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Items: 1 to 20 of 82

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation
Hironori Abe, Yu-Han Yeh, Yasuhisa Munakata, Kei-Ichiro Ishiguro, Paul R. Andreassen, Satoshi H. Namekawa
Nat Commun. 2022; 13: 7212. Published online 2022 Nov 28. doi: 10.1038/s41467-022-34295-5
PMCID:
PMC9705562
ArticlePDF–8.5M
3.
SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates
Tushar Warrier, Chadi El Farran, Yingying Zeng, Benedict Shao Quan Ho, Qiuye Bao, Zi Hao Zheng, Xuezhi Bi, Huck Hui Ng, Derrick Sek Tong Ong, Justin Jang Hann Chu, Amartya Sanyal, Melissa Jane Fullwood, James J Collins, Hu Li, Jian Xu, Yuin-Han Loh
Nucleic Acids Res. 2022 Jul 22; 50(13): 7326–7349. Published online 2022 Jul 1. doi: 10.1093/nar/gkac531
PMCID:
PMC9303280
ArticlePDF–5.7M
4.
SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers
Amandine Barral, Gabrielle Pozo, Lucas Ducrot, Giorgio L. Papadopoulos, Sandrine Sauzet, Andrew J. Oldfield, Giacomo Cavalli, Jérôme Déjardin
Mol Cell. 2022 Feb 17; 82(4): 816–832.e12. doi: 10.1016/j.molcel.2021.12.037
PMCID:
PMC8860380
Article
5.
The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis
Ee-Chun Cheng, Chia-Ling Hsieh, Na Liu, Jianquan Wang, Mei Zhong, Taiping Chen, En Li, Haifan Lin
Cell Rep. Author manuscript; available in PMC 2021 Oct 13.
Published in final edited form as: Cell Rep. 2021 Jan 5; 34(1): 108575. doi: 10.1016/j.celrep.2020.108575
PMCID:
PMC8513770
ArticlePDF–2.4M
6.
The H3K9 Methylation Writer SETDB1 and Its Reader MPP8 Cooperate to Silence Satellite DNA Repeats in Mouse Embryonic Stem Cells
Paola Cruz-Tapias, Philippe Robin, Julien Pontis, Laurence Del Maestro, Slimane Ait-Si-Ali
Genes (Basel) 2019 Oct; 10(10): 750. Published online 2019 Sep 25. doi: 10.3390/genes10100750
PMCID:
PMC6826936
ArticlePDF–2.2M
7.
SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres
Mathilde Gauchier, Sophie Kan, Amandine Barral, Sandrine Sauzet, Eneritz Agirre, Erin Bonnell, Nehmé Saksouk, Teresa K. Barth, Satoru Ide, Serge Urbach, Raymund J. Wellinger, Reini F. Luco, Axel Imhof, Jérôme Déjardin
Sci Adv. 2019 May; 5(5): eaav3673. Published online 2019 May 8. doi: 10.1126/sciadv.aav3673
PMCID:
PMC6506250
ArticlePDF–1.5M
8.
A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing
Masaki Kato, Keiko Takemoto, Yoichi Shinkai
Nat Commun. 2018; 9: 1683. Published online 2018 Apr 27. doi: 10.1038/s41467-018-04132-9
PMCID:
PMC5923290
ArticlePDF–1.7M
9.
Kmt1e regulates a large neuron-specific topological chromatin domain
Yan Jiang, Yong-Hwee Eddie Loh, Prashanth Rajarajan, Teruyoshi Hirayama, Will Liao, Bibi S. Kassim, Behnam Javidfar, Brigham J Hartley, Lisa Kleofas, Royce B Park, Benoit Labonte, Seok-Man Ho, Sandhya Chandrasekaran, Catherine Do, Brianna R Ramirez, Cyril J. Peter, TCW Julia, Brian M Safaie, Hirofumi Morishita, Panos Roussos, Eric J Nestler, Anne Schaefer, Benjamin Tycko, Kristen J Brennand, Takeshi Yagi, Li Shen, Schahram Akbarian
Nat Genet. Author manuscript; available in PMC 2018 Jan 3.
Published in final edited form as: Nat Genet. 2017 Aug; 49(8): 1239–1250. Published online 2017 Jul 3. doi: 10.1038/ng.3906
PMCID:
PMC5560095
ArticlePDF–2.7M
10.
Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse
Jeesun Kim, Hongbo Zhao, Jiameng Dan, Soojin Kim, Swanand Hardikar, Debra Hollowell, Kevin Lin, Yue Lu, Yoko Takata, Jianjun Shen, Taiping Chen
PLoS Genet. 2016 Apr; 12(4): e1005970. Published online 2016 Apr 12. doi: 10.1371/journal.pgen.1005970
PMCID:
PMC4829257
ArticlePDF–9.7M
11.
SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells
Qi Fei, Xiaoqin Yang, Hua Jiang, Qian Wang, Yanyan Yu, Yiling Yu, Wei Yi, Shaolian Zhou, Taiping Chen, Chris Lu, Peter Atadja, Xiaole Shirley Liu, En Li, Yong Zhang, Jianyong Shou
Genome Res. 2015 Sep; 25(9): 1325–1335. doi: 10.1101/gr.177576.114
PMCID:
PMC4561491
ArticlePDF–543K
12.
hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells
Peter J. Thompson, Vered Dulberg, Kyung-Mee Moon, Leonard J. Foster, Carol Chen, Mohammad M. Karimi, Matthew C. Lorincz
PLoS Genet. 2015 Jan; 11(1): e1004933. Published online 2015 Jan 22. doi: 10.1371/journal.pgen.1004933
Correction in:
PLoS Genet. 2016 Oct; 12(10): e1006390.
PMCID:
PMC4303303
ArticlePDF–1.7M
13.
Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1
Danny Leung, Tingting Du, Ulrich Wagner, Wei Xie, Ah Young Lee, Preeti Goyal, Yujing Li, Keith E. Szulwach, Peng Jin, Matthew C. Lorincz, Bing Ren
Proc Natl Acad Sci U S A. 2014 May 6; 111(18): 6690–6695. Published online 2014 Apr 22. doi: 10.1073/pnas.1322273111
PMCID:
PMC4020067
ArticlePDF–1.2M
14.
The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice
J An, X Zhang, J Qin, Y Wan, Y Hu, T Liu, J Li, W Dong, E Du, C Pan, W Zeng
Cell Death Dis. 2014 Apr; 5(4): e1196. Published online 2014 Apr 24. doi: 10.1038/cddis.2014.171
PMCID:
PMC4001319
ArticlePDF–3.8M
15.
ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development
Kevin A. Lawson, Colin J. Teteak, Jidi Gao, Ning Li, Jacques Hacquebord, Andrew Ghatan, Anna Zielinska-Kwiatkowska, Guangchun Song, Howard A. Chansky, Liu Yang
FEBS Lett. Author manuscript; available in PMC 2014 Dec 11.
Published in final edited form as: FEBS Lett. 2013 Dec 11; 587(24): 3961–3967. Published online 2013 Nov 1. doi: 10.1016/j.febslet.2013.10.028
PMCID:
PMC3947621
ArticlePDF–2.0M
16.
Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B
Yan Jiang, Mira Jakovcevski, Rahul Bharadwaj, Caroline Connor, Frederick A. Schroeder, Cong L. Lin, Juerg Straubhaar, Gilles Martin, Schahram Akbarian
J Neurosci. 2010 May 26; 30(21): 7152–7167. doi: 10.1523/JNEUROSCI.1314-10.2010
PMCID:
PMC2893142
ArticlePDF–4.5M
17.
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
Steve Bilodeau, Michael H. Kagey, Garrett M. Frampton, Peter B. Rahl, Richard A. Young
Genes Dev. 2009 Nov 1; 23(21): 2484–2489. doi: 10.1101/gad.1837309
PMCID:
PMC2779743
ArticlePDF–667K
18.
Cell-type differential targeting of SETDB1 prevents aberrant CTCF binding, chromatin looping, and cis-regulatory interactions
Phoebe Lut Fei Tam, Ming Fung Cheung, Lu Yan Chan, Danny Leung
Nat Commun. 2024; 15: 15. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44578-0
PMCID:
PMC10762014
ArticlePDF–2.9M
19.
Histone H3K9 Methyltransferase SETDB1 Augments Invadopodia Formation to Promote Tumor Metastasis
Shuhei Ueshima, Jia Fang
Oncogene. Author manuscript; available in PMC 2022 Dec 30.
Published in final edited form as: Oncogene. 2022 Jun; 41(24): 3370–3380. Published online 2022 May 11. doi: 10.1038/s41388-022-02345-3
PMCID:
PMC9801494
ArticlePDF–5.5M
20.
Temporarily Epigenetic Repression in Bergmann Glia Regulates the Migration of Granule Cells
Shaoxuan Chen, Kunkun Zhang, Boxin Zhang, Mengyun Jiang, Xue Zhang, Yi Guo, Yingying Yu, Tianyu Qin, Hongda Li, Qiang Chen, Zhiyu Cai, Site Luo, Yi Huang, Jin Hu, Wei Mo
Adv Sci (Weinh) 2021 May; 8(10): 2003164. Published online 2021 Mar 22. doi: 10.1002/advs.202003164
PMCID:
PMC8132163
ArticlePDF–7.7M

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