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Select item 110366401.

Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging

Lin-Lin Hu, Mei-Hua Liao, Ya-Xi Liu, Chun-Hua Xing, Lan-Lan Nong, Feng-Lian Yang, Shao-Chen Sun

Biol Direct. 2024; 19: 29. Published online 2024 Apr 23. doi: 10.1186/s13062-024-00471-4

PMCID:: PMC11036640

Abstract Article PDF–11M

Select item 109580332.

Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet

Nat Commun. 2024; 15: 2487. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46146-6

PMCID:: PMC10958033

Abstract Article PDF–5.0M

Select item 106929013.

AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss

Mariana S.P. Ribeiro, Lucas G.R. Venturini, Cesar A. Speck-Hernandez, Paulo V.G. Alabarse, Thais Xavier, Thaise M. Taira, Letícia F. Duffles, Fernando Q. Cunha, Sandra Y. Fukada

J Biol Chem. 2023 Dec; 299(12): 105379. Published online 2023 Oct 21. doi: 10.1016/j.jbc.2023.105379

PMCID:: PMC10692901

Abstract Article PDF–2.5M

Select item 105426164.

Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion

Yiqi Yang, Kai Yuan, Yihao Liu, Qishan Wang, Yixuan Lin, Shengbing Yang, Kai Huang, Tianyou Kan, Yuxin Zhang, Mingming Xu, Zhifeng Yu, Qiming Fan, Yugang Wang, Hanjun Li, Tingting Tang

Cell Prolif. 2023 Oct; 56(10): e13476. Published online 2023 Apr 11. doi: 10.1111/cpr.13476

PMCID:: PMC10542616

Abstract Article PDF–15M

Select item 105206375.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 101271056.

Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK

Felipe A. Bustamante-Barrientos, Maxs Méndez-Ruette, Luis Molina, Tania Koning, Pamela Ehrenfeld, Carlos B. González, Ursula Wyneken, Roberto Henzi, Luis Federico Bátiz

Front Cell Dev Biol. 2023; 11: 1061777. Published online 2023 Apr 11. doi: 10.3389/fcell.2023.1061777

PMCID:: PMC10127105

Abstract Article PDF–4.2M

Select item 99682977.

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee

Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y

PMCID:: PMC9968297

Abstract Article PDF–4.4M

Select item 98905348.

AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia

Ping Xu, Yangxi Zheng, Jiujiang Liao, Mingyu Hu, Yike Yang, Baozhen Zhang, Mark D. Kilby, Huijia Fu, Yamin Liu, Fumei Zhang, Liling Xiong, Xiyao Liu, Huili Jin, Yue Wu, Jiayu Huang, Tingli Han, Li Wen, Rufei Gao, Yong Fu, Xiujun Fan, Hongbo Qi, Philip N. Baker, Chao Tong

Cell Prolif. 2023 Feb; 56(2): e13358. Published online 2022 Dec 8. doi: 10.1111/cpr.13358

PMCID:: PMC9890534

Abstract Article PDF–14M

Select item 98428659.

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

Iain R. Phair, Raid B. Nisr, Andrew J.M. Howden, Magdalena Sovakova, Noor Alqurashi, Marc Foretz, Douglas Lamont, Benoit Viollet, Graham Rena

Mol Metab. 2023 Feb; 68: 101661. Published online 2022 Dec 28. doi: 10.1016/j.molmet.2022.101661

PMCID:: PMC9842865

Abstract Article PDF–3.1M

Select item 982946910.

Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu

Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022

PMCID:: PMC9829469

Abstract Article

Select item 981804711.

