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Select item 110149571.

Endothelial DR6 in blood-brain barrier malfunction in Alzheimer’s disease

Xiaomin Huang, Junhua Qi, Yixun Su, Ying Zhou, Qi Wang, Taida Huang, Dongdong Xue, Yunxin Zeng, Alexei Verkhratsky, Benjie Zhou, Hui Chen, Chenju Yi

Cell Death Dis. 2024 Apr; 15(4): 258. Published online 2024 Apr 12. doi: 10.1038/s41419-024-06639-0

PMCID:: PMC11014957

Abstract Article PDF–6.0M

Select item 58816262.

Non‐cell‐autonomous function of DR6 in Schwann cell proliferation

Alessio Colombo, Hung‐En Hsia, Mengzhe Wang, Peer‐Hendrik Kuhn, Monika S Brill, Paolo Canevazzi, Regina Feederle, Carla Taveggia, Thomas Misgeld, Stefan F Lichtenthaler

EMBO J. 2018 Apr 3; 37(7): e97390. Published online 2018 Feb 19. doi: 10.15252/embj.201797390

PMCID:: PMC5881626

Abstract Article PDF–2.8M

Select item 53605223.

Death Receptor 6 promotes Wallerian degeneration in peripheral axons

Kanchana K. Gamage, Irene Cheng, Rachel E. Park, Mardeen S. Karim, Kazusa Edamura, Christopher Hughes, Anthony J. Spano, Alev Erisir, Christopher D. Deppmann

Curr Biol. Author manuscript; available in PMC 2018 Mar 20.

Published in final edited form as: Curr Biol. 2017 Mar 20; 27(6): 890–896. Published online 2017 Mar 9. doi: 10.1016/j.cub.2017.01.062

Correction in:: Curr Biol. 2017 Apr 24; 27(8): 1250.

PMCID:: PMC5360522

Abstract Article PDF–2.1M

Select item 52160824.

Death receptor 6 contributes to autoimmunity in lupus-prone mice

Daisuke Fujikura, Masahiro Ikesue, Tsutomu Endo, Satoko Chiba, Hideaki Higashi, Toshimitsu Uede

Nat Commun. 2017; 8: 13957. Published online 2017 Jan 3. doi: 10.1038/ncomms13957

PMCID:: PMC5216082

Abstract Article PDF–1.5M

Select item 37760545.

Death Receptor 6 Regulates Adult Experience-Dependent Cortical Plasticity

Sally A. Marik, Olav Olsen, Marc Tessier-Lavigne, Charles D. Gilbert

J Neurosci. 2013 Sep 18; 33(38): 14998–15003. doi: 10.1523/JNEUROSCI.2398-13.2013

PMCID:: PMC3776054

Abstract Article PDF–1.3M

Select item 68804666.

p75NTR and DR6 Regulate Distinct Phases of Axon Degeneration Demarcated by Spheroid Rupture

Yu Yong, Kanchana Gamage, Irene Cheng, Kelly Barford, Anthony Spano, Bettina Winckler, Christopher Deppmann

J Neurosci. 2019 Nov 27; 39(48): 9503–9520. doi: 10.1523/JNEUROSCI.1867-19.2019

PMCID:: PMC6880466

Abstract Article PDF–13M

Select item 49483317.

Physiological role for amyloid precursor protein in adult experience-dependent plasticity

Sally A. Marik, Olav Olsen, Marc Tessier-Lavigne, Charles D. Gilbert

Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): 7912–7917. Published online 2016 Jun 27. doi: 10.1073/pnas.1604299113

PMCID:: PMC4948331

Abstract Article PDF–1.1M

Select item 21937998.

Enhanced B Cell Expansion, Survival, and Humoral Responses by Targeting Death Receptor 6

Clint S. Schmidt, Jinqi Liu, Tonghai Zhang, Ho Yeong Song, George Sandusky, Karen Mintze, Robert J. Benschop, Andrew Glasebrook, Derek D. Yang, Songqing Na

J Exp Med. 2003 Jan 6; 197(1): 51–62. doi: 10.1084/jem.20020617

PMCID:: PMC2193799

Abstract Article PDF–413K

Select item 21936839.

