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Items: 1 to 20 of 27

1.
Topoisomerase IIIβ Deficiency Induces Neuro-Behavioral Changes and Brain Connectivity Alterations in Mice
Faiz Ur Rahman, You-Rim Kim, Eun-Kyeung Kim, Hae-rim Kim, Sang-Mi Cho, Chin-Soo Lee, Su Jin Kim, Kimi Araki, Ken-ichi Yamamura, Mi-Ni Lee, Seul Gi Park, Won-Kee Yoon, Kihoon Lee, Young-Suk Won, Hyoung-Chin Kim, Younghee Lee, Ho-Young Lee, Ki-Hoan Nam
Int J Mol Sci. 2021 Dec; 22(23): 12806. Published online 2021 Nov 26. doi: 10.3390/ijms222312806
PMCID:
PMC8657541
ArticlePDF–4.5M
2.
Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity
Yuyoung Joo, Yutong Xue, Yue Wang, Ross A. McDevitt, Nirnath Sah, Simone Bossi, Shuaikun Su, Seung Kyu Lee, Wei Peng, Aoji Xie, Yongqing Zhang, Yi Ding, Wai Lim Ku, Soumita Ghosh, Kenneth Fishbein, Weiping Shen, Richard Spencer, Kevin Becker, Keji Zhao, Mark P. Mattson, Henriette van Praag, Alexei Sharov, Weidong Wang
Nat Commun. 2020; 11: 3143. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16884-4
PMCID:
PMC7305123
ArticlePDF–3.5M
3.
Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders
Georg Stoll, Olli P. H. Pietiläinen, Bastian Linder, Jaana Suvisaari, Cornelia Brosi, William Hennah, Virpi Leppä, Minna Torniainen, Samuli Ripatti, Sirpa Ala-Mello, Oliver Plöttner, Karola Rehnström, Annamari Tuulio-Henriksson, Teppo Varilo, Jonna Tallila, Kati Kristiansson, Matti Isohanni, Jaakko Kaprio, Johan G. Eriksson, Olli T. Raitakari, Terho Lehtimäki, Marjo-Riitta Jarvelin, Veikko Salomaa, Matthew Hurles, Hreinn Stefansson, Leena Peltonen, Patrick F. Sullivan, Tiina Paunio, Jouko Lönnqvist, Mark J. Daly, Utz Fischer, Nelson B. Freimer, Aarno Palotie
Nat Neurosci. Author manuscript; available in PMC 2014 Apr 15.
Published in final edited form as: Nat Neurosci. 2013 Sep; 16(9): 1228–1237. Published online 2013 Aug 4. doi: 10.1038/nn.3484
PMCID:
PMC3986889
ArticlePDF–1.9M
4.
Development of autoimmunity in mice lacking DNA topoisomerase 3β
Kelvin Y. Kwan, Rebecca J. Greenwald, Subhasis Mohanty, Arlene H. Sharpe, Albert C. Shaw, James C. Wang
Proc Natl Acad Sci U S A. 2007 May 29; 104(22): 9242–9247. Published online 2007 May 21. doi: 10.1073/pnas.0703587104
PMCID:
PMC1890479
ArticlePDF–1.4M
5.
Mice lacking DNA topoisomerase IIIβ develop to maturity but show a reduced mean lifespan
Kelvin Y. Kwan, James C. Wang
Proc Natl Acad Sci U S A. 2001 May 8; 98(10): 5717–5721. Published online 2001 May 1. doi: 10.1073/pnas.101132498
PMCID:
PMC33279
ArticlePDF–201K
6.
Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3β
Subhasis Mohanty, Terrence Town, Tomohito Yagi, Christina Scheidig, Kelvin Y. Kwan, Heather G. Allore, Richard A. Flavell, Albert C. Shaw
Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13): 5063–5068. Published online 2008 Mar 26. doi: 10.1073/pnas.0801235105
PMCID:
PMC2278186
ArticlePDF–1.4M
7.
Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase IIIβ
Kelvin Y. Kwan, Peter B. Moens, James C. Wang
Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5): 2526–2531. Published online 2003 Feb 18. doi: 10.1073/pnas.0437998100
PMCID:
PMC151374
ArticlePDF–395K
8.
Top3ß is an RNA topoisomerase that works with Fragile X syndrome protein to promote synapse formation
Dongyi Xu, Weiping Shen, Rong Guo, Yutong Xue, Wei Peng, Jian Sima, Jay Yang, Alexei Sharov, Subramanya Srikantan, Jiandong Yang, David Fox, 3rd, Yong Qian, Jennifer L. Martindale, Yulan Piao, James Machamer, Samit R. Joshi, Subhasis Mohanty, Albert C. Shaw, Thomas E. Lloyd, Grant W. Brown, Minoru S.H. Ko, Myriam Gorospe, Sige Zou, Weidong Wang
Nat Neurosci. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Nat Neurosci. 2013 Sep; 16(9): 1238–1247. Published online 2013 Aug 4. doi: 10.1038/nn.3479
PMCID:
PMC3853347
ArticlePDF–1.7M
9.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
ArticlePDF–3.3M
10.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
Article
11.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
ArticlePDF–7.7M
12.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
ArticlePDF–2.3M
13.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
ArticlePDF–5.1M
14.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
ArticlePDF–287K
15.
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin
Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064
PMCID:
PMC165511
ArticlePDF–217K
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
17.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
ArticlePDF–847K
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
ArticlePDF–493K
19.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
ArticlePDF–1.1M

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