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Items: 1 to 20 of 148

1.
Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes
Yi Ching Esther Wan, Tsz Chui Sophia Leung, Dongbo Ding, Xulun Sun, Jiaxian Liu, Lina Zhu, Tze Zhen Evangeline Kang, Du Yang, Yuchen Zhang, Jitian Zhang, Chengmin Qian, Michael Shing Yan Huen, Qing Li, Maggie Zi Ying Chow, Zongli Zheng, Junhong Han, Ajay Goel, Xin Wang, Toyotaka Ishibashi, Kui Ming Chan
Signal Transduct Target Ther. 2020; 5: 27. Published online 2020 Mar 6. doi: 10.1038/s41392-020-0131-0
PMCID:
PMC7060176
ArticlePDF–1.4M
2.
Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate
Gilad Fuchs, Dror Hollander, Yoav Voichek, Gil Ast, Moshe Oren
Genome Res. 2014 Oct; 24(10): 1572–1583. doi: 10.1101/gr.176487.114
PMCID:
PMC4199367
AbstractArticlePDF–1.9M
3.
H2B monoubiquitylation is a 5′-enriched active transcription mark and correlates with exon–intron structure in human cells
Inkyung Jung, Seung-Kyoon Kim, Mirang Kim, Yong-Mahn Han, Yong Sung Kim, Dongsup Kim, Daeyoup Lee
Genome Res. 2012 Jun; 22(6): 1026–1035. doi: 10.1101/gr.120634.111
PMCID:
PMC3371706
AbstractArticlePDF–1.7M
4.
Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors
Yasuyo Urasaki, Linda Heath, C. Wilson Xu
PLoS One. 2012; 7(5): e36775. Published online 2012 May 16. doi: 10.1371/journal.pone.0036775
PMCID:
PMC3353945
AbstractArticlePDF–1.6M
5.
The H2BG53D oncohistone directly upregulates ANXA3 transcription and enhances cell migration in pancreatic ductal adenocarcinoma
Yi Ching Esther Wan, Jiaxian Liu, Lina Zhu, Tze Zhen Evangeline Kang, Xiaoxuan Zhu, John Lis, Toyotaka Ishibashi, Charles G. Danko, Xin Wang, Kui Ming Chan
Signal Transduct Target Ther. 2020; 5: 106. Published online 2020 Jun 30. doi: 10.1038/s41392-020-00219-2
PMCID:
PMC7326972
ArticlePDF–1.1M
6.
Top-down and Middle-down Protein Analysis Reveals that Intact and Clipped Human Histones Differ in Post-translational Modification Patterns
Andrey Tvardovskiy, Krzysztof Wrzesinski, Simone Sidoli, Stephen J. Fey, Adelina Rogowska-Wrzesinska, Ole N. Jensen
Mol Cell Proteomics. 2015 Dec; 14(12): 3142–3153. Published online 2015 Sep 30. doi: 10.1074/mcp.M115.048975
PMCID:
PMC4762630
AbstractArticlePDF–1.9M
7.
Expressing Status and Correlation of ARID1A and Histone H2B on Breast Cancer
Yan Wu, Yan Gu, Shanyu Guo, Qiancheng Dai, Wei Zhang
Biomed Res Int. 2016; 2016: 7593787. Published online 2016 Jan 21. doi: 10.1155/2016/7593787
PMCID:
PMC4745880
AbstractArticlePDF–2.8M
8.
Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer
Marsela Braunstein, Linda Liao, Nicola Lyttle, Nazleen Lobo, Karen J. Taylor, Paul M. Krzyzanowski, Irina Kalatskaya, Cindy Q. Yao, Lincoln D. Stein, Paul C. Boutros, Christopher J. Twelves, Richard Marcellus, John M. S. Bartlett, Melanie Spears
Breast Cancer Res. 2016; 18: 16. Published online 2016 Feb 6. doi: 10.1186/s13058-016-0676-6
PMCID:
PMC4744406
AbstractArticlePDF–1.8M
9.
Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin
Matthew T. Holt, Yael David, Sam Pollock, Zhanyun Tang, Jongcheol Jeon, Jaehoon Kim, Robert G. Roeder, Tom W. Muir
Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33): 10365–10370. Published online 2015 Aug 3. doi: 10.1073/pnas.1504483112
PMCID:
PMC4547310
AbstractArticlePDF–1.4M
10.
Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity
Andreas K. Hock, Arnaud M. Vigneron, Karen H. Vousden
J Biol Chem. 2014 Dec 12; 289(50): 34862–34870. Published online 2014 Oct 21. doi: 10.1074/jbc.M114.589267
PMCID:
PMC4263885
AbstractArticlePDF–2.2M
11.
The Oncogenic Polycomb Histone Methyltransferase EZH2 Methylates Lysine 120 on Histone H2B and Competes Ubiquitination
Masaharu Kogure, Masashi Takawa, Vassiliki Saloura, Kenbun Sone, Lianhua Piao, Koji Ueda, Reem Ibrahim, Tatsuhiko Tsunoda, Masanori Sugiyama, Yutaka Atomi, Yusuke Nakamura, Ryuji Hamamoto
Neoplasia. 2013 Nov; 15(11): 1251–1261. doi: 10.1593/neo.131436
PMCID:
PMC3858897
AbstractArticlePDF–4.1M
12.
