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Select item 83503251.

A20 Establishes Negative Feedback With TRAF6/NF-κB and Attenuates Early Brain Injury After Experimental Subarachnoid Hemorrhage

Hong-Ji Deng, QuZhen Deji, WangDui Zhaba, Jia-Qiang Liu, Sheng-Qing Gao, Yan-Ling Han, Meng-Liang Zhou, Chun-Xi Wang

Front Immunol. 2021; 12: 623256. Published online 2021 Jul 26. doi: 10.3389/fimmu.2021.623256

PMCID:: PMC8350325

Article PDF–10M

Select item 70067142.

A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T Cell Activation

Xiaohan Lu, Nathan P. Rudemiller, Yi Wen, Jiafa Ren, Gianna E. Hammer, Robert Griffiths, Jamie R. Privratsky, Bo Yang, Matthew A. Sparks, Steven D. Crowley

Circ Res. Author manuscript; available in PMC 2020 Dec 6.

Published in final edited form as: Circ Res. 2019 Dec 6; 125(12): 1055–1066. Published online 2019 Oct 21. doi: 10.1161/CIRCRESAHA.119.315343

PMCID:: PMC7006714

Article PDF–1.9M

Select item 67565373.

Regulation of NF-κB- and STAT1-mediated plasmacytoid dendritic cell functions by A20

Pham Ngoc Duy, Nguyen Thu Thuy, Bui Kieu Trang, Nguyen Hoang Giang, Nguyen Thi Hong Van, Nguyen Thi Xuan

PLoS One. 2019; 14(9): e0222697. Published online 2019 Sep 23. doi: 10.1371/journal.pone.0222697

PMCID:: PMC6756537

Article PDF–1.4M

Select item 65065864.

Herbs-partitioned moxibustion alleviates aberrant intestinal epithelial cell apoptosis by upregulating A20 expression in a mouse model of Crohn’s disease

Jing Zhou, Lu-Yi Wu, Liu Chen, Ya-Jing Guo, Yi Sun, Tao Li, Ji-Meng Zhao, Chun-Hui Bao, Huan-Gan Wu, Yin Shi

World J Gastroenterol. 2019 May 7; 25(17): 2071–2085. Published online 2019 May 7. doi: 10.3748/wjg.v25.i17.2071

PMCID:: PMC6506586

Article PDF–19M

Select item 60701755.

Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features

Xiaoyan Wang, Abeer Shaalan, Silvia Liefers, Julie Coudenys, Dirk Elewaut, Gordon B. Proctor, Hendrika Bootsma, Frans G. M. Kroese, Sarah Pringle

PLoS One. 2018; 13(8): e0200212. Published online 2018 Aug 1. doi: 10.1371/journal.pone.0200212

PMCID:: PMC6070175

Article PDF–7.5M

Select item 59683876.

M Protein of Group a Streptococcus Plays an Essential Role in Inducing High Expression of A20 in Macrophages Resulting in the Downregulation of Inflammatory Response in Lung Tissue

Cuiqing Ma, Xue Gao, Shuhui Wu, Ling Zhang, Jiachao Wang, Zhengzheng Zhang, Zhiyan Yao, Xiaotian Song, Wenjian Li, Xiurong Wang, Huidong Feng, Lin Wei

Front Cell Infect Microbiol. 2018; 8: 131. Published online 2018 May 11. doi: 10.3389/fcimb.2018.00131

PMCID:: PMC5968387

Article PDF–3.1M

Select item 58114927.

Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models

Upneet K. Sokhi, Mark P. Liber, Laura Frye, Sungho Park, Kyuho Kang, Tania Pannellini, Baohong Zhao, Rada Norinsky, Lionel B. Ivashkiv, Shiaoching Gong

Nat Commun. 2018; 9: 658. Published online 2018 Feb 13. doi: 10.1038/s41467-018-03081-7

PMCID:: PMC5811492

Article PDF–5.7M

Select item 56171218.

A20 Restrains Thymic Regulatory T Cell Development

Julius Clemens Fischer, Vera Otten, Maike Kober, Christoph Drees, Marc Rosenbaum, Martina Schmickl, Simon Heidegger, Rudi Beyaert, Geert van Loo, Xian Chang Li, Christian Peschel, Marc Schmidt-Supprian, Tobias Haas, Silvia Spoerl, Hendrik Poeck

J Immunol. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: J Immunol. 2017 Oct 1; 199(7): 2356–2365. Published online 2017 Aug 25. doi: 10.4049/jimmunol.1602102

PMCID:: PMC5617121

Article PDF–1.2M

Select item 51778699.

A20 Curtails Primary but Augments Secondary CD8⁺ T Cell Responses in Intracellular Bacterial Infection

Sissy Just, Gopala Nishanth, Jörn H. Buchbinder, Xu Wang, Michael Naumann, Inna Lavrik, Dirk Schlüter

Sci Rep. 2016; 6: 39796. Published online 2016 Dec 22. doi: 10.1038/srep39796

PMCID:: PMC5177869

Article PDF–2.6M

Select item 495695110.

A20 plays a critical role in the immunoregulatory function of mesenchymal stem cells

Rui‐Jie Dang, Yan‐Mei Yang, Lei Zhang, Dian‐Chao Cui, Bangxing Hong, Ping Li, Qiuxia Lin, Yan Wang, Qi‐Yu Wang, Fengjun Xiao, Ning Mao, Changyong Wang, Xiao‐Xia Jiang, Ning Wen

J Cell Mol Med. 2016 Aug; 20(8): 1550–1560. Published online 2016 Mar 29. doi: 10.1111/jcmm.12849

PMCID:: PMC4956951

Article PDF–1.3M

Select item 481611011.

Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regeneration

P Studer, C G da Silva, J M Revuelta Cervantes, A Mele, E Csizmadia, J J Siracuse, S M Damrauer, C R Peterson, D Candinas, D M Stroka, A Ma, M Bhasin, C Ferran

Cell Death Differ. 2015 Dec; 22(12): 2068–2077. Published online 2015 May 15. doi: 10.1038/cdd.2015.52

PMCID:: PMC4816110

Article PDF–2.6M

Select item 473139012.

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

Jonathan Maelfait, Kenny Roose, Lars Vereecke, Conor Mc Guire, Mozes Sze, Martijn J. Schuijs, Monique Willart, Lorena Itati Ibañez, Hamida Hammad, Bart N. Lambrecht, Rudi Beyaert, Xavier Saelens, Geert van Loo

PLoS Pathog. 2016 Jan; 12(1): e1005410. Published online 2016 Jan 27. doi: 10.1371/journal.ppat.1005410

PMCID:: PMC4731390

Article PDF–2.6M

Select item 421699313.

Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice

Stephen F. Murphy, Lesley Rhee, Wesley A. Grimm, Christopher R. Weber, Jeannette S. Messer, James P. Lodolce, Jonathan E. Chang, Sarah J. Bartulis, Thomas Nero, Renata A. Kukla, Gordon MacDougall, Charles Binghay, Lauren E. Kolodziej, David L. Boone

Am J Physiol Gastrointest Liver Physiol. 2014 Nov 1; 307(9): G871–G882. Published online 2014 Sep 18. doi: 10.1152/ajpgi.00020.2014

PMCID:: PMC4216993

Article

Select item 419698114.

The deubiquitinase activity of A20 is dispensable for NF-κB signaling

Arnab De, Teruki Dainichi, Chozha Vendan Rathinam, Sankar Ghosh

EMBO Rep. 2014 Jul; 15(7): 775–783. Published online 2014 May 30. doi: 10.15252/embr.201338305

PMCID:: PMC4196981

Article PDF–1.6M

Select item 412860615.

A20 deficiency causes spontaneous neuroinflammation in mice

Renata Padilha Guedes, Eva Csizmadia, Herwig P Moll, Averil Ma, Christiane Ferran, Cleide Gonçalves da Silva

J Neuroinflammation. 2014; 11: 122. Published online 2014 Jul 16. doi: 10.1186/1742-2094-11-122

PMCID:: PMC4128606

Article PDF–2.4M

Select item 362674916.

A20 Promotes Liver Regeneration by Decreasing SOCS3 Expression to Enhance IL-6/STAT3 Proliferative Signals

Cleide G. da Silva, Peter Studer, Marco Skroch, Jerome Mahiou, Darlan C. Minussi, Clayton R. Peterson, Suzhuei W. Wilson, Virendra I. Patel, Averil Ma, Eva Csizmadia, Christiane Ferran

Hepatology. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Hepatology. 2013 May; 57(5): 2014–2025. Published online 2013 Apr 5. doi: 10.1002/hep.26197

PMCID:: PMC3626749

Article PDF–2.9M

Select item 349213917.

A20 Controls Macrophage to Elicit Potent Cytotoxic CD4⁺ T Cell Response

Lifeng Wang, Bangxing Hong, Xiaoxia Jiang, Lindsey Jones, Si-Yi Chen, Xue F. Huang

PLoS One. 2012; 7(11): e48930. Published online 2012 Nov 7. doi: 10.1371/journal.pone.0048930

PMCID:: PMC3492139

Article PDF–2.1M

Select item 346092718.

A20 (TNFAIP3) Alleviates CVB3-Induced Myocarditis via Inhibiting NF-κB Signaling

Jun Gui, Yan Yue, Ruizhen Chen, Wei Xu, Sidong Xiong

PLoS One. 2012; 7(9): e46515. Published online 2012 Sep 28. doi: 10.1371/journal.pone.0046515

PMCID:: PMC3460927

Article PDF–2.2M

Select item 340456919.

Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis

Lesley Rhee, Stephen F. Murphy, Lauren E. Kolodziej, Wesley A. Grimm, Christopher R. Weber, James P. Lodolce, Jonathan E. Chang, Sarah J. Bartulis, Jeannette S. Messer, Jeff R. Schneider, Shirley Paski, Thomas M. Nero, David L. Boone

Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2): G220–G227. Published online 2012 May 17. doi: 10.1152/ajpgi.00077.2012