PMC Links for Gene (Select 50850) - PMC

Links from Gene

Items: 1 to 20 of 33

<< First< Prev

Page of 2

Select item 109455791.

14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention

Qiuling Liu, Hua Yang, Jianxian Luo, Cheng Peng, Ke Wang, Guowei Zhang, Hongsheng Lin, Zhisheng Ji

eLife. 2024; 12: RP90184. Published online 2024 Jan 17. doi: 10.7554/eLife.90184

PMCID:: PMC10945579

Article PDF–23M

Select item 101129052.

Spastin is an essential regulator of male meiosis, acrosome formation, manchette structure and nuclear integrity

Samuel R. Cheers, Anne E. O'Connor, Travis K. Johnson, D. Jo Merriner, Moira K. O'Bryan, Jessica E. M. Dunleavy

Development. 2023 Mar 15; 150(6): dev201183. Published online 2023 Mar 30. doi: 10.1242/dev.201183

PMCID:: PMC10112905

Article

Select item 74859863.

Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits

André T. Lopes, Torben J. Hausrat, Frank F. Heisler, Kira V. Gromova, Franco L. Lombino, Timo Fischer, Laura Ruschkies, Petra Breiden, Edda Thies, Irm Hermans-Borgmeyer, Michaela Schweizer, Jürgen R. Schwarz, Christian Lohr, Matthias Kneussel

PLoS Biol. 2020 Aug; 18(8): e3000820. Published online 2020 Aug 31. doi: 10.1371/journal.pbio.3000820

PMCID:: PMC7485986

Article PDF–5.0M

Select item 61770014.

Functional differences of short and long isoforms of spastin harboring missense mutation

Clément Plaud, Vandana Joshi, Natallie Kajevu, Christian Poüs, Patrick A. Curmi, Andrea Burgo

Dis Model Mech. 2018 Sep 1; 11(9): dmm033704. Published online 2018 Sep 10. doi: 10.1242/dmm.033704

PMCID:: PMC6177001

Article

Select item 54125675.

Defects in ER–endosome contacts impact lysosome function in hereditary spastic paraplegia

Rachel Allison, James R. Edgar, Guy Pearson, Tania Rizo, Timothy Newton, Sven Günther, Fiamma Berner, Jennifer Hague, James W. Connell, Jürgen Winkler, Jennifer Lippincott-Schwartz, Christian Beetz, Beate Winner, Evan Reid

J Cell Biol. 2017 May 1; 216(5): 1337–1355. doi: 10.1083/jcb.201609033

PMCID:: PMC5412567

Article PDF–4.0M

Select item 48097166.

Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin

James W. Connell, Rachel Allison, Evan Reid

PLoS One. 2016; 11(3): e0152413. Published online 2016 Mar 28. doi: 10.1371/journal.pone.0152413

PMCID:: PMC4809716

Article PDF–2.1M

Select item 35293407.

Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice

Coralie Fassier, Anne Tarrade, Leticia Peris, Sabrina Courageot, Philippe Mailly, Cécile Dalard, Stéphanie Delga, Natacha Roblot, Julien Lefèvre, Didier Job, Jamilé Hazan, Patrick A. Curmi, Judith Melki

Dis Model Mech. 2013 Jan; 6(1): 72–83. Published online 2012 Jul 5. doi: 10.1242/dmm.008946

PMCID:: PMC3529340

Article

Select item 76523968.

Spastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation

Francesca Sardina, Alessandra Pisciottani, Manuela Ferrara, Davide Valente, Marialuisa Casella, Marco Crescenzi, Angelo Peschiaroli, Carlo Casali, Silvia Soddu, Andrew J Grierson, Cinzia Rinaldo

Life Sci Alliance. 2020 Dec; 3(12): e202000799. Published online 2020 Oct 26. doi: 10.26508/lsa.202000799

PMCID:: PMC7652396

Article PDF–2.4M

Select item 71840299.

Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis

Nimesha Tadepalle, Lennart Robers, Matteo Veronese, Peter Zentis, Felix Babatz, Susanne Brodesser, Anja V Gruszczyk, Astrid Schauss, Stefan Höning, Elena I Rugarli

Life Sci Alliance. 2020 Jun; 3(6): e202000715. Published online 2020 Apr 22. doi: 10.26508/lsa.202000715

PMCID:: PMC7184029

Article PDF–3.5M

Select item 229140010.

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

Wenqian Yu, Liang Qiang, Joanna M. Solowska, Arzu Karabay, Sirin Korulu, Peter W. Baas

Mol Biol Cell. 2008 Apr; 19(4): 1485–1498. doi: 10.1091/mbc.E07-09-0878

PMCID:: PMC2291400

Article PDF–2.0M

Select item 916945711.

Modeling gain-of-function and loss-of-function components of SPAST-based hereditary spastic paraplegia using transgenic mice

Emanuela Piermarini, Seyma Akarsu, Theresa Connors, Matthias Kneussel, Michael A Lane, Gerardo Morfini, Arzu Karabay, Peter W Baas, Liang Qiang

Hum Mol Genet. 2022 Jun 1; 31(11): 1844–1859. Published online 2021 Dec 22. doi: 10.1093/hmg/ddab367

PMCID:: PMC9169457

Article PDF–2.0M

Select item 513338912.

Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination

Monika S. Brill, Tatjana Kleele, Laura Ruschkies, Mengzhe Wang, Natalia A. Marahori, Miriam S. Reuter, Torben J. Hausrat, Emily Weigand, Matthew Fisher, Andrea Ahles, Stefan Engelhardt, Derron L. Bishop, Matthias Kneussel, Thomas Misgeld

Neuron. 2016 Nov 23; 92(4): 845–856. doi: 10.1016/j.neuron.2016.09.049

PMCID:: PMC5133389

Article

Select item 383131213.

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

Hans Zempel, Julia Luedtke, Yatender Kumar, Jacek Biernat, Hana Dawson, Eckhard Mandelkow, Eva-Maria Mandelkow

EMBO J. 2013 Nov 13; 32(22): 2920–2937. Published online 2013 Sep 24. doi: 10.1038/emboj.2013.207

PMCID:: PMC3831312

Article PDF–4.6M

Select item 627688814.

Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport

Maria M Magiera, Satish Bodakuntla, Jakub Žiak, Sabrina Lacomme, Patricia Marques Sousa, Sophie Leboucher, Torben J Hausrat, Christophe Bosc, Annie Andrieux, Matthias Kneussel, Marc Landry, André Calas, Martin Balastik, Carsten Janke

EMBO J. 2018 Dec 3; 37(23): e100440. Published online 2018 Nov 12. doi: 10.15252/embj.2018100440

PMCID:: PMC6276888

Article PDF–2.6M

Select item 288635615.

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

Benjamin Lacroix, Juliette van Dijk, Nicholas D. Gold, Julien Guizetti, Gudrun Aldrian-Herrada, Krzysztof Rogowski, Daniel W. Gerlich, Carsten Janke

J Cell Biol. 2010 Jun 14; 189(6): 945–954. doi: 10.1083/jcb.201001024

PMCID:: PMC2886356

Article PDF–6.5M

Select item 428914516.

Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration

Tae-Yeon Eom, Amelia Stanco, Jiami Guo, Gary Wilkins, Danielle Deslauriers, Jessica Yan, Chase Monckton, Josh Blair, Eesim Oon, Abby Perez, Eduardo Salas, Adrianna Oh, Vladimir Ghukasyan, William D. Snider, John L. R. Rubenstein, E. S. Anton

Dev Cell. Author manuscript; available in PMC 2015 Dec 22.

Published in final edited form as: Dev Cell. 2014 Dec 22; 31(6): 677–689. doi: 10.1016/j.devcel.2014.11.022

PMCID:: PMC4289145

Article PDF–2.9M

Select item 741599117.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Article PDF–2.0M

Select item 396495518.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Article PDF–5.7M

Select item 831323919.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 18788520.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Article PDF–287K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 33

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity