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Select item 101260081.

CHST2-mediated sulfation of MECA79 antigens is critical for breast cancer cell migration and metastasis

Dan Zhang, Yihong Zhang, Xiuqun Zou, Mengying Li, Hui Zhang, Yaning Du, Jiamin Wang, Chicheng Peng, Chunyan Dong, Zhaoyuan Hou

Cell Death Dis. 2023 Apr; 14(4): 288. Published online 2023 Apr 24. doi: 10.1038/s41419-023-05797-x

PMCID:: PMC10126008

Article PDF–7.7M

Select item 36925292.

Ablation of Keratan Sulfate Accelerates Early Phase Pathogenesis of ALS

Kenichi Hirano, Tomohiro Ohgomori, Kazuyoshi Kobayashi, Fumiaki Tanaka, Tomohiro Matsumoto, Takamitsu Natori, Yukihiro Matsuyama, Kenji Uchimura, Kazuma Sakamoto, Hideyuki Takeuchi, Akihiro Hirakawa, Akio Suzumura, Gen Sobue, Naoki Ishiguro, Shiro Imagama, Kenji Kadomatsu

PLoS One. 2013; 8(6): e66969. Published online 2013 Jun 25. doi: 10.1371/journal.pone.0066969

PMCID:: PMC3692529

Article PDF–15M

Select item 66326053.

N-Acetylglucosamine 6-O-Sulfotransferase-1-Deficient Mice Show Better Functional Recovery after Spinal Cord Injury

Zenya Ito, Kazuma Sakamoto, Shiro Imagama, Yukihiro Matsuyama, Haoqian Zhang, Kenichi Hirano, Kei Ando, Toshihide Yamashita, Naoki Ishiguro, Kenji Kadomatsu

J Neurosci. 2010 Apr 28; 30(17): 5937–5947. doi: 10.1523/JNEUROSCI.2570-09.2010

PMCID:: PMC6632605

Article PDF–3.1M

Select item 39020944.

KSGal6ST Is Essential for the 6-Sulfation of Galactose within Keratan Sulfate in Early Postnatal Brain

Hitomi Hoshino, Tahmina Foyez, Shiori Ohtake-Niimi, Yoshiko Takeda-Uchimura, Makoto Michikawa, Kenji Kadomatsu, Kenji Uchimura

J Histochem Cytochem. 2014 Feb; 62(2): 145–156. doi: 10.1369/0022155413511619

PMCID:: PMC3902094

Article PDF–1.2M

Select item 30923575.

Essential role of peripheral node addressin in lymphocyte homing to nasal-associated lymphoid tissues and allergic immune responses

Yukari Ohmichi, Jotaro Hirakawa, Yasuyuki Imai, Minoru Fukuda, Hiroto Kawashima

J Exp Med. 2011 May 9; 208(5): 1015–1025. doi: 10.1084/jem.20101786

PMCID:: PMC3092357

Article PDF–2.3M

Select item 15338576.

Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis

Jiwei Yang, Steven D Rosen, Philip Bendele, Stefan Hemmerich

BMC Immunol. 2006; 7: 12. Published online 2006 Jun 13. doi: 10.1186/1471-2172-7-12

PMCID:: PMC1533857

Article PDF–631K

Select item 59774397.

Role of MAdCAM-1-Expressing High Endothelial Venule-Like Vessels in Colitis Induced in Mice Lacking Sulfotransferases Catalyzing L-Selectin Ligand Biosynthesis

Shulin Low, Jotaro Hirakawa, Hitomi Hoshino, Kenji Uchimura, Hiroto Kawashima, Motohiro Kobayashi

J Histochem Cytochem. 2018 Jun; 66(6): 415–425. Published online 2018 Jan 19. doi: 10.1369/0022155417753363

PMCID:: PMC5977439

Article PDF–1.8M

Select item 53892698.

Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer’s pathology

Zui Zhang, Yoshiko Takeda-Uchimura, Tahmina Foyez, Shiori Ohtake-Niimi, Narentuya, Hiroyasu Akatsu, Kazuchika Nishitsuji, Makoto Michikawa, Tony Wyss-Coray, Kenji Kadomatsu, Kenji Uchimura

Proc Natl Acad Sci U S A. 2017 Apr 4; 114(14): E2947–E2954. Published online 2017 Mar 20. doi: 10.1073/pnas.1615036114

PMCID:: PMC5389269

Article PDF–1.5M

Select item 105142859.

A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses

Wei Liu, Wei Xiong, Wenxin Liu, Jotaro Hirakawa, Hiroto Kawashima

Sci Rep. 2023; 13: 15740. Published online 2023 Sep 21. doi: 10.1038/s41598-023-43017-w

PMCID:: PMC10514285

Article PDF–5.2M

Select item 641629010.

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain

Narentuya, Yoshiko Takeda-Uchimura, Tahmina Foyez, Zui Zhang, Tomoya O. Akama, Hirokazu Yagi, Koichi Kato, Yukio Komatsu, Kenji Kadomatsu, Kenji Uchimura

Sci Rep. 2019; 9: 4387. Published online 2019 Mar 13. doi: 10.1038/s41598-019-40901-2

PMCID:: PMC6416290

Article PDF–1.8M

Select item 355550411.

KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing

Michael L Patnode, Shin-Yi Yu, Chu-Wen Cheng, Ming-Yi Ho, Lotten Tegesjö, Keiichiro Sakuma, Kenji Uchimura, Kay-Hooi Khoo, Reiji Kannagi, Steven D Rosen

Glycobiology. 2013 Mar; 23(3): 381–394. Published online 2012 Dec 18. doi: 10.1093/glycob/cws166

PMCID:: PMC3555504

Article PDF–1.0M

Select item 282546912.

Sulfation of Colonic Mucins by N-Acetylglucosamine 6-O-Sulfotransferase-2 and Its Protective Function in Experimental Colitis in Mice

Yuki Tobisawa, Yasuyuki Imai, Minoru Fukuda, Hiroto Kawashima

J Biol Chem. 2010 Feb 26; 285(9): 6750–6760. Published online 2009 Dec 16. doi: 10.1074/jbc.M109.067082

PMCID:: PMC2825469

Article PDF–3.3M

Select item 307058013.

Functional Contributions of N- and O-Glycans to L-Selectin Ligands in Murine and Human Lymphoid Organs

Hanayo Arata-Kawai, Mark S. Singer, Annette Bistrup, Annemieke van Zante, Yang-Qing Wang, Yuki Ito, Xingfeng Bao, Stefan Hemmerich, Minoru Fukuda, Steven D. Rosen

Am J Pathol. 2011 Jan; 178(1): 423–433. doi: 10.1016/j.ajpath.2010.11.009

PMCID:: PMC3070580

Article PDF–1.1M

Select item 300338714.

Novel Anti-carbohydrate Antibodies Reveal the Cooperative Function of Sulfated N- and O-Glycans in Lymphocyte Homing

Jotaro Hirakawa, Koichiro Tsuboi, Kaori Sato, Motohiro Kobayashi, Sota Watanabe, Atsushi Takakura, Yasuyuki Imai, Yuki Ito, Minoru Fukuda, Hiroto Kawashima

J Biol Chem. 2010 Dec 24; 285(52): 40864–40878. Published online 2010 Oct 7. doi: 10.1074/jbc.M110.167296

PMCID:: PMC3003387

Article PDF–6.1M

Select item 238414515.

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

Britt E. Anderson, Patricia A. Taylor, Jennifer M. McNiff, Dhanpat Jain, Anthony J. Demetris, Angela Panoskaltsis-Mortari, Ann Ager, Bruce R. Blazar, Warren D. Shlomchik, Mark J. Shlomchik

Blood. 2008 May 15; 111(10): 5242–5251. Prepublished online 2008 Feb 19. doi: 10.1182/blood-2007-09-107953