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Select item 103312941.

Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis

Breanne N. Steffan, Dante Calise, Sung Chul Park, Mengyao Niu, Jun Yang, Bruce D. Hammock, MaryJane Jones, Chad Steele, Nancy P. Keller

Front Immunol. 2023; 14: 1173544. Published online 2023 Jun 26. doi: 10.3389/fimmu.2023.1173544

PMCID:: PMC10331294

Article PDF–5.1M

Select item 74091602.

The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain

Tabea Osthues, Béla Zimmer, Vittoria Rimola, Kevin Klann, Karin Schilling, Praveen Mathoor, Carlo Angioni, Andreas Weigert, Gerd Geisslinger, Christian Münch, Klaus Scholich, Marco Sisignano

Cells. 2020 Jul; 9(7): 1740. Published online 2020 Jul 21. doi: 10.3390/cells9071740

PMCID:: PMC7409160

Article PDF–2.2M

Select item 61742453.

The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue

Katharina Kern, Stephan M. G. Schäfer, Jennifer Cohnen, Sandra Pierre, Tabea Osthues, Neda Tarighi, Stefan Hohmann, Nerea Ferreiros, Bernhard Brüne, Andreas Weigert, Gerd Geisslinger, Marco Sisignano, Klaus Scholich

Front Immunol. 2018; 9: 2261. Published online 2018 Oct 1. doi: 10.3389/fimmu.2018.02261

PMCID:: PMC6174245

Article PDF–3.2M

Select item 49759504.

G2A signaling dampens colitic inflammation via production of IFNγ

S. Courtney Frasch, Eóin N. McNamee, Douglas Kominsky, Paul Jedlicka, Claudia Jakubzick, Karin Zemski Berry, Matthias Mack, Glenn T. Furuta, James J. Lee, Peter M. Henson, Sean P. Colgan, Donna L. Bratton

J Immunol. Author manuscript; available in PMC 2017 Aug 15.

Published in final edited form as: J Immunol. 2016 Aug 15; 197(4): 1425–1434. Published online 2016 Jul 8. doi: 10.4049/jimmunol.1600264

PMCID:: PMC4975950

Article PDF–3.4M

Select item 30694155.

Signaling via Macrophage G2A Enhances Efferocytosis of Dying Neutrophils by Augmentation of Rac Activity

S. Courtney Frasch, Ruby F. Fernandez-Boyanapalli, Karin Zemski Berry, Christina C. Leslie, Joseph V. Bonventre, Robert C. Murphy, Peter M. Henson, Donna L. Bratton

J Biol Chem. 2011 Apr 8; 286(14): 12108–12122. Published online 2011 Feb 4. doi: 10.1074/jbc.M110.181800

PMCID:: PMC3069415

Article PDF–1.2M

Select item 28929796.

The G Protein–Coupled Receptor G2A: Involvement in Hepatic Lipid Metabolism and Gallstone Formation in Mice

Laura E. Johnson, Marc S. Elias, David T. Bolick, Marcus D. Skaflen, Richard M. Green, Catherine C. Hedrick

Hepatology. Author manuscript; available in PMC 2010 Jun 28.

Published in final edited form as: Hepatology. 2008 Oct; 48(4): 1138–1148. doi: 10.1002/hep.22433

PMCID:: PMC2892979

Article PDF–2.5M

Select item 26925757.

Deletion of the G2A receptor fails to attenuate experimental autoimmune encephalomyelitis

Inga Osmers, Sherry S. Smith, Brian W. Parks, Shaohua Yu, Roshni Srivastava, Jillian E. Wohler, Scott R. Barnum, Janusz H.S. Kabarowski

J Neuroimmunol. Author manuscript; available in PMC 2009 Jun 8.

Published in final edited form as: J Neuroimmunol. 2009 Feb 15; 207(1-2): 18–23. Published online 2009 Jan 9. doi: 10.1016/j.jneuroim.2008.11.008

PMCID:: PMC2692575

Article PDF–511K

Select item 10872318.

Lysophosphatidylcholine-induced Surface Redistribution Regulates Signaling of the Murine G Protein-coupled Receptor G2A

Li Wang, Caius G. Radu, Li V. Yang, Laurent A. Bentolila, Mireille Riedinger, Owen N. Witte

Mol Biol Cell. 2005 May; 16(5): 2234–2247. doi: 10.1091/mbc.E04-12-1044

PMCID:: PMC1087231

Article PDF–1.1M

Select item 3141709.

T cell chemotaxis to lysophosphatidylcholine through the G2A receptor

Caius G. Radu, Li V. Yang, Mireille Riedinger, Matthew Au, Owen N. Witte

Proc Natl Acad Sci U S A. 2004 Jan 6; 101(1): 245–250. Published online 2003 Dec 17. doi: 10.1073/pnas.2536801100

PMCID:: PMC314170

Article PDF–444K

Select item 970179810.

Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia

Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov, Junke Zheng, Mingyao Liu, Weiqiang Lu

Cell Death Dis. 2022 Nov; 13(11): 1004. Published online 2022 Nov 27. doi: 10.1038/s41419-022-05434-z

PMCID:: PMC9701798

Article PDF–5.5M

Select item 844933311.

