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Items: 1 to 20 of 139

1.
New insights into the role of VKORC1 polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model
Karine Rodríguez-Fernández, Gledys Reynaldo-Fernández, Stephanie Reyes-González, Camila de las Barreras, Leyanis Rodríguez-Vera, Cornelis Vlaar, Jean-Christophe M. Monbaliu, Torsten Stelzer, Jorge Duconge, Victor Mangas-Sanjuan
Biomed Pharmacother. Author manuscript; available in PMC 2024 Feb 9.
Published in final edited form as: Biomed Pharmacother. 2024 Jan; 170: 115977. Published online 2023 Dec 6. doi: 10.1016/j.biopha.2023.115977
PMCID:
PMC10853672
AbstractArticlePDF–883K
2.
Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state
Shuang Li, Jie Sun, Shixuan Liu, Fengbo Zhou, Michael L. Gross, Weikai Li
Blood Adv. 2023 May 23; 7(10): 2271–2282. Published online 2022 Dec 14. doi: 10.1182/bloodadvances.2021006876
PMCID:
PMC10225482
AbstractArticlePDF–3.2M
3.
Association of VKORC1 polymorphisms and major bleedings in patients who are treated with vitamin K antagonists
D. Max van Heteren, Willem M. Lijfering, Felix J. M. van der Meer, Pieter H. Reitsma, Jesse J. Swen, Mettine H. A. Bos, Nienke van Rein
J Intern Med. 2023 Jan; 293(1): 124–127. Published online 2022 Sep 20. doi: 10.1111/joim.13569
PMCID:
PMC10087804
ArticlePDF–192K
4.
Variation in VKORC1 Is Associated with Vascular Dementia
Jure Mur, Daniel L. McCartney, Daniel I. Chasman, Peter M. Visscher, Graciela Muniz-Terrera, Simon R. Cox, Tom C. Russ, Riccardo E. Marioni
J Alzheimers Dis. 2021; 80(3): 1329–1337. Prepublished online 2021 Feb 26. Published online 2021 Apr 6. doi: 10.3233/JAD-201256
PMCID:
PMC8150662
AbstractArticlePDF–207K
5.
Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation
Shixuan Liu, Shuang Li, Guomin Shen, Narayanasami Sukumar, Andrzej M. Krezel, Weikai Li
Science. Author manuscript; available in PMC 2021 Mar 10.
Published in final edited form as: Science. 2021 Jan 1; 371(6524): eabc5667. Published online 2020 Nov 5. doi: 10.1126/science.abc5667
PMCID:
PMC7946407
AbstractArticlePDF–1.6M
6.
Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact
Melissa A Chiasson, Nathan J Rollins, Jason J Stephany, Katherine A Sitko, Kenneth A Matreyek, Marta Verby, Song Sun, Frederick P Roth, Daniel DeSloover, Debora S Marks, Allan E Rettie, Douglas M Fowler
eLife. 2020; 9: e58026. Published online 2020 Sep 1. doi: 10.7554/eLife.58026
PMCID:
PMC7462613
AbstractArticlePDF–3.9M
7.
Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity
Rob Janssen, Jona Walk
Med Hypotheses. 2020 Nov; 144: 110218. Published online 2020 Aug 25. doi: 10.1016/j.mehy.2020.110218
PMCID:
PMC7446614
AbstractArticlePDF–567K
8.
The effect of the VKORC1 promoter variant on warfarin responsiveness in the Saudi WArfarin Pharmacogenetic (SWAP) cohort
Maha Al Ammari, Mohammed AlBalwi, Khizra Sultana, Ibrahim B. Alabdulkareem, Bader Almuzzaini, Nada S. Almakhlafi, Mohammed Aldrees, Jahad Alghamdi
Sci Rep. 2020; 10: 11613. Published online 2020 Jul 15. doi: 10.1038/s41598-020-68519-9
PMCID:
PMC7363835
AbstractArticlePDF–1.0M
9.
VKORC1-1639A allele influences warfarin maintenance dosage among Blacks receiving warfarin anticoagulation: a retrospective cohort study
Fatima Donia Mili, Tenecia Allen, Paula Weinstein Wadell, W Craig Hooper, Christine De Staercke, Christopher J Bean, Cathy Lally, Harland Austin, Nanette K Wenger
Future Cardiol. Author manuscript; available in PMC 2019 Sep 5.
Published in final edited form as: Future Cardiol. 2018 Jan; 14(1): 15–26. Published online 2017 Dec 8. doi: 10.2217/fca-2017-0025
PMCID:
PMC6727961
AbstractArticlePDF–122K
10.
Genetic Polymorphism of VKORC1-1639 in Children With Intracranial Hemorrhage Due to Vitamin K Deficiency
Uğur Berber, Mehmet Akif Özdemir, Ekrem Unal, Serpil Taheri, Serkan Yildiz, Keziban Korkmaz Bayramov, Yunus Güler, Hüseyin Per
Clin Appl Thromb Hemost. 2018 Dec; 24(9 Suppl): 89S–93S. Published online 2018 Aug 13. doi: 10.1177/1076029618792302
PMCID:
PMC6714858
AbstractArticlePDF–159K
11.
