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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
Critical roles of SMYD2 lysine methyltransferase in mediating renal fibroblast activation and kidney fibrosis
Lirong Liu, Feng Liu, Yingjie Guan, Jianan Zou, Chunyun Zhang, Chongxiang Xiong, Ting C. Zhao, George Bayliss, Xiaogang Li, Shougang Zhuang
FASEB J. Author manuscript; available in PMC 2022 May 20.
Published in final edited form as: FASEB J. 2021 Jul; 35(7): e21715. doi: 10.1096/fj.202000554RRR
PMCID:
PMC9122037
ArticlePDF–1.3M
3.
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation
Haibi Su, Chen Meng, Jie Xu, Zhenghua Su, Chenxi Xiao, Di Yang
Cell Death Dis. 2022 Oct; 13(10): 890. Published online 2022 Oct 21. doi: 10.1038/s41419-022-05321-7
PMCID:
PMC9586978
ArticlePDF–4.5M
4.
Histone methyltransferase Smyd2 contributes to blood‐brain barrier breakdown in stroke
Jinghuan Wang, Wen Zhong, Qianwen Cheng, Chenxi Xiao, Jie Xu, Zhenghua Su, Haibi Su, Xinhua Liu
Clin Transl Med. 2022 Mar; 12(3): e761. Published online 2022 Mar 16. doi: 10.1002/ctm2.761
PMCID:
PMC8926904
ArticlePDF–10M
5.
Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease
Linda Xiaoyan Li, Lucy X. Fan, Julie Xia Zhou, Jared J. Grantham, James P. Calvet, Julien Sage, Xiaogang Li
J Clin Invest. 2017 Jun 30; 127(7): 2751–2764. Published online 2017 Jun 12. doi: 10.1172/JCI90921
PMCID:
PMC5490754
ArticlePDF–3.6M
6.
Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis
Amna Sajjad, Tatyana Novoyatleva, Silvia Vergarajauregui, Christian Troidl, Ralph T Schermuly, Haley O. Tucker, Felix B Engel
Biochim Biophys Acta. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Nov; 1843(11): 2556–2562. Published online 2014 Jul 8. doi: 10.1016/j.bbamcr.2014.06.019
PMCID:
PMC4157957
ArticlePDF–874K
7.
The Histone Methyltransferase Smyd2 Is a Negative Regulator of Macrophage Activation by Suppressing Interleukin 6 (IL-6) and Tumor Necrosis Factor α (TNF-α) Production
Guiliang Xu, Guilin Liu, Sidong Xiong, Haiyan Liu, Xi Chen, Biao Zheng
J Biol Chem. 2015 Feb 27; 290(9): 5414–5423. Published online 2015 Jan 12. doi: 10.1074/jbc.M114.610345
PMCID:
PMC4342458
ArticlePDF–2.5M
8.
Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis
Sevgi Bagislar, Arianna Sabò, Theresia R. Kress, Mirko Doni, Paola Nicoli, Stefano Campaner, Bruno Amati
Oncotarget. 2016 Oct 11; 7(41): 66398–66415. Published online 2016 Sep 13. doi: 10.18632/oncotarget.12012
PMCID:
PMC5341809
ArticlePDF–4.3M
9.
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
Nicolas Reynoird, Pawel K. Mazur, Timo Stellfeld, Natasha M. Flores, Shane M. Lofgren, Scott M. Carlson, Elisabeth Brambilla, Pierre Hainaut, Ewa B. Kaznowska, Cheryl H. Arrowsmith, Purvesh Khatri, Carlo Stresemann, Or Gozani, Julien Sage
Genes Dev. 2016 Apr 1; 30(7): 772–785. doi: 10.1101/gad.275529.115
PMCID:
PMC4826394
ArticlePDF–1.4M
10.
Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization
Laura T. Donlin, Christian Andresen, Steffen Just, Eugene Rudensky, Christopher T. Pappas, Martina Kruger, Erica Y. Jacobs, Andreas Unger, Anke Zieseniss, Marc-Werner Dobenecker, Tobias Voelkel, Brian T. Chait, Carol C. Gregorio, Wolfgang Rottbauer, Alexander Tarakhovsky, Wolfgang A. Linke
Genes Dev. 2012 Jan 15; 26(2): 114–119. doi: 10.1101/gad.177758.111
PMCID:
PMC3273835
ArticlePDF–1.3M
11.
Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex
Mark A Brown, Robert J Sims, III, Paul D Gottlieb, Philip W Tucker
Mol Cancer. 2006; 5: 26. Published online 2006 Jun 28. doi: 10.1186/1476-4598-5-26
PMCID:
PMC1524980
ArticlePDF–892K
12.
Cardiac Deletion of Smyd2 Is Dispensable for Mouse Heart Development
Florian Diehl, Mark A. Brown, Machteld J. van Amerongen, Tatyana Novoyatleva, Astrid Wietelmann, June Harriss, Fulvia Ferrazzi, Thomas Böttger, Richard P. Harvey, Philip W. Tucker, Felix B. Engel
PLoS One. 2010; 5(3): e9748. Published online 2010 Mar 17. doi: 10.1371/journal.pone.0009748
PMCID:
PMC2840034
ArticlePDF–3.7M
13.
Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway
Shotaro Saita, Michiko Shirane, Tohru Ishitani, Nobuyuki Shimizu, Keiichi I. Nakayama
J Biol Chem. 2014 Sep 12; 289(37): 25639–25654. Published online 2014 Jul 30. doi: 10.1074/jbc.M114.558635
PMCID:
PMC4162168
ArticlePDF–5.4M
14.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
ArticlePDF–5.1M
15.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
16.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
ArticlePDF–493K
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
ArticlePDF–1.1M
18.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
ArticlePDF–481K
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
ArticlePDF–3.8M
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
ArticlePDF–140K

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