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Select item 95937301.

KLF15 controls brown adipose tissue transcriptional flexibility and metabolism in response to various energetic demands

Liyan Fan, Alexander F. Lesser, David R. Sweet, Komal S. Keerthy, Yuan Lu, Ernest R. Chan, Vinesh Vinayachandran, Olga Ilkayeva, Tapatee Das, Christopher B. Newgard, Mukesh K. Jain

iScience. 2022 Nov 18; 25(11): 105292. Published online 2022 Oct 8. doi: 10.1016/j.isci.2022.105292

PMCID:: PMC9593730

Article PDF–2.3M

Select item 87504382.

KLF15 overexpression in myocytes fails to ameliorate ALS-related pathology or extend the lifespan of SOD1G93A mice

Ryan Massopust, Devin Juros, Dillon Shapiro, Mikayla Lopes, Saptarsi M. Haldar, Thomas Taetzsch, Gregorio Valdez

Neurobiol Dis. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Neurobiol Dis. 2022 Jan; 162: 105583. Published online 2021 Dec 11. doi: 10.1016/j.nbd.2021.105583

PMCID:: PMC8750438

Article PDF–2.8M

Select item 78803113.

Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis

Liyan Fan, David R. Sweet, Domenick A. Prosdocimo, Vinesh Vinayachandran, Ernest R. Chan, Rongli Zhang, Olga Ilkayeva, Yuan Lu, Komal S. Keerthy, Chloe E. Booth, Christopher B. Newgard, Mukesh K. Jain

J Clin Invest. 2021 Feb 15; 131(4): e139496. Published online 2021 Feb 15. doi: 10.1172/JCI139496

PMCID:: PMC7880311

Article PDF–4.5M

Select item 71974414.

KLF15 Regulates the Circadian Susceptibility to Ischemia Reperfusion Injury in the Heart

Le Li, Hui Li, Chih-Liang Tien, Mukesh K. Jain, Lilei Zhang

Circulation. Author manuscript; available in PMC 2021 Apr 28.

Published in final edited form as: Circulation. 2020 Apr 28; 141(17): 1427–1429. Published online 2020 Apr 27. doi: 10.1161/CIRCULATIONAHA.119.041664

PMCID:: PMC7197441

Article PDF–417K

Select item 71699545.

Transcriptome analysis of Klf15-mediated inhibitory functions in a mouse deep venous thrombosis model

Jin Zhou, Xueling Zhao, Shiwei Xie, Rudan Zhou

Int J Mol Med. 2020 Jun; 45(6): 1735–1752. Published online 2020 Mar 13. doi: 10.3892/ijmm.2020.4538

PMCID:: PMC7169954

Article PDF–1.3M

Select item 67608336.

A mutation in mouse Krüppel-like factor 15 alters the gut microbiome and response to obesogenic diet

Karen L. Svenson, Lauren L. Long, Steven L. Ciciotte, Mark D. Adams

PLoS One. 2019; 14(9): e0222536. Published online 2019 Sep 25. doi: 10.1371/journal.pone.0222536

PMCID:: PMC6760833

Article PDF–6.1M

Select item 61712757.

Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease

Yiqing Guo, Jesse Pace, Zhengzhe Li, Avi Ma’ayan, Zichen Wang, Monica P. Revelo, Edward Chen, Xiangchen Gu, Ahmed Attalah, Yaqi Yang, Chelsea Estrada, Vincent W. Yang, John C. He, Sandeep K. Mallipattu

J Am Soc Nephrol. 2018 Oct; 29(10): 2529–2545. Published online 2018 Aug 24. doi: 10.1681/ASN.2018030324

PMCID:: PMC6171275

Article

Select item 58006038.

Kruppel-like factor 15 is required for the cardiac adaptive response to fasting

Keiki Sugi, Paishiun N. Hsieh, Olga Ilkayeva, Shamanthika Shelkay, Bridget Moroney, Palvir Baadh, Browning Haynes, Megan Pophal, Liyan Fan, Christopher B. Newgard, Domenick A. Prosdocimo, Mukesh K. Jain

PLoS One. 2018; 13(2): e0192376. Published online 2018 Feb 6. doi: 10.1371/journal.pone.0192376

PMCID:: PMC5800603

Article PDF–4.3M

Select item 56512049.

The loss of Krüppel-like factor 15 in Foxd1⁺ stromal cells exacerbates kidney fibrosis

Xiangchen Gu, Sandeep K. Mallipattu, Yiqing Guo, Monica P. Revelo, Jesse Pace, Timothy Miller, Xiang Gao, Mukesh K. Jain, Agnieszka B. Bialkowska, Vincent W. Yang, John C. He, Changlin Mei

Kidney Int. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Kidney Int. 2017 Nov; 92(5): 1178–1193. Published online 2017 Jun 24. doi: 10.1016/j.kint.2017.03.037

PMCID:: PMC5651204

Article PDF–3.0M

Select item 482786010.

