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Select item 105878541.

Targeted ablation of Fn14 receptor improves exercise capacity and inhibits neurogenic muscle atrophy

Meiricris Tomaz da Silva, Aniket S. Joshi, Tatiana E. Koike, Anirban Roy, Kavya Mathukumalli, Danesh H. Sopariwala, Vihang A. Narkar, Ashok Kumar

FASEB J. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: FASEB J. 2022 Dec; 36(12): e22666. doi: 10.1096/fj.202201583R

PMCID:: PMC10587854

Abstract Article PDF–2.5M

Select item 105617652.

Fn14 promotes myoblast fusion during regenerative myogenesis

Meiricris Tomaz da Silva, Aniket S Joshi, Micah B Castillo, Tatiana E Koike, Anirban Roy, Preethi H Gunaratne, Ashok Kumar

Life Sci Alliance. 2023 Dec; 6(12): e202302312. Published online 2023 Oct 9. doi: 10.26508/lsa.202302312

PMCID:: PMC10561765

Abstract Article PDF–5.2M

Select item 93385863.

Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice

Xin-Xin Guan, Hui-Hui Yang, Wen-Jing Zhong, Jia-Xi Duan, Chen-Yu Zhang, Hui-Ling Jiang, Yang Xiang, Yong Zhou, Cha-Xiang Guan

Mol Med. 2022; 28: 85. Published online 2022 Jul 30. doi: 10.1186/s10020-022-00514-4

PMCID:: PMC9338586

Abstract Article PDF–5.9M

Select item 80179334.

Developmental synaptic regulator, TWEAK/Fn14 signaling, is a determinant of synaptic function in models of stroke and neurodegeneration

Dávid Nagy, Katelin A. Ennis, Ru Wei, Susan C. Su, Christopher A. Hinckley, Rong-Fang Gu, Benbo Gao, Ramiro H. Massol, Chris Ehrenfels, Luke Jandreski, Ankur M. Thomas, Ashley Nelson, Stefka Gyoneva, Mihály Hajós, Linda C. Burkly

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2001679118. Published online 2021 Feb 1. doi: 10.1073/pnas.2001679118

PMCID:: PMC8017933

Abstract Article PDF–1.9M

Select item 67281715.

Fn14 participates in neuropathic pain through NF-κB pathway in primary sensory neurons

Li-Na Huang, Yun Zou, Shao-Gen Wu, Hong-Hong Zhang, Qing-Xiang Mao, Jin-Bao Li, Yuan-Xiang Tao

Mol Neurobiol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Mol Neurobiol. 2019 Oct; 56(10): 7085–7096. Published online 2019 Apr 11. doi: 10.1007/s12035-019-1545-y

PMCID:: PMC6728171

Abstract Article PDF–1.2M

Select item 63118486.

Fn14 Deficiency Ameliorates Anti-dsDNA IgG-Induced Glomerular Damage in SCID Mice

Jiawen Wu, Xiaoyun Min, Li Wang, Jie Yang, Ping Wang, Xingyin Liu, Yumin Xia

J Immunol Res. 2018; 2018: 1256379. Published online 2018 Dec 16. doi: 10.1155/2018/1256379

PMCID:: PMC6311848

Abstract Article PDF–5.2M

Select item 60565517.

Fn14 deficiency ameliorates psoriasis-like skin disease in a murine model

L. Peng, Q. Li, H. Wang, J. Wu, C. Li, Y. Liu, J. Liu, L. Xia, Y. Xia

Cell Death Dis. 2018 Aug; 9(8): 801. Published online 2018 Jul 23. doi: 10.1038/s41419-018-0820-6

Correction in:: Cell Death Dis. 2023 Mar; 14(3): 218.

PMCID:: PMC6056551

Abstract Article PDF–2.4M

Select item 59065468.

TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia–Ischemia

Anton Kichev, Ana A. Baburamani, Regina Vontell, Pierre Gressens, Linda Burkly, Claire Thornton, Henrik Hagberg

Front Neurol. 2018; 9: 230. Published online 2018 Apr 12. doi: 10.3389/fneur.2018.00230

PMCID:: PMC5906546

Abstract Article PDF–7.4M

Select item 43294789.

Role of Fn14 in acute alcoholic steatohepatitis in mice

Gamze Karaca, Guanhua Xie, Cynthia Moylan, Marzena Swiderska-Syn, Cynthia D. Guy, Leandi Krüger, Mariana Verdelho Machado, Steve S. Choi, Gregory A. Michelotti, Linda C. Burkly, Anna Mae Diehl

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15; 308(4): G325–G334. Published online 2014 Dec 18. doi: 10.1152/ajpgi.00429.2013

PMCID:: PMC4329478

Abstract Article

Select item 404911310.

