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Select item 54626231.

Canine Brachycephaly Is Associated with a Retrotransposon-Mediated Missplicing of SMOC2

Thomas W. Marchant, Edward J. Johnson, Lynn McTeir, Craig I. Johnson, Adam Gow, Tiziana Liuti, Dana Kuehn, Karen Svenson, Mairead L. Bermingham, Michaela Drögemüller, Marc Nussbaumer, Megan G. Davey, David J. Argyle, Roger M. Powell, Sérgio Guilherme, Johann Lang, Gert Ter Haar, Tosso Leeb, Tobias Schwarz, Richard J. Mellanby, Dylan N. Clements, Jeffrey J. Schoenebeck

Curr Biol. 2017 Jun 5; 27(11): 1573–1584.e6. doi: 10.1016/j.cub.2017.04.057

PMCID:: PMC5462623

Article

Select item 74812572.

Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss

Supawich Morkmued, François Clauss, Brigitte Schuhbaur, Valérie Fraulob, Eric Mathieu, Joseph Hemmerlé, Hans Clevers, Bon-Kyoung Koo, Pascal Dollé, Agnès Bloch-Zupan, Karen Niederreither

Sci Rep. 2020; 10: 14817. Published online 2020 Sep 9. doi: 10.1038/s41598-020-71749-6

PMCID:: PMC7481257

Article PDF–3.8M

Select item 59992373.

SMOC2 inhibits calcification of osteoprogenitor and endothelial cells

Tine Peeters, Silvia Monteagudo, Przemko Tylzanowski, Frank P. Luyten, Rik Lories, Frédéric Cailotto

PLoS One. 2018; 13(6): e0198104. Published online 2018 Jun 13. doi: 10.1371/journal.pone.0198104

PMCID:: PMC5999237

Article PDF–6.8M

Select item 53965224.

Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation

Casimiro Gerarduzzi, Ramya K. Kumar, Priyanka Trivedi, Amrendra K. Ajay, Ashwin Iyer, Sarah Boswell, John N. Hutchinson, Sushrut S. Waikar, Vishal S. Vaidya

JCI Insight. 2017 Apr 20; 2(8): e90299. Published online 2017 Apr 20. doi: 10.1172/jci.insight.90299

PMCID:: PMC5396522

Article PDF–2.7M

Select item 34000175.

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

Javier Muñoz, Daniel E Stange, Arnout G Schepers, Marc van de Wetering, Bon-Kyoung Koo, Shalev Itzkovitz, Richard Volckmann, Kevin S Kung, Jan Koster, Sorina Radulescu, Kevin Myant, Rogier Versteeg, Owen J Sansom, Johan H van Es, Nick Barker, Alexander van Oudenaarden, Shabaz Mohammed, Albert J R Heck, Hans Clevers

EMBO J. 2012 Jul 18; 31(14): 3079–3091. Published online 2012 Jun 12. doi: 10.1038/emboj.2012.166

PMCID:: PMC3400017

Article PDF–2.5M

Select item 26526666.

The Developmentally-Regulated Smoc2 Gene Is Repressed by Aryl-hydrocarbon Receptor (Ahr) Signaling

Peijun Liu, Dorothy E. Pazin, Rebeka R. Merson, Kenneth H. Albrecht, Cyrus Vaziri

Gene. Author manuscript; available in PMC 2010 Mar 15.

Published in final edited form as: Gene. 2009 Mar 15; 433(1-2): 72–80. Published online 2008 Dec 24. doi: 10.1016/j.gene.2008.12.010

PMCID:: PMC2652666

Article PDF–768K

Select item 85241537.

Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease

Cuiyan Xin, Jiahui Lei, Qian Wang, Yixia Yin, Xiaoqian Yang, Jose Alberto Moran Guerrero, Venkata Sabbisetti, Xiaoming Sun, Vishal S. Vaidya, Joseph V. Bonventre

iScience. 2021 Oct 22; 24(10): 103193. Published online 2021 Sep 29. doi: 10.1016/j.isci.2021.103193

PMCID:: PMC8524153

Article PDF–7.5M

Select item 21741898.

Peijun Liu, Jining Lu, Wellington V. Cardoso, Cyrus Vaziri

Mol Biol Cell. 2008 Jan; 19(1): 248–261. doi: 10.1091/mbc.E07-05-0510

PMCID:: PMC2174189

Article PDF–1.0M

Select item 12235519.

Characterization of SMOC-2, a modular extracellular calcium-binding protein.

Christian Vannahme, Silke Gösling, Mats Paulsson, Patrik Maurer, Ursula Hartmann

Biochem J. 2003 Aug 1; 373(Pt 3): 805–814. doi: 10.1042/BJ20030532

PMCID:: PMC1223551

Summary PDF–511K

Select item 1098079310.

