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Select item 109696301.

UROMODULIN – A LINK BETWEEN SODIUM EXCRETION AND ALTERATION IN CIRCADIAN BLOOD PRESSURE PATTERN IN PREHYPERTENSIVES

Josipa Josipović, Livija Šimičević, Živka Dika, Nikola Bulj, Mislav Vrsalović, Bojan Jelaković

Acta Clin Croat. 2023 Aug; 62(2): 313–322. Published online 2023 Aug. doi: 10.20471/acc.2023.62.02.09

PMCID:: PMC10969630

Article PDF–376K

Select item 108246552.

The Versatile Role of Uromodulin in Renal Homeostasis and Its Relevance in Chronic Kidney Disease

Tomoaki Takata, Hajime Isomoto

Intern Med. 2024 Jan 1; 63(1): 17–23. Published online 2023 Jan 15. doi: 10.2169/internalmedicine.1342-22

PMCID:: PMC10824655

Article PDF–596K

Select item 105472243.

Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene

Azuma Nanamatsu, Radmila Micanovic, Shehnaz Khan, Tarek M. El-Achkar, Kaice A. LaFavers

Kidney360. 2023 Sep; 4(9): e1302–e1307. Published online 2023 Jun 21. doi: 10.34067/KID.0000000000000197

PMCID:: PMC10547224

Article PDF–758K

Select item 104033504.

Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men

Engi Abdel–Hady Algharably, Linda Elizabeth Villagomez Fuentes, Sarah Toepfer, Maximilian König, Vera Regitz-Zagrosek, Lars Bertram, Juliane Bolbrinker, Ilja Demuth, Reinhold Kreutz

J Hum Hypertens. 2023; 37(8): 709–717. Published online 2022 Nov 28. doi: 10.1038/s41371-022-00781-y

PMCID:: PMC10403350

Article PDF–865K

Select item 100864945.

A founder UMOD variant is a common cause of hereditary nephropathy in the British population

Manoj K Valluru, Noelle KX Chung, Mark Gilchrist, Laura Butland, Jackie Cook, Anna Takou, Abhijit Dixit, Michael N Weedon, Albert C M Ong, The Genomics England Research Consortium

J Med Genet. 2023 Apr; 60(4): 397–405. Published online 2022 Aug 29. doi: 10.1136/jmg-2022-108704

PMCID:: PMC10086494

Article PDF–3.8M

Select item 96494236.

Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults

Linda Elizabeth Villagomez Fuentes, Engi Abdel–Hady Algharably, Sarah Toepfer, Maximilian König, Ilja Demuth, Lars Bertram, Reinhold Kreutz, Juliane Bolbrinker

J Hum Hypertens. 2022; 36(11): 983–988. Published online 2021 Sep 30. doi: 10.1038/s41371-021-00608-2

PMCID:: PMC9649423

Article PDF–557K

Select item 93881137.

An intermediate-effect size variant in UMOD confers risk for chronic kidney disease

Eric Olinger, Céline Schaeffer, Kendrah Kidd, Elhussein A. E. Elhassan, Yurong Cheng, Inès Dufour, Guglielmo Schiano, Holly Mabillard, Elena Pasqualetto, Patrick Hofmann, Daniel G. Fuster, Andreas D. Kistler, Ian J. Wilson, Stanislav Kmoch, Laure Raymond, Thomas Robert, Genomics England Research Consortium, Kai-Uwe Eckardt, Anthony J. Bleyer, Sr., Anna Köttgen, Peter J. Conlon, Michael Wiesener, John A. Sayer, Luca Rampoldi, Olivier Devuyst

Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2114734119. Published online 2022 Aug 10. doi: 10.1073/pnas.2114734119

PMCID:: PMC9388113

Article PDF–1.8M

Select item 86206168.

UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study

Jinwei Wang, Lili Liu, Kevin He, Bixia Gao, Fang Wang, Minghui Zhao, Luxia Zhang, on behalf of the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

Genes (Basel) 2021 Nov; 12(11): 1687. Published online 2021 Oct 23. doi: 10.3390/genes12111687

PMCID:: PMC8620616

Article PDF–983K

Select item 77833959.

Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo

Roland Immler, Bärbel Lange-Sperandio, Tobias Steffen, Heike Beck, Ina Rohwedder, Jonas Roth, Matteo Napoli, Georg Hupel, Frederik Pfister, Bastian Popper, Bernd Uhl, Hanna Mannell, Christoph A. Reichel, Volker Vielhauer, Jürgen Scherberich, Markus Sperandio, Monika Pruenster

Front Immunol. 2020; 11: 588245. Published online 2020 Dec 22. doi: 10.3389/fimmu.2020.588245

PMCID:: PMC7783395

Article PDF–9.7M

Select item 773761910.

Cryo‐EM structure of native human uromodulin, a zona pellucida module polymer

Alena Stsiapanava, Chenrui Xu, Martina Brunati, Sara Zamora‐Caballero, Céline Schaeffer, Marcel Bokhove, Ling Han, Hans Hebert, Marta Carroni, Shigeki Yasumasu, Luca Rampoldi, Bin Wu, Luca Jovine

EMBO J. 2020 Dec 15; 39(24): e106807. Published online 2020 Nov 16. doi: 10.15252/embj.2020106807

PMCID:: PMC7737619

Article PDF–4.6M

Select item 761111011.

Mechanistic Interactions of Uromodulin with the Thick Ascending Limb: Perspectives in Physiology and Hypertension

Philipp Boder, Sheon Mary, Patrick B. Mark, James Leiper, Anna F. Dominiczak, Sandosh Padmanabhan, Luca Rampoldi, Christian Delles

J Hypertens. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: J Hypertens. 2021 Aug 1; 39(8): 1490–1504. doi: 10.1097/HJH.0000000000002861

PMCID:: PMC7611110

Article PDF–1.2M

Select item 748612412.