Is there any association between osteoporotic vertebral fracture and vitamin K epoxide reductase complex subunit-1 polymorphism in Turkish society? A pilot study
Merih Ozgen, Didem Turgut Cosan, Fulya Doganer, Ahu Soyocak, Onur Armagan, Selen Kuzgun, Ayse Merve Aydogan, Hasan Veysi Gunes, Irfan Degirmenci, Fezan Mutlu
Clinics (Sao Paulo) 2019; 74: e739. Published online 2019 Mar 5. doi: 10.6061/clinics/2019/e739
PMCID:
PMC6399659
AbstractArticlePDF–194K
12.
Value of VKORC1 (−1639G>A) rs9923231 genotyping in predicting warfarin dose: A replication study in South Indian population
S. Harikrishnan, Linda Koshy, Ram Subramanian, G. Sanjay, C.P. Vineeth, A. Jayakumaran Nair, G.M. Nair, P.R. Sudhakaran
Indian Heart J. 2018 Dec; 70(Suppl 3): S110–S115. Published online 2018 Jul 19. doi: 10.1016/j.ihj.2018.07.006
PMCID:
PMC6310074
AbstractArticlePDF–712K
13.
G-1639A but Not C1173T VKORC1 Gene Polymorphism Is Related to Ischemic Stroke and Its Various Risk Factors in Ukrainian Population
Yevhen I. Dubovyk, Viktoriia Yu. Harbuzova, Alexander V. Ataman
Biomed Res Int. 2016; 2016: 1298198. Published online 2016 Sep 15. doi: 10.1155/2016/1298198
PMCID:
PMC5040782
AbstractArticlePDF–552K
14.
Effects of VKORC1 Genetic Polymorphisms on Warfarin Maintenance Dose Requirement in a Chinese Han Population
Xiaojuan Yan, Feng Yang, Hanyun Zhou, Hongshen Zhang, Jianfei Liu, Kezhong Ma, Yi Li, Jun Zhu, Jianqiang Ding
Med Sci Monit. 2015; 21: 3577–3584. Published online 2015 Nov 19. doi: 10.12659/MSM.894414
PMCID:
PMC4657763
AbstractArticlePDF–343K
15.
MEASURES OF EXPOSURE IMPACT GENETIC ASSOCIATION STUDIES: AN EXAMPLE IN VITAMIN K LEVELS AND VKORC1
DANA C. CRAWFORD, KRISTIN BROWN-GENTRY, MARK J. RIEDER
Pac Symp Biocomput. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Pac Symp Biocomput. 2015 : 161–170.
PMCID:
PMC4299921
AbstractArticlePDF–1.0M
16.
Warfarin Dosage Response Related Pharmacogenetics in Chinese Population
Siyue Li, Yuangao Zou, Xia Wang, Xunbei Huang, Yong Sun, Yuqing Wang, Li Dong, Hong Jiang
PLoS One. 2015; 10(1): e0116463. Published online 2015 Jan 16. doi: 10.1371/journal.pone.0116463
PMCID:
PMC4296935
AbstractArticlePDF–570K
17.
A New Nested Allele-Specific Multiplex Polymerase Chain Reaction Method for Haplotyping of VKORC1 Gene to Predict Warfarin Sensitivity
Yung An Chua, Wan Zaidah Abdullah, Zukurnai Yusof, Siew Hua Gan
Biomed Res Int. 2014; 2014: 316310. Published online 2014 Mar 30. doi: 10.1155/2014/316310
PMCID:
PMC3985146
AbstractArticlePDF–755K
18.
Association of Functional VKORC1 Promoter Polymorphism with Occurrence and Clinical Aspects of Ischemic Stroke in a Greek Population
Georgia Ragia, Stella Marousi, John Ellul, Vangelis G. Manolopoulos, Anna Tavridou
Dis Markers. 2013; 35(6): 641–646. Published online 2013 Oct 31. doi: 10.1155/2013/769574
PMCID:
PMC3832979
AbstractArticlePDF–529K
19.
Evaluation of warfarin resistance using TALENs-mediated vitamin K epoxide reductase knockout HEK293 cells
Jian-Ke Tie, Da-Yun Jin, Kevin Tie, Darrel W. Stafford
J Thromb Haemost. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: J Thromb Haemost. 2013 Aug; 11(8): 1556–1564. doi: 10.1111/jth.12306
PMCID:
PMC3745541
AbstractArticlePDF–1.5M
20.
Relationship between VKORC1 single nucleotide polymorphism 1173C>T, bone mineral density & carotid intima-media thickness
Daniela Fodor, Cosmina Bondor, Adriana Albu, Radu Popp, Ioan Victor Pop, Laura Poanta
Indian J Med Res. 2013 Apr; 137(4): 734–741.
PMCID:
PMC3724254
AbstractArticlePDF–357K

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