PMC Links for Gene (Select 94176) - PMC

Akihiko Nishikimi, Hideo Fukuhara, Wenjuan Su, Tsunaki Hongu, Shunsuke Takasuga, Hisashi Mihara, Qinhong Cao, Fumiyuki Sanematsu, Motomu Kanai, Hiroshi Hasegawa, Yoshihiko Tanaka, Masakatsu Shibasaki, Yasunori Kanaho, Takehiko Sasaki, Michael A. Frohman, Yoshinori Fukui

Science. Author manuscript; available in PMC 2013 Sep 4.

Published in final edited form as: Science. 2009 Apr 17; 324(5925): 384–387. Published online 2009 Mar 26. doi: 10.1126/science.1170179

PMCID:: PMC3761877

Article PDF–2.4M

Select item 34588225.

Dimerization of DOCK2 Is Essential for DOCK2-Mediated Rac Activation and Lymphocyte Migration

Masao Terasawa, Takehito Uruno, Sayako Mori, Mutsuko Kukimoto-Niino, Akihiko Nishikimi, Fumiyuki Sanematsu, Yoshihiko Tanaka, Shigeyuki Yokoyama, Yoshinori Fukui

PLoS One. 2012; 7(9): e46277. Published online 2012 Sep 26. doi: 10.1371/journal.pone.0046277

PMCID:: PMC3458822

Article PDF–1.2M

Select item 22132046.

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

Hongsi Jiang, Fan Pan, Laurie M. Erickson, Mei-Shiang Jang, Terukazu Sanui, Yuya Kunisaki, Takehiko Sasazuki, Masakazu Kobayashi, Yoshinori Fukui

J Exp Med. 2005 Oct 17; 202(8): 1121–1130. doi: 10.1084/jem.20050911

PMCID:: PMC2213204

Article PDF–2.5M

Select item 20643087.

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Yuya Kunisaki, Akihiko Nishikimi, Yoshihiko Tanaka, Ryosuke Takii, Mayuko Noda, Ayumi Inayoshi, Ken-ichi Watanabe, Fumiyuki Sanematsu, Takehiko Sasazuki, Takehiko Sasaki, Yoshinori Fukui

J Cell Biol. 2006 Aug 28; 174(5): 647–652. doi: 10.1083/jcb.200602142

PMCID:: PMC2064308

Article PDF–1.1M

Select item 96270448.

DOCK2 and phosphoinositide-3 kinase δ mediate two complementary signaling pathways for CXCR5-dependent B cell migration

Stefanie Wissmann, Bettina Stolp, Ana Marcos Jímenez, Jens V. Stein

Front Immunol. 2022; 13: 982383. Published online 2022 Oct 19. doi: 10.3389/fimmu.2022.982383

PMCID:: PMC9627044

Article PDF–4.0M

Select item 92801909.

Naïve Primary Mouse CD8⁺ T Cells Retain In Vivo Immune Responsiveness After Electroporation-Based CRISPR/Cas9 Genetic Engineering

Petra Pfenninger, Laura Yerly, Jun Abe

Front Immunol. 2022; 13: 777113. Published online 2022 Jun 30. doi: 10.3389/fimmu.2022.777113

PMCID:: PMC9280190

Article PDF–15M

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DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition

Guoqing Qian, Oluwaseun Adeyanju, Saptarshi Roy, Christudas Sunil, Ann Jeffers, Xia Guo, Mitsuo Ikebe, Steven Idell, Torry A. Tucker

Am J Respir Cell Mol Biol. 2022 Feb; 66(2): 171–182. Published online 2021 Oct 28. doi: 10.1165/rcmb.2021-0175OC

PMCID:: PMC8845130

Article PDF–1.7M

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DOCK2 regulates antifungal immunity by regulating RAC GTPase activity

Xiaojian Ma, Xi Tan, Bingbing Yu, Wanwei Sun, Heping Wang, Huijun Hu, Yanyun Du, Ruirui He, Ru Gao, Qianwen Peng, Zhihui Cui, Ting Pan, Xiong Feng, Junhan Wang, Chengqi Xu, Bin Zhu, Wei Liu, Chenhui Wang

Cell Mol Immunol. 2022 May; 19(5): 602–618. Published online 2022 Jan 25. doi: 10.1038/s41423-021-00835-0

PMCID:: PMC8787451

Article PDF–6.7M

Select item 692054312.

