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Select item 106143801.

Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress

Yan Peng, Rongmei Qu, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Shutong Wu, Wenqing Liu, Jinhui Zhu, Junxin Chen, Xiaoqing Li, Jingxing Dai, Jun Ouyang

Cell Commun Signal. 2023; 21: 308. Published online 2023 Oct 30. doi: 10.1186/s12964-022-01027-7

PMCID:: PMC10614380

Abstract Article PDF–12M

Select item 93543522.

The clinical significance of integrin subunit alpha V in cancers: from small cell lung carcinoma to pan-cancer

Yu-Lu Tang, Guo-Sheng Li, Dong-Ming Li, Deng Tang, Jie-Zhuang Huang, Hao Feng, Rong-Quan He, Zhi-Guang Huang, Yi-Wu Dang, Jin-Liang Kong, Ting-Qing Gan, Hua-Fu Zhou, Jing-Jing Zeng, Gang Chen

BMC Pulm Med. 2022; 22: 300. Published online 2022 Aug 4. doi: 10.1186/s12890-022-02095-8

PMCID:: PMC9354352

Abstract Article PDF–6.6M

Select item 92099543.

Integrin αV Mediates the Effects of Irisin on Human Mature Adipocytes

Tingting Fu, Chuanzhi Li, Zhongwei Sun, Bing Yan, Yanlin Wu, Zhongxian Huang, Xiao Yin

Obes Facts. 2022 May; 15(3): 442–450. Published online 2022 Mar 23. doi: 10.1159/000523871

PMCID:: PMC9209954

Abstract Article PDF–634K

Select item 82358154.

Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression

Marius Kemper, Alina Schiecke, Hanna Maar, Sergey Nikulin, Andrey Poloznikov, Vladimir Galatenko, Michael Tachezy, Florian Gebauer, Tobias Lange, Kristoffer Riecken, Alexander Tonevitsky, Achim Aigner, Jakob Izbicki, Udo Schumacher, Daniel Wicklein

J Exp Clin Cancer Res. 2021; 40: 214. Published online 2021 Jun 26. doi: 10.1186/s13046-021-01946-2

PMCID:: PMC8235815

Abstract Article PDF–4.3M

Select item 82214655.

SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19

Danielle Nader, Nicola Fletcher, Gerard F. Curley, Steven W. Kerrigan

PLoS One. 2021; 16(6): e0253347. Published online 2021 Jun 23. doi: 10.1371/journal.pone.0253347

PMCID:: PMC8221465

Abstract Article PDF–1.9M

Select item 66399316.

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Chiara Ciardiello, Alessandra Leone, Paola Lanuti, Maria S. Roca, Tania Moccia, Valentina R. Minciacchi, Michele Minopoli, Vincenzo Gigantino, Rossella De Cecio, Massimo Rippa, Lucia Petti, Francesca Capone, Carlo Vitagliano, Maria R. Milone, Biagio Pucci, Rita Lombardi, Federica Iannelli, Elena Di Gennaro, Francesca Bruzzese, Marco Marchisio, Maria V. Carriero, Dolores Di Vizio, Alfredo Budillon

J Exp Clin Cancer Res. 2019; 38: 317. Published online 2019 Jul 18. doi: 10.1186/s13046-019-1317-6

PMCID:: PMC6639931

Abstract Article PDF–7.2M

Select item 65996577.

LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription

Chun Lan Kang, Bing Qi, Qian Qian Cai, Li Sheng Fu, Ying Yang, Chang Tang, Ping Zhu, Qi Wen Chen, Jing Pan, Mei Hua Chen, Xing Zhong Wu

Theranostics. 2019; 9(15): 4421–4436. Published online 2019 Jun 9. doi: 10.7150/thno.32854

PMCID:: PMC6599657

Abstract Article PDF–4.1M

Select item 65988818.

Lack of association between integrin α_vβ₃ gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China

Xiao-Ping Chen, Hai-Rong Xiong, Ni Zhu, Qing-Zhou Chen, Hui Wang, Chao-Jie Zhong, Mei-Rong Wang, Shuang Lu, Fan Luo, Wei Hou

Virol Sin. 2017 Feb; 32(1): 73–79. Published online 2017 Feb 9. doi: 10.1007/s12250-016-3888-0

PMCID:: PMC6598881

Abstract Article PDF–458K

Select item 55416739.

Abituzumab Targeting of αV-class Integrins Inhibits Prostate Cancer Progression

Yuan Jiang, Jinlu Dai, Zhi Yao, Greg Shelley, Evan T. Keller

Mol Cancer Res. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Mol Cancer Res. 2017 Jul; 15(7): 875–883. Published online 2017 Mar 17. doi: 10.1158/1541-7786.MCR-16-0447

PMCID:: PMC5541673

Abstract Article PDF–1.9M

Select item 514401010.

A proteolytic modification of AIM promotes its renal excretion

Tomoko Yamazaki, Ryoichi Sugisawa, Emiri Hiramoto, Ryosuke Takai, Ayaka Matsumoto, Yoshie Senda, Katsuhiko Nakashima, Peter S. Nelson, Jared M. Lucas, Andrew Morgan, Zhenghua Li, Ken-ichi Yamamura, Satoko Arai, Toru Miyazaki

Sci Rep. 2016; 6: 38762. Published online 2016 Dec 8. doi: 10.1038/srep38762

PMCID:: PMC5144010

Abstract Article PDF–1.3M

Select item 498461611.