Impaired c-Jun Amino Terminal Kinase Activity and T Cell Differentiation in Death Receptor 6–deficient Mice

Haoran Zhao, Minhong Yan, Hua Wang, Sharon Erickson, Iqbal S. Grewal, Vishva M. Dixit

J Exp Med. 2001 Nov 19; 194(10): 1441–1448. doi: 10.1084/jem.194.10.1441

PMCID:: PMC2193683

Abstract Article PDF–166K

Select item 750884710.

Regulation of degenerative spheroids after injury

Yu Yong, Kanchana Gamage, Courtny Cushman, Anthony Spano, Christopher Deppmann

Sci Rep. 2020; 10: 15472. Published online 2020 Sep 22. doi: 10.1038/s41598-020-71906-x

PMCID:: PMC7508847

Abstract Article PDF–12M

Select item 841078911.

The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8

Jia-yuan Zhang, Bo Zhou, Ru-yue Sun, Yuan-li Ai, Kang Cheng, Fu-nan Li, Bao-rui Wang, Fan-jian Liu, Zhi-hong Jiang, Wei-jia Wang, Dawang Zhou, Hang-zi Chen, Qiao Wu

Cell Res. 2021 Sep; 31(9): 980–997. Published online 2021 May 19. doi: 10.1038/s41422-021-00506-9

PMCID:: PMC8410789

Abstract Article PDF–6.3M

Select item 660813812.

A Death Receptor 6-Amyloid Precursor Protein Pathway Regulates Synapse Density in the Mature CNS But Does Not Contribute to Alzheimer's Disease-Related Pathophysiology in Murine Models

Dara Y. Kallop, William J. Meilandt, Alvin Gogineni, Courtney Easley-Neal, Tiffany Wu, Adrian M. Jubb, Murat Yaylaoglu, Mehrdad Shamloo, Marc Tessier-Lavigne, Kimberly Scearce-Levie, Robby M Weimer

J Neurosci. 2014 May 7; 34(19): 6425–6437. doi: 10.1523/JNEUROSCI.4963-13.2014

PMCID:: PMC6608138

Abstract Article PDF–2.9M

Select item 596401413.

Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury

Kimberly A. Fernandes, Katherine L. Mitchell, Amit Patel, Olivia J. Marola, Peter Shrager, Donald J. Zack, Richard T. Libby1, Derek S. Welsbie

Exp Eye Res. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Exp Eye Res. 2018 Jun; 171: 54–61. Published online 2018 Mar 8. doi: 10.1016/j.exer.2018.03.007

PMCID:: PMC5964014

Abstract Article PDF–751K

Select item 517928514.

Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6

Jielu Hao, Qingqing Wei, Shuqin Mei, Lin Li, Yunchao Su, Changlin Mei, Zheng Dong

Kidney Int. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Kidney Int. 2017 Jan; 91(1): 106–118. Published online 2016 Sep 9. doi: 10.1016/j.kint.2016.07.017

PMCID:: PMC5179285

Abstract Article PDF–2.3M

Select item 401230315.

Genetic Analysis Reveals that Amyloid Precursor Protein and Death Receptor 6 Function in the Same Pathway to Control Axonal Pruning Independent of β-Secretase

Olav Olsen, Dara Y. Kallop, Todd McLaughlin, Sarah Huntwork-Rodriguez, Zhuhao Wu, Cynthia D. Duggan, David J. Simon, Yanmei Lu, Courtney Easley-Neal, Kentaro Takeda, Philip E. Hass, Alexander Jaworski, Dennis D.M. O'Leary, Robby M Weimer, Marc Tessier-Lavigne

J Neurosci. 2014 May 7; 34(19): 6438–6447. doi: 10.1523/JNEUROSCI.3522-13.2014

PMCID:: PMC4012303

Abstract Article PDF–3.6M

Select item 364133316.

A DR6/p75^NTR complex is responsible for β-amyloid-induced cortical neuron death

Y Hu, X Lee, Z Shao, D Apicco, G Huang, B J Gong, R B Pepinsky, S Mi

Cell Death Dis. 2013 Apr; 4(4): e579. Published online 2013 Apr 4. doi: 10.1038/cddis.2013.110

PMCID:: PMC3641333

Abstract Article PDF–1.6M

Select item 1076935017.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108