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Items: 1 to 20 of 103

1.
NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos
Fangnong Lai, Lijia Li, Xiaoyu Hu, Bofeng Liu, Ziqi Zhu, Ling Liu, Qiang Fan, Huabin Tian, Kai Xu, Xukun Lu, Qing Li, Kong Feng, Lijuan Wang, Zili Lin, Hongyu Deng, Jinsong Li, Wei Xie
Cell Res. 2023 Dec; 33(12): 952–966. Published online 2023 Nov 7. doi: 10.1038/s41422-023-00887-z
PMCID:
PMC10709309
ArticlePDF–2.5M
2.
NR5A2 as a potential target for exercise to improve metabolic syndrome
Lingxiu Meng, Fusheng Dong, Junguo Deng
Aging (Albany NY) 2023 Apr 15; 15(7): 2485–2502. Published online 2023 Mar 26. doi: 10.18632/aging.204606
PMCID:
PMC10120892
ArticlePDF–4.4M
3.
LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Noelia García Rodríguez, Irene de Gracia Herrera Gómez, Esther Fuente-Martin, Livia López-Noriega, José Manuel Mellado-Gil, Silvana-Yanina Romero-Zerbo, Mathurin Baquié, Christian Claude Lachaud, Katja Stifter, German Perdomo, Marco Bugliani, Vincenzo De Tata, Domenico Bosco, Geraldine Parnaud, David Pozo, Abdelkrim Hmadcha, Javier P. Florido, Miguel G. Toscano, Peter de Haan, Kristina Schoonjans, Luis Sánchez Palazón, Piero Marchetti, Reinhold Schirmbeck, Alejandro Martín-Montalvo, Paolo Meda, Bernat Soria, Francisco-Javier Bermúdez-Silva, Luc St-Onge, Benoit R. Gauthier
Nat Commun. 2018; 9: 1488. Published online 2018 Apr 16. doi: 10.1038/s41467-018-03943-0
PMCID:
PMC5902555
ArticlePDF–5.6M
4.
Identification of transcription factors and single nucleotide polymorphisms of Lrh1 and its homologous genes in Lrh1-knockout pancreas of mice
Maochun Tang, Li Cheng, Rongrong Jia, Lei Qiu, Hua Liu, Shu Zhou, Xiuying Ma, Guoyong Hu, Xingpeng Wang, Yan Zhao
BMC Med Genet. 2014; 15: 43. Published online 2014 Apr 15. doi: 10.1186/1471-2350-15-43
PMCID:
PMC3996308
ArticlePDF–693K
5.
Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation
Guido von Figura, John P Morris, IV, Christopher V E Wright, Matthias Hebrok
Gut. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Gut. 2014 Apr; 63(4): 656–664. Published online 2013 May 3. doi: 10.1136/gutjnl-2012-304287
PMCID:
PMC3883808
ArticlePDF–4.8M
6.
LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function
Sam R. Holmstrom, Tye Deering, Galvin H. Swift, Frank J. Poelwijk, David J. Mangelsdorf, Steven A. Kliewer, Raymond J. MacDonald
Genes Dev. 2011 Aug 15; 25(16): 1674–1679. doi: 10.1101/gad.16860911
PMCID:
PMC3165932
ArticlePDF–1018K
7.
Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene Expression
Ryan T Wagner, Xueping Xu, Fei Yi, Bradley J Merrill, Austin J Cooney
Stem Cells. 2010 Oct; 28(10): 1794–1804. Published online 2010 Oct 23. doi: 10.1002/stem.502
PMCID:
PMC2996860
ArticlePDF–932K
8.
α1-Fetoprotein Transcription Factor (FTF)/Liver Receptor Homolog-1 (LRH-1) Is an Essential Lipogenic Regulator
Zhumei Xu, Lingli Ouyang, Antonio del Castillo-Olivares, William M. Pandak, Gregorio Gil
Biochim Biophys Acta. Author manuscript; available in PMC 2011 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Apr; 1801(4): 473–479. Published online 2009 Dec 28. doi: 10.1016/j.bbalip.2009.12.009
PMCID:
PMC2826527
ArticlePDF–276K
9.
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
Matthias Mueller, Igor Cima, Mario Noti, Andrea Fuhrer, Sabine Jakob, Laurent Dubuquoy, Kristina Schoonjans, Thomas Brunner
J Exp Med. 2006 Sep 4; 203(9): 2057–2062. doi: 10.1084/jem.20060357
PMCID:
PMC2118403
ArticlePDF–549K
10.
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease
Agnes Coste, Laurent Dubuquoy, Romain Barnouin, Jean-Sebastien Annicotte, Benjamin Magnier, Mario Notti, Nadia Corazza, Maria Cristina Antal, Daniel Metzger, Pierre Desreumaux, Thomas Brunner, Johan Auwerx, Kristina Schoonjans
Proc Natl Acad Sci U S A. 2007 Aug 7; 104(32): 13098–13103. Published online 2007 Aug 1. doi: 10.1073/pnas.0702440104
PMCID:
PMC1941823
ArticlePDF–1.2M
11.
