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Select item 67950791.

SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation

Alain Sané, Lena Ahmarani, Edgard Delvin, Nikolas Auclair, Schohraya Spahis, Emile Levy

J Lipid Res. 2019 Oct; 60(10): 1755–1764. Published online 2019 Aug 13. doi: 10.1194/jlr.RA119000119

PMCID:: PMC6795079

Article PDF–1.1M

Select item 39242882.

The Endoplasmic Reticulum Coat Protein II Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis

Lee G. D. Fryer, Bethan Jones, Emma J. Duncan, Claire E. Hutchison, Tozen Ozkan, Paul A. Williams, Olivia Alder, Max Nieuwdorp, Anna K. Townley, Arjen R. Mensenkamp, David J. Stephens, Geesje M. Dallinga-Thie, Carol C. Shoulders

J Biol Chem. 2014 Feb 14; 289(7): 4244–4261. Published online 2013 Dec 13. doi: 10.1074/jbc.M113.479980

PMCID:: PMC3924288

Article PDF–1.4M

Select item 73072103.

Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly

David B. Melville, Sean Studer, Randy Schekman

J Biol Chem. 2020 Jun 19; 295(25): 8401–8412. Published online 2020 May 1. doi: 10.1074/jbc.RA120.012964

PMCID:: PMC7307210

Article PDF–3.9M

Select item 61684164.

Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na_v1.5

Zhijie Wang, Gang Yu, Yinan Liu, Shiyong Liu, Meir Aridor, Yuan Huang, Yushuang Hu, Longfei Wang, Sisi Li, Hongbo Xiong, Bo Tang, Xia Li, Chen Cheng, Susmita Chakrabarti, Fan Wang, Qingyu Wu, Sadashiva S. Karnik, Chengqi Xu, Qiuyun Chen, Qing K. Wang

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Nov; 1864(11): 3672–3684. Published online 2018 Sep 6. doi: 10.1016/j.bbadis.2018.09.003

PMCID:: PMC6168416

Article PDF–1.9M

Select item 59775215.

Identification and Characterization of Nine Novel Human Small GTPases Showing Variable Expressions in Liver Cancer Tissues

Hua He, Fangyan Dai, Long Yu, Xingyu She, Yong Zhao, Jianmin Jiang, Xiaosong Chen, Shouyuan Zhao

Gene Expr. 2002; 10(5-6): 231–242. Published online 2018 May 31. doi: 10.3727/000000002783992406

PMCID:: PMC5977521

Article PDF–1.3M

Select item 58530806.

Complex genetic architecture in severe hypobetalipoproteinemia

Linda R. Wang, Adam D. McIntyre, Robert A. Hegele

Lipids Health Dis. 2018; 17: 48. Published online 2018 Mar 14. doi: 10.1186/s12944-018-0680-1

PMCID:: PMC5853080

Article PDF–674K

Select item 47816437.

Secretory protein trafficking and organelle dynamics in living cells.

J Lippincott-Schwartz, T H Roberts, K Hirschberg

Annu Rev Cell Dev Biol. 2000; 16: 557–589. doi: 10.1146/annurev.cellbio.16.1.557

PMCID:: PMC4781643

Article

Select item 48607748.

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair

Patrick Herr, Cecilia Lundin, Bastiaan Evers, Daniel Ebner, Christina Bauerschmidt, Guy Kingham, Timea Palmai-Pallag, Oliver Mortusewicz, Oliver Frings, Erik Sonnhammer, Thomas Helleday

Cell Discov. 2015; 1: 15034. Published online 2015 Dec 1. doi: 10.1038/celldisc.2015.34

PMCID:: PMC4860774

Article PDF–4.1M

Select item 79104599.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Article PDF–3.3M

Select item 913694310.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

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Select item 760600811.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Article PDF–2.5M

Select item 655126612.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Article PDF–3.4M

Select item 673723013.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant

Ana M. Matos, Francisco R. Pinto, Patrícia Barros, Margarida D. Amaral, Rainer Pepperkok, Paulo Matos

J Biol Chem. 2019 Sep 6; 294(36): 13396–13410. Published online 2019 Jul 19. doi: 10.1074/jbc.RA119.008738

PMCID:: PMC6737230

Article PDF–2.6M

Select item 903755414.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Article PDF–4.1M

Select item 1064152415.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Article PDF–3.8M

Select item 790504016.

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer

Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li

Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502

PMCID:: PMC7905040

Article PDF–3.2M

Select item 943393817.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Article PDF–9.3M

Select item 752370618.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Article PDF–2.3M

Select item 318838819.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Article PDF–932K

Select item 917141120.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Article PDF–1.9M

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