The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism

Jessica J Stanisich, Dawid S Zyla, Pavel Afanasyev, Jingwei Xu, Anne Kipp, Eric Olinger, Olivier Devuyst, Martin Pilhofer, Daniel Boehringer, Rudi Glockshuber

eLife. 2020; 9: e60265. Published online 2020 Aug 20. doi: 10.7554/eLife.60265

PMCID:: PMC7486124

Article PDF–2.5M

Select item 746272413.

Association of serum uromodulin with mortality and cardiovascular disease in the elderly—the Cardiovascular Health Study

Dominik Steubl, Petra Buzkova, Pranav S Garimella, Joachim H Ix, Prasad Devarajan, Michael R Bennett, Paulo H M Chaves, Michael G Shlipak, Nisha Bansal, Mark J Sarnak

Nephrol Dial Transplant. 2020 Aug; 35(8): 1399–1405. Published online 2019 Mar 21. doi: 10.1093/ndt/gfz008

PMCID:: PMC7462724

Article PDF–279K

Select item 744906714.

A novel likely pathogenic variant in the UMOD gene in a family with autosomal dominant tubulointerstitial kidney disease: a case report

Ying Wang, Haibo Liu, Qingnan He, Zhuwen Yi, Yongzhen Li, Xiqiang Dang

BMC Nephrol. 2020; 21: 368. Published online 2020 Aug 26. doi: 10.1186/s12882-020-02022-1

PMCID:: PMC7449067

Article PDF–1.0M

Select item 741354115.

Serum uromodulin is inversely associated with arterial hypertension and the vasoconstrictive prohormone CT-proET-1 in the population-based KORA F4 study

Cornelia Then, Barbara Thorand, Holger L. Then, Christa Meisinger, Margit Heier, Annette Peters, Wolfgang Koenig, Wolfgang Rathmann, Martin Bidlingmaier, Andreas Lechner, Martin Reincke, Jürgen E. Scherberich, Jochen Seissler

PLoS One. 2020; 15(8): e0237364. Published online 2020 Aug 7. doi: 10.1371/journal.pone.0237364

PMCID:: PMC7413541

Article PDF–455K

Select item 726921916.

Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD

Dominik Steubl, Markus P. Schneider, Heike Meiselbach, Jennifer Nadal, Matthias C. Schmid, Turgay Saritas, Vera Krane, Claudia Sommerer, Seema Baid-Agrawal, Jakob Voelkl, Fruzsina Kotsis, Anna Köttgen, Kai-Uwe Eckardt, Jürgen E. Scherberich, GCKD Study Investigators

Clin J Am Soc Nephrol. 2020 May 7; 15(5): 616–624. Published online 2020 Apr 14. doi: 10.2215/CJN.11780919

PMCID:: PMC7269219

Article

Select item 705010917.

Peptidomic Analysis of Urine from Youths with Early Type 1 Diabetes Reveals Novel Bioactivity of Uromodulin Peptides In Vitro

Julie A. D. Van, Sergi Clotet-Freixas, Joyce Zhou, Ihor Batruch, Chunxiang Sun, Michael Glogauer, Luca Rampoldi, Yesmino Elia, Farid H. Mahmud, Etienne Sochett, Eleftherios P. Diamandis, James W. Scholey, Ana Konvalinka

Mol Cell Proteomics. 2020 Mar; 19(3): 501–517. Published online 2019 Dec 26. doi: 10.1074/mcp.RA119.001858

PMCID:: PMC7050109

Article PDF–2.8M

Select item 684299218.

Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study

Kavish R. Patidar, Pranav S. Garimella, Etienne Macedo, James E. Slaven, Marwan S. Ghabril, Regina E. Weber, Melissa Anderson, Eric S. Orman, Lauren D. Nephew, Archita P. Desai, Naga P. Chalasani, Tarek M. El-Achkar

Am J Physiol Gastrointest Liver Physiol. 2019 Oct 1; 317(4): G447–G452. Published online 2019 Aug 14. doi: 10.1152/ajpgi.00158.2019

PMCID:: PMC6842992

Article

Select item 675462319.

Serum Uromodulin: A Biomarker of Long-Term Kidney Allograft Failure

Andrew Bostom, Dominik Steubl, Pranav S. Garimella, Nora Franceschini, Mary B. Roberts, Andreas Pasch, Joachim H. Ix, Katherine R. Tuttle, Anastasia Ivanova, Theresa Shireman, S. Joseph Kim, Reginald Gohh, Daniel E. Weiner, Andrew S. Levey, Chi-yuan Hsu, John W. Kusek, Charles B. Eaton

Am J Nephrol. Author manuscript; available in PMC 2019 Sep 21.

Published in final edited form as: Am J Nephrol. 2018; 47(4): 275–282. Published online 2018 Apr 26. doi: 10.1159/000489095

PMCID:: PMC6754623

Article PDF–85K

Select item 669074720.

Serum Uromodulin Is Associated with Urinary Albumin Excretion in Adolescents with Type 1 Diabetes

Pattara Wiromrat, Petter Bjornstad, Carlos Roncal, Laura Pyle, Richard J. Johnson, David Z. Cherney, Tyler Lipina, Franziska Bishop, David M. Maahs, R. Paul Wadwa

J Diabetes Complications. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: J Diabetes Complications. 2019 Sep; 33(9): 648–650. Published online 2019 Jun 3. doi: 10.1016/j.jdiacomp.2019.05.023

PMCID:: PMC6690747

Article PDF–299K

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