Liver Receptor Homolog 1 Is a Negative Regulator of the Hepatic Acute-Phase Response
Nicolas Venteclef, Jason C. Smith, Bryan Goodwin, Philippe Delerive
Mol Cell Biol. 2006 Sep; 26(18): 6799–6807. doi: 10.1128/MCB.00579-06
PMCID:
PMC1592867
ArticlePDF–278K
12.
Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
Madeleine Birgersson, Rajitha Indukuri, Linnéa Lindquist, Lina Stepanauskaite, Qing Luo, Qiaolin Deng, Amena Archer, Cecilia Williams
BMC Biol. 2023; 21: 277. Published online 2023 Nov 29. doi: 10.1186/s12915-023-01773-1
PMCID:
PMC10688478
ArticlePDF–3.9M
13.
LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis
Jijia Hu, Zongwei Zhang, Hongtu Hu, Keju Yang, Zijing Zhu, Qian Yang, Wei Liang
Cell Prolif. 2023 Nov; 56(11): e13479. Published online 2023 Apr 13. doi: 10.1111/cpr.13479
PMCID:
PMC10623971
ArticlePDF–6.3M
14.
Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids
Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Feodora Kostadinova, Corinne Urwyler, Verena M. Merk, Mario Noti, Israel Toja da Silva, Konstantin Bode, Fatima Nahle, Anna Pia Plazzo, Julia Koerner, Regula Stuber, Constantin Menche, Eva Karamitopoulou, Henner F. Farin, Kenneth J. Gollob, Thomas Brunner
Mol Oncol. 2023 Aug; 17(8): 1545–1566. Published online 2023 Mar 9. doi: 10.1002/1878-0261.13414
PMCID:
PMC10399709
ArticlePDF–3.7M
15.
NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function
Eugenia Martin Vázquez, Nadia Cobo-Vuilleumier, Raquel Araujo Legido, Sandra Marín-Cañas, Emanuele Nola, Akaitz Dorronsoro, Lucia López Bermudo, Alejandra Crespo, Silvana Y. Romero-Zerbo, Maria García-Fernández, Alejandro Martin Montalvo, Anabel Rojas, Valentine Comaills, Francisco J. Bérmudez-Silva, Maureen Gannon, Franz Martin, Decio Eizirik, Petra I. Lorenzo, Benoit R. Gauthier
iScience. 2022 May 20; 25(5): 104345. Published online 2022 May 2. doi: 10.1016/j.isci.2022.104345
PMCID:
PMC9117883
ArticlePDF–5.0M
16.
Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis
Kellie S. Agrimson, Anna Minkina, Danielle Sadowski, Andrew Wheeler, Mark W. Murphy, Micah D. Gearhart, Vivian J. Bardwell, David Zarkower
PLoS Genet. 2022 Feb; 18(2): e1010088. Published online 2022 Feb 22. doi: 10.1371/journal.pgen.1010088
PMCID:
PMC8896720
ArticlePDF–9.3M
17.
Perilipin 5 is a novel target of nuclear receptor LRH-1 to regulate hepatic triglycerides metabolism
Rubee Pantha, Jae-Ho Lee, Jae-Hoon Bae, Eun Hee Koh, Minsang Shin, Dae-Kyu Song, Seung-Soon Im
BMB Rep. 2021 Sep 30; 54(9): 476–481. Published online 2021 Sep 30. doi: 10.5483/BMBRep.2021.54.9.051
PMCID:
PMC8505233
ArticlePDF–1.5M
18.
The combined action of Esrrb and Nr5a2 is essential for murine naïve pluripotency
Nicola Festuccia, Nick Owens, Almira Chervova, Agnès Dubois, Pablo Navarro
Development. 2021 Sep 1; 148(17): dev199604. Published online 2021 Sep 10. doi: 10.1242/dev.199604
PMCID:
PMC8451941
Article
19.
A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation
Marie-Charlotte Meinsohn, Camilla H. K. Hughes, Anthony Estienne, Hatice D. Saatcioglu, David Pépin, Raj Duggavathi, Bruce D. Murphy
Sci Rep. 2021; 11: 1079. Published online 2021 Jan 13. doi: 10.1038/s41598-020-80178-4
PMCID:
PMC7807074
ArticlePDF–10M
20.
Methyl-sensing nuclear receptor Liver Receptor Homolog-1 regulates mitochondrial function in mouse hepatocytes
Sungwoo Choi, Bingning Dong, Chih-Chun Janet Lin, Mi Jeong Heo, Kang Ho Kim, Zhen Sun, Martin Wagner, Jae Myoung Suh, Meng C. Wang, David D. Moore
Hepatology. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Hepatology. 2020 Mar; 71(3): 1055–1069. Published online 2019 Dec 23. doi: 10.1002/hep.30884
PMCID:
PMC6987012
ArticlePDF–1.6M

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