The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages

Sri Murugan Poongkavithai Vadevoo, Gowri Rangaswamy Gunassekaran, ChaeEun Lee, NaHye Lee, Jiyoun Lee, Sehyun Chae, Jae-Yong Park, JaeHyung Koo, Byungheon Lee

Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2102434118. Published online 2021 Sep 9. doi: 10.1073/pnas.2102434118

PMCID:: PMC8449333

Article PDF–1.4M

Select item 647768312.

G2A Protects Mice against Sepsis by Modulating Kupffer Cell Activation: Cooperativity with Adenosine Receptor 2b

Hong-Mei Li, Ji Hye Jang, Jun-Sub Jung, Jiseon Shin, Chul O. Park, Yeon-Ja Kim, Won-Gyun Ahn, Ju-Suk Nam, Chang-Won Hong, Jongho Lee, Yu-Jin Jung, Jiang-Fan Chen, Katya Ravid, H. Thomas Lee, Won-Ki Huh, Janusz H. Kabarowski, Dong-Keun Song

J Immunol. Author manuscript; available in PMC 2019 Jul 15.

Published in final edited form as: J Immunol. 2019 Jan 15; 202(2): 527–538. Published online 2018 Dec 10. doi: 10.4049/jimmunol.1700783

PMCID:: PMC6477683

Article PDF–1.0M

Select item 525563013.

Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

Peiwen Chen, Hao Zuo, Hu Xiong, Matthew J. Kolar, Qian Chu, Alan Saghatelian, Daniel J. Siegwart, Yihong Wan

Proc Natl Acad Sci U S A. 2017 Jan 17; 114(3): 580–585. Published online 2017 Jan 3. doi: 10.1073/pnas.1614035114

PMCID:: PMC5255630

Article PDF–1.1M

Select item 360598714.

CD36, but not G2A, modulates efferocytosis, inflammation, and fibrosis following bleomycin-induced lung injury

Brian W. Parks, Leland L. Black, Kurt A. Zimmerman, Allison E. Metz, Chad Steele, Joanne E. Murphy-Ullrich, Janusz H. Kabarowski

J Lipid Res. 2013 Apr; 54(4): 1114–1123. doi: 10.1194/jlr.M035352

PMCID:: PMC3605987

Article PDF–1.3M

Select item 357606415.

Neutrophils Regulate Tissue Neutrophilia in Inflammation via the Oxidant-modified Lipid Lysophosphatidylserine

S. Courtney Frasch, Ruby F. Fernandez-Boyanapalli, Karin A. Zemski Berry, Robert C. Murphy, Christina C. Leslie, Jerry A. Nick, Peter M. Henson, Donna L. Bratton

J Biol Chem. 2013 Feb 15; 288(7): 4583–4593. Published online 2013 Jan 5. doi: 10.1074/jbc.M112.438507

PMCID:: PMC3576064

Article PDF–1.7M

Select item 504774616.

Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone

Wing Yin Cheng, HoangDinh Huynh, Peiwen Chen, Samuel Peña-Llopis, Yihong Wan

eLife. 2016; 5: e18501. Published online 2016 Oct 3. doi: 10.7554/eLife.18501

PMCID:: PMC5047746

Article PDF–1.3M

Select item 271680317.

G2A Deficiency in Mice Promotes Macrophage Activation and Atherosclerosis

David T. Bolick, Marcus D. Skaflen, Laura E. Johnson, Seong-Chun Kwon, Deborah Howatt, Alan Daugherty, Kodi S. Ravichandran, Catherine C. Hedrick

Circ Res. Author manuscript; available in PMC 2010 Feb 13.

Published in final edited form as: Circ Res. 2009 Feb 13; 104(3): 318–327. Published online 2008 Dec 23. doi: 10.1161/CIRCRESAHA.108.181131

PMCID:: PMC2716803

Article PDF–7.8M

Select item 267981118.

ApoE-Dependent Modulation of HDL and Atherosclerosis by G2A in LDL Receptor-Deficient Mice Independent of Bone Marrow-Derived Cells

Brian W. Parks, Roshni Srivastava, Shaohua Yu, Janusz H.S. Kabarowski

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2009 May 8.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4): 539–547. Published online 2009 Jan 22. doi: 10.1161/ATVBAHA.108.179937

PMCID:: PMC2679811

Article PDF–1.3M

Select item 258627919.

NADPH Oxidase-dependent Generation of Lysophosphatidylserine Enhances Clearance of Activated and Dying Neutrophils via G2A

S. Courtney Frasch, Karin Zemski Berry, Ruby Fernandez-Boyanapalli, Hyun-Sun Jin, Christina Leslie, Peter M. Henson, Robert C. Murphy, Donna L. Bratton

J Biol Chem. 2008 Nov 28; 283(48): 33736–33749. doi: 10.1074/jbc.M807047200

PMCID:: PMC2586279

Article PDF–1.4M

Select item 2283220.

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G₂/M

Zhigang Weng, Anne-Catherine Fluckiger, Sazuku Nisitani, Matthew I. Wahl, Lu Q. Le, Charity A. Hunter, Anthony A. Fernal, Michelle M. Le Beau, Owen N. Witte

Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21): 12334–12339. doi: 10.1073/pnas.95.21.12334