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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 79182912.

Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine

Trevor Teafatiller, Christopher W. Heskett, Anshu Agrawal, Jonathan S. Marchant, Janet E. Baulch, Munjal M. Acharya, Veedamali S. Subramanian

Nutrients. 2021 Feb; 13(2): 617. Published online 2021 Feb 14. doi: 10.3390/nu13020617

PMCID:: PMC7918291

Article PDF–1.7M

Select item 73357863.

Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways

Hyeonho Kim, Dongwook Kim, Jinhu Kim, Hee-Yoon Lee, Dongseok Park, Hyeyeon Kang, Keiko Matsuda, Fredrik H. Sterky, Michisuke Yuzaki, Jin Young Kim, Se-Young Choi, Jaewon Ko, Ji Won Um

J Biol Chem. 2020 Jul 3; 295(27): 9244–9262. Published online 2020 May 19. doi: 10.1074/jbc.RA120.013077

PMCID:: PMC7335786

Article PDF–9.3M

Select item 101653574.

Brain p3‐Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β‐peptide

Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Kensaku Kasuga, Ayano Kimura, Koichi Moteki, Ruriko Abe, Shungo Adachi, Shoich Kinoshita, Kumiko Yoshizawa‐Kumagaye, Hideki Nishio, Takashi Saito, Takaomi C Saido, Tohru Yamamoto, Masaki Nishimura, Hidenori Taru, Yuriko Sobu, Hiroyuki Ohba, Shingo Nishiyama, Norihiro Harada, Takeshi Ikeuchi, Hideo Tsukada, Yasuomi Ouchi, Toshiharu Suzuki

EMBO Mol Med. 2023 May; 15(5): e17052. Published online 2023 Mar 30. doi: 10.15252/emmm.202217052

PMCID:: PMC10165357

Article PDF–2.1M

Select item 92541265.

CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue

Ningning Bai, Xuhong Lu, Li Jin, Miriayi Alimujiang, Jingyuan Ma, Fan Hu, Yuejie Xu, Jingjing Sun, Jun Xu, Rong Zhang, Junfeng Han, Cheng Hu, Ying Yang

Mol Metab. 2022 Sep; 63: 101531. Published online 2022 Jun 24. doi: 10.1016/j.molmet.2022.101531

PMCID:: PMC9254126

Article PDF–2.8M

Select item 72724016.

Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3

Sung-Jin Kim, Yong Taek Jeong, Se Rok Jeong, Munsu Park, Hye Sun Go, Mi Young Kim, Je Kyung Seong, Ki Woo Kim, Jeong Taeg Seo, Chul Hoon Kim, Ji Hyun Lee, Seok Jun Moon

Exp Mol Med. 2020 May; 52(5): 793–803. Published online 2020 May 7. doi: 10.1038/s12276-020-0419-8

PMCID:: PMC7272401

Article PDF–3.6M

Select item 90643007.

Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum

Zhihui Liu, Man Jiang, Kif Liakath-Ali, Alessandra Sclip, Jaewon Ko, Roger Shen Zhang, Thomas C Südhof

eLife. 2022; 11: e70664. Published online 2022 Apr 14. doi: 10.7554/eLife.70664

PMCID:: PMC9064300

Article PDF–16M

Select item 73631528.

Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α–deficient mice

Naoya Gotoh, Yuhki Saito, Saori Hata, Haruka Saito, Daiki Ojima, Chiaki Murayama, Mayo Shigeta, Takaya Abe, Daijiro Konno, Fumio Matsuzaki, Toshiharu Suzuki, Tohru Yamamoto

J Biol Chem. 2020 Jul 10; 295(28): 9650–9662. Published online 2020 May 27. doi: 10.1074/jbc.RA119.012386

PMCID:: PMC7363152

Article PDF–1.9M

Select item 65891399.

Innervation of Thermogenic Adipose Tissue via a Calsyntenin-3β/S100b Axis

Xing Zeng, Mengchen Ye, Jon M. Resch, Mark P. Jedrychowski, Bo Hu, Bradford B. Lowell, David D. Ginty, Bruce M. Spiegelman

Nature. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Nature. 2019 May; 569(7755): 229–235. Published online 2019 May 1. doi: 10.1038/s41586-019-1156-9

PMCID:: PMC6589139

Article PDF–5.8M

Select item 382169610.

The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development

Katherine L. Pettem, Daisaku Yokomaku, Lin Luo, Michael W. Linhoff, Tuhina Prasad, Steven A. Connor, Tabrez J. Siddiqui, Hiroshi Kawabe, Fang Chen, Ling Zhang, Gabby Rudenko, Yu Tian Wang, Nils Brose, Ann Marie Craig

Neuron. Author manuscript; available in PMC 2014 Oct 2.

