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Select item 61424241.

Increased inflammation, endoplasmic reticulum stress and oxidative stress in endothelial and macrophage cells exacerbate atherosclerosis in ApoCIII transgenic mice

Han Yingchun, Ma Yahong, Wen Jiangping, He Xiaokui, Zhang Xiaohong

Lipids Health Dis. 2018; 17: 220. Published online 2018 Sep 17. doi: 10.1186/s12944-018-0867-5

PMCID:: PMC6142424

Article PDF–1.5M

Select item 60695932.

Key differences between apoC-III regulation and expression in intestine and liver

Gabrielle West, Cayla Rodia, Diana Li, Zania Johnson, Hongli Dong, Alison B. Kohan

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Biochem Biophys Res Commun. 2017 Sep 23; 491(3): 747–753. Published online 2017 Jul 21. doi: 10.1016/j.bbrc.2017.07.116

PMCID:: PMC6069593

Article PDF–679K

Select item 58805013.

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

Mikael Larsson, Christopher M. Allan, Patrick J. Heizer, Yiping Tu, Norma P. Sandoval, Rachel S. Jung, Rosemary L. Walzem, Anne P. Beigneux, Stephen G. Young, Loren G. Fong

J Lipid Res. 2018 Apr; 59(4): 706–713. Published online 2018 Feb 15. doi: 10.1194/jlr.M083832

PMCID:: PMC5880501

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Select item 56693754.

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

Sumeet A Khetarpal, Xuemei Zeng, John S Millar, Cecilia Vitali, Amritha Varshini Hanasoge Somasundara, Paolo Zanoni, James A Landro, Nicole Barucci, William J Zavadoski, Zhiyuan Sun, Hans de Haard, Ildikó V Toth, Gina M Peloso, Pradeep Natarajan, Marina Cuchel, Sissel Lund-Katz, Michael C Phillips, Alan R Tall, Sekar Kathiresan, Paul DaSilva-Jardine, Nathan A Yates, Daniel J Rader

Nat Med. Author manuscript; available in PMC 2017 Nov 3.

Published in final edited form as: Nat Med. 2017 Sep; 23(9): 1086–1094. Published online 2017 Aug 21. doi: 10.1038/nm.4390

PMCID:: PMC5669375

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Select item 56656665.

The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation

Meenakshi Sundaram, Kaitlin R. Curtis, Mohsen Amir Alipour, Nicholas D. LeBlond, Kaitlyn D. Margison, Rebecca A. Yaworski, Robin J. Parks, Adam D. McIntyre, Robert A. Hegele, Morgan D. Fullerton, Zemin Yao

J Lipid Res. 2017 Nov; 58(11): 2188–2196. Published online 2017 Sep 8. doi: 10.1194/jlr.M077313

PMCID:: PMC5665666

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Select item 50752066.

Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats

Soon-Sen Leow, Julia Bolsinger, Andrzej Pronczuk, K. C. Hayes, Ravigadevi Sambanthamurthi

Genes Nutr. 2016; 11: 29. Published online 2016 Oct 22. doi: 10.1186/s12263-016-0545-z

PMCID:: PMC5075206

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Select item 43966107.

Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis

Roman Thaler, Ines Sturmlechner, Silvia Spitzer, Scott M. Riester, Monika Rumpler, Jochen Zwerina, Klaus Klaushofer, Andre J. van Wijnen, Franz Varga

FASEB J. 2015 Apr; 29(4): 1344–1359. Published online 2014 Dec 9. doi: 10.1096/fj.14-265512

PMCID:: PMC4396610

Article

Select item 38100908.

Tubular von Hippel-Lindau Knockout Protects against Rhabdomyolysis-Induced AKI

Michael Fähling, Susanne Mathia, Alexander Paliege, Robert Koesters, Ralf Mrowka, Harm Peters, Pontus Börje Persson, Hans-Hellmut Neumayer, Sebastian Bachmann, Christian Rosenberger

J Am Soc Nephrol. 2013 Nov; 24(11): 1806–1819. Published online 2013 Aug 22. doi: 10.1681/ASN.2013030281

PMCID:: PMC3810090

Article

Select item 38088709.

Candidate genes for limiting cholestatic intestinal injury identified by gene expression profiling

Samuel M Alaish, Jennifer Timmons, Alexis Smith, Marguerite S Buzza, Ebony Murphy, Aiping Zhao, Yezhou Sun, Douglas J Turner, Terez Shea-Donahue, Toni M Antalis, Alan Cross, Susan G Dorsey

Physiol Rep. 2013 Sep; 1(4): e00073. Published online 2013 Sep 17. doi: 10.1002/phy2.73

PMCID:: PMC3808870

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Select item 354363710.

Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways

Haiyan Zhang, Wen-Jun Shen, Yuan Cortez, Fredric B. Kraemer, Salman Azhar

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1): G72–G86. Published online 2012 Oct 25. doi: 10.1152/ajpgi.00328.2012

PMCID:: PMC3543637

Article

Select item 344554111.

