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Select item 109429841.

RAD51 restricts DNA over-replication from re-activated origins

Sergio Muñoz, Elena Blanco-Romero, Daniel González-Acosta, Sara Rodriguez-Acebes, Diego Megías, Massimo Lopes, Juan Méndez

EMBO J. 2024 Mar; 43(6): 1043–1064. Published online 2024 Feb 15. doi: 10.1038/s44318-024-00038-z

PMCID:: PMC10942984

Article PDF–5.7M

Select item 107346672.

Differential impact of cytoplasmic vs. nuclear RAD51 expression on breast cancer progression and patient prognosis

Yen-Yun Wang, Kuang-Hung Cheng, Amos C. Hung, Steven Lo, Pang-Yu Chen, Yi-Chia Wu, Ming-Feng Hou, Shyng-Shiou F. Yuan

Int J Oncol. 2024 Feb; 64(2): 12. Published online 2023 Dec 7. doi: 10.3892/ijo.2023.5600

PMCID:: PMC10734667

Article PDF–6.6M

Select item 107344633.

SARS-CoV-2 exploits cellular RAD51 to promote viral propagation: implication of RAD51 inhibitor as a potential drug candidate against COVID-19

Thuy X. Pham, Trang T. X. Huynh, Jiwon Choi, Jae-Bong Lee, Seok-Chan Park, Bumseok Kim, Yun-Sook Lim, Soon B. Hwang

J Virol. 2023 Dec; 97(12): e01737-23. Published online 2023 Dec 5. doi: 10.1128/jvi.01737-23

PMCID:: PMC10734463

Article PDF–7.7M

Select item 107165814.

Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities

Sijia Liu, Akira Shinohara, Asako Furukohri

J Biol Chem. 2023 Dec; 299(12): 105424. Published online 2023 Nov 2. doi: 10.1016/j.jbc.2023.105424

PMCID:: PMC10716581

Article PDF–2.7M

Select item 101787575.

RAD51 Inhibition Shows Antitumor Activity in Hepatocellular Carcinoma

Mingang Pan, Yu Sha, Jianguo Qiu, Yunmeng Chen, Lele Liu, Muyu Luo, Ailong Huang, Jie Xia

Int J Mol Sci. 2023 May; 24(9): 7905. Published online 2023 Apr 26. doi: 10.3390/ijms24097905

PMCID:: PMC10178757

Article PDF–3.7M

Select item 95702516.

Human RAD51 Protein Forms Amyloid-like Aggregates In Vitro

Daniel V. Kachkin, Kirill V. Volkov, Julia V. Sopova, Alexander G. Bobylev, Sergei A. Fedotov, Sergei G. Inge-Vechtomov, Oxana V. Galzitskaya, Yury O. Chernoff, Aleksandr A. Rubel, Anna Y. Aksenova

Int J Mol Sci. 2022 Oct; 23(19): 11657. Published online 2022 Oct 1. doi: 10.3390/ijms231911657

PMCID:: PMC9570251

Article PDF–1.4M

Select item 93776197.

RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress

Sonia Feu, Fernando Unzueta, Amaia Ercilla, Alejandro Pérez-Venteo, Montserrat Jaumot, Neus Agell

PLoS One. 2022; 17(8): e0266645. Published online 2022 Aug 15. doi: 10.1371/journal.pone.0266645

PMCID:: PMC9377619

Article PDF–2.2M

Select item 93095398.

CRISPR/Cas9-induced saturated mutagenesis identifies Rad51 haplotype as a marker of PARP inhibitor sensitivity in breast cancer

Hua Yang, Yaning Wei, Qian Zhang, Yang Yang, Xuebing Bi, Lin Yang, Na Xiao, Aimin Zang, Lili Ren, Xiaoli Li

Mol Med Rep. 2022 Aug; 26(2): 258. Published online 2022 Jun 16. doi: 10.3892/mmr.2022.12774

PMCID:: PMC9309539

Article PDF–1.8M

Select item 89953909.

