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Select item 102089751.

TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

Huihui Qi, Li Luo, Caijing Lu, Runze Chen, Xianyao Zhou, Xiaohui Zhang, Yichang Jia

Mol Psychiatry. 2023; 28(4): 1703–1717. Published online 2023 Feb 13. doi: 10.1038/s41380-023-01993-5

Correction in:: Mol Psychiatry. 2023; 28(4): 1718.

PMCID:: PMC10208975

Article PDF–3.4M

Select item 100362872.

Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

Da Som Lee, Tae Hyeon An, Hyunmi Kim, Eunsun Jung, Gyeonghun Kim, Seung Yeon Oh, Jun Seok Kim, Hye Jin Chun, Jaeeun Jung, Eun-Woo Lee, Baek-Soo Han, Dai Hoon Han, Yong-Ho Lee, Tae-Su Han, Keun Hur, Chul-Ho Lee, Dae-Soo Kim, Won Kon Kim, Jun Won Park, Seung-Hoi Koo, Je Kyung Seong, Sang Chul Lee, Hail Kim, Kwang-Hee Bae, Kyoung-Jin Oh

Diabetologia. 2023; 66(5): 931–954. Published online 2023 Feb 10. doi: 10.1007/s00125-023-05878-8

PMCID:: PMC10036287

Article PDF–13M

Select item 97720703.

TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression

Fuzheng Guo, Yan Wang

Glia. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Glia. 2023 Feb; 71(2): 143–154. Published online 2022 Jul 16. doi: 10.1002/glia.24249

PMCID:: PMC9772070

Article PDF–2.7M

Select item 92982774.

Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Ye Yang, Manjun Shen, Li Li, Yujun Long, Lu Wang, Bing Lang, Renrong Wu

Front Cell Dev Biol. 2022; 10: 890472. Published online 2022 Jul 6. doi: 10.3389/fcell.2022.890472

PMCID:: PMC9298277

Article PDF–2.5M

Select item 91698255.

T-cell factor 7L2 is a novel regulator of osteoblast functions that acts in part by modulation of hypoxia signaling

Subburaman Mohan, Chandrasekhar Kesavan

Am J Physiol Endocrinol Metab. 2022 Jun 1; 322(6): E528–E539. Published online 2022 Apr 25. doi: 10.1152/ajpendo.00035.2022

PMCID:: PMC9169825

Article

Select item 75676536.

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

Marie-Sophie Nguyen-Tu, Aida Martinez-Sanchez, Isabelle Leclerc, Guy A. Rutter, Gabriela da Silva Xavier

Diabetologia. 2021; 64(1): 129–141. Published online 2020 Oct 17. doi: 10.1007/s00125-020-05292-4

PMCID:: PMC7567653

Article PDF–1.2M

Select item 65318147.

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism

Gisela Geoghegan, Judith Simcox, Marcus M. Seldin, Timothy J. Parnell, Chris Stubben, Steven Just, Lori Begaye, Aldons J. Lusis, Claudio J. Villanueva

Mol Metab. 2019 Jun; 24: 44–63. Published online 2019 Mar 14. doi: 10.1016/j.molmet.2019.03.003

PMCID:: PMC6531814

Article PDF–3.1M

Select item 61012158.

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2 null mice

G. da Silva Xavier, A. Mondragon, G. Sun, L. Chen, J.A. McGinty, P.M. French, G.A. Rutter

Diabetologia. Author manuscript; available in PMC 2018 Aug 20.

Published in final edited form as: Diabetologia. 2012 Oct; 55(10): 2667–2676. Published online 2012 Jun 21. doi: 10.1007/s00125-012-2600-7

PMCID:: PMC6101215

Article PDF–1.5M

Select item 55620629.

Transcription factor 7 like 2 promotes oligodendrocyte differentiation and remyelination

Chao Weng, Man Ding, Shanghua Fan, Qian Cao, Zuneng Lu

Mol Med Rep. 2017 Aug; 16(2): 1864–1870. Published online 2017 Jun 22. doi: 10.3892/mmr.2017.6843

PMCID:: PMC5562062

Article PDF–1.6M

Select item 542396010.

Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice

Gabriela da Silva Xavier, Angeles Mondragon, Vishnou Mourougavelou, Céline Cruciani-Guglielmacci, Jessica Denom, Pedro Luis Herrera, Christophe Magnan, Guy A. Rutter

Diabetologia. 2017; 60(6): 1043–1050. Published online 2017 Mar 25. doi: 10.1007/s00125-017-4242-2

PMCID:: PMC5423960

Article PDF–1.4M

Select item 512976811.

