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Select item 109219691.

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

B Patel, Y Kang, K Cui, M Litt, MSJ Riberio, C Deng, T Salz, S Casada, X Fu, Y Qiu, K Zhao, S Huang

Leukemia. Author manuscript; available in PMC 2024 Mar 8.

Published in final edited form as: Leukemia. 2014 Feb; 28(2): 349–361. Published online 2013 May 23. doi: 10.1038/leu.2013.158

PMCID:: PMC10921969

Abstract Article PDF–2.3M

Select item 101535422.

TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3’ neo-enhancer

Charlotte Smith, Ashish Goyal, Dieter Weichenhan, Eric Allemand, Anand Mayakonda, Umut Toprak, Anna Riedel, Estelle Balducci, Manisha Manojkumar, Anastasija Pejkovska, Oliver Mücke, Etienne Sollier, Ali Bakr, Kersten Breuer, Pavlo Lutsik, Olivier Hermine, Salvatore Spicuglia, Vahid Asnafi, Christoph Plass, Aurore Touzart

Haematologica. 2023 May 1; 108(5): 1259–1271. Published online 2023 Jan 12. doi: 10.3324/haematol.2022.281583

PMCID:: PMC10153542

Abstract Article PDF–2.0M

Select item 76582023.

Dengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1

Atoshi Banerjee, Aarti Tripathi, Shweta Duggal, Arup Banerjee, Sudhanshu Vrati

Sci Rep. 2020; 10: 19587. Published online 2020 Nov 11. doi: 10.1038/s41598-020-76350-5

PMCID:: PMC7658202

Abstract Article PDF–1.4M

Select item 73433634.

MiR-7 Functions as a Tumor Suppressor by Targeting the Oncogenes TAL1 in T-Cell Acute Lymphoblastic Leukemia

Hongbo Sun, Zhifu Zhang, Wei Luo, Junmin Liu, Ye Lou, Shengmei Xia

Technol Cancer Res Treat. 2020; 19: 1533033820934130. Published online 2020 Jul 7. doi: 10.1177/1533033820934130

PMCID:: PMC7343363

Abstract Article PDF–1.0M

Select item 44268065.

SCL/TAL1-mediated Transcriptional Network Enhances Megakaryocytic Specification of Human Embryonic Stem Cells

Miguel G Toscano, Oscar Navarro-Montero, Veronica Ayllon, Veronica Ramos-Mejia, Xiomara Guerrero-Carreno, Clara Bueno, Tamara Romero, Mar Lamolda, Marien Cobo, Francisco Martin, Pablo Menendez, Pedro J Real

Mol Ther. 2015 Jan; 23(1): 158–170. Prepublished online 2014 Oct 8. Published online 2014 Nov 4. doi: 10.1038/mt.2014.196

PMCID:: PMC4426806

Abstract Article PDF–2.5M

Select item 34225046.

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T-cell Acute Lymphoblastic Leukemia

Takaomi Sanda, Lee N. Lawton, M. Inmaculada Barrasa, Zi Peng Fan, Holger Kohlhammer, Alejandro Gutierrez, Wenxue Ma, Jessica Tatarek, Yebin Ahn, Michelle A. Kelliher, Catriona H. M. Jamieson, Louis M. Staudt, Richard A. Young, A. Thomas Look

Cancer Cell. Author manuscript; available in PMC 2013 Aug 14.

Published in final edited form as: Cancer Cell. 2012 Aug 14; 22(2): 209–221. doi: 10.1016/j.ccr.2012.06.007

PMCID:: PMC3422504

Abstract Article PDF–3.8M

Select item 28167017.

Genomic Approaches Uncover Increasing Complexities in the Regulatory Landscape at the Human SCL (TAL1) Locus

Pawandeep Dhami, Alexander W. Bruce, Johanna H. Jim, Shane C. Dillon, Amanda Hall, Jonathan L. Cooper, Nicolas Bonhoure, Kelly Chiang, Peter D. Ellis, Cordelia Langford, Robert M. Andrews, David Vetrie

PLoS One. 2010; 5(2): e9059. Published online 2010 Feb 5. doi: 10.1371/journal.pone.0009059

PMCID:: PMC2816701

Abstract Article PDF–1.8M

Select item 21886668.

Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia

J Exp Med. 1990 Nov 1; 172(5): 1403–1408. doi: 10.1084/jem.172.5.1403

PMCID:: PMC2188666

Summary PDF–556K

Select item 18958599.

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Teresa Palomero, Duncan T. Odom, Jennifer O'Neil, Adolfo A. Ferrando, Adam Margolin, Donna S. Neuberg, Stuart S. Winter, Richard S. Larson, Wei Li, X. Shirley Liu, Richard A. Young, A. Thomas Look

Blood. 2006 Aug 1; 108(3): 986–992. Prepublished online 2006 Apr 18. doi: 10.1182/blood-2005-08-3482

PMCID:: PMC1895859

Abstract Article

Select item 819765910.

Identification of novel lncRNAs regulated by the TAL1 complex in T-cell acute lymphoblastic leukemia

Phuong Cao Thi Ngoc, Shi Hao Tan, Tze King Tan, Min Min Chan, Zhenhua Li, Allen. E. J. Yeoh, Daniel G Tenen, Takaomi Sanda

Leukemia. Author manuscript; available in PMC 2021 Jun 12.

Published in final edited form as: Leukemia. 2018 Oct; 32(10): 2138–2151. Published online 2018 Mar 26. doi: 10.1038/s41375-018-0110-4

PMCID:: PMC8197659

Abstract Article PDF–4.0M

Select item 772289711.

The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis

Annekarin Meyer, Stefanie Herkt, Heike Kunze-Schumacher, Nicole Kohrs, Julia Ringleb, Lucas Schneider, Olga N. Kuvardina, Thomas Oellerich, Björn Häupl, Andreas Krueger, Erhard Seifried, Halvard Bonig, Joern Lausen

Sci Rep. 2020; 10: 21438. Published online 2020 Dec 8. doi: 10.1038/s41598-020-78629-z

PMCID:: PMC7722897

Abstract Article PDF–6.3M

Select item 710294612.

Alteration of CTCF-associated chromatin neighborhood inhibits TAL1-driven oncogenic transcription program and leukemogenesis

Ying Li, Ziwei Liao, Huacheng Luo, Aissa Benyoucef, Yuanyuan Kang, Qian Lai, Sinisa Dovat, Barbara Miller, Iouri Chepelev, Yangqiu Li, Keji Zhao, Marjorie Brand, Suming Huang

Nucleic Acids Res. 2020 Apr 6; 48(6): 3119–3133. Published online 2020 Feb 22. doi: 10.1093/nar/gkaa098

PMCID:: PMC7102946

Abstract Article PDF–2.2M

Select item 633633613.

FUSE binding protein 1 (FUBP1) expression is upregulated by T-cell acute lymphocytic leukemia protein 1 (TAL1) and required for efficient erythroid differentiation

Marlene Steiner, Lucas Schneider, Jasmin Yillah, Katharina Gerlach, Olga N. Kuvardina, Annekarin Meyer, Alisa Maring, Halvard Bonig, Erhard Seifried, Martin Zörnig, Jörn Lausen

PLoS One. 2019; 14(1): e0210515. Published online 2019 Jan 17. doi: 10.1371/journal.pone.0210515

PMCID:: PMC6336336

Abstract Article PDF–3.1M

Select item 628658714.

MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1

Mengge Wang, Hongtao Wang, Yuqi Wen, Xiaoyuan Chen, Xin Liu, Jie Gao, Pei Su, Yuanfu Xu, Wen Zhou, Lihong Shi, Jiaxi Zhou

Stem Cell Res Ther. 2018; 9: 340. Published online 2018 Dec 7. doi: 10.1186/s13287-018-1074-z

Correction in:: Stem Cell Res Ther. 2020; 11: 446.

PMCID:: PMC6286587

Abstract Article PDF–3.3M

Select item 557651015.

Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis

Nathan J. Palpant, Yuliang Wang, Brandon Hadland, Rebecca J. Zaunbrecher, Meredith Redd, Daniel Jones, Lil Pabon, Rajan Jain, Jonathan Epstein, Walter L. Ruzzo, Ying Zheng, Irwin Bernstein, Adam Margolin, Charles E. Murry

Cell Rep. Author manuscript; available in PMC 2017 Aug 30.

Published in final edited form as: Cell Rep. 2017 Aug 15; 20(7): 1597–1608. doi: 10.1016/j.celrep.2017.07.067

PMCID:: PMC5576510

Abstract Article PDF–2.3M

Select item 543663816.

Splicing factor SF3B1^K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

Shuiling Jin, Hairui Su, Ngoc-Tung Tran, Jing Song, Sydney S. Lu, Ying Li, Suming Huang, Omar Abdel-Wahab, Yanyan Liu, Xinyang Zhao

PLoS One. 2017; 12(5): e0175523. Published online 2017 May 18. doi: 10.1371/journal.pone.0175523

PMCID:: PMC5436638

Abstract Article PDF–5.3M

Select item 472052117.

An Oncogenic Super-Enhancer Formed Through Somatic Mutation of a Noncoding Intergenic Element

Marc R. Mansour, Brian J Abraham, Lars Anders, Alla Berezovskaya, Alejandro Gutierrez, Adam D Durbin, Julia Etchin, Lee Lawton, Stephen E. Sallan, Lewis B. Silverman, Mignon L. Loh, Stephen P. Hunger, Takaomi Sanda, Richard A. Young, A. Thomas Look

Science. Author manuscript; available in PMC 2016 Jan 20.

Published in final edited form as: Science. 2014 Dec 12; 346(6215): 1373–1377. Published online 2014 Nov 13. doi: 10.1126/science.1259037

PMCID:: PMC4720521

Abstract Article PDF–926K

Select item 436931318.

Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence

Tõnis Org, Dan Duan, Roberto Ferrari, Amelie Montel-Hagen, Ben Van Handel, Marc A Kerényi, Rajkumar Sasidharan, Liudmilla Rubbi, Yuko Fujiwara, Matteo Pellegrini, Stuart H Orkin, Siavash K Kurdistani, Hanna KA Mikkola

EMBO J. 2015 Mar 12; 34(6): 759–777. Published online 2015 Jan 7. doi: 10.15252/embj.201490542

PMCID:: PMC4369313

Abstract Article PDF–3.5M

Select item 390321919.

Analysis of chromatin-state plasticity identifies cell-type–specific regulators of H3K27me3 patterns

Luca Pinello, Jian Xu, Stuart H. Orkin, Guo-Cheng Yuan

Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3): E344–E353. Published online 2014 Jan 6. doi: 10.1073/pnas.1322570111

PMCID:: PMC3903219

Abstract Article PDF–1.9M

Select item 376760920.

SIL-TAL1 Rearrangement is Related with Poor Outcome: A Study from a Chinese Institution

Di Wang, Guangrong Zhu, Na Wang, Xiaoxi Zhou, Yunfan Yang, Shiqiu Zhou, Jie Xiong, Jing He, Lijun Jiang, Chunrui Li, Danmei Xu, Liang Huang, Jianfeng Zhou

PLoS One. 2013; 8(9): e73865. Published online 2013 Sep 9. doi: 10.1371/journal.pone.0073865

PMCID:: PMC3767609

Abstract Article PDF–377K

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PMC Links for Gene (Select 6886) (73)
PMC
fibroblast growth factor 17 isoform 2 precursor [Mus musculus]
fibroblast growth factor 17 isoform 2 precursor [Mus musculus]
gi|1335348705|ref|NP_001347037.1|

Protein
uncharacterized protein LOC226691 isoform X4 [Mus musculus]
uncharacterized protein LOC226691 isoform X4 [Mus musculus]
gi|1907068450|ref|XP_036020035.1|

Protein
Mus musculus
Mus musculus
RefSeq annotation of the mouse reference genome assembly.

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BioProject Links for Protein (Select 1104876374) (1)
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