Published in final edited form as: Neuron. 2013 Oct 2; 80(1): 10.1016/j.neuron.2013.07.016. Published online 2013 Oct 2. doi: 10.1016/j.neuron.2013.07.016

PMCID:: PMC3821696

Article PDF–7.8M

Select item 984210811.

Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake

Veedamali S. Subramanian, Trevor Teafatiller, Janielle Vidal, Gihan S. Gunaratne, Carlos J. Rodriguez-Ortiz, Masashi Kitazawa, Jonathan S. Marchant

Int J Biol Macromol. Author manuscript; available in PMC 2023 Jan 16.

Published in final edited form as: Int J Biol Macromol. 2021 Dec 1; 192: 1178–1184. Published online 2021 Oct 18. doi: 10.1016/j.ijbiomac.2021.10.058

PMCID:: PMC9842108

Article PDF–671K

Select item 999521912.

CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization

Kevin Qian, Marcus J. Tol, Jin Wu, Lauren F. Uchiyama, Xu Xiao, Liujuan Cui, Alexander H. Bedard, Thomas A. Weston, Pradeep S. Rajendran, Laurent Vergnes, Yuta Shimanaka, Yesheng Yin, Yasaman Jami-Alahmadi, Whitaker Cohn, Bryce T. Bajar, Chia-Ho Lin, Benita Jin, Laura A. DeNardo, Douglas L. Black, Julian P. Whitelegge, James A. Wohlschlegel, Karen Reue, Kalyanam Shivkumar, Feng-Jung Chen, Stephen G. Young, Peng Li, Peter Tontonoz

Nature. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Nature. 2023 Jan; 613(7942): 160–168. Published online 2022 Dec 7. doi: 10.1038/s41586-022-05507-1

PMCID:: PMC9995219

Article PDF–5.4M

Select item 705298713.

A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells

Kushani Shah, Gwendalyn D King, Hao Jiang

J Mol Cell Biol. 2020 Jan; 12(1): 4–16. Published online 2019 Aug 23. doi: 10.1093/jmcb/mjz036

PMCID:: PMC7052987

Article PDF–1.4M

Select item 737738714.

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalenceof Germline Recombination and Influencing Factors

Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, Wei-Hsiang Huang, Mary Anne Hutchison, Yu Itoh-Maruoka, Laura A. Lavery, Wei Li, Tomohiko Maruo, Junko Motohashi, Emily Ling-Lin Pai, Kenneth A. Pelkey, Ariane Pereira, Thomas Philips, Jennifer L. Sinclair, Jeff A. Stogsdill, Lisa Traunmüller, Jiexin Wang, Joke Wortel, Wenjia You, Nashat Abumaria, Kevin T. Beier, Nils Brose, Harold A. Burgess, Constance L. Cepko, Jean-François Cloutier, Cagla Eroglu, Sandra Goebbels, Pascal S. Kaeser, Jeremy N. Kay, Wei Lu, Liqun Luo, Kenji Mandai, Chris J. McBain, Klaus-Armin Nave, Marco A.M. Prado, Vania F. Prado, Jeffrey Rothstein, John L.R. Rubenstein, Gesine Saher, Kenji Sakimura, Joshua R. Sanes, Peter Scheiffele, Yoshimi Takai, Hisashi Umemori, Matthijs Verhage, Michisuke Yuzaki, Huda Yahya Zoghbi, Hiroshi Kawabe, Ann Marie Craig

Neuron. Author manuscript; available in PMC 2021 Apr 8.

Published in final edited form as: Neuron. 2020 Apr 8; 106(1): 37–65.e5. Published online 2020 Feb 5. doi: 10.1016/j.neuron.2020.01.008

PMCID:: PMC7377387

Article PDF–2.3M

Select item 410151915.

Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins

Ji Won Um, Gopal Pramanik, Ji Seung Ko, Min-Young Song, Dongmin Lee, Hyun Kim, Kang-Sik Park, Thomas C. Südhof, Katsuhiko Tabuchi, Jaewon Ko

Cell Rep. Author manuscript; available in PMC 2014 Sep 27.

Published in final edited form as: Cell Rep. 2014 Mar 27; 6(6): 1096–1109. Published online 2014 Mar 6. doi: 10.1016/j.celrep.2014.02.010

PMCID:: PMC4101519

Article PDF–3.3M

Select item 381794616.

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein

Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212

PMCID:: PMC3817946

Article

Select item 529582117.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Article PDF–3.0M

Select item 396495518.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Article PDF–5.7M

Select item 18788519.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Article PDF–287K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

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