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Select item 101728361.

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder

Elizabeth A. Werren, Alba Guxholli, Natasha Jones, Matias Wagner, Iris Hannibal, Jorge L. Granadillo, Amanda V. Tyndall, Amanda Moccia, Ryan Kuehl, Kristin M. Levandoski, Debra L. Day-Salvatore, Marsha Wheeler, University of Washington Center for Mendelian Genomics, Jessica X. Chong, Michael J. Bamshad, A. Micheil Innes, Tyler Mark Pierson, Joel P. Mackay, Stephanie L. Bielas, Donna M. Martin

HGG Adv. 2023 Jul 13; 4(3): 100198. Published online 2023 Apr 20. doi: 10.1016/j.xhgg.2023.100198

PMCID:: PMC10172836

Article PDF–2.9M

Select item 74922622.

A shared genetic contribution to breast cancer and schizophrenia

Donghao Lu, Jie Song, Yi Lu, Katja Fall, Xu Chen, Fang Fang, Mikael Landén, Christina M. Hultman, Kamila Czene, Patrick Sullivan, Rulla M. Tamimi, Unnur A. Valdimarsdóttir

Nat Commun. 2020; 11: 4637. Published online 2020 Sep 15. doi: 10.1038/s41467-020-18492-8

PMCID:: PMC7492262

Article PDF–1.0M

Select item 87003273.

p66α Suppresses Breast Cancer Cell Growth and Migration by Acting as Co-Activator of p53

Qun Zhang, Yihong Zhang, Jie Zhang, Dan Zhang, Mengying Li, Han Yan, Hui Zhang, Liwei Song, Jiamin Wang, Zhaoyuan Hou, Yunhai Yang, Xiuqun Zou

Cells. 2021 Dec; 10(12): 3593. Published online 2021 Dec 20. doi: 10.3390/cells10123593

PMCID:: PMC8700327

Article PDF–4.4M

Select item 66425044.

Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis

Yao Yao, Xinyuan Chen, Hong Yang, Wei Chen, Yichun Qian, Zhongyi Yan, Tian Liao, Weiping Yao, Wenlan Wu, Tonghua Yu, Yun Chen, Yuan Zhang

J Exp Clin Cancer Res. 2019; 38: 318. Published online 2019 Jul 19. doi: 10.1186/s13046-019-1321-x

Correction in:: J Exp Clin Cancer Res. 2020; 39: 56.

PMCID:: PMC6642504

Article PDF–7.5M

Select item 93744675.

lncKRT16P6 promotes tongue squamous cell carcinoma progression by sponging miR-3180 and regulating GATAD2A expression

Mi Zhang, Ling Wu, Xudong Wang, Jiang Chen

Int J Oncol. 2022 Sep; 61(3): 111. Published online 2022 Jul 28. doi: 10.3892/ijo.2022.5401

PMCID:: PMC9374467

Article PDF–8.4M

Select item 81053266.

Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period

Arnaud Beddok, Gaëlle Pérot, Sophie Le Guellec, Noémie Thebault, Alexandre Coutte, Henri Sevestre, Bruno Chauffert, Frédéric Chibon

Sci Rep. 2021; 11: 9765. Published online 2021 May 7. doi: 10.1038/s41598-021-88671-0

PMCID:: PMC8105326

Article PDF–3.6M

Select item 43810757.

An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex

Megha A. Desai, Heather D. Webb, Leander M. Sinanan, J. Neel Scarsdale, Ninad M. Walavalkar, Gordon D. Ginder, David C. Williams, Jr

Nucleic Acids Res. 2015 Mar 31; 43(6): 3100–3113. Published online 2015 Mar 9. doi: 10.1093/nar/gkv168

PMCID:: PMC4381075

Article PDF–3.0M

Select item 35615608.

Unique Features of the Anti-parallel, Heterodimeric Coiled-coil Interaction between Methyl-cytosine Binding Domain 2 (MBD2) Homologues and GATA Zinc Finger Domain Containing 2A (GATAD2A/p66α)

Ninad M. Walavalkar, Nathaniel Gordon, David C. Williams, Jr.

J Biol Chem. 2013 Feb 1; 288(5): 3419–3427. Published online 2012 Dec 13. doi: 10.1074/jbc.M112.431346

PMCID:: PMC3561560

Article PDF–2.0M

Select item 14891109.

SUMO Modification Enhances p66-Mediated Transcriptional Repression of the Mi-2/NuRD Complex

Zihua Gong, Marc Brackertz, Rainer Renkawitz

Mol Cell Biol. 2006 Jun; 26(12): 4519–4528. doi: 10.1128/MCB.00409-06

PMCID:: PMC1489110

Article PDF–495K

Select item 804325210.

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

Jia Z. Shen, Zhixin Qiu, Qiulian Wu, Darren Finlay, Guillermina Garcia, Dahui Sun, Juha Rantala, William Barshop, Jennifer L. Hope, Ryan C. Gimple, Olle Sangfelt, Linda M. Bradley, James Wohlschlegel, Jeremy N. Rich, Charles Spruck

Cell. Author manuscript; available in PMC 2021 Apr 13.

