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Select item 109869761.

A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways

Gaochuang Peng, Tianran Liu, Xiaolan Qi, Yuzhe Wang, Jingjing Ren, Jiangling Peng, Xuguang Du, Siyu Hu, Sen Wu, Yaofeng Zhao, Dan Li, Haixue Zheng

PLoS Pathog. 2024 Mar; 20(3): e1012104. Published online 2024 Mar 21. doi: 10.1371/journal.ppat.1012104

PMCID:: PMC10986976

Article PDF–3.4M

Select item 94634402.

TOB1 attenuates IRF3-directed antiviral responses by recruiting HDAC8 to specifically suppress IFN-β expression

Zhongxia Yu, Lijuan Wang, Jing Zhao, Hui Song, Chunyuan Zhao, Wei Zhao, Mutian Jia

Commun Biol. 2022; 5: 943. Published online 2022 Sep 9. doi: 10.1038/s42003-022-03911-x

PMCID:: PMC9463440

Article PDF–2.4M

Select item 93380903.

TOB is an effector of the hippocampus-mediated acute stress response

Mohieldin M. M. Youssef, Hiro Taiyo Hamada, Esther Suk King Lai, Yuji Kiyama, Mohamed El-Tabbal, Hiroshi Kiyonari, Kohei Nakano, Bernd Kuhn, Tadashi Yamamoto

Transl Psychiatry. 2022; 12: 302. Published online 2022 Jul 29. doi: 10.1038/s41398-022-02078-7

PMCID:: PMC9338090

Article PDF–4.4M

Select item 88816724.

TOB1 Blocks Intestinal Mucosal Inflammation Through Inducing ID2-Mediated Suppression of Th1/Th17 Cell Immune Responses in IBD

Ritian Lin, Caiyun Ma, Leilei Fang, Chunjin Xu, Cui Zhang, Xiaohan Wu, Wei Wu, Ruixin Zhu, Yingzi Cong, Zhanju Liu

Cell Mol Gastroenterol Hepatol. 2022; 13(4): 1201–1221. Published online 2021 Dec 14. doi: 10.1016/j.jcmgh.2021.12.007

PMCID:: PMC8881672

Article PDF–8.3M

Select item 49928655.

Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis

Alessandro Didonna, Egle Cekanaviciute, Jorge R. Oksenberg, Sergio E. Baranzini

Sci Rep. 2016; 6: 31603. Published online 2016 Aug 22. doi: 10.1038/srep31603

PMCID:: PMC4992865

Article PDF–1.1M

Select item 36985246.

Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity

Ulf Schulze-Topphoff, Simona Casazza, Michel Varrin-Doyer, Kara Pekarek, Raymond A. Sobel, Stephen L. Hauser, Jorge R. Oksenberg, Scott S. Zamvil, Sergio E. Baranzini

J Exp Med. 2013 Jul 1; 210(7): 1301–1309. doi: 10.1084/jem.20121611

PMCID:: PMC3698524

Article PDF–2.7M

Select item 31553537.

Molecular Characterization of Tob1 in Muscle Development in Pigs

Jing Yuan, Ji-Yue Cao, Zhong-Lin Tang, Ning Wang, Kui Li

Int J Mol Sci. 2011; 12(7): 4315–4326. Published online 2011 Jul 4. doi: 10.3390/ijms12074315

PMCID:: PMC3155353

Article PDF–440K

Select item 28828438.

Tob1 is a constitutively expressed repressor of liver regeneration

Karen J. Ho, Nhue L. Do, Hasan H. Otu, Martin J. Dib, Xianghui Ren, Keiichi Enjyoji, Simon C. Robson, Ernest F. Terwilliger, Seth J. Karp

J Exp Med. 2010 Jun 7; 207(6): 1197–1208. doi: 10.1084/jem.20092434

PMCID:: PMC2882843

Article PDF–3.5M

Select item 4041009.

Tob deficiency superenhances osteoblastic activity after ovariectomy to block estrogen deficiency-induced osteoporosis

Michihiko Usui, Yutaka Yoshida, Kunikazu Tsuji, Kaoru Oikawa, Kohei Miyazono, Isao Ishikawa, Tadashi Yamamoto, Akira Nifuji, Masaki Noda

Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17): 6653–6658. Published online 2004 Apr 20. doi: 10.1073/pnas.0303093101

PMCID:: PMC404100

Article PDF–411K

Select item 624028710.

