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Select item 99536311.

Genetic Variants of ISL1 Gene Promoter Identified from Congenital Tetralogy of Fallot Patients Alter Cellular Function Forming Disease Basis

Xiu-Yun Yin, Huan-Xin Chen, Zhuo Chen, Qin Yang, Jun Han, Guo-Wei He

Biomolecules. 2023 Feb; 13(2): 358. Published online 2023 Feb 13. doi: 10.3390/biom13020358

PMCID:: PMC9953631

Article PDF–1.9M

Select item 85783902.

ISL1 promotes enzalutamide resistance in castration-resistant prostate cancer (CRPC) through epithelial to mesenchymal transition (EMT)

Jae Duck Choi, Tae Jin Kim, Byong Chang Jeong, Hwang Gyun Jeon, Seong Soo Jeon, Min Yong Kang, Seon Yong Yeom, Seong Il Seo

Sci Rep. 2021; 11: 21984. Published online 2021 Nov 9. doi: 10.1038/s41598-021-01003-0

PMCID:: PMC8578390

Article PDF–1.4M

Select item 82061283.

ISL1 promoted tumorigenesis and EMT via Aurora kinase A-induced activation of PI3K/AKT signaling pathway in neuroblastoma

Mengzhen Li, Chengtao Sun, Xiaoyun Bu, Yi Que, Lian Zhang, Yu Zhang, Li Zhang, Suying Lu, Junting Huang, Jia Zhu, Juan Wang, Feifei Sun, Yizhuo Zhang

Cell Death Dis. 2021 Jun; 12(6): 620. Published online 2021 Jun 15. doi: 10.1038/s41419-021-03894-3

PMCID:: PMC8206128

Article PDF–7.0M

Select item 81234494.

Overexpression of Isl1 under the Pax2 Promoter, Leads to Impaired Sound Processing and Increased Inhibition in the Inferior Colliculus

Tetyana Chumak, Diana Tothova, Iva Filova, Zbynek Bures, Jiri Popelar, Gabriela Pavlinkova, Josef Syka

Int J Mol Sci. 2021 May; 22(9): 4507. Published online 2021 Apr 26. doi: 10.3390/ijms22094507

PMCID:: PMC8123449

Article PDF–3.5M

Select item 79579945.

Association of ISL1 polymorphisms and eosinophilic levels among otitis media patients

Abhishek Kondyarpu, Chinmay Sundar Ray, Khirod Chandra Panda, Narayan Chandra Biswal, Puppala Venkat Ramchander

J Clin Lab Anal. 2021 Mar; 35(3): e23702. Published online 2021 Jan 21. doi: 10.1002/jcla.23702

PMCID:: PMC7957994

Article PDF–535K

Select item 69598846.

Correlations between ISL1 rs1017 polymorphism and congenital heart disease risk: A PRISMA-compliant meta-analysis

Zhaohong Ding, Wenke Yang, Kang Yi, Yunhan Ding, Dan Zhou, Xiaodong Xie, Tao You

Medicine (Baltimore) 2020 Jan; 99(2): e18715. Published online 2020 Jan 10. doi: 10.1097/MD.0000000000018715

PMCID:: PMC6959884

Article PDF–493K

Select item 61927547.

ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple-negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai

Int J Mol Med. 2018 Nov; 42(5): 2343–2352. Published online 2018 Aug 27. doi: 10.3892/ijmm.2018.3842

PMCID:: PMC6192754

Article PDF–1.4M

Select item 60353408.

Human ISL1⁺ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction

Kylie S. Foo, Miia L. Lehtinen, Chuen Yan Leung, Xiaojun Lian, Jiejia Xu, Wendy Keung, Lin Geng, Terje R.S. Kolstad, Sebastian Thams, Andy On-tik Wong, Nicodemus Wong, Kristine Bylund, Chikai Zhou, Xiaobing He, Shao-Bo Jin, Jonathan Clarke, Urban Lendahl, Ronald A. Li, William E. Louch, Kenneth R. Chien

Mol Ther. 2018 Jul 5; 26(7): 1644–1659. Published online 2018 Feb 17. doi: 10.1016/j.ymthe.2018.02.012

Correction in:: Mol Ther. 2021 Jan 6; 29(1): 409.

PMCID:: PMC6035340

Article PDF–8.8M

Select item 43574229.

Genome-wide Association Study and Meta-Analysis Identify ISL1 as Genome-wide Significant Susceptibility Gene for Bladder Exstrophy

Markus Draaken, Michael Knapp, Tracie Pennimpede, Johanna M. Schmidt, Anne-Karolin Ebert, Wolfgang Rösch, Raimund Stein, Boris Utsch, Karin Hirsch, Thomas M. Boemers, Elisabeth Mangold, Stefanie Heilmann, Kerstin U. Ludwig, Ekkehart Jenetzky, Nadine Zwink, Susanne Moebus, Bernhard G. Herrmann, Manuel Mattheisen, Markus M. Nöthen, Michael Ludwig, Heiko Reutter

PLoS Genet. 2015 Mar; 11(3): e1005024. Published online 2015 Mar 12. doi: 10.1371/journal.pgen.1005024

PMCID:: PMC4357422

Article PDF–6.7M

Select item 339600010.