Global Renal Gene Expression Profiling Analysis in B₂-Kinin Receptor Null Mice: Impact of Diabetes

Miran A. Jaffa, Firas Kobeissy, Moustafa Al Hariri, Hussein Chalhoub, Assaad Eid, Fuad N. Ziyadeh, Ayad A. Jaffa

PLoS One. 2012; 7(9): e44714. Published online 2012 Sep 18. doi: 10.1371/journal.pone.0044714

PMCID:: PMC3445541

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Select item 292999112.

Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

Keisuke Yamamoto, Kazuna Takahara, Seiichi Oyadomari, Tetsuya Okada, Takashi Sato, Akihiro Harada, Kazutoshi Mori

Mol Biol Cell. 2010 Sep 1; 21(17): 2975–2986. doi: 10.1091/mbc.E09-02-0133

PMCID:: PMC2929991

Article PDF–2.6M

Select item 275912913.

Insulin Sensitizing Pharmacology of Thiazolidinediones Correlates with Mitochondrial Gene Expression rather than Activation of PPARγ

Charles W. Bolten, Patrick M. Blanner, William G. McDonald, Nicholas R. Staten, Richard A. Mazzarella, Graciela B. Arhancet, Martin F. Meier, David J. Weiss, Patrick M. Sullivan, Alexander E. Hromockyj, Rolf F. Kletzien, Jerry R. Colca

Gene Regul Syst Bio. 2007; 1: 73–82. Published online 2007 Sep 17.

PMCID:: PMC2759129

Article PDF–545K

Select item 274728014.

Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum

Alejandra Rodriguez, Tiina Luukkaala, Robert E. Fleming, Robert S. Britton, Bruce R. Bacon, Seppo Parkkila

PLoS One. 2009; 4(9): e7212. Published online 2009 Sep 29. doi: 10.1371/journal.pone.0007212

PMCID:: PMC2747280

Article PDF–257K

Select item 272695015.

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

Gwendal Le Martelot, Thierry Claudel, David Gatfield, Olivier Schaad, Benoît Kornmann, Giuseppe Lo Sasso, Antonio Moschetta, Ueli Schibler

PLoS Biol. 2009 Sep; 7(9): e1000181. Published online 2009 Sep 1. doi: 10.1371/journal.pbio.1000181

PMCID:: PMC2726950

Article PDF–565K

Select item 271932216.

Decreased Expression of Cholesterol 7α-Hydroxylase and Altered Bile Acid Metabolism in Apobec-1^−/− Mice Lead to Increased Gallstone Susceptibility

Yan Xie, Valerie Blanc, Thomas A. Kerr, Susan Kennedy, Jianyang Luo, Elizabeth P. Newberry, Nicholas O. Davidson

J Biol Chem. 2009 Jun 19; 284(25): 16860–16871. Published online 2009 Apr 22. doi: 10.1074/jbc.M109.010173

PMCID:: PMC2719322

Article PDF–651K

Select item 268492417.

Bezafibrate at Clinically Relevant Doses Decreases Serum/Liver Triglycerides via Down-Regulation of Sterol Regulatory Element-Binding Protein-1c in Mice: A Novel Peroxisome Proliferator-Activated Receptor α-Independent Mechanism

Takero Nakajima, Naoki Tanaka, Hiroki Kanbe, Atsushi Hara, Yuji Kamijo, Xiaowei Zhang, Frank J. Gonzalez, Toshifumi Aoyama

Mol Pharmacol. 2009 Apr; 75(4): 782–792. Published online 2009 Jan 5. doi: 10.1124/mol.108.052928

PMCID:: PMC2684924

Article PDF–565K

Select item 266618418.

Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice

Yan Xie, Elizabeth P. Newberry, Susan M. Kennedy, Jianyang Luo, Nicholas O. Davidson

J Lipid Res. 2009 May; 50(5): 977–987. doi: 10.1194/jlr.M800645-JLR200

PMCID:: PMC2666184

Article PDF–1.3M

Select item 226690719.

Rosiglitazone but not losartan prevents Nrf-2 dependent CD36 gene expression up-regulation in an in vivo atherosclerosis model

Y Hernandez-Trujillo, F Rodriguez-Esparragon, A Macias-Reyes, A Caballero-Hidalgo, Jose C Rodriguez-Perez

Cardiovasc Diabetol. 2008; 7: 3. Published online 2008 Feb 26. doi: 10.1186/1475-2840-7-3

PMCID:: PMC2266907

Article PDF–724K

Select item 217448720.

Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy

Amanda M Gonzales, Robert A Orlando

Nutr Metab (Lond) 2007; 4: 22. Published online 2007 Oct 30. doi: 10.1186/1743-7075-4-22

PMCID:: PMC2174487

Article PDF–762K

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