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Select item 66710701.

cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I

Achim Schmidtko, Wei Gao, Peter König, Sandra Heine, Roberto Motterlini, Peter Ruth, Jens Schlossmann, Doris Koesling, Ellen Niederberger, Irmgard Tegeder, Andreas Friebe, Gerd Geisslinger

J Neurosci. 2008 Aug 20; 28(34): 8568–8576. doi: 10.1523/JNEUROSCI.2128-08.2008

PMCID:: PMC6671070

Article PDF–578K

Select item 46993932.

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Robrecht Thoonen, Anje Cauwels, Kelly Decaluwe, Sandra Geschka, Robert E. Tainsh, Joris Delanghe, Tino Hochepied, Lode De Cauwer, Elke Rogge, Sofie Voet, Patrick Sips, Richard H. Karas, Kenneth D. Bloch, Marnik Vuylsteke, Johannes-Peter Stasch, Johan Van de Voorde, Emmanuel S. Buys, Peter Brouckaert

Nat Commun. 2015; 6: 8482. Published online 2015 Oct 7. doi: 10.1038/ncomms9482

PMCID:: PMC4699393

Article PDF–1.1M

Select item 44551113.

Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue

Linda S. Hoffmann, Jennifer Etzrodt, Lena Willkomm, Abhishek Sanyal, Ludger Scheja, Alexander W.C. Fischer, Johannes-Peter Stasch, Wilhelm Bloch, Andreas Friebe, Joerg Heeren, Alexander Pfeifer

Nat Commun. 2015; 6: 7235. Published online 2015 May 26. doi: 10.1038/ncomms8235

PMCID:: PMC4455111

Article PDF–1.1M

Select item 42890944.

SOLUBLE GUANYLATE CYCLASE IS REQUIRED FOR SYSTEMIC VASODILATION BUT NOT POSITIVE INOTROPY INDUCED BY NITROXYL (HNO) in the MOUSE

Guangshuo Zhu, Dieter Groneberg, Gautam Sikka, Daijiro Hori, Mark J. Ranek, Taishi Nakamura, Eiki Takimoto, Nazareno Paolocci, Dan E. Berkowitz, Andreas Friebe, David A. Kass

Hypertension. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Hypertension. 2015 Feb; 65(2): 385–392. Published online 2014 Dec 1. doi: 10.1161/HYPERTENSIONAHA.114.04285

PMCID:: PMC4289094

Article PDF–2.2M

Select item 39363735.

Correlation of cellular expression with function of NO-sensitive guanylyl cyclase in the murine lower urinary tract

Barbara Lies, Dieter Groneberg, Andreas Friebe

J Physiol. 2013 Nov 1; 591(Pt 21): 5365–5375. Published online 2013 Sep 9. doi: 10.1113/jphysiol.2013.262410

PMCID:: PMC3936373

Article PDF–1.6M

Select item 35775346.

Preserved fertility despite erectile dysfunction in mice lacking the nitric oxide receptor

Dieter Groneberg, Barbara Lies, Peter König, Ronald Jäger, Andreas Friebe

J Physiol. 2013 Jan 15; 591(Pt 2): 491–502. Published online 2012 Nov 5. doi: 10.1113/jphysiol.2012.245555

PMCID:: PMC3577534

Article PDF–1.8M

Select item 31863387.

Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation

Guoying Zhang, Binggang Xiang, Anping Dong, Radek C. Skoda, Alan Daugherty, Susan S. Smyth, Xiaoping Du, Zhenyu Li

Blood. 2011 Sep 29; 118(13): 3670–3679. Prepublished online 2011 Jul 29. doi: 10.1182/blood-2011-03-341107

PMCID:: PMC3186338

Article

Select item 18635128.

Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase

Andreas Friebe, Evanthia Mergia, Oliver Dangel, Alexander Lange, Doris Koesling

Proc Natl Acad Sci U S A. 2007 May 1; 104(18): 7699–7704. Published online 2007 Apr 23. doi: 10.1073/pnas.0609778104

PMCID:: PMC1863512

Article PDF–511K

Select item 85900749.