Megamitochondria in cardiomyocytes of a knockout (Klf15−/−) mouse

Bernard Tandler, Hisashi Fujioka, Charles L. Hoppel, Saptarsi M. Haldar, Mukesh K. Jain

Ultrastruct Pathol. Author manuscript; available in PMC 2016 Apr 11.

Published in final edited form as: Ultrastruct Pathol. 2015; 39(5): 336–339. Published online 2015 Jun 25. doi: 10.3109/01913123.2015.1042610

PMCID:: PMC4827860

Article PDF–498K

Select item 381197811.

Therapeutic Use of a Selective S1P₁ Receptor Modulator Ponesimod in Autoimmune Diabetes

Sylvaine You, Luca Piali, Chantal Kuhn, Beat Steiner, Virginia Sauvaget, Fabrice Valette, Martine Clozel, Jean-François Bach, Lucienne Chatenoud

PLoS One. 2013; 8(10): e77296. Published online 2013 Oct 24. doi: 10.1371/journal.pone.0077296

PMCID:: PMC3811978

Article PDF–1.1M

Select item 293718512.

KLF15 regulates smooth muscle response to vascular injury

Yuan Lu, Saptarsi Haldar, Kevin Croce, Yunmei Wang, Mashashi Sakuma, Toshifumi Morooka, Baiqiu Wang, Darwin Jeyaraj, Susan J Gray, Daniel I. Simon, Mukesh K. Jain

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8): 1550–1552. Published online 2010 May 27. doi: 10.1161/ATVBAHA.110.207050

PMCID:: PMC2937185

Article PDF–1.4M

Select item 189253013.

Regulation of Gluconeogenesis by Krüppel-like Factor 15

Susan Gray, Baiqiu Wang, Yvette Orihuela, Eun-Gyoung Hong, Sudeshna Fisch, Saptarsi Haldar, Gary W. Cline, Jason K. Kim, Odile D. Peroni, Barbara B. Kahn, Mukesh K. Jain

Cell Metab. Author manuscript; available in PMC 2007 Jun 15.

Published in final edited form as: Cell Metab. 2007 Apr; 5(4): 305–312. doi: 10.1016/j.cmet.2007.03.002

PMCID:: PMC1892530

Article PDF–399K

Select item 1062284214.

The transcriptional regulator KLF15 is necessary for myoblast differentiation and muscle regeneration by activating FKBP5

Shijuan Gao, Shan Huang, Yanhong Zhang, Guangming Fang, Yan Liu, Congcong Zhang, Yulin Li, Jie Du

J Biol Chem. 2023 Oct; 299(10): 105226. Published online 2023 Sep 4. doi: 10.1016/j.jbc.2023.105226

PMCID:: PMC10622842

Article PDF–5.7M

Select item 1057246815.

Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury

Xue Yang, Shihui Dong, Yun Fan, Yuanyuan Xia, Fan Yang, Zhaohong Chen, Dacheng Chen, Mingchao Zhang, Dandan Liang, Caihong Zeng

Int J Mol Sci. 2023 Oct; 24(19): 14530. Published online 2023 Sep 26. doi: 10.3390/ijms241914530

PMCID:: PMC10572468

Article PDF–8.0M

Select item 1003370316.

A defect in mitochondrial protein translation influences mitonuclear communication in the heart

Feng Gao, Tian Liang, Yao Wei Lu, Xuyang Fu, Xiaoxuan Dong, Linbin Pu, Tingting Hong, Yuxia Zhou, Yu Zhang, Ning Liu, Feng Zhang, Jianming Liu, Andrea P. Malizia, Hong Yu, Wei Zhu, Douglas B. Cowan, Hong Chen, Xinyang Hu, John D. Mably, Jian’an Wang, Da-Zhi Wang, Jinghai Chen

Nat Commun. 2023; 14: 1595. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37291-5

PMCID:: PMC10033703

Article PDF–10M

Select item 919000417.

Transcription factors KLF15 and PPARδ cooperatively orchestrate genome-wide regulation of lipid metabolism in skeletal muscle

Liyan Fan, David R. Sweet, Erica K. Fan, Domenick A. Prosdocimo, Annmarie Madera, Zhen Jiang, Roshan Padmanabhan, Saptarsi M. Haldar, Vinesh Vinayachandran, Mukesh K. Jain

J Biol Chem. 2022 Jun; 298(6): 101926. Published online 2022 Apr 9. doi: 10.1016/j.jbc.2022.101926