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Select item 108442911.

Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes

Linda Große-Segerath, Paula Follert, Kristina Behnke, Julia Ettich, Tobias Buschmann, Philip Kirschner, Sonja Hartwig, Stefan Lehr, Mortimer Korf-Klingebiel, Daniel Eberhard, Nadja Lehwald-Tywuschik, Hadi Al-Hasani, Wolfram Trudo Knoefel, Stefan Heinrich, Bodo Levkau, Kai C. Wollert, Jürgen Scheller, Eckhard Lammert

Nat Commun. 2024; 15: 1076. Published online 2024 Feb 5. doi: 10.1038/s41467-024-44760-y

PMCID:: PMC10844291

Article PDF–4.3M

Select item 88068042.

Identification of the correlations between interleukin-27 (IL-27) and immune-inflammatory imbalance in preterm birth

Yuxin Ran, Dongni Huang, Youwen Mei, Zheng Liu, Yunqian Zhou, Jie He, Hanwen Zhang, Nanlin Yin, Hongbo Qi

Bioengineered. 2021; 12(1): 3201–3218. Published online 2021 Jul 5. doi: 10.1080/21655979.2021.1945894

PMCID:: PMC8806804

Article PDF–4.0M

Select item 85616913.

Altered peripheral B lymphocyte homeostasis and functions mediated by IL‐27 via activating the mammalian target of rapamycin signaling pathway in patients with rheumatoid arthritis

Yawei Tang, Ziran Bai, Jingjing Qi, Zhimin Lu, Ahmad, Guan Wang, Minli Jin, Bing Wang, Haifeng Chen, Xia Li

Clin Exp Immunol. 2021 Dec; 206(3): 354–365. Published online 2021 Oct 5. doi: 10.1111/cei.13663

PMCID:: PMC8561691

Article PDF–1.8M

Select item 69015224.

Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum

Valeriu Bortnov, Marco Tonelli, Woonghee Lee, Ziqing Lin, Douglas S. Annis, Omar N. Demerdash, Alex Bateman, Julie C. Mitchell, Ying Ge, John L. Markley, Deane F. Mosher

Nat Commun. 2019; 10: 5612. Published online 2019 Dec 9. doi: 10.1038/s41467-019-13577-5

PMCID:: PMC6901522

Article PDF–4.6M

Select item 68795285.

Crystal structure and receptor-interacting residues of MYDGF — a protein mediating ischemic tissue repair

Rebecca Ebenhoch, Abbas Akhdar, Marc R. Reboll, Mortimer Korf-Klingebiel, Priyanka Gupta, Julie Armstrong, Yining Huang, Lee Frego, Irina Rybina, John Miglietta, Anton Pekcec, Kai C. Wollert, Herbert Nar

Nat Commun. 2019; 10: 5379. Published online 2019 Nov 26. doi: 10.1038/s41467-019-13343-7

PMCID:: PMC6879528

Article PDF–1.8M

Select item 19068086.

The identification and characterization of a novel protein, c19orf10, in the synovium

Tracey Weiler, Qiujiang Du, Oleg Krokhin, Werner Ens, Ken Standing, Hani El-Gabalawy, John A Wilkins

Arthritis Res Ther. 2007; 9(2): R30. Published online 2007 Mar 15. doi: 10.1186/ar2145

PMCID:: PMC1906808

Article PDF–1.3M

Select item 103584397.

rhMYDGF Alleviates I/R-induced Kidney Injury by Inhibiting Inflammation and Apoptosis via the Akt Pathway

Jingwen Wang, Ruiyang Ma, Ying Wang, Shucong Zhang, Jiale Wang, Jin Zheng, Wujun Xue, Xiaoming Ding

Transplantation. 2023 Aug; 107(8): 1729–1739. Published online 2023 Jul 20. doi: 10.1097/TP.0000000000004497

PMCID:: PMC10358439

Article PDF–3.5M

Select item 76810978.

Hypoxia-induced myeloid derived growth factor promotes hepatocellular carcinoma progression through remodeling tumor microenvironment

Xu Wang, Jie Mao, Tao Zhou, Xingyi Chen, Haoyang Tu, Jinyan Ma, Yixuan Li, Yushi Ding, Yong Yang, Hongxi Wu, Xinying Tang

Theranostics. 2021; 11(1): 209–221. Published online 2021 Jan 1. doi: 10.7150/thno.49327

PMCID:: PMC7681097

Article PDF–1.9M

Select item 61099409.

Myeloid-derived growth factor is a resident endoplasmic reticulum protein

Valeriu Bortnov, Douglas S. Annis, Frances J. Fogerty, Karina T. Barretto, Keren B. Turton, Deane F. Mosher

J Biol Chem. 2018 Aug 24; 293(34): 13166–13175. Published online 2018 Jun 28. doi: 10.1074/jbc.AC118.002052

PMCID:: PMC6109940

Article PDF–2.8M

Select item 361543310.

PKCε regulates ATF2 availability to alter mitochondrial permeability following genotoxic stress

Eric Lau, Harriet Kluger, Tal Varsano, KiYoung Lee, Immo Scheffler, David L. Rimm, Trey Ideker, Ze’ev A. Ronai

Cell. Author manuscript; available in PMC 2013 Apr 3.

Published in final edited form as: Cell. 2012 Feb 3; 148(3): 543–555. doi: 10.1016/j.cell.2012.01.016

PMCID:: PMC3615433

Article PDF–5.3M

Select item 649858511.

Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes

Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou

Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4

PMCID:: PMC6498585

Article PDF–6.9M

Select item 962912112.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Article PDF–8.1M

Select item 895155613.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Article PDF–4.4M

Select item 683185114.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Article PDF–9.8M

Select item 923162315.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Article PDF–6.0M

Select item 756688116.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Article PDF–4.8M

Select item 739233417.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Article PDF–2.7M

Select item 917141118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Article PDF–1.9M

Select item 855290719.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Article PDF–3.9M

Select item 927928520.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Article PDF–2.5M

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