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Items: 1 to 20 of 23

1.
TIN2 deficiency leads to ALT-associated phenotypes and differentiation defects in embryonic stem cells
Shanshan Yin, Fangyingnan Zhang, Song Lin, Wei Chen, Kai Weng, Dan Liu, Chuanle Wang, Zibin He, Yuxi Chen, Wenbin Ma, Junjiu Huang, Yan Huang, Zhou Songyang
Stem Cell Reports. 2022 May 10; 17(5): 1183–1197. Published online 2022 Apr 7. doi: 10.1016/j.stemcr.2022.03.005
PMCID:
PMC9120858
ArticlePDF–2.5M
2.
TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA
Parminder Kaur, Ryan Barnes, Hai Pan, Ariana C Detwiler, Ming Liu, Chelsea Mahn, Jonathan Hall, Zach Messenger, Changjiang You, Jacob Piehler, Robert C Smart, Robert Riehn, Patricia L Opresko, Hong Wang
Nucleic Acids Res. 2021 Dec 16; 49(22): 13000–13018. Published online 2021 Dec 9. doi: 10.1093/nar/gkab1142
PMCID:
PMC8682769
ArticlePDF–6.2M
3.
Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice
K Hartmann, A Illing, F Leithäuser, A Baisantry, L Quintanilla-Martinez, K L Rudolph
Leukemia. 2016 Mar; 30(3): 749–753. Prepublished online 2015 Jul 2. Published online 2015 Jul 31. doi: 10.1038/leu.2015.173
Correction in:
Leukemia. 2017; 31(12): 2853.
PMCID:
PMC4777776
ArticlePDF–463K
4.
A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice
David Frescas, Titia de Lange
Genes Dev. 2014 Jan 15; 28(2): 153–166. doi: 10.1101/gad.233395.113
PMCID:
PMC3909789
ArticlePDF–2.4M
5.
Telomere-Associated Protein TIN2 Is Essential for Early Embryonic Development through a Telomerase-Independent Pathway
Y. Jeffrey Chiang, Sahn-Ho Kim, Lino Tessarollo, Judith Campisi, Richard J. Hodes
Mol Cell Biol. 2004 Aug; 24(15): 6631–6634. doi: 10.1128/MCB.24.15.6631-6634.2004
PMCID:
PMC444850
ArticlePDF–123K
6.
Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex
Chunyi Hu, Rekha Rai, Chenhui Huang, Cayla Broton, Juanjuan Long, Ying Xu, Jing Xue, Ming Lei, Sandy Chang, Yong Chen
Cell Res. 2017 Dec; 27(12): 1485–1502. Published online 2017 Nov 21. doi: 10.1038/cr.2017.144
PMCID:
PMC5717407
ArticlePDF–18M
7.
Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection
David Frescas, Titia de Lange
J Biol Chem. 2014 Aug 29; 289(35): 24180–24187. Published online 2014 Jul 23. doi: 10.1074/jbc.M114.592592
PMCID:
PMC4148849
ArticlePDF–2.5M
8.
The C-Terminal Extension Unique to the Long Isoform of the Shelterin Component TIN2 Enhances Its Interaction with TRF2 in a Phosphorylation- and Dyskeratosis Congenita Cluster-Dependent Fashion
Nya D. Nelson, Lois M. Dodson, Laura Escudero, Ann T. Sukumar, Christopher L. Williams, Ivana Mihalek, Alessandro Baldan, Duncan M. Baird, Alison A. Bertuch
Mol Cell Biol. 2018 Jun 15; 38(12): e00025-18. Prepublished online 2018 Mar 26. Published online 2018 May 29. doi: 10.1128/MCB.00025-18
PMCID:
PMC5974431
ArticlePDF–2.2M
9.
TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1
David Frescas, Titia de Lange
Mol Cell Biol. 2014 Apr; 34(7): 1349–1362. doi: 10.1128/MCB.01052-13
PMCID:
PMC3993560
ArticlePDF–5.2M
10.
TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling
Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange
Genes Dev. 2014 Nov 15; 28(22): 2477–2491. doi: 10.1101/gad.251611.114
PMCID:
PMC4233241
ArticlePDF–1.6M
11.
Telomere protection by TPP1/POT1 requires tethering to TIN2
Kaori K. Takai, Tatsuya Kibe, Jill R. Donigian, David Frescas, Titia de Lange
Mol Cell. Author manuscript; available in PMC 2012 Nov 18.
Published in final edited form as: Mol Cell. 2011 Nov 18; 44(4): 647–659. doi: 10.1016/j.molcel.2011.08.043
Correction in:
Mol Cell. 2017 Jul 6; 67(1): 162.
PMCID:
PMC3222871
ArticlePDF–4.7M
12.
The differential spatiotemporal expression pattern of shelterin genes throughout lifespan
Kay-Dietrich Wagner, Yilin Ying, Waiian Leong, Jie Jiang, Xuefei Hu, Yi Chen, Jean-François Michiels, Yiming Lu, Eric Gilson, Nicole Wagner, Jing Ye
Aging (Albany NY) 2017 Apr; 9(4): 1219–1228. Published online 2017 Apr 17. doi: 10.18632/aging.101223
PMCID:
PMC5425123
ArticlePDF–4.4M
13.
Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition
Jing Chen, Collin Melton, Nayoung Suh, Jeong Su Oh, Kathleen Horner, Fang Xie, Claudio Sette, Robert Blelloch, Marco Conti
Genes Dev. 2011 Apr; 25(7): 755–766. doi: 10.1101/gad.2028911
PMCID:
PMC3070937
ArticlePDF–965K
14.
HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment
Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Londoño-Vallejo, Matthias Mann, Frank Buchholz
EMBO J. 2013 Jun 12; 32(12): 1681–1701. Published online 2013 May 17. doi: 10.1038/emboj.2013.105
PMCID:
PMC3680732
ArticlePDF–1.6M
15.
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex
Pauline Antonie Ulmke, M. Sadman Sakib, Peter Ditte, Godwin Sokpor, Cemil Kerimoglu, Linh Pham, Yuanbin Xie, Xiaoyi Mao, Joachim Rosenbusch, Ulrike Teichmann, Huu Phuc Nguyen, Andre Fischer, Gregor Eichele, Jochen F. Staiger, Tran Tuoc
Stem Cell Reports. 2021 Apr 13; 16(4): 968–984. Published online 2021 Apr 1. doi: 10.1016/j.stemcr.2021.03.008
PMCID:
PMC8072132
ArticlePDF–8.1M
16.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
ArticlePDF–1.6M
17.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
ArticlePDF–847K
18.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
ArticlePDF–481K
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
ArticlePDF–3.8M
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
ArticlePDF–3.4M

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