Core Histones H2B and H4 Are Mobilized during Infection with Herpes Simplex Virus 1
Kristen L. Conn, Michael J. Hendzel, Luis M. Schang
J Virol. 2011 Dec; 85(24): 13234–13252. doi: 10.1128/JVI.06038-11
PMCID:
PMC3233158
AbstractArticlePDF–3.9M
13.
HIV-Infected Patients: Cross Site-Specific Hydrolysis of H2a and H2b Histones and Myelin Basic Protein with Antibodies against These Three Proteins
Svetlana V. Baranova, Pavel S. Dmitrienok, Valentina N. Buneva, Georgy A. Nevinsky
Biomolecules. 2020 Nov; 10(11): 1501. Published online 2020 Oct 30. doi: 10.3390/biom10111501
PMCID:
PMC7693679
AbstractArticlePDF–10M
14.
Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing
Yan Huang, Lu Sun, Leonidas Pierrakeas, Linchang Dai, Lu Pan, Ed Luk, Zheng Zhou
Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3543–3550. Published online 2020 Jan 30. doi: 10.1073/pnas.1914313117
PMCID:
PMC7035559
AbstractArticlePDF–1.9M
15.
let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery
Ambra Spolverini, Gilad Fuchs, Débora Rosa Bublik, Moshe Oren
Oncogene. Author manuscript; available in PMC 2017 Dec 12.
Published in final edited form as: Oncogene. 2017 Oct 19; 36(42): 5819–5828. Published online 2017 Jun 12. doi: 10.1038/onc.2017.187
PMCID:
PMC5600258
AbstractArticlePDF–1.9M
16.
Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition
Siming Zhao, Stefania Bellone, Salvatore Lopez, Durga Thakral, Carlton Schwab, Diana P. English, Jonathan Black, Emiliano Cocco, Jungmin Choi, Luca Zammataro, Federica Predolini, Elena Bonazzoli, Mark Bi, Natalia Buza, Pei Hui, Serena Wong, Maysa Abu-Khalaf, Antonella Ravaggi, Eliana Bignotti, Elisabetta Bandiera, Chiara Romani, Paola Todeschini, Renata Tassi, Laura Zanotti, Franco Odicino, Sergio Pecorelli, Carla Donzelli, Laura Ardighieri, Fabio Facchetti, Marcella Falchetti, Dan-Arin Silasi, Elena Ratner, Masoud Azodi, Peter E. Schwartz, Shrikant Mane, Roberto Angioli, Corrado Terranova, Charles Matthew Quick, Babak Edraki, Kaya Bilgüvar, Moses Lee, Murim Choi, Amy L. Stiegler, Titus J. Boggon, Joseph Schlessinger, Richard P. Lifton, Alessandro D. Santin
Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12238–12243. Published online 2016 Oct 10. doi: 10.1073/pnas.1614120113
PMCID:
PMC5087050
AbstractArticlePDF–935K
17.
Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation
Jasmine Li, Kristine Hardy, Chan Phetsouphanh, Wen Juan Tu, Elissa L. Sutcliffe, Robert McCuaig, Christopher R. Sutton, Anjum Zafar, C. Mee Ling Munier, John J. Zaunders, Yin Xu, Angelo Theodoratos, Abel Tan, Pek Siew Lim, Tobias Knaute, Antonia Masch, Johannes Zerweck, Vedran Brezar, Peter J. Milburn, Jenny Dunn, Marco G. Casarotto, Stephen J. Turner, Nabila Seddiki, Anthony D. Kelleher, Sudha Rao
J Cell Sci. 2016 Jun 15; 129(12): 2448–2461. doi: 10.1242/jcs.181248
PMCID:
PMC4920249
AbstractArticle
18.
A novel histone exchange factor, protein phosphatase 2Cγ, mediates the exchange and dephosphorylation of H2A–H2B
Hiroshi Kimura, Nanako Takizawa, Eric Allemand, Tetsuya Hori, Francisco J. Iborra, Naohito Nozaki, Michiko Muraki, Masatoshi Hagiwara, Adrian R. Krainer, Tatsuo Fukagawa, Katsuya Okawa
J Cell Biol. 2006 Nov 6; 175(3): 389–400. doi: 10.1083/jcb.200608001
PMCID:
PMC2064517
AbstractArticlePDF–3.4M
19.
Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes
Dimitar Angelov, Vladimir A Bondarenko, Sébastien Almagro, Hervé Menoni, Fabien Mongélard, Fabienne Hans, Flore Mietton, Vasily M Studitsky, Ali Hamiche, Stefan Dimitrov, Philippe Bouvet
EMBO J. 2006 Apr 19; 25(8): 1669–1679. Published online 2006 Apr 6. doi: 10.1038/sj.emboj.7601046
PMCID:
PMC1440837
AbstractArticlePDF–316K
20.
Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane
Islam U. Khan, Reidar Wallin, Radhey S. Gupta, Gary M. Kammer
Proc Natl Acad Sci U S A. 1998 Sep 1; 95(18): 10425–10430. doi: 10.1073/pnas.95.18.10425
PMCID:
PMC27910
AbstractArticlePDF–283K

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