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Items: 1 to 20 of 41

1.
Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation
Wanjing Shang, Yong Jiang, Michael Boettcher, Kang Ding, Marianne Mollenauer, Zhongyi Liu, Xiaofeng Wen, Chang Liu, Piliang Hao, Suwen Zhao, Michael T. McManus, Lai Wei, Arthur Weiss, Haopeng Wang
Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): E4051–E4060. Published online 2018 Apr 9. doi: 10.1073/pnas.1801340115
PMCID:
PMC5924929
AbstractArticlePDF–2.0M
2.
GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis
Yue Xi, Tiange Zhang, Wei Sun, Ruobing Liang, Sridha Ganesh, Honglei Chen
Int J Mol Sci. 2022 Dec; 23(23): 15433. Published online 2022 Dec 6. doi: 10.3390/ijms232315433
PMCID:
PMC9737887
AbstractArticlePDF–6.3M
3.
Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1
Tamas Yelland, Anh Hoang Le, Savvas Nikolaou, Robert Insall, Laura Machesky, Shehab Ismail
Structure. 2021 Mar 4; 29(3): 226–237.e4. doi: 10.1016/j.str.2020.11.003
PMCID:
PMC7955166
AbstractArticle
4.
TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway
Yijian Zhang, Pengcheng Du, Yang Li, Qin Zhu, Xiaoling Song, Shibo Liu, Jiaqi Hao, Liguo Liu, Fatao Liu, Yunping Hu, Lin Jiang, Qiang Ma, Wei Lu, Yingbin Liu
Int J Biol Sci. 2020; 16(5): 739–751. Published online 2020 Jan 14. doi: 10.7150/ijbs.40516
PMCID:
PMC7019140
AbstractArticlePDF–3.0M
5.
LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress
Hongyang Huang, Yu-Man Tsui, Daniel Wai-Hung Ho, Clive Yik-Sham Chung, Karen Man-Fong Sze, Eva Lee, Gary Cheuk-Hang Cheung, Vanilla Xin Zhang, Xia Wang, Xueying Lyu, Irene Oi-Lin Ng
Hepatology. 2024 Feb; 79(2): 323–340. Published online 2023 Aug 7. doi: 10.1097/HEP.0000000000000523
PMCID:
PMC10789379
AbstractArticlePDF–2.4M
6.
CYRI (FAM49) proteins are local inhibitors of Scar/WAVE induced lamellipodia that bind directly to active Rac1
Loic Fort, Jose Batista, Peter A. Thomason, Heather J. Spence, Jamie A. Whitelaw, Luke Tweedy, Jennifer Greaves, Kirsty J. Martin, Kurt I. Anderson, Peter Brown, Sergio Lilla, Matthew P. Neilson, Petra Tafelmeyer, Sara Zanivan, Shehab Ismail, David M. Bryant, Nicholas C.O. Tomkinson, Luke H. Chamberlain, Grant S. Mastick, Robert H. Insall, Laura M. Machesky
Nat Cell Biol. Author manuscript; available in PMC 2019 Nov 19.
Published in final edited form as: Nat Cell Biol. 2018 Oct 1; 20(10): 1159–1171. Published online 2018 Sep 24. doi: 10.1038/s41556-018-0198-9
PMCID:
PMC6863750
AbstractArticlePDF–3.1M
7.
FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis
M S Chattaragada, C Riganti, M Sassoe, M Principe, M M Santamorena, C Roux, C Curcio, A Evangelista, P Allavena, R Salvia, B Rusev, A Scarpa, P Cappello, F Novelli
Oncogene. 2018 Feb 8; 37(6): 697–709. Published online 2017 Oct 23. doi: 10.1038/onc.2017.358
PMCID:
PMC5808099
AbstractArticlePDF–4.6M
8.
Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals
Katherine E. Williams, Olga Miroshnychenko, Eric B. Johansen, Richard K. Niles, Rajeshwari Sundaram, Kurunthachalam Kannan, Matthew Albertolle, Yan Zhou, Namrata Prasad, Penelope M. Drake, Linda C. Giudice, Steven C. Hall, H. Ewa Witkowska, Germaine M. Buck Louis, Susan J. Fisher
J Proteomics. Author manuscript; available in PMC 2015 Jun 15.
Published in final edited form as: J Proteomics. 2015 Jan 15; 113: 194–205. Published online 2014 Oct 13. doi: 10.1016/j.jprot.2014.09.015
PMCID:
PMC4467531
AbstractArticlePDF–1.1M
9.
MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences
Alberto L′Abbate, Doron Tolomeo, Ingrid Cifola, Marco Severgnini, Antonella Turchiano, Bartolomeo Augello, Gabriella Squeo, Pietro D′Addabbo, Debora Traversa, Giulia Daniele, Angelo Lonoce, Mariella Pafundi, Massimo Carella, Orazio Palumbo, Anna Dolnik, Dominique Muehlematter, Jacqueline Schoumans, Nadine Van Roy, Gianluca De Bellis, Giovanni Martinelli, Giuseppe Merla, Lars Bullinger, Claudia Haferlach, Clelia Tiziana Storlazzi
Leukemia. 2018; 32(10): 2152–2166. Published online 2018 Feb 22. doi: 10.1038/s41375-018-0033-0
Correction in:
Leukemia. 2018; 32(10): 2304.
PMCID:
PMC6170393
AbstractArticlePDF–2.4M
10.
Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder
Pingxing Xie, Henry R. Kranzler, Can Yang, Hongyu Zhao, Lindsay A. Farrer, Joel Gelernter
Biol Psychiatry. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Biol Psychiatry. 2013 Nov 1; 74(9): 10.1016/j.biopsych.2013.04.013. Published online 2013 May 28. doi: 10.1016/j.biopsych.2013.04.013
PMCID:
PMC3810148
AbstractArticlePDF–319K
11.
Multiple Loci Are Associated with White Blood Cell Phenotypes
Michael A. Nalls, David J. Couper, Toshiko Tanaka, Frank J. A. van Rooij, Ming-Huei Chen, Albert V. Smith, Daniela Toniolo, Neil A. Zakai, Qiong Yang, Andreas Greinacher, Andrew R. Wood, Melissa Garcia, Paolo Gasparini, Yongmei Liu, Thomas Lumley, Aaron R. Folsom, Alex P. Reiner, Christian Gieger, Vasiliki Lagou, Janine F. Felix, Henry Völzke, Natalia A. Gouskova, Alessandro Biffi, Angela Döring, Uwe Völker, Sean Chong, Kerri L. Wiggins, Augusto Rendon, Abbas Dehghan, Matt Moore, Kent Taylor, James G. Wilson, Guillaume Lettre, Albert Hofman, Joshua C. Bis, Nicola Pirastu, Caroline S. Fox, Christa Meisinger, Jennifer Sambrook, Sampath Arepalli, Matthias Nauck, Holger Prokisch, Jonathan Stephens, Nicole L. Glazer, L. Adrienne Cupples, Yukinori Okada, Atsushi Takahashi, Yoichiro Kamatani, Koichi Matsuda, Tatsuhiko Tsunoda, Toshihiro Tanaka, Michiaki Kubo, Yusuke Nakamura, Kazuhiko Yamamoto, Naoyuki Kamatani, Michael Stumvoll, Anke Tönjes, Inga Prokopenko, Thomas Illig, Kushang V. Patel, Stephen F. Garner, Brigitte Kuhnel, Massimo Mangino, Ben A. Oostra, Swee Lay Thein, Josef Coresh, H.-Erich Wichmann, Stephan Menzel, JingPing Lin, Giorgio Pistis, André G. Uitterlinden, Tim D. Spector, Alexander Teumer, Gudny Eiriksdottir, Vilmundur Gudnason, Stefania Bandinelli, Timothy M. Frayling, Aravinda Chakravarti, Cornelia M. van Duijn, David Melzer, Willem H. Ouwehand, Daniel Levy, Eric Boerwinkle, Andrew B. Singleton, Dena G. Hernandez, Dan L. Longo, Nicole Soranzo, Jacqueline C. M. Witteman, Bruce M. Psaty, Luigi Ferrucci, Tamara B. Harris, Christopher J. O'Donnell, Santhi K. Ganesh
PLoS Genet. 2011 Jun; 7(6): e1002113. Published online 2011 Jun 30. doi: 10.1371/journal.pgen.1002113
PMCID:
PMC3128114
AbstractArticlePDF–522K
12.
The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle
Hans-Jörg Warnatz, Dominic Schmidt, Thomas Manke, Ilaria Piccini, Marc Sultan, Tatiana Borodina, Daniela Balzereit, Wasco Wruck, Alexey Soldatov, Martin Vingron, Hans Lehrach, Marie-Laure Yaspo
J Biol Chem. 2011 Jul 1; 286(26): 23521–23532. Published online 2011 May 9. doi: 10.1074/jbc.M111.220178
PMCID:
PMC3123115
AbstractArticlePDF–2.2M
13.
A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)
David Melzer, John R. B. Perry, Dena Hernandez, Anna-Maria Corsi, Kara Stevens, Ian Rafferty, Fulvio Lauretani, Anna Murray, J. Raphael Gibbs, Giuseppe Paolisso, Sajjad Rafiq, Javier Simon-Sanchez, Hana Lango, Sonja Scholz, Michael N. Weedon, Sampath Arepalli, Neil Rice, Nicole Washecka, Alison Hurst, Angela Britton, William Henley, Joyce van de Leemput, Rongling Li, Anne B. Newman, Greg Tranah, Tamara Harris, Vijay Panicker, Colin Dayan, Amanda Bennett, Mark I. McCarthy, Aimo Ruokonen, Marjo-Riitta Jarvelin, Jack Guralnik, Stefania Bandinelli, Timothy M. Frayling, Andrew Singleton, Luigi Ferrucci
PLoS Genet. 2008 May; 4(5): e1000072. Published online 2008 May 9. doi: 10.1371/journal.pgen.1000072
PMCID:
PMC2362067
AbstractArticlePDF–442K
14.
Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies
Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis
Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749
PMCID:
PMC6283293
AbstractArticlePDF–1.9M
15.
Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network
Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang
Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195
PMCID:
PMC8864472
AbstractArticlePDF–3.6M
16.
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC
Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong
eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223
PMCID:
PMC6927754
AbstractArticlePDF–5.1M
17.
Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells
Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen
Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200
PMCID:
PMC310934
AbstractArticlePDF–1.3M
18.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway
Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan
J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5
PMCID:
PMC9102726
AbstractArticlePDF–15M
19.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
AbstractArticlePDF–1.4M
20.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Cell. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041
PMCID:
PMC8857049
AbstractArticlePDF–3.6M

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