A Therapeutically Targetable NOTCH1–SIRT1–KAT7 Axis in T-cell Leukemia

Olga Lancho, Amartya Singh, Victoria da Silva-Diz, Maya Aleksandrova, Jesminara Khatun, Luca Tottone, Patricia Renck Nunes, Shirley Luo, Caifeng Zhao, Haiyan Zheng, Eric Chiles, Zhenyu Zuo, Pedro P. Rocha, Xiaoyang Su, Hossein Khiabanian, Daniel Herranz

Blood Cancer Discov. 2023 Jan 6; 4(1): 12–33. Published online 2022 Nov 1. doi: 10.1158/2643-3230.BCD-22-0098

PMCID:: PMC9818047

Abstract Article PDF–26M

Select item 981368112.

Manassantin B attenuates obesity by inhibiting adipogenesis and lipogenesis in an AMPK dependent manner

Jie Cai, Gu Qiong, Chanjuan Li, Lulu Sun, Yuhong Luo, Shengheng Yuan, Frank J. Gonzalez, Jun Xu

FASEB J. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: FASEB J. 2021 May; 35(5): e21496. doi: 10.1096/fj.202002126RR

PMCID:: PMC9813681

Abstract Article PDF–2.3M

Select item 977708113.

Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation

Ying Zhou, Jia-Jie Yang, Yuan Cheng, Ge-Xuan Feng, Rong-Hui Yang, Yuan Yuan, Li-Yong Wang, Miao Wang, Lu Kong

Cells. 2022 Dec; 11(24): 3988. Published online 2022 Dec 9. doi: 10.3390/cells11243988

PMCID:: PMC9777081

Abstract Article PDF–4.6M

Select item 974763214.

Glucagon changes substrate preference in gluconeogenesis

Huiting Xu, Yujue Wang, Hyokjoon Kwon, Ankit Shah, Katarzyna Kalemba, Xiaoyang Su, Ling He, Fredric E. Wondisford

J Biol Chem. 2022 Dec; 298(12): 102708. Published online 2022 Nov 17. doi: 10.1016/j.jbc.2022.102708

PMCID:: PMC9747632

Abstract Article PDF–1.1M

Select item 966437815.

NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function

Ajay Kumar, Emily L. Yarosz, Anthony Andren, Li Zhang, Costas A. Lyssiotis, Cheong-Hee Chang

Cell Rep. Author manuscript; available in PMC 2022 Nov 15.

Published in final edited form as: Cell Rep. 2022 Oct 25; 41(4): 111516. doi: 10.1016/j.celrep.2022.111516

PMCID:: PMC9664378

Abstract Article PDF–2.5M

Select item 960421416.

AMPK Amplifies IL2–STAT5 Signaling to Maintain Stability of Regulatory T Cells in Aged Mice

Ram Hari Pokhrel, Ben Kang, Maheshwor Timilshina, Jae-Hoon Chang

Int J Mol Sci. 2022 Oct; 23(20): 12384. Published online 2022 Oct 16. doi: 10.3390/ijms232012384

PMCID:: PMC9604214

Abstract Article PDF–3.4M

Select item 958481517.

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin

Nat Metab. 2022; 4(10): 1369–1401. Published online 2022 Oct 10. doi: 10.1038/s42255-022-00640-7

PMCID:: PMC9584815

Abstract Article PDF–9.0M

Select item 948193318.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 941819219.

AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death

Javier Moral-Sanz, Sophronia A. Lewis, Sandy MacMillan, Marco Meloni, Heather McClafferty, Benoit Viollet, Marc Foretz, Jorge del-Pozo, A. Mark Evans

Nat Commun. 2022; 13: 5034. Published online 2022 Aug 26. doi: 10.1038/s41467-022-32568-7

PMCID:: PMC9418192

Abstract Article PDF–8.8M

Select item 941657020.

Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1

Sa Zhou, Jiamin Xue, Jingbo Shan, Yingxiang Hong, Wenkang Zhu, Zhiyan Nie, Yujie Zhang, Nanxi Ji, Xuegang Luo, Tongcun Zhang, Wenjian Ma

Nutrients. 2022 Aug; 14(16): 3338. Published online 2022 Aug 15. doi: 10.3390/nu14163338

PMCID:: PMC9416570

Abstract Article PDF–4.3M

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