Segregation of morphogenetic regulatory function of Shox2 from its cell fate guardian role in sinoatrial node development

Hua Li, Qinghuang Tang, Tianfang Yang, Zhengsen Wang, Dainan Li, Linyan Wang, Liwen Li, Yaoyi Chen, Hai Huang, Yanding Zhang, YiPing Chen

Commun Biol. 2024; 7: 385. Published online 2024 Mar 29. doi: 10.1038/s42003-024-06039-2

PMCID:: PMC10980793

Article PDF–7.7M

Select item 667565511.

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution

William R. Goodyer, Benjamin M. Beyersdorf, David T. Paik, Lei Tian, Guang Li, Jan W. Buikema, Orlando Chirikian, Shannon Choi, Sneha Venkatraman, Eliza L. Adams, Marc Tessier-Lavigne, Joseph C. Wu, Sean M. Wu

Circ Res. Author manuscript; available in PMC 2020 Aug 2.

Published in final edited form as: Circ Res. 2019 Aug 2; 125(4): 379–397. Published online 2019 Jul 9. doi: 10.1161/CIRCRESAHA.118.314578

PMCID:: PMC6675655

Article PDF–5.1M

Select item 323437212.

Homozygosity Mapping and Candidate Prioritization Identify Mutations, Missed by Whole-Exome Sequencing, in SMOC2, Causing Major Dental Developmental Defects

Agnès Bloch-Zupan, Xavier Jamet, Christelle Etard, Virginie Laugel, Jean Muller, Véronique Geoffroy, Jean-Pierre Strauss, Valérie Pelletier, Vincent Marion, Olivier Poch, Uwe Strahle, Corinne Stoetzel, Hélène Dollfus

Am J Hum Genet. 2011 Dec 9; 89(6): 773–781. doi: 10.1016/j.ajhg.2011.11.002

PMCID:: PMC3234372

Article PDF–732K

Select item 852661813.

Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2

Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Sachi Kobayashi, Kanta Wakamori, Chika Fujiwara, Eriko Nakamura, Kayon Yu, Hiroshi Kiyonari, Kana Bando, Tomohiko Murakami, Toshihisa Komori, Kenji Hata, Riko Nishimura

Commun Biol. 2021; 4: 1199. Published online 2021 Oct 19. doi: 10.1038/s42003-021-02717-7

PMCID:: PMC8526618

Article PDF–6.6M

Select item 667937014.

Nkx2-5 defines a subpopulation of pacemaker cells and is essential for the physiological function of the sinoatrial node in mice

Hua Li, Dainan Li, Yuzhi Wang, Zhen Huang, Jue Xu, Tianfang Yang, Linyan Wang, Qinghuang Tang, Chen-Leng Cai, Hai Huang, Yanding Zhang, YiPing Chen

Development. 2019 Jul 15; 146(14): dev178145. Published online 2019 Jul 25. doi: 10.1242/dev.178145

PMCID:: PMC6679370

Article

Select item 307046415.

Developmental Expression of Smoc1 and Smoc2 Suggests Potential Roles in Fetal Gonad and Reproductive Tract Differentiation

Dorothy E. Pazin, Kenneth H. Albrecht

Dev Dyn. Author manuscript; available in PMC 2011 Apr 4.

Published in final edited form as: Dev Dyn. 2009 Nov; 238(11): 2877–2890. doi: 10.1002/dvdy.22124

PMCID:: PMC3070464

Article PDF–2.8M

Select item 359759416.

The Etiology of Cleft Palate Formation in BMP7-Deficient Mice

Thaleia Kouskoura, Anastasiia Kozlova, Maria Alexiou, Susanne Blumer, Vasiliki Zouvelou, Christos Katsaros, Matthias Chiquet, Thimios A. Mitsiadis, Daniel Graf

PLoS One. 2013; 8(3): e59463. Published online 2013 Mar 14. doi: 10.1371/journal.pone.0059463

PMCID:: PMC3597594

Article PDF–23M

Select item 956689917.

In vivo visualization and molecular targeting of the cardiac conduction system

William R. Goodyer, Benjamin M. Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, Darren Salmi, Elise R. Robinson, Stephan Rogalla, Dillon P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu

J Clin Invest. 2022 Oct 17; 132(20): e156955. Published online 2022 Oct 17. doi: 10.1172/JCI156955

PMCID:: PMC9566899

Article PDF–9.4M

Select item 544174018.

Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development

Meade Haller, Qianxing Mo, Akira Imamoto, Dolores J. Lamb

Proc Natl Acad Sci U S A. 2017 May 9; 114(19): 4981–4986. Published online 2017 Apr 24. doi: 10.1073/pnas.1619523114

PMCID:: PMC5441740

Article PDF–3.0M

Select item 977136519.

TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development

Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai

eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405