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Items: 1 to 20 of 28

1.
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA
Meicen Zhou, Wenbao Lu, Bingwei Li, Xiaochen Yuan, Mingming Liu, Jianqun Han, Xueting Liu, Ailing Li
Int J Biol Sci. 2021; 17(11): 2884–2898. Published online 2021 Jul 13. doi: 10.7150/ijbs.59891
PMCID:
PMC8326130
ArticlePDF–2.7M
2.
Structure of human Roquin-2 and its complex with constitutive-decay element RNA
Shunya Sakurai, Umeharu Ohto, Toshiyuki Shimizu
Acta Crystallogr F Struct Biol Commun. 2015 Aug 1; 71(Pt 8): 1048–1054. Published online 2015 Jul 29. doi: 10.1107/S2053230X15011887
PMCID:
PMC4528940
ArticlePDF–1.4M
3.
Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor Roquin2
Jaewoo Choi, Kyutae Lee, Kristin Ingvarsdottir, Roberto Bonasio, Anita Saraf, Laurence Florens, Michael P. Washburn, Saber Tadros, Michael R. Green, Luca Busino
Nat Cell Biol. Author manuscript; available in PMC 2018 Oct 25.
Published in final edited form as: Nat Cell Biol. 2018 May; 20(5): 586–596. Published online 2018 Apr 25. doi: 10.1038/s41556-018-0084-5
PMCID:
PMC5926793
ArticlePDF–1.2M
4.
Identification of new high affinity targets for Roquin based on structural conservation
Johannes Braun, Sandra Fischer, Zhenjiang Z Xu, Hongying Sun, Dalia H Ghoneim, Anna T Gimbel, Uwe Plessmann, Henning Urlaub, David H Mathews, Julia E Weigand
Nucleic Acids Res. 2018 Dec 14; 46(22): 12109–12125. Published online 2018 Oct 8. doi: 10.1093/nar/gky908
PMCID:
PMC6294493
ArticlePDF–3.6M
5.
New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins
Qi Zhang, Lixin Fan, Feng Hou, Aiping Dong, Yun-Xing Wang, Yufeng Tong
Sci Rep. 2015; 5: 15660. Published online 2015 Oct 22. doi: 10.1038/srep15660
PMCID:
PMC4614863
ArticlePDF–1.5M
6.
Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks
Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson
Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162
PMCID:
PMC3394952
ArticlePDF–3.3M
7.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson
Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109
PMCID:
PMC2765280
ArticlePDF–425K
8.
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
Yasuhiro Murakawa, Michael Hinz, Janina Mothes, Anja Schuetz, Michael Uhl, Emanuel Wyler, Tomoharu Yasuda, Guido Mastrobuoni, Caroline C. Friedel, Lars Dölken, Stefan Kempa, Marc Schmidt-Supprian, Nils Blüthgen, Rolf Backofen, Udo Heinemann, Jana Wolf, Claus Scheidereit, Markus Landthaler
Nat Commun. 2015; 6: 7367. Published online 2015 Jul 14. doi: 10.1038/ncomms8367
PMCID:
PMC4510711
ArticlePDF–3.2M
9.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
ArticlePDF–3.7M
10.
Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B
Morag R. Hunter, Geoffrey G. Hesketh, Tomasz H. Benedyk, Anne-Claude Gingras, Stephen C. Graham
J Mol Biol. 2018 Jul 6; 430(14): 2153–2163. doi: 10.1016/j.jmb.2018.05.019
PMCID:
PMC6005816
ArticlePDF–1.6M
11.
Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53
Yafei Guo, Qin Li, Gang Zhao, Jie Zhang, Hang Yuan, Tianyu Feng, Deqiong Ou, Rui Gu, Siqi Li, Kai Li, Ping Lin
Cell Death Dis. 2021 Oct; 12(10): 945. Published online 2021 Oct 14. doi: 10.1038/s41419-021-04208-3
PMCID:
PMC8516922
ArticlePDF–8.2M
12.
Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells
Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney
Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240
PMCID:
PMC5098042
ArticlePDF–1.9M
13.
PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation
Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino
Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912
PMCID:
PMC6226225
ArticlePDF–1.7M
14.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
ArticlePDF–4.0M
15.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
ArticlePDF–2.1M
16.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
ArticlePDF–2.8M
17.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
ArticlePDF–8.2M
18.
Ubiquitin-mediated proteolysis of HuR by heat shock
Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe
EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67
PMCID:
PMC2683047
ArticlePDF–1.4M
19.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
ArticlePDF–3.7M
20.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
ArticlePDF–3.2M

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