DOCK2 sets the threshold for entry into the virtual memory CD8⁺ T cell compartment by negatively regulating tonic TCR triggering

Vinay S Mahajan, Ezana Demissie, Faisal Alsufyani, Sudha Kumari, Grace J Yuen, Vinayak Viswanadham, Andrew Huang, Johnson Q. Tran, James J. Moon, Darrell J Irvine, Shiv Pillai

J Immunol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: J Immunol. 2020 Jan 1; 204(1): 49–57. Published online 2019 Nov 18. doi: 10.4049/jimmunol.1900440

PMCID:: PMC6920543

Article PDF–1.6M

Select item 558089113.

DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure

Xia Guo, Feifei Li, Zaiyan Xu, Amelia Yin, Hang Yin, Chenxiao Li, Shi-You Chen

J Lipid Res. 2017 Sep; 58(9): 1777–1784. Published online 2017 Jul 17. doi: 10.1194/jlr.M073049

PMCID:: PMC5580891

Article PDF–1.2M

Select item 489250214.

Striking immune phenotypes in diverse gene-targeted mice are driven by a copy number variant originating from a commercially available C57BL/6 strain

Vinay S Mahajan, Ezana Demissie, Hamid Mattoo, Vinay Viswanadham, Ajit Varki, Robert Morris, Shiv Pillai

Cell Rep. Author manuscript; available in PMC 2016 Jun 3.

Published in final edited form as: Cell Rep. 2016 May 31; 15(9): 1901–1909. Published online 2016 May 19. doi: 10.1016/j.celrep.2016.04.080

PMCID:: PMC4892502

Article PDF–805K

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Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2

Kei Yasuda, Kerstin Nündel, Amanda A. Watkins, Tania Dhawan, Ramon G. Bonegio, Jessalyn M. Ubellacker, Ann Marshak-Rothstein, Ian R. Rifkin

Int Immunol. 2013 May; 25(5): 295–306. Published online 2013 Jan 4. doi: 10.1093/intimm/dxs114

PMCID:: PMC3631000

Article PDF–4.7M

Select item 360233416.

Ablation of the Microglial Protein DOCK2 Reduces Amyloid Burden in a Mouse Model of Alzheimer’s Disease

Patrick J. Cimino, Yue Yang, Xianwu Li, Jake F. Hemingway, Makenzie K. Cherne, Shawn B. Khademi, Yoshinori Fukui, Kathleen S. Montine, Thomas J. Montine, C. Dirk Keene

Exp Mol Pathol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Exp Mol Pathol. 2013 Apr; 94(2): 366–371. Published online 2013 Jan 11. doi: 10.1016/j.yexmp.2013.01.002

PMCID:: PMC3602334

Article PDF–1.3M

Select item 213790217.

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate–mediated egress

César Nombela-Arrieta, Thorsten R. Mempel, Silvia F. Soriano, Irina Mazo, Matthias P. Wymann, Emilio Hirsch, Carlos Martínez-A., Yoshinori Fukui, Ulrich H. von Andrian, Jens V. Stein

J Exp Med. 2007 Mar 19; 204(3): 497–510. doi: 10.1084/jem.20061780

PMCID:: PMC2137902

Article PDF–3.0M

Select item 190003518.

N-Glycolylneuraminic Acid Deficiency in Mice: Implications for Human Biology and Evolution

Maria Hedlund, Pam Tangvoranuntakul, Hiromu Takematsu, Jeffrey M. Long, Gary D. Housley, Yasunori Kozutsumi, Akemi Suzuki, Anthony Wynshaw-Boris, Allen F. Ryan, Richard L. Gallo, Nissi Varki, Ajit Varki

Mol Cell Biol. 2007 Jun; 27(12): 4340–4346. Published online 2007 Apr 9. doi: 10.1128/MCB.00379-07

PMCID:: PMC1900035

Article PDF–584K

Select item 582029219.

The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production

Miho Ushijima, Takehito Uruno, Akihiko Nishikimi, Fumiyuki Sanematsu, Yasuhisa Kamikaseda, Kazufumi Kunimura, Daiji Sakata, Takaharu Okada, Yoshinori Fukui

Front Immunol. 2018; 9: 243. Published online 2018 Feb 16. doi: 10.3389/fimmu.2018.00243

PMCID:: PMC5820292

Article PDF–7.8M

Select item 464090420.

DOCK2 and DOCK5 Act Additively in Neutrophils To Regulate Chemotaxis, Superoxide Production, and Extracellular Trap Formation

Mayuki Watanabe, Masao Terasawa, Kei Miyano, Toyoshi Yanagihara, Takehito Uruno, Fumiyuki Sanematsu, Akihiko Nishikimi, Jean-François Côté, Hideki Sumimoto, Yoshinori Fukui

J Immunol. Author manuscript; available in PMC 2015 Nov 10.

Published in final edited form as: J Immunol. 2014 Dec 1; 193(11): 5660–5667. Published online 2014 Oct 22. doi: 10.4049/jimmunol.1400885