Tcf7l2 localization of putative stem/progenitor cells in mouse conjunctiva

Yadan Quan, Xinchun Zhang, Siying Xu, Kang Li, Feng Zhu, Qian Li, Xianxian Cai, Rong Lu

Am J Physiol Cell Physiol. 2016 Aug 1; 311(2): C246–C254. Published online 2016 Jun 8. doi: 10.1152/ajpcell.00014.2016

PMCID:: PMC5129768

Article

Select item 432144612.

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass

Ryan K. Mitchell, Angeles Mondragon, Lingling Chen, James A. Mcginty, Paul M. French, Jorge Ferrer, Bernard Thorens, David J. Hodson, Guy A. Rutter, Gabriela Da Silva Xavier

Hum Mol Genet. 2015 Mar 1; 24(5): 1390–1399. Published online 2014 Oct 29. doi: 10.1093/hmg/ddu553

PMCID:: PMC4321446

Article PDF–708K

Select item 417693313.

Expression of the Diabetes-Associated Gene TCF7L2 in Adult Mouse Brain

SYANN LEE, CHARLOTTE E. LEE, CAROL F. ELIAS, JOEL K. ELMQUIST

J Comp Neurol. Author manuscript; available in PMC 2014 Sep 27.

Published in final edited form as: J Comp Neurol. 2009 Dec 20; 517(6): 925–939. doi: 10.1002/cne.22199

PMCID:: PMC4176933

Article PDF–6.5M

Select item 345511214.

Review of the Neuroanatomic Landscape Implicated in Glucose Sensing and Regulation of Nutrient Signaling: Immunophenotypic Localization of Diabetes Gene Tcf7l2 in the Developing Murine Brain

Cyprian Weaver, Nolan Turner, Jennifer Hall

J Chem Neuroanat. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: J Chem Neuroanat. 2012 Oct; 45(1-2): 1–17. Published online 2012 Jul 13. doi: 10.1016/j.jchemneu.2012.06.002

PMCID:: PMC3455112

Article PDF–6.3M

Select item 337288315.

Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice

Hyekyung Yang, Qing Li, Jong-Hwan Lee, Yan Shu

Int J Biol Sci. 2012; 8(6): 791–801. Published online 2012 Jun 5. doi: 10.7150/ijbs.4568

PMCID:: PMC3372883

Article PDF–1.4M

Select item 320317016.

Modulation of Tcf7l2 Expression Alters Behavior in Mice

Daniel Savic, Margaret G. Distler, Greta Sokoloff, Nancy A. Shanahan, Stephanie C. Dulawa, Abraham A. Palmer, Marcelo A. Nobrega

PLoS One. 2011; 6(10): e26897. Published online 2011 Oct 27. doi: 10.1371/journal.pone.0026897

PMCID:: PMC3203170

Article PDF–361K

Select item 962437417.

TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk

Neha Bhat, Fatemehsadat Esteghamat, Bal Krishna Chaube, Kushan Gunawardhana, Mitra Mani, Clay Thames, Dhanpat Jain, Henry N. Ginsberg, Carlos Fernandes-Hernando, Arya Mani

FASEB J. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: FASEB J. 2022 Mar; 36(3): e22185. doi: 10.1096/fj.202101607R

Correction in:: FASEB J. 2022 Mar; 36(3): e22217.

PMCID:: PMC9624374

Article PDF–4.1M

Select item 811587918.

The Wnt Effector TCF7l2 Promotes Oligodendroglial Differentiation by Repressing Autocrine BMP4-Mediated Signaling

Sheng Zhang, Yan Wang, Xiaoqing Zhu, Lanying Song, Xinhua Zhan, Edric Ma, Jennifer McDonough, Hui Fu, Franca Cambi, Judith Grinspan, Fuzheng Guo

J Neurosci. 2021 Feb 24; 41(8): 1650–1664. doi: 10.1523/JNEUROSCI.2386-20.2021

PMCID:: PMC8115879

Article PDF–5.5M

Select item 586086319.

The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function

Xi Chen, Iriscilla Ayala, Chris Shannon, Marcel Fourcaudot, Nikhil K. Acharya, Christopher P. Jenkinson, Sami Heikkinen, Luke Norton

Diabetes. 2018 Apr; 67(4): 554–568. Published online 2018 Jan 9. doi: 10.2337/db17-0318

PMCID:: PMC5860863

Article PDF–2.6M

Select item 547434420.

Environmental Enrichment Induces Pericyte and IgA-Dependent Wound Repair and Lifespan Extension in a Colon Tumor Model

Benjamin D. Bice, Megan R. Stephens, Stephanie J. Georges, Ashlee R. Venancio, Peter C. Bermant, Annika V. Warncke, Kajsa E. Affolter, Julio R. Hidalgo, Melinda L. Angus-Hill

Cell Rep. Author manuscript; available in PMC 2018 Apr 25.

Published in final edited form as: Cell Rep. 2017 Apr 25; 19(4): 760–773. doi: 10.1016/j.celrep.2017.04.006