ISL1 Common Variant rs1017 Is Not Associated with Susceptibility to Congenital Heart Disease in a Chinese Population

Lei Xue, Xiaowei Wang, Jing Xu, Xiaohan Xu, Xiang Liu, Zhibin Hu, Hongbing Shen, Yijiang Chen

Genet Test Mol Biomarkers. 2012 Jul; 16(7): 679–683. doi: 10.1089/gtmb.2011.0249

PMCID:: PMC3396000

Article PDF–151K

Select item 1067965311.

The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5

Bonnie E.J. Maven, Casey A. Gifford, Melanie Weilert, Barbara Gonzalez-Teran, Ruth Hüttenhain, Angelo Pelonero, Kathryn N. Ivey, Kaitlen Samse-Knapp, Wesley Kwong, David Gordon, Michael McGregor, Tomohiro Nishino, Eyuche Okorie, Sage Rossman, Mauro W. Costa, Nevan J. Krogan, Julia Zeitlinger, Deepak Srivastava

Stem Cell Reports. 2023 Nov 14; 18(11): 2138–2153. Published online 2023 Oct 19. doi: 10.1016/j.stemcr.2023.09.014

PMCID:: PMC10679653

Article PDF–5.0M

Select item 810619212.

Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer

Qiong Shi, Xiaomei Ni, Ming Lei, Quansong Xia, Yan Dong, Qiao Zhang, Weiping Wang

Mol Med. 2021; 27: 47. Published online 2021 May 7. doi: 10.1186/s10020-021-00302-6

PMCID:: PMC8106192

Article PDF–3.7M

Select item 796888613.

Insulin gene enhancer protein 1 mediates glycolysis and tumorigenesis of gastric cancer through regulating glucose transporter 4

Ting Guo, Yan‐Hua Bai, Xiao‐Jing Cheng, Hai‐Bo Han, Hong Du, Ying Hu, Shu‐Qin Jia, Xiao‐Fang Xing, Jia‐Fu Ji

Cancer Commun (Lond) 2021 Mar; 41(3): 258–272. Published online 2021 Feb 11. doi: 10.1002/cac2.12141

PMCID:: PMC7968886

Article PDF–2.6M

Select item 789389114.

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

Emilia Solomon, Katie Davis-Anderson, Blake Hovde, Sofiya Micheva-Viteva, Jennifer Foster Harris, Scott Twary, Rashi Iyer

BMC Mol Cell Biol. 2021; 22: 13. Published online 2021 Feb 18. doi: 10.1186/s12860-021-00343-z

PMCID:: PMC7893891

Article PDF–1.5M

Select item 640140515.

Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN

Qitong Zhang, Qingquan Zhang, Xue Jiang, Youqiong Ye, Huimin Liao, Fugui Zhu, Jie Yan, Lina Luo, Li Tian, Cizhong Jiang, Yihan Chen, Xingqun Liang, Yunfu Sun

Theranostics. 2019; 9(4): 986–1000. Published online 2019 Jan 30. doi: 10.7150/thno.30199

PMCID:: PMC6401405

Article PDF–2.9M

Select item 582830916.

ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model

Qiuling Xiang, Yan Liao, Hua Chao, Weijun Huang, Jia Liu, Haixuan Chen, Dongxi Hong, Zhengwei Zou, Andy Peng Xiang, Weiqiang Li

Stem Cell Res Ther. 2018; 9: 51. Published online 2018 Feb 26. doi: 10.1186/s13287-018-0803-7

PMCID:: PMC5828309

Article PDF–3.0M

Select item 577015817.

Revised roles of ISL1 in a hES cell-based model of human heart chamber specification

Roberto Quaranta, Jakob Fell, Frank Rühle, Jyoti Rao, Ilaria Piccini, Marcos J Araúzo-Bravo, Arie O Verkerk, Monika Stoll, Boris Greber

eLife. 2018; 7: e31706. Published online 2018 Jan 16. doi: 10.7554/eLife.31706

PMCID:: PMC5770158

Article PDF–4.5M

Select item 455800318.

Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer

Mark O. Kitchen, Richard T. Bryan, Kim E. Haworth, Richard D. Emes, Christopher Luscombe, Lyndon Gommersall, K. K. Cheng, Maurice P. Zeegers, Nicholas D. James, Adam J. Devall, Anthony A. Fryer, William E. Farrell

PLoS One. 2015; 10(9): e0137003. Published online 2015 Sep 2. doi: 10.1371/journal.pone.0137003

PMCID:: PMC4558003

Article PDF–620K

Select item 379023419.

Driving vascular endothelial cell fate of human multipotent Isl1⁺ heart progenitors with VEGF modified mRNA

Kathy O Lui, Lior Zangi, Eduardo A Silva, Lei Bu, Makoto Sahara, Ronald A Li, David J Mooney, Kenneth R Chien

Cell Res. 2013 Oct; 23(10): 1172–1186. Published online 2013 Sep 10. doi: 10.1038/cr.2013.112

PMCID:: PMC3790234

Article PDF–2.7M

Select item 327516220.

A Distal Modular Enhancer Complex Acts to Control Pituitary- and Nervous System-Specific Expression of the LHX3 Regulatory Gene

Rachel D. Mullen, Soyoung Park, Simon J. Rhodes

Mol Endocrinol. 2012 Feb; 26(2): 308–319. Published online 2011 Dec 22. doi: 10.1210/me.2011-1252

PMCID:: PMC3275162

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