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Select item 89990751.

GABA_A Receptor-Stabilizing Protein Ubqln1 Affects Hyperexcitability and Epileptogenesis after Traumatic Brain Injury and in a Model of In Vitro Epilepsy in Mice

Tabea Kürten, Natascha Ihbe, Timo Ueberbach, Ute Distler, Malte Sielaff, Stefan Tenzer, Thomas Mittmann

Int J Mol Sci. 2022 Apr; 23(7): 3902. Published online 2022 Mar 31. doi: 10.3390/ijms23073902

PMCID:: PMC8999075

Article PDF–2.2M

Select item 75393882.

Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD

Shaoteng Wang, Micaela Tatman, Mervyn J. Monteiro

Acta Neuropathol Commun. 2020; 8: 164. Published online 2020 Oct 7. doi: 10.1186/s40478-020-01039-9

PMCID:: PMC7539388

Article PDF–18M

Select item 65228303.

Decreased expression of ubiquilin-1 following neonatal hypoxia-ischemic brain injury in mice

Li Luo, Yilin Liu, Xing Tu, Xuxin Ren, Wenyan Zhao, Jing Liu, Li Zhang, Weiqiang Chen, Pei Zhang, Weicai Wang, Lanhai Lü, Mengxia Wang

Mol Med Rep. 2019 Jun; 19(6): 4597–4602. Published online 2019 Apr 15. doi: 10.3892/mmr.2019.10168

PMCID:: PMC6522830

Article PDF–676K

Select item 57915274.

Overexpression of ubiquilin-1 alleviates Alzheimer’s disease-caused cognitive and motor deficits and reduces amyloid-β accumulation in mice

Oludotun O. Adegoke, Fangfang Qiao, Yanying Liu, Kirsty Longley, Shelley Feng, Hongmin Wang

J Alzheimers Dis. Author manuscript; available in PMC 2018 Jan 31.

Published in final edited form as: J Alzheimers Dis. 2017; 59(2): 575–590. doi: 10.3233/JAD-170173

PMCID:: PMC5791527

Article PDF–1.7M

Select item 54628865.

Enhanced proteostasis in post-ischemic stroke mouse brains by ubiquilin-1 promotes functional recovery

Yanying Liu, Fangfang Qiao, Hongmin Wang

Cell Mol Neurobiol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Cell Mol Neurobiol. 2017 Oct; 37(7): 1325–1329. Published online 2016 Dec 7. doi: 10.1007/s10571-016-0451-3

PMCID:: PMC5462886

Article PDF–770K

Select item 54082896.

Reduced body weight gain in ubiquilin‐1 transgenic mice is associated with increased expression of energy‐sensing proteins

Fangfang Qiao, Kirsty R. Longley, Shelley Feng, Sabrina Schnack, Hongbo Gao, Yifan Li, Evelyn H. Schlenker, Hongmin Wang

Physiol Rep. 2017 Apr; 5(8): e13260. Published online 2017 Apr 18. doi: 10.14814/phy2.13260

PMCID:: PMC5408289

Article PDF–1.0M

Select item 45207157.

Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis

Erik T. Sakowski, Stefan Koster, Cynthia Portal Celhay, Heidi S. Park, Elina Shrestha, Stefanie E. Hetzenecker, Katie Maurer, Ken Cadwell, Jennifer A. Philips

PLoS Pathog. 2015 Jul; 11(7): e1005076. Published online 2015 Jul 30. doi: 10.1371/journal.ppat.1005076

PMCID:: PMC4520715

Article PDF–2.6M

Select item 39535898.

Ubiquilin-1 Protects Cells from Oxidative Stress and Ischemic Stroke Caused Tissue Injury in Mice

Yanying Liu, Lanhai Lü, Casey L. Hettinger, Gaofeng Dong, Dong Zhang, Khosrow Rezvani, Xuejun Wang, Hongmin Wang

J Neurosci. 2014 Feb 19; 34(8): 2813–2821. doi: 10.1523/JNEUROSCI.3541-13.2014

PMCID:: PMC3953589

Article PDF–2.4M

Select item 103927399.

Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury

Yanping Li, Jingyuan Xu, Weiting Chen, Xingxing Wang, Zhibo Zhao, Yuqi Li, Linkun Zhang, Junkui Jiao, Qin Yang, Qiuying Ding, Ping Yang, Li Wei, Yao Chen, Yaxi Chen, Xiong Z. Ruan, Lei Zhao

Autophagy. 2023; 19(9): 2504–2519. Published online 2023 Apr 23. doi: 10.1080/15548627.2023.2196876

PMCID:: PMC10392739

Article PDF–8.0M

Select item 1038104210.

UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1

Haoxian Zhou, Chen Xie, Yujie Xie, Yunru He, Yanlian Chen, Canfeng Zhang, Yan Zhang, Yong Zhao, Haiying Liu

PLoS Genet. 2023 Jul; 19(7): e1010856. Published online 2023 Jul 18. doi: 10.1371/journal.pgen.1010856

PMCID:: PMC10381042

Article PDF–3.4M

Select item 880677511.

miR-337-5p promotes the development of cardiac hypertrophy by targeting Ubiquilin-1 (UBQLN1)

Ying Ding, Jingyu Wang, Jun Lu

Bioengineered. 2021; 12(1): 6771–6781. Published online 2021 Sep 13. doi: 10.1080/21655979.2021.1964892

PMCID:: PMC8806775

Article PDF–2.2M

Select item 327188712.