The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle

Marjan M. Tajrishi, Shuichi Sato, Jonghyun Shin, Timothy S. Zheng, Linda C. Burkly, Ashok Kumar

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Apr 18.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Apr 18; 446(4): 1219–1224. Published online 2014 Mar 26. doi: 10.1016/j.bbrc.2014.03.084

PMCID:: PMC4049113

Abstract Article PDF–1.1M

Select item 394531011.

The Expression of Fn14 via Mechanical Stress-activated JNK Contributes to Apoptosis Induction in Osteoblasts

Hiroyuki Matsui, Naoto Fukuno, Yoshiaki Kanda, Yusuke Kantoh, Toko Chida, Yuko Nagaura, Osamu Suzuki, Hideki Nishitoh, Kohsuke Takeda, Hidenori Ichijo, Yasuhiro Sawada, Keiichi Sasaki, Takayasu Kobayashi, Shinri Tamura

J Biol Chem. 2014 Mar 7; 289(10): 6438–6450. Published online 2014 Jan 20. doi: 10.1074/jbc.M113.536300

PMCID:: PMC3945310

Abstract Article PDF–2.6M

Select item 359727112.

Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction

Tatyana Novoyatleva, Yves Schymura, Wiebke Janssen, Frederic Strobl, Jakub M. Swiercz, Chinmoy Patra, Guido Posern, Astrid Wietelmann, Timothy S. Zheng, Ralph T. Schermuly, Felix B. Engel

Basic Res Cardiol. 2013; 108(2): 325. Published online 2013 Jan 17. doi: 10.1007/s00395-012-0325-x

PMCID:: PMC3597271

Abstract Article PDF–1.1M

Select item 348337713.

Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis

Yumin Xia, Sean R. Campbell, Anna Broder, Leal Herlitz, Maria Abadi, Ping Wu, Jennifer S. Michaelson, Linda C. Burkly, Chaim Putterman

Clin Immunol. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Clin Immunol. 2012 Nov; 145(2): 108–121. Published online 2012 Aug 20. doi: 10.1016/j.clim.2012.08.008

PMCID:: PMC3483377

Abstract Article PDF–3.2M

Select item 1053146714.

Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia

Bryan I. Ruiz, Xazmin H. Lowman, Ying Yang, Qi Fan, Tianhong Wang, Hongmei Wu, Eric A. Hanse, Mei Kong

Genes (Basel) 2023 Sep; 14(9): 1818. Published online 2023 Sep 19. doi: 10.3390/genes14091818

PMCID:: PMC10531467

Abstract Article PDF–2.6M

Select item 791645015.

Remodeling of Neurotransmission, Chemokine, and PI3K-AKT Signaling Genomic Fabrics in Neuropsychiatric Systemic Lupus Erythematosus

Dumitru Iacobas, Jing Wen, Sanda Iacobas, Noa Schwartz, Chaim Putterman

Genes (Basel) 2021 Feb; 12(2): 251. Published online 2021 Feb 10. doi: 10.3390/genes12020251

PMCID:: PMC7916450

Abstract Article PDF–3.6M

Select item 734942116.

MicroRNA-19a Targets Fibroblast Growth Factor-Inducible Molecule 14 and Prevents Tubular Damage in Septic AKI

Jun Hong, Bang-Chuan Hu, Liang Xu, Yang Zheng, Zi-Qiang Shao, Run Zhang, Xiang-Hong Yang, Ren-Hua Sun, Shi-Jing Mo

Anal Cell Pathol (Amst) 2020; 2020: 2894650. Published online 2020 Jul 1. doi: 10.1155/2020/2894650

PMCID:: PMC7349421

Abstract Article PDF–1.5M

Select item 690466017.

Experimental atopic dermatitis is dependent on the TWEAK/Fn14 signaling pathway

Q. Liu, H. Wang, X. Wang, M. Lu, X. Tan, L. Peng, F. Tan, T. Xiao, S. Xiao, Y. Xia

Clin Exp Immunol. 2020 Jan; 199(1): 56–67. Published online 2019 Sep 17. doi: 10.1111/cei.13373

PMCID:: PMC6904660

Abstract Article PDF–1.4M

Select item 549359518.

TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis

Daniel Sidler, Ping Wu, Rana Herro, Meike Claus, Dennis Wolf, Yuko Kawakami, Toshiaki Kawakami, Linda Burkly, Michael Croft

Nat Commun. 2017; 8: 15395. Published online 2017 May 22. doi: 10.1038/ncomms15395

PMCID:: PMC5493595

Abstract Article PDF–1.9M

Select item 538539619.

Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

Takuhito Sezaki, Yuki Hirata, Teruki Hagiwara, Yuki I Kawamura, Tadashi Okamura, Rieko Takanashi, Kenta Nakano, Miwa Tamura-Nakano, Linda C Burkly, Taeko Dohi

World J Gastroenterol. 2017 Apr 7; 23(13): 2294–2307. Published online 2017 Apr 7. doi: 10.3748/wjg.v23.i13.2294