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev

Redox Biol. 2021 Dec; 48: 102179. Published online 2021 Nov 6. doi: 10.1016/j.redox.2021.102179

PMCID:: PMC8590074

Article PDF–6.7M

Select item 543098110.

Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Catarina Rippe, Baoyi Zhu, Katarzyna K. Krawczyk, Ed. Van Bavel, Sebastian Albinsson, Jonas Sjölund, Erik N. T. P. Bakker, Karl Swärd

Sci Rep. 2017; 7: 1334. Published online 2017 May 2. doi: 10.1038/s41598-017-01392-1

PMCID:: PMC5430981

Article PDF–4.3M

Select item 426733811.

Nitric oxide regulates synaptic transmission between spiny projection neurons

Yotam Sagi, Myriam Heiman, Jayms D. Peterson, Sergei Musatov, Mariangela Scarduzio, Stephen M. Logan, Michael G. Kaplitt, Dalton J. Surmeier, Nathaniel Heintz, Paul Greengard

Proc Natl Acad Sci U S A. 2014 Dec 9; 111(49): 17636–17641. Published online 2014 Nov 20. doi: 10.1073/pnas.1420162111

Correction in:: Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1811.

PMCID:: PMC4267338

Article PDF–1.3M

Select item 272421012.

sGCα₁β₁ attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Emmanuel S. Buys, Anje Cauwels, Michael J. Raher, Jonathan J. Passeri, Ion Hobai, Sharon M. Cawley, Kristen M. Rauwerdink, Helene Thibault, Patrick Y. Sips, Robrecht Thoonen, Marielle Scherrer-Crosbie, Fumito Ichinose, Peter Brouckaert, Kenneth D. Bloch

Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2): H654–H663. Published online 2009 Jun 5. doi: 10.1152/ajpheart.00367.2009

PMCID:: PMC2724210

Article

Select item 2711713.

Genomic organization of α1 and β1 subunits of the mammalian soluble guanylyl cyclase genes

I. G. Sharina, J. S. Krumenacker, E. Martin, F. Murad

Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20): 10878–10883. Published online 2000 Sep 12. doi: 10.1073/pnas.190331697

PMCID:: PMC27117

Article PDF–1.1M

Select item 426438214.

Pressure-overload induced subcellular re-localization/oxidation of soluble guanylate cyclase in the heart modulates enzyme stimulation

Emily J. Tsai, Yuchuan Liu, Norimichi Koitabashi, Djahida Bedja, Thomas Danner, Jean-Francois Jasmin, Michael P. Lisanti, Andreas Friebe, Eiki Takimoto, David A. Kass

Circ Res. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Circ Res. 2012 Jan 20; 110(2): 295–303. Published online 2011 Nov 17. doi: 10.1161/CIRCRESAHA.111.259242

PMCID:: PMC4264382

Article PDF–1.8M

Select item 403775515.

Endothelium-Derived Nitric Oxide Supports Renin Cell Recruitment Through the Nitric Oxide–Sensitive Guanylate Cyclase Pathway

Björn Neubauer, Katharina Machura, Ramona Kettl, Maria Luisa S. Sequeira Lopez, Andreas Friebe, Armin Kurtz

Hypertension. Author manuscript; available in PMC 2014 May 29.

Published in final edited form as: Hypertension. 2013 Feb; 61(2): 400–407. Published online 2013 Jan 7. doi: 10.1161/HYPERTENSIONAHA.111.00221

PMCID:: PMC4037755

Article PDF–1.2M

Select item 619144516.

A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis

Lai Wen, Susanne Feil, Markus Wolters, Martin Thunemann, Frank Regler, Kjestine Schmidt, Andreas Friebe, Marcus Olbrich, Harald Langer, Meinrad Gawaz, Cor de Wit, Robert Feil

Nat Commun. 2018; 9: 4301. Published online 2018 Oct 16. doi: 10.1038/s41467-018-06638-8