High RAD51 gene expression is associated with aggressive biology and with poor survival in breast cancer

Rongrong Wu, Ankit Patel, Yoshihisa Tokumaru, Mariko Asaoka, Masanori Oshi, Li Yan, Takashi Ishikawa, Kazuaki Takabe

Breast Cancer Res Treat. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Breast Cancer Res Treat. 2022 May; 193(1): 49–63. Published online 2022 Mar 6. doi: 10.1007/s10549-022-06552-0

PMCID:: PMC8995390

Article PDF–2.2M

Select item 883717210.

Cytoprotective Activity of Polyamines Is Associated with the Alternative Splicing of RAD51A Pre-mRNA in Normal Human CD4⁺ T Lymphocytes

Yulia A. Gladilina, Lylia Bey, Abdullah Hilal, Ekaterina V. Neborak, Varvara G. Blinova, Dmitry D. Zhdanov

Int J Mol Sci. 2022 Feb; 23(3): 1863. Published online 2022 Feb 7. doi: 10.3390/ijms23031863

PMCID:: PMC8837172

Article PDF–4.6M

Select item 880654411.

Identification of Rad51 as a prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma

Hao Xu, Chen Xiong, Yuan Chen, Chi Zhang, Dousheng Bai

Bioengineered. 2021; 12(1): 2664–2675. Published online 2021 Jun 11. doi: 10.1080/21655979.2021.1938470

PMCID:: PMC8806544

Article PDF–2.3M

Select item 872702412.

Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats

Laurens H. Lindenburg, Teodors Pantelejevs, Fabrice Gielen, Pedro Zuazua-Villar, Maren Butz, Eric Rees, Clemens F. Kaminski, Jessica A. Downs, Marko Hyvönen, Florian Hollfelder

Proc Natl Acad Sci U S A. 2021 Nov 16; 118(46): e2017708118. Published online 2021 Nov 11. doi: 10.1073/pnas.2017708118

PMCID:: PMC8727024

Article PDF–1.9M

Select item 859567013.

Primary Vestibular Schwannoma Cells Activate p21 and RAD51-Associated DNA Repair Following Radiation-Induced DNA Damage

Torin P. Thielhelm, Stefania Goncalves, Scott Welford, Eric A. Mellon, Olena Bracho, Michael Estivil, Clifford Brown, Jacques Morcos, Michael E. Ivan, Fred Telischi, Cristina Fernandez-Valle, Christine T. Dinh

Otol Neurotol. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Otol Neurotol. 2021 Dec 1; 42(10): e1600–e1608. doi: 10.1097/MAO.0000000000003322

PMCID:: PMC8595670

Article PDF–1.2M

Select item 859303514.

Nucleolar and spindle associated protein 1 enhances chemoresistance through DNA damage repair pathway in chronic lymphocytic leukemia by binding with RAD51

Yang Han, Xinting Hu, Xiaoya Yun, Jiarui Liu, Juan Yang, Zheng Tian, Xin Zhang, Ya Zhang, Xin Wang

Cell Death Dis. 2021 Nov; 12(11): 1083. Published online 2021 Nov 15. doi: 10.1038/s41419-021-04368-2

PMCID:: PMC8593035

Article PDF–4.1M

Select item 843338015.

The RAD51 recombinase protects mitotic chromatin in human cells

Isabel E. Wassing, Emily Graham, Xanita Saayman, Lucia Rampazzo, Christine Ralf, Andrew Bassett, Fumiko Esashi

Nat Commun. 2021; 12: 5380. Published online 2021 Sep 10. doi: 10.1038/s41467-021-25643-y

PMCID:: PMC8433380

Article PDF–2.4M

Select item 838479516.

The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization

Fábio Santiago, Rafaele Tavares Silvestre, Ubirani Barros Otero, Marianne Medeiros Tabalipa, Marilza de Moura Ribeiro-Carvalho, Luciano Rios Scherrer, Ahmed Al-Rikabi, Thomas Liehr, Gilda Alves, Maria Helena Ornellas

Int Arch Occup Environ Health. 2021; 94(7): 1567–1577. Published online 2021 Mar 28. doi: 10.1007/s00420-021-01652-8