High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer

Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, Tianhui Hu

Mol Cancer. 2018; 17: 159. Published online 2018 Nov 17. doi: 10.1186/s12943-018-0907-9

PMCID:: PMC6240287

Article PDF–3.2M

Select item 406394811.

Nfatc2 and Tob1 Have Non-Overlapping Function in T Cell Negative Regulation and Tumorigenesis

Sarah L. May, Qing Zhou, Mitzi Lewellen, Cristan M. Carter, David Coffey, Steven L. Highfill, Christoph M. Bucher, Ilze Matise, Herbert C. Morse, III, M. Gerard O’Sullivan, Melissa Schutten, Charles Johnson, Donald Bellgrau, Bruce R. Blazar, Jaime F. Modiano

PLoS One. 2014; 9(6): e100629. Published online 2014 Jun 19. doi: 10.1371/journal.pone.0100629

PMCID:: PMC4063948

Article PDF–1.7M

Select item 19606312.

Mice lacking a transcriptional corepressor Tob are predisposed to cancer

Yutaka Yoshida, Takahisa Nakamura, Masato Komoda, Hitoshi Satoh, Toru Suzuki, Junko K. Tsuzuku, Takashi Miyasaka, Eri H. Yoshida, Hisashi Umemori, Reiko K. Kunisaki, Kenzaburo Tani, Shunsuke Ishii, Shigeo Mori, Masami Suganuma, Tetsuo Noda, Tadashi Yamamoto

Genes Dev. 2003 May 15; 17(10): 1201–1206. doi: 10.1101/gad.1088003

PMCID:: PMC196063

Article PDF–250K

Select item 481787313.

MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic Mice

Yan Li, Longkun Fan, Jiang Hu, Leilei Zhang, Li Liao, Shiyu Liu, Dan Wu, Ping Yang, Lijuan Shen, Jihua Chen, Yan Jin

Mol Ther. 2015 Aug; 23(8): 1349–1357. Prepublished online 2015 Jun 8. Published online 2015 Jun 30. doi: 10.1038/mt.2015.101

PMCID:: PMC4817873

Article PDF–2.0M

Select item 472649714.

Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7

Farhoud Faraji, Ying Hu, Howard H. Yang, Maxwell P. Lee, G. Sebastian Winkler, Markus Hafner, Kent W. Hunter

PLoS Genet. 2016 Jan; 12(1): e1005820. Published online 2016 Jan 25. doi: 10.1371/journal.pgen.1005820

PMCID:: PMC4726497

Article PDF–3.7M

Select item 259738915.

Lymphocyte quiescence factor Dpp2 is transcriptionally activated by KLF2 and TOB1

Pradeep Bista, Deanna Mele, Diana Velez Baez, Brigitte T. Huber

Mol Immunol. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Mol Immunol. 2008 Aug; 45(13): 3618–3623. Published online 2008 Jun 13. doi: 10.1016/j.molimm.2008.05.001

PMCID:: PMC2597389

Article PDF–554K

Select item 18631916.

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

Toru Suzuki, Junko K-Tsuzuku, Rieko Ajima, Takahisa Nakamura, Yutaka Yoshida, Tadashi Yamamoto

Genes Dev. 2002 Jun 1; 16(11): 1356–1370. doi: 10.1101/gad.962802

PMCID:: PMC186319

Article PDF–457K

Select item 469406717.

Apoptosis during embryonic tissue remodeling is accompanied by cell senescence

Carlos I. Lorda-Diez, Beatriz Garcia-Riart, Juan A. Montero, Joaquín Rodriguez-León, Juan A Garcia-Porrero, Juan M. Hurle

Aging (Albany NY) 2015 Nov; 7(11): 974–985. Published online 2015 Nov 14. doi: 10.18632/aging.100844

PMCID:: PMC4694067

Article PDF–2.3M

Select item 741416218.

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system

Rajiv A. Mohan, Fernanda M. Bosada, Jan H. van Weerd, Karel van Duijvenboden, Jianan Wang, Mathilda T. M. Mommersteeg, Ingeborg B. Hooijkaas, Vincent Wakker, Corrie de Gier-de Vries, Ruben Coronel, Gerard J. J. Boink, Jeroen Bakkers, Phil Barnett, Bas J. Boukens, Vincent M. Christoffels

Proc Natl Acad Sci U S A. 2020 Aug 4; 117(31): 18617–18626. Published online 2020 Jul 16. doi: 10.1073/pnas.1919379117

PMCID:: PMC7414162

Article PDF–1.7M

Select item 311015119.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Article PDF–2.0M

Select item 16551120.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Article PDF–217K

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