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Select item 103932411.

Loss of ZNF148 enhances insulin secretion in human pancreatic β cells

Eleonora de Klerk, Yini Xiao, Christopher H. Emfinger, Mark P. Keller, David I. Berrios, Valentina Loconte, Axel A. Ekman, Kate L. White, Rebecca L. Cardone, Richard G. Kibbey, Alan D. Attie, Matthias Hebrok

JCI Insight. 2023 Jun 8; 8(11): e157572. Published online 2023 Jun 8. doi: 10.1172/jci.insight.157572

PMCID:: PMC10393241

Abstract Article PDF–13M

Select item 55577522.

Transcription factor ZNF148 is a negative regulator of human muscle differentiation

Jesse Bakke, William C. Wright, Anthony E. Zamora, Su Sien Ong, Yue-Ming Wang, Jessica D. Hoyer, Christopher T. Brewer, Paul G. Thomas, Taosheng Chen

Sci Rep. 2017; 7: 8138. Published online 2017 Aug 15. doi: 10.1038/s41598-017-08267-5

PMCID:: PMC5557752

Abstract Article PDF–5.5M

Select item 52287063.

ZNF148 modulates TOP2A expression and cell proliferation via ceRNA regulatory mechanism in colorectal cancer

Xian Hua Gao, Juan Li, Yan Liu, Qi Zhi Liu, Li Qiang Hao, Lian Jie Liu, Wei Zhang

Medicine (Baltimore) 2017 Jan; 96(1): e5845. Published online 2017 Jan 10. doi: 10.1097/MD.0000000000005845

PMCID:: PMC5228706

Abstract Article PDF–861K

Select item 51553774.

Truncating de novo mutations in the Krüppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms

Servi J. C. Stevens, Anthonie J. van Essen, Conny M. A. van Ravenswaaij, Abdallah F. Elias, Jaclyn A. Haven, Stefan H. Lelieveld, Rolph Pfundt, Willy M. Nillesen, Helger G. Yntema, Kees van Roozendaal, Alexander P. Stegmann, Christian Gilissen, Han G. Brunner

Genome Med. 2016; 8: 131. Published online 2016 Dec 13. doi: 10.1186/s13073-016-0386-9

PMCID:: PMC5155377

Abstract Article PDF–781K

Select item 31040545.

ZBP-89 reduces the cell death threshold in hepatocellular carcinoma cells by increasing caspase-6 and S phase cell-cycle arrest

George G Chen, Ursula PF Chan, Long-Chuan Bai, King Yip Fung, Art Tessier, Ann KY To, Juanita L Merchant, Paul BS Lai

Cancer Lett. Author manuscript; available in PMC 2011 May 30.

Published in final edited form as: Cancer Lett. 2009 Sep 28; 283(1): 52–58. Published online 2009 Apr 11. doi: 10.1016/j.canlet.2009.03.024

PMCID:: PMC3104054

Abstract Article PDF–273K

Select item 3603036.

The ht beta gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expression.

Y Wang, J A Kobori, L Hood

Mol Cell Biol. 1993 Sep; 13(9): 5691–5701. doi: 10.1128/mcb.13.9.5691

PMCID:: PMC360303

Summary Page Browse PDF–2.3M

Select item 104011317.

Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem‐like cells microenvironment

Shan Cheng, Liang Liu, Delin Wang, Yongdong Li, Suwen Li, Jiaqi Yuan, Shilu Huang, Zhipeng Xu, Bin Jia, Zhe Li, Jun Dong

CNS Neurosci Ther. 2023 Sep; 29(9): 2690–2704. Published online 2023 Apr 17. doi: 10.1111/cns.14213

PMCID:: PMC10401131

Abstract Article PDF–3.8M

Select item 54141798.

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Tongwu Zhang, Jason W. Hoskins, Jiyeon Choi, Younghun Han, Mingfeng Zhang, Janelle Thomas, Michael Kovacs, Irene Collins, Marta Dzyadyk, Abbey Thompson, Maura O'Neill, Sudipto Das, Qi Lan, Roelof Koster, PanScan Consortium, TRICL Consortium, GenoMEL Consortium, Rachael S. Stolzenberg-Solomon, Peter Kraft, Brian M. Wolpin, Pascal W. T. C. Jansen, Sara Olson, Katherine A. McGlynn, Peter A. Kanetsky, Nilanjan Chatterjee, Jennifer H. Barrett, Alison M. Dunning, John C. Taylor, Julia A. Newton-Bishop, D. Timothy Bishop, Thorkell Andresson, Gloria M. Petersen, Christopher I. Amos, Mark M. Iles, Katherine L. Nathanson, Maria Teresa Landi, Michiel Vermeulen, Kevin M. Brown, Laufey T. Amundadottir

Nat Commun. 2017; 8: 15034. Published online 2017 Apr 27. doi: 10.1038/ncomms15034

Correction in:: Nat Commun. 2018; 9: 16159.

PMCID:: PMC5414179

Abstract Article PDF–1.3M

Select item 41600279.

Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma

Cai Guo Ye, George G Chen, Rocky LK Ho, Juanita L Merchant, Ming-Liang He, Paul BS Lai

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Sep 10.

Published in final edited form as: Biochim Biophys Acta. 2013 Dec; 1833(12): 2970–2979. Published online 2013 Aug 13. doi: 10.1016/j.bbamcr.2013.08.001

PMCID:: PMC4160027

Abstract Article PDF–2.0M

Select item 329338110.

