin Yu, Michael J. Dee, Thomas R. Malek
J Immunol. Author manuscript; available in PMC 2014 Feb 15.
Published in final edited form as: J Immunol. 2013 Feb 15; 190(4): 1567–1575. Published online 2013 Jan 11. doi: 10.4049/jimmunol.1201218
PMCID:
PMC3563871
AbstractArticlePDF–1.4M
20.
Expansion of a Restricted Residual Host Treg Repertoire is Dependent on IL-2 Following Experimental Autologous HSCT
Allison L. Bayer, Jackeline Chirinos, Cecilia Cabello, Jing Yang, Takaji Matsutani, Thomas R. Malek, Robert B. Levy
Eur J Immunol. Author manuscript; available in PMC 2012 Dec 6.
Published in final edited form as: Eur J Immunol. 2011 Dec; 41(12): 3467–3478. Published online 2011 Oct 31. doi: 10.1002/eji.201141611
PMCID:
PMC3516388
AbstractArticlePDF–1.6M

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