Role for the αV Integrin Subunit in Varicella-Zoster Virus-Mediated Fusion and Infection

Edward Yang, Ann M. Arvin, Stefan L. Oliver

J Virol. 2016 Aug 15; 90(16): 7567–7578. Prepublished online 2016 Jun 8. Published online 2016 Jul 27. doi: 10.1128/JVI.00792-16

PMCID:: PMC4984616

Abstract Article PDF–2.5M

Select item 492476812.

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

Michael Weller, Louis Burt Nabors, Thierry Gorlia, Henning Leske, Elisabeth Rushing, Pierre Bady, Christine Hicking, James Perry, Yong-Kil Hong, Patrick Roth, Wolfgang Wick, Simon L. Goodman, Monika E. Hegi, Martin Picard, Holger Moch, Josef Straub, Roger Stupp

Oncotarget. 2016 Mar 22; 7(12): 15018–15032. Published online 2016 Feb 22. doi: 10.18632/oncotarget.7588

PMCID:: PMC4924768

Abstract Article PDF–7.9M

Select item 438151013.

Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

Yihao Li, Yvette Drabsch, Philippe Pujuguet, Jiang Ren, Theo van Laar, Long Zhang, Hans van Dam, Philippe Clément-Lacroix, Peter ten Dijke

Breast Cancer Res. 2015; 17(1): 28. Published online 2015 Feb 25. doi: 10.1186/s13058-015-0537-8

PMCID:: PMC4381510

Abstract Article PDF–2.5M

Select item 428151214.

Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo

Liangru W. Contois, Abebe Akalu, Jennifer M. Caron, Eric Tweedie, Alexandra Cretu, Terry Henderson, Lucy Liaw, Robert Friesel, Calvin Vary, Peter C. Brooks

Angiogenesis. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Angiogenesis. 2015 Jan; 18(1): 31–46. Published online 2014 Sep 24. doi: 10.1007/s10456-014-9445-2

PMCID:: PMC4281512

Abstract Article PDF–1.9M

Select item 410188515.

Regulation of Ionizing Radiation-Induced Adhesion of Breast Cancer Cells to Fibronectin by Alpha5beta1 Integrin

Shin Hee Lee, Huiwen Cheng, Ye Yuan, Shiyong Wu

Radiat Res. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Radiat Res. 2014 Jun; 181(6): 650–658. Published online 2014 May 1. doi: 10.1667/RR13543.1

PMCID:: PMC4101885

Abstract Article PDF–2.9M

Select item 372337716.

Activated αvβ3 Integrin Regulates αvβ5 Integrin–Mediated Phagocytosis in Trabecular Meshwork Cells

Debjani Gagen, Mark S. Filla, Ross Clark, Paloma Liton, Donna M. Peters

Invest Ophthalmol Vis Sci. 2013 Jul; 54(7): 5000–5011. Published online 2013 Jul 24. doi: 10.1167/iovs.13-12084

PMCID:: PMC3723377

Abstract Article PDF–1.2M

Select item 366059317.

Glioma Initiating Cells Form a Differentiation Niche Via the Induction of Extracellular Matrices and Integrin αV

Akiko Niibori-Nambu, Uichi Midorikawa, Souhei Mizuguchi, Takuichiro Hide, Minako Nagai, Yoshihiro Komohara, Megumi Nagayama, Mio Hirayama, Daiki Kobayashi, Nobuyuki Tsubota, Tatsuya Takezaki, Keishi Makino, Hideo Nakamura, Motohiro Takeya, Junichi Kuratsu, Norie Araki

PLoS One. 2013; 8(5): e59558. Published online 2013 May 21. doi: 10.1371/journal.pone.0059558

PMCID:: PMC3660593

Abstract Article PDF–4.9M

Select item 349533118.

α_Vβ₃ Integrin Crystal Structures and their Functional Implications

Xianchi Dong, Li-Zhi Mi, Jianghai Zhu, Wei Wang, Ping Hu, Bing-Hao Luo, Timothy A. Springer

Biochemistry. Author manuscript; available in PMC 2013 Nov 6.

Published in final edited form as: Biochemistry. 2012 Nov 6; 51(44): 8814–8828. Published online 2012 Oct 29. doi: 10.1021/bi300734n

PMCID:: PMC3495331

Abstract Article PDF–7.8M

Select item 337483919.

αV Integrin Induces Multicellular Radioresistance in Human Nasopharyngeal Carcinoma via Activating SAPK/JNK Pathway

Juanjuan Ou, Wei Luan, Jia Deng, Rina Sa, Houjie Liang

PLoS One. 2012; 7(6): e38737. Published online 2012 Jun 13. doi: 10.1371/journal.pone.0038737

PMCID:: PMC3374839

Abstract Article PDF–4.2M

Select item 332386620.

Combined QM/MM Study of Thyroid and Steroid Hormone Analogue Interactions with αvβ3 Integrin

Marek Freindorf, Thomas R. Furlani, Jing Kong, Vivian Cody, Faith B. Davis, Paul J. Davis

J Biomed Biotechnol. 2012; 2012: 959057. Published online 2012 Apr 2. doi: 10.1155/2012/959057

PMCID:: PMC3323866

Abstract Article PDF–6.6M

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