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1

Levi J. Beverly, William W. Lockwood, Parag P. Shah, Hediye Erdjument-Bromage, Harold Varmus

Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3): E119-E126. Published online 2012 Jan 10. doi: 10.1073/pnas.1119167109

PMCID:: PMC3271887

Article PDF–1.6M

Select item 295087513.

UBQLN1 interacts with SPEM1 and participates in spermiogenesis

Jianqiang Bao, Jie Zhang, Huili Zheng, Chen Xu, Wei Yan

Mol Cell Endocrinol. Author manuscript; available in PMC 2011 Oct 7.

Published in final edited form as: Mol Cell Endocrinol. 2010 Oct 7; 327(1-2): 89–97. Published online 2010 Jun 14. doi: 10.1016/j.mce.2010.06.006

PMCID:: PMC2950875

Article PDF–1.3M

Select item 335134514.

The Syk-binding Ubiquitin Ligase c-Cbl Mediates Signaling-dependent B Cell Receptor Ubiquitination and B Cell Receptor-mediated Antigen Processing and Presentation

Bhuvana Katkere, Sarah Rosa, James R. Drake

J Biol Chem. 2012 May 11; 287(20): 16636–16644. Published online 2012 Mar 26. doi: 10.1074/jbc.M112.357640

PMCID:: PMC3351345

Article PDF–3.1M

Select item 311788115.

The Ubiquitin-Like Protein PLIC-1 or Ubiquilin 1 Inhibits TLR3-Trif Signaling

Nabanita Biswas, Shufeng Liu, Tapani Ronni, Steven E. Aussenberg, Weiqun Liu, Takashi Fujita, Tianyi Wang

PLoS One. 2011; 6(6): e21153. Published online 2011 Jun 17. doi: 10.1371/journal.pone.0021153

PMCID:: PMC3117881

Article PDF–763K

Select item 290847216.

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

Cara Rothenberg, Deepa Srinivasan, Leann Mah, Susmita Kaushik, Corrine M. Peterhoff, Janet Ugolino, Shengyun Fang, Ana Maria Cuervo, Ralph A. Nixon, Mervyn J. Monteiro

Hum Mol Genet. 2010 Aug 15; 19(16): 3219–3232. Published online 2010 Jun 7. doi: 10.1093/hmg/ddq231

PMCID:: PMC2908472

Article PDF–663K

Select item 263731417.

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

Elsa-Noah N'Diaye, Kimberly K Kajihara, Ivy Hsieh, Hiroshi Morisaki, Jayanta Debnath, Eric J Brown

EMBO Rep. 2009 Feb; 10(2): 173–179. Published online 2009 Jan 16. doi: 10.1038/embor.2008.238

PMCID:: PMC2637314

Article PDF–1.3M

Select item 391400118.

Unbiased Screen Reveals Ubiquilin-1 and -2 Highly Associated with Huntingtin Inclusions

Nicola J. Rutherford, Jada Lewis, Amy K. Clippinger, Michael A. Thomas, Jennifer Adamson, Pedro E. Cruz, Ashley Cannon, Guilian Xu, Todd E. Golde, Gerry Shaw, David R. Borchelt, Benoit I. Giasson

Brain Res. Author manuscript; available in PMC 2014 Aug 2.

Published in final edited form as: Brain Res. 2013 Aug 2; 1524: 62–73. Published online 2013 Jun 15. doi: 10.1016/j.brainres.2013.06.006

PMCID:: PMC3914001

Article PDF–1.9M

Select item 937686119.

RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control

Harihar Milaganur Mohan, Hanna Trzeciakiewicz, Amit Pithadia, Emily V. Crowley, Regina Pacitto, Nathaniel Safren, Bryce Trotter, Chengxin Zhang, Xiaogen Zhou, Yang Zhang, Venkatesha Basrur, Henry L. Paulson, Lisa M. Sharkey

Cell Mol Life Sci. Author manuscript; available in PMC 2022 Aug 15.

Published in final edited form as: Cell Mol Life Sci. 2022 Mar 5; 79(3): 176. Published online 2022 Mar 5. doi: 10.1007/s00018-022-04170-z

PMCID:: PMC9376861

Article PDF–2.7M

Select item 500381620.

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

Roland Hjerpe, John S. Bett, Matthew J. Keuss, Alexandra Solovyova, Thomas G. McWilliams, Clare Johnson, Indrajit Sahu, Joby Varghese, Nicola Wood, Melanie Wightman, Georgina Osborne, Gillian P. Bates, Michael H. Glickman, Matthias Trost, Axel Knebel, Francesco Marchesi, Thimo Kurz

Cell. 2016 Aug 11; 166(4): 935–949. doi: 10.1016/j.cell.2016.07.001