Published in final edited form as: Cell. 2021 Jan 21; 184(2): 352–369.e23. Published online 2020 Dec 23. doi: 10.1016/j.cell.2020.11.042

PMCID:: PMC8043252

Article PDF–3.8M

Select item 133198311.

p66α and p66β of the Mi-2/NuRD complex mediate MBD2 and histone interaction

Marc Brackertz, Zihua Gong, Jörg Leers, Rainer Renkawitz

Nucleic Acids Res. 2006; 34(2): 397–406. Published online 2006 Jan 13. doi: 10.1093/nar/gkj437

PMCID:: PMC1331983

Article PDF–454K

Select item 417260112.

The Chromatin Remodeling Factor CHD5 Is a Transcriptional Repressor of WEE1

Jinhua Quan, Guillaume Adelmant, Jarrod A. Marto, A. Thomas Look, Timur Yusufzai

PLoS One. 2014; 9(9): e108066. Published online 2014 Sep 23. doi: 10.1371/journal.pone.0108066

PMCID:: PMC4172601

Article PDF–580K

Select item 604237013.

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression

Jian Ma, Kun Chang, Jingtao Peng, Qing Shi, Hualei Gan, Kun Gao, Kai Feng, Fujiang Xu, Hailiang Zhang, Bo Dai, Yao Zhu, Guohai Shi, Yijun Shen, Yiping Zhu, Xiaojian Qin, Yao Li, Pingzhao Zhang, Dingwei Ye, Chenji Wang

J Exp Clin Cancer Res. 2018; 37: 145. Published online 2018 Jul 11. doi: 10.1186/s13046-018-0809-0

PMCID:: PMC6042370

Article PDF–5.2M

Select item 31692014.

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Yi Zhang, Huck-Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Adrian Bird, Danny Reinberg

Genes Dev. 1999 Aug 1; 13(15): 1924–1935. doi: 10.1101/gad.13.15.1924

PMCID:: PMC316920

Article PDF–2.3M

Select item 340218315.

NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

Nicola Reynolds, Paulina Latos, Antony Hynes-Allen, Remco Loos, Donna Leaford, Aoife O'Shaughnessy, Olukunbi Mosaku, Jason Signolet, Philip Brennecke, Tüzer Kalkan, Ita Costello, Peter Humphreys, William Mansfield, Kentaro Nakagawa, John Strouboulis, Axel Behrens, Paul Bertone, Brian Hendrich

Cell Stem Cell. 2012 May 4; 10(5): 583–594. doi: 10.1016/j.stem.2012.02.020

PMCID:: PMC3402183

Article PDF–1.3M

Select item 282446016.

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development

Annarita Miccio, Yuhuan Wang, Wei Hong, Gregory D Gregory, Hongxin Wang, Xiang Yu, John K Choi, Suresh Shelat, Wei Tong, Mortimer Poncz, Gerd A Blobel

EMBO J. 2010 Jan 20; 29(2): 442–456. Published online 2009 Nov 19. doi: 10.1038/emboj.2009.336

PMCID:: PMC2824460

Article PDF–1.2M

Select item 134703517.

MBD2/NuRD and MBD3/NuRD, Two Distinct Complexes with Different Biochemical and Functional Properties

Xavier Le Guezennec, Michiel Vermeulen, Arie B. Brinkman, Wieteke A. M. Hoeijmakers, Adrian Cohen, Edwin Lasonder, Hendrik G. Stunnenberg

Mol Cell Biol. 2006 Feb; 26(3): 843–851. doi: 10.1128/MCB.26.3.843-851.2006

PMCID:: PMC1347035

Article PDF–321K

Select item 824686318.

Cross‐linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex

Cornelia G. Spruijt, Cathrin Gräwe, Simone C. Kleinendorst, Marijke P. A. Baltissen, Michiel Vermeulen

FEBS J. 2021 May; 288(10): 3231–3245. Published online 2020 Dec 14. doi: 10.1111/febs.15650

PMCID:: PMC8246863

Article PDF–3.1M

Select item 549871719.

Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP

Sara Contreras-Martos, Alessandro Piai, Simone Kosol, Mihaly Varadi, Angela Bekesi, Pierre Lebrun, Alexander N. Volkov, Kris Gevaert, Roberta Pierattelli, Isabella C. Felli, Peter Tompa

Sci Rep. 2017; 7: 4676. Published online 2017 Jul 5. doi: 10.1038/s41598-017-04611-x

PMCID:: PMC5498717

Article PDF–3.7M

Select item 445124320.

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics

Serena Nicolai, Silvia Filippi, Manuela Caputo, Lubos Cipak, Juraj Gregan, Gustav Ammerer, Mattia Frontini, Daniela Willems, Giorgio Prantera, Adayabalam S. Balajee, Luca Proietti-De-Santis

PLoS One. 2015; 10(6): e0128558. Published online 2015 Jun 1. doi: 10.1371/journal.pone.0128558

PMCID:: PMC4451243

Article PDF–2.6M

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