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Select item 107533731.

TXNIP aggravates cardiac fibrosis and dysfunction after myocardial infarction in mice by enhancing the TGFB1/Smad3 pathway and promoting NLRP3 inflammasome activation: TXNIP aggravates MI-induced cardiac remodelling

Yan Zhang, Jin Wang, Xuejiao Wang, Aiyun Li, Zhandong Lei, Dongxue Li, Dehai Xing, Yichao Zhang, Wanzhen Su, Xiangying Jiao

Acta Biochim Biophys Sin (Shanghai) 2023 Dec 25; 55(12): 1950–1960. Published online 2023 Oct 17. doi: 10.3724/abbs.2023150

PMCID:: PMC10753373

Article PDF–2.3M

Select item 104879772.

VDUP1 Deficiency Promotes the Severity of DSS-Induced Colitis in Mice by Inducing Macrophage Infiltration

Ki Hwan Park, Hyunju Lee, Hyoung-Chin Kim, Inpyo Choi, Sang-Bae Han, Jong Soon Kang

Int J Mol Sci. 2023 Sep; 24(17): 13584. Published online 2023 Sep 1. doi: 10.3390/ijms241713584

PMCID:: PMC10487977

Article PDF–3.7M

Select item 103382333.

Differential effects of sugar and fat on adipose tissue inflammation

Tracey Avequin, Kin H. Lau, Althea N. Waldhart, Hannah Guak, Holly Dykstra, Connie Krawczyk, Ning Wu

iScience. 2023 Jul 21; 26(7): 107163. Published online 2023 Jun 19. doi: 10.1016/j.isci.2023.107163

PMCID:: PMC10338233

Article PDF–5.4M

Select item 102373494.

Txnip Gene Knockout Ameliorated High-Fat Diet–Induced Cardiomyopathy Via Regulating Mitochondria Dynamics and Fatty Acid Oxidation

Aiyun Li, Yichao Zhang, Jin Wang, Yan Zhang, Wanzhen Su, Feng Gao, Xiangying Jiao

J Cardiovasc Pharmacol. 2023 Jun; 81(6): 423–433. Published online 2023 Jun 1. doi: 10.1097/FJC.0000000000001414

PMCID:: PMC10237349

Article PDF–1.2M

Select item 101648945.

Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP

Althea N. Waldhart, Kin H. Lau, Holly Dykstra, Tracey Avequin, Ning Wu

iScience. 2023 May 19; 26(5): 106538. Published online 2023 Apr 10. doi: 10.1016/j.isci.2023.106538

PMCID:: PMC10164894

Article PDF–5.2M

Select item 84499516.

Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue

Althea N. Waldhart, Brejnev Muhire, Ben Johnson, Dean Pettinga, Zachary B. Madaj, Emily Wolfrum, Holly Dykstra, Vanessa Wegert, J. Andrew Pospisilik, Xianlin Han, Ning Wu

Cell Rep. Author manuscript; available in PMC 2021 Sep 19.

Published in final edited form as: Cell Rep. 2021 Aug 3; 36(5): 109488. doi: 10.1016/j.celrep.2021.109488

PMCID:: PMC8449951

Article PDF–1.7M

Select item 81547467.

Txnip C247S mutation protects the heart against acute myocardial infarction

Yoshinobu Nakayama, Nobuhiro Mukai, Bing F. Wang, Kristen Yang, Parth Patwari, Richard N. Kitsis, Jun Yoshioka

J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: J Mol Cell Cardiol. 2021 Jun; 155: 36–49. Published online 2021 Feb 27. doi: 10.1016/j.yjmcc.2021.02.013

PMCID:: PMC8154746

Article PDF–2.1M

Select item 80815288.

AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

Yunlu Xue, Sean K Wang, Parimal Rana, Emma R West, Christin M Hong, Helian Feng, David M Wu, Constance L Cepko

eLife. 2021; 10: e66240. Published online 2021 Apr 13. doi: 10.7554/eLife.66240

PMCID:: PMC8081528

Article PDF–9.8M

Select item 75895349.

Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP)

Richard Kehm, Markus Jähnert, Stefanie Deubel, Tanina Flore, Jeannette König, Tobias Jung, Mandy Stadion, Wenke Jonas, Annette Schürmann, Tilman Grune, Annika Höhn

Redox Biol. 2020 Oct; 37: 101748. Published online 2020 Oct 7. doi: 10.1016/j.redox.2020.101748

PMCID:: PMC7589534

Article PDF–9.2M

Select item 749510710.

Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption

Anu Shah, Sezin Dagdeviren, Jordan P. Lewandowski, Angela B. Schmider, Elisabeth M. Ricci-Blair, Niranjana Natarajan, Henna Hundal, Hye Lim Noh, Randall H. Friedline, Charles Vidoudez, Jason K. Kim, Amy J. Wagers, Roy J. Soberman, Richard T. Lee

iScience. 2020 Sep 25; 23(9): 101521. Published online 2020 Sep 2. doi: 10.1016/j.isci.2020.101521

PMCID:: PMC7495107

Article PDF–4.2M

Select item 714218511.