Interaction between ZBP-89 and p53 mutants and its contribution to effects of HDACi on hepatocellular carcinoma

Chris ZY Zhang, George G Chen, Juanita L Merchant, Paul BS Lai

Cell Cycle. 2012 Jan 15; 11(2): 322–334. Published online 2012 Jan 15. doi: 10.4161/cc.11.2.18758

PMCID:: PMC3293381

Abstract Article PDF–11M

Select item 267896611.

NF-κB AND ZBP-89 REGULATE MMP-3 EXPRESSION VIA A POLYMORPHIC SITE IN THE PROMOTER

Ruth C. Borghaei, Grzegorz Gorski, Masoud Javadi, Mariah Chambers

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Biochem Biophys Res Commun. 2009 May 1; 382(2): 269–273. Published online 2009 Mar 9. doi: 10.1016/j.bbrc.2009.03.002

PMCID:: PMC2678966

Abstract Article PDF–693K

Select item 186814012.

Mutation of p53 in Recurrent Hepatocellular Carcinoma and Its Association with the Expression of ZBP-89

George G. Chen, Juanita L. Merchant, Paul B. S. Lai, Rocky L. K. Ho, Xu Hu, Morihiro Okada, Sheng F. Huang, Albert K. K. Chui, David J. Law, Yong G. Li, Wan Y. Lau, Arthur K. C. Li

Am J Pathol. 2003 Jun; 162(6): 1823–1829. doi: 10.1016/S0002-9440(10)64317-9

PMCID:: PMC1868140

Abstract Article PDF–528K

Select item 139068713.

An isoform of ZBP-89 predisposes the colon to colitis

David J. Law, Edwin M. Labut, Rachael D. Adams, Juanita L. Merchant

Nucleic Acids Res. 2006; 34(5): 1342–1350. Published online 2006 Mar 3. doi: 10.1093/nar/gkl022

PMCID:: PMC1390687

Abstract Article PDF–525K

Select item 23166614.

ZBP-89, a Krüppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter.

J L Merchant, G R Iyer, B R Taylor, J R Kitchen, E R Mortensen, Z Wang, R J Flintoft, J B Michel, R Bassel-Duby

Mol Cell Biol. 1996 Dec; 16(12): 6644–6653. doi: 10.1128/mcb.16.12.6644

PMCID:: PMC231666

Summary PDF–465K

Select item 8714015.

ZBP-89 Promotes Growth Arrest through Stabilization of p53

Longchuan Bai, Juanita L. Merchant

Mol Cell Biol. 2001 Jul; 21(14): 4670–4683. doi: 10.1128/MCB.21.14.4670-4683.2001

PMCID:: PMC87140

Abstract Article PDF–1.9M

Select item 722690816.

ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway

Nuozhou Wang, Ming-yue Li, Yi Liu, Jianqing Yu, Jianwei Ren, Zhiyuan Zheng, Shanshan Wang, Shucai Yang, Sheng-li Yang, Li-ping Liu, Bao-guang Hu, Charing CN Chong, Juanita L Merchant, Paul BS Lai, George Gong Chen

Cancer Lett. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Cancer Lett. 2020 Mar 1; 472: 70–80. Published online 2019 Dec 23. doi: 10.1016/j.canlet.2019.12.026

PMCID:: PMC7226908

Abstract Article PDF–1.2M

Select item 715681917.

Upregulation of ZNF148 in SDHB‐deficient gastrointestinal stromal tumor potentiates Forkhead box M1‐mediated transcription and promotes tumor cell invasion

Xiaodong Gao, Chunmin Ma, Xiangwei Sun, Qin Zhao, Yong Fang, Yuhui Jiang, Kuntang Shen, Xian Shen

Cancer Sci. 2020 Apr; 111(4): 1266–1278. Published online 2020 Mar 16. doi: 10.1111/cas.14348

PMCID:: PMC7156819

Abstract Article PDF–1.9M

Select item 589932918.

ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells

Xia Kong, Pin Xu, Wei-Jie Cai, Huai-Gao Wang, Bin-Bin Li, Guo-Liang Huang, Zhi-Wei He, George Chen, Cai-Guo Ye

BMC Cancer. 2018; 18: 419. Published online 2018 Apr 13. doi: 10.1186/s12885-018-4349-y

PMCID:: PMC5899329

Abstract Article PDF–2.9M

Select item 537947419.

Transcription factor ZBP-89 drives a feedforward loop of β-catenin expression in colorectal cancer

Bryan E. Essien, Sinju Sundaresan, Ramon Ocadiz-Ruiz, Aaron Chavis, Amy C. Tsao, Arthur J. Tessier, Michael M Hayes, Amanda Photenhauer, Milena Saqui-Salces, Anthony J. Kang, Yatrik M. Shah, Balazs Györffy, Juanita L. Merchant

Cancer Res. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Cancer Res. 2016 Dec 1; 76(23): 6877–6887. Published online 2016 Oct 10. doi: 10.1158/0008-5472.CAN-15-3150

PMCID:: PMC5379474

Abstract Article PDF–2.2M

Select item 431144620.

ZBP-89 reduces histone deacetylase 3 by degrading IkappaB in the presence of Pin1

Cai Guo Ye, Liping Liu, George G Chen, Xiao Lin Tang, Zhiwei He, Ming-Liang He, Paul BS Lai

J Transl Med. 2015; 13: 23. Published online 2015 Jan 27. doi: 10.1186/s12967-015-0382-7

PMCID:: PMC4311446

Abstract Article PDF–3.3M

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