Thioredoxin-Interacting Protein (TXNIP) Regulates Parkin/PINK1-mediated Mitophagy in Dopaminergic Neurons Under High-glucose Conditions: Implications for Molecular Links Between Parkinson’s Disease and Diabetes

Cun-Jin Su, Zhu Shen, Ru-Xiao Cui, Ya Huang, De-Lai Xu, Feng-Lun Zhao, Jie Pan, Ai-Ming Shi, Tong Liu, Yun-Li Yu

Neurosci Bull. 2020 Apr; 36(4): 346–358. Published online 2020 Jan 14. doi: 10.1007/s12264-019-00459-5

PMCID:: PMC7142185

Article PDF–2.9M

Select item 686118612.

Thioredoxin-Interacting Protein Promotes Phagosomal Acidification Upon Exposure to Escherichia coli Through Inflammasome-Mediated Caspase-1 Activation in Macrophages

Sung-Jin Yoon, Dong Hyun Jo, Seung-Ho Park, Jun-Young Park, Yoo-Kyung Lee, Moo-Seung Lee, Jeong-Ki Min, Haiyoung Jung, Tae-Don Kim, Suk Ran Yoon, Su Wol Chung, Jeong Hun Kim, Inpyo Choi, Young-Jun Park

Front Immunol. 2019; 10: 2636. Published online 2019 Nov 12. doi: 10.3389/fimmu.2019.02636

PMCID:: PMC6861186

Article PDF–4.8M

Select item 675982113.

HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection

Po-Chun Tseng, Chih-Feng Kuo, Miao-Huei Cheng, Shu-Wen Wan, Chiou-Feng Lin, Chih-Peng Chang, Yee-Shin Lin, Jiunn-Jong Wu, Chi-Chen Huang, Chia-Ling Chen

Front Immunol. 2019; 10: 2147. Published online 2019 Sep 18. doi: 10.3389/fimmu.2019.02147

PMCID:: PMC6759821

Article PDF–2.8M

Select item 465782514.

Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy

Anu Shah, Ling Xia, Elodie A.Y. Masson, Chloe Gui, Abdul Momen, Eric A. Shikatani, Mansoor Husain, Susan Quaggin, Rohan John, I.G. Fantus

J Am Soc Nephrol. 2015 Dec; 26(12): 2963–2977. Published online 2015 Apr 8. doi: 10.1681/ASN.2014050528

PMCID:: PMC4657825

Article

Select item 419968615.

Deletion of Thioredoxin Interacting Protein (TXNIP) Augments Hyperoxia-Induced Vaso-Obliteration in a Mouse Model of Oxygen Induced-Retinopathy

Mohammed A. Abdelsaid, Suraporn Matragoon, Adviye Ergul, Azza B. El-Remessy

PLoS One. 2014; 9(10): e110388. Published online 2014 Oct 16. doi: 10.1371/journal.pone.0110388

PMCID:: PMC4199686

Article PDF–1.5M

Select item 399084316.

Use of a Mouse In Vitro Fertilization Model to Understand the Developmental Origins of Health and Disease Hypothesis

Sky K. Feuer, Xiaowei Liu, Annemarie Donjacour, Wingka Lin, Rhodel K. Simbulan, Gnanaratnam Giritharan, Luisa Delle Piane, Kevin Kolahi, Kurosh Ameri, Emin Maltepe, Paolo F. Rinaudo

Endocrinology. 2014 May; 155(5): 1956–1969. Published online 2014 Jan 31. doi: 10.1210/en.2013-2081

PMCID:: PMC3990843

Article

Select item 398196917.

Thioredoxin-Interacting Protein (TXNIP) is a Biomechanical Regulator of Src Activity: Key Role in Endothelial Cell Stress Fiber Formation

Oded N. Spindel, Ryan Burke, Chen Yan, Bradford C. Berk

Circ Res. Author manuscript; available in PMC 2015 Mar 28.

Published in final edited form as: Circ Res. 2014 Mar 28; 114(7): 1125–1132. Published online 2014 Feb 10. doi: 10.1161/CIRCRESAHA.114.301315

PMCID:: PMC3981969

Article PDF–4.3M

Select item 386945018.

Thioredoxin-Interacting Protein Expression Is Required for VEGF-Mediated Angiogenic Signal in Endothelial Cells

Mohammed A. Abdelsaid, Suraporn Matragoon, Azza B. El-Remessy

Antioxid Redox Signal. 2013 Dec 20; 19(18): 2199–2212. doi: 10.1089/ars.2012.4761

PMCID:: PMC3869450

Article PDF–1.0M

Select item 382772519.

Thioredoxin 1 is Essential for Sodium Sulfide-Mediated Cardioprotection in the Setting of Heart Failure

Chad K. Nicholson, Jonathan P. Lambert, Jeffery D. Molkentin, Junichi Sadoshima, John W. Calvert

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Apr; 33(4): 10.1161/ATVBAHA.112.300484. Published online 2013 Jan 24. doi: 10.1161/ATVBAHA.112.300484

PMCID:: PMC3827725

Article PDF–2.7M

Select item 378975420.

TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

Young-Jun Park, Sung-Jin Yoon, Hyun-Woo Suh, Dong Oh Kim, Jeong-Ran Park, Haiyoung Jung, Tae-Don Kim, Suk Ran Yoon, Jeong-Ki Min, Hee-Jun Na, Seon-Jin Lee, Hee Gu Lee, Young Ho Lee, Hee-Bong Lee, Inpyo Choi

PLoS Pathog. 2013 Oct; 9(10): e1003646. Published online 2013 Oct 3. doi